JBC, Vol. 254, Issue 11, 4499-4501, Jun, 1979
Determination of cooperative interaction between clusters in Clostridium pasteurianum 2 (4Fe-4S) ferredoxin
W. V. Sweeney and B. A. McIntosh
The effect of reducing one 4Fe-4S cluster in Clostridium pasteurianum 2
(4Fe-4S) ferredoxin on the reduction potential of the unreduced cluster has
been investigated. While such an effect is suggested by both the x-ray
structure of Peptococcus aerogenes 2 (4F-4S) ferredoxin and the polypeptide
conformational change on reduction present in clostridial-type 2 (4Fe-4S)
ferredoxins, present studies indicate that cluster-cluster cooperative
interaction is not strong enough to be of functional importance in these
proteins.