HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by McConkey, E. H. Articles by Hauber, E. J. Search for Related Content PubMed PubMed Citation Articles by McConkey, E. H. Articles by Hauber, E. J. Social Bookmarking                      What's this?

JBC, Vol. 250, Issue 4, 1311-1318, Feb, 1975

Evidence for heterogeneity of ribosomes within the HeLa cell

E. H. McConkey and E. J. Hauber

The proteins of several subsets of ribosomal subunits isolated from HeLa cells were separated by high resolution electrophoresis in polyacrylamide slab gels containing sodium dodecyl sulfate. Comparisons were made among native subunits, and subunits derived from single ribosomes, free polysomes, and membrane-bound polysomes. At least 10 heterogeneously distributed proteins were identified among the 40 S subunit proteins, compared wtih 17 to 20 proteins that occurred in all 40 S subunit classes. All 60 S subunits shared 34 separable proteins. One protein was missing only from membrane-bound 60 S subunits and another protein was present only in membrane-bound 60 S subunits. It is suggested that these two proteins regulate the binding of 60 S subunits to the endoplasmic reticulum.
CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?