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J. Biol. Chem., Vol. 258, Issue 17, 10294-10295, 09, 1983

Preliminary X-ray crystallographic studies and molecular symmetry of the PII regulatory protein from Escherichia coli

SW Suh and SG Rhee

The PII regulatory protein (tetramer, Mr = 44,000) plays an important role in the regulation of glutamine synthetase in enteric bacteria. The unmodified form (PIIA) of the PII protein from Escherichia coli has been crystallized in the cubic space group I23. The unit cell dimension is a = 88.8 (+/-0.1) A, with six molecules in the unit cell (i.e. 1 subunit/asymmetric unit). The molecule has symmetry 222.
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E. R. Stadtman
The Story of Glutamine Synthetase Regulation
J. Biol. Chem., November 21, 2001; 276(48): 44357 - 44364.
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