HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Raghavan, S. Articles by Kanfer, J. N. Search for Related Content PubMed PubMed Citation Articles by Raghavan, S. Articles by Kanfer, J. N. Social Bookmarking                      What's this?

Ceramide Galactoside of Enriched Neuronal and Glial Fractions from Rat Brain

From the ¹ Eunice K. Shriver Center for Research in Mental Retardation, W. E. Fernald State School, 200 Trapelo Road, Waltham, Massachusetts 02154 and Neurology Research J. F. Kennedy Jr. Memorial Laboratories, Massachusetts General Hospital, Boston, Massachusetts, 02114

Fractions enriched in neuronal and glial cells from rat brain, as well as myelin isolated from the same brain samples, were analyzed for the composition of cholesterol, phospholipids, cerebrosides, and sulfatides. The fatty acid composition of ceramide galactoside of neurons, glia, and myelin showed significant differences. Less hydroxy fatty acids were recovered from ceramide galactoside obtained from neurons and glia when compared to ceramide galactoside from myelin. The nonhydroxy fatty acids of ceramide galactoside of the two cell types were mainly composed of palmitate and stearate while that of myelin contained longer chain homologs.

CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

This article has been cited by other articles:

				I. Zoller, M. Meixner, D. Hartmann, H. Bussow, R. Meyer, V. Gieselmann, and M. Eckhardt Absence of 2-Hydroxylated Sphingolipids Is Compatible with Normal Neural Development But Causes Late-Onset Axon and Myelin Sheath Degeneration J. Neurosci., September 24, 2008; 28(39): 9741 - 9754. [Abstract] [Full Text] [PDF]

				M. Eckhardt, K. K. Hedayati, J. Pitsch, R. Lullmann-Rauch, H. Beck, S. N. Fewou, and V. Gieselmann Sulfatide Storage in Neurons Causes Hyperexcitability and Axonal Degeneration in a Mouse Model of Metachromatic Leukodystrophy J. Neurosci., August 22, 2007; 27(34): 9009 - 9021. [Abstract] [Full Text] [PDF]