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Sodium-Potassium-activated Adenosine Triphosphatase of Electrophorus Electric Organ

III. AN ASSOCIATED POTASSIUM-ACTIVATED NEUTRAL PHOSPHATASE

From the ¹ From the Laboratory of Neurochemistry, National Institute of Neurological Diseases and Blindness, National Institutes of Health, Bethesda, Maryland 20014

A magnesium-potassium-activated hydrolysis of p-nitrophenyl phosphate is catalyzed by a microsomal preparation from Electrophorus electric organs. The properties of this reaction are compared with those of the magnesium-sodium-potassium-activated hydrolysis of adenosine triphosphate which is catalyzed by the same preparations. Although superficially similar, a detailed comparison of the alkali metal activation of the two reactions indicates that they are catalyzed by distinct enzymes.

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				G. inesi p-Nitrophenyl Phosphate Hydrolysis and Calcium Ion Transport in Fragmented Sarcoplasmic Reticulum Science, March 5, 1971; 171(3974): 901 - 903. [Abstract] [PDF]