HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Ornston, L. N. Search for Related Content PubMed PubMed Citation Articles by Ornston, L. N. Social Bookmarking                      What's this?

The Conversion of Catechol and Protocatechuate to ß-Ketoadipate by Pseudomonas putida

IV. REGULATION

From the ¹ From the Department of Bacteriology and Immunology, University of California, Berkeley, California 94720

Study of the regulation of the syntheses of enzymes of the catechol and protocatechuate pathways in Pseudomonas putida has shown that two groups of enzymes are subject to coordinate control. cis,cis-Muconate-lactonizing enzyme and muconolactone isomerase, which are uniquely associated with the catechol pathway, constitute the first coordinate block of enzymes. The synthesis of these enzymes, as well as that of catechol oxygenase (which is regulated independently), seems to be induced by cis,cis-muconate.

The second coordinate block of enzymes comprises ß-carboxy-cis,cis-muconate-lactonizing enzyme and -carboxymuconolactone decarboxylase, which are uniquely associated with the protocatechuate pathway, and ß-ketoadipate enol-lactone hydrolase, which is functional in both the protocatechuate and the catechol pathways. This group of enzymes seems to be induced by ß-ketoadipate or ß-ketoadipyl coenzyme A.

Moraxella lwoffii, which degrades protocatechuate and catechol through identical step-reactions, regulates the synthesis of the enzymes mediating these conversions by a different mechanism.

CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

This article has been cited by other articles:

				E. Shimoni, T. Baasov, U. Ravid, and Y. Shoham The trans-Anethole Degradation Pathway in an Arthrobacter sp. J. Biol. Chem., March 29, 2002; 277(14): 11866 - 11872. [Abstract] [Full Text] [PDF]

				A. Tover, J. Zernant, S. A. Chugani, A. M. Chakrabarty, and M. Kivisaar Critical nucleotides in the interaction of CatR with the pheBA promoter: conservation of the CatR-mediated regulation mechanisms between the pheBA and catBCA operons Microbiology, January 1, 2000; 146(1): 173 - 183. [Abstract] [Full Text]

				F. Ampe, D. Léonard, and N. D. Lindley Repression of Phenol Catabolism by Organic Acids in Ralstonia eutropha Appl. Envir. Microbiol., January 1, 1998; 64(1): 1 - 6. [Abstract] [Full Text]

				D. T. Gilbson Microbial Degradation of Aromatic Compounds Science, September 13, 1968; 161(3846): 1093 - 1097. [PDF]

				J. L. Canovas, L. N. Ornston, and R. Y. Stanier Evolutionary Significance of Metabolic Control Systems Science, June 30, 1967; 156(3783): 1695 - 1699. [PDF]