HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Endemann, G. Articles by Brunengraber, H. Search for Related Content PubMed PubMed Citation Articles by Endemann, G. Articles by Brunengraber, H. Social Bookmarking                      What's this?

J. Biol. Chem., Vol. 255, Issue 23, 11091-11093, 12, 1980

The source of acetyl coenzyme A for acetylcholine synthesis in the perfused rat phrenic nerve-hemidiaphragm

G Endemann and H Brunengraber

Acetylcholine release by the phrenic nerve was measured in the isolated, perfused rat hemidiaphragm. In controls, the rate of release of acetylcholine increases with time; however, when (--)- hydroxycitrate, an inhibitor of ATP-citrate lyase, is added to the perfusate, the release of acetylcholine stabilizes at a level 40% below the final control value. In this preparation, the capacity of the citrate cleavage pathway to transfer acetyl coenzyme A from the nerve cell mitochondria to the cytosol increases with time; this is not the case for other transport processes.
CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

This article has been cited by other articles:

				A. P. Beigneux, C. Kosinski, B. Gavino, J. D. Horton, W. C. Skarnes, and S. G. Young ATP-Citrate Lyase Deficiency in the Mouse J. Biol. Chem., March 5, 2004; 279(10): 9557 - 9564. [Abstract] [Full Text] [PDF]