HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Li, H.-C. Articles by Wright, L. D. Search for Related Content PubMed PubMed Citation Articles by Li, H.-C. Articles by Wright, L. D. Social Bookmarking                      What's this?

Conversion of Dethiobiotin to Biotin in Aspergillus niger

From the ¹ From the Graduate School of Nutrition and the Section of Biochemistry and Molecular Biology, Division of Biological Sciences, Cornell University, Ithaca, New York 14850

Investigation of the direct incorporation of ¹⁴C-carboxyl- and ¹⁴C-carbonyl-d-dethiobiotin both randomly labeled with ³H into biotin in Aspergillus niger has revealed the following.

The present results confirm our earlier evidence that ¹⁴C-carboxyl- and ¹⁴C-carbonyl-d-dethiobiotin is incorporated into biotin and show, moreover, that the dethiobiotin molecule is incorporated relatively intact into the biotin molecule, as the ratio ³H:¹⁴C remains nearly constant. The data provide some evidence that approximately 4 or more hydrogens must be abstracted from dethiobiotin in this over-all conversion.

CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

This article has been cited by other articles:

				D. B. McCormick A Trail of Research on Cofactors: An Odyssey with Friends J. Nutr., February 1, 2000; 130(2): 323 - 323. [Abstract] [Full Text]