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Desensitization of Regulatory Enzymes by a Metabolite of Plant Auxin

V. Tuli 1 and H. S. Moyed 1

From the 1 From the Department of Microbiology, University of Southern California School of Medicine, Los Angeles, California 90033

3-Methyleneoxindole, a metabolite in plants of the natural auxin, indole-3-acetic acid, has been found to desensitize several regulatory enzymes to feedback inhibition by their ultimate end products. As such effects could accelerate rate-limiting reactions, it has been suggested that increases in metabolism and growth by plant auxin may be the result of its enzymatic conversion to 3-methyleneoxindole.

Submitted on July 11, 1966


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