HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Gasser, S. M. Articles by Schatz, G. Search for Related Content PubMed PubMed Citation Articles by Gasser, S. M. Articles by Schatz, G. Social Bookmarking                      What's this?

J. Biol. Chem., Vol. 258, Issue 6, 3427-3430, 03, 1983

Import of proteins into mitochondria. In vitro studies on the biogenesis of the outer membrane

SM Gasser and G Schatz

The yeast mitochondrial outer membrane contains a major 29-kilodalton protein which is encoded in the nucleus. When this polypeptide is synthesized in vitro and then incubated with isolated yeast mitochondria, it binds to the organelles and becomes resistant to externally added trypsin. Post-translational insertion of the 29- kilodalton protein in vitro is not accompanied by NH2-terminal processing, appears to require neither ATP nor a transmembrane electrochemical potential, and is also observed with purified outer membranes, but not with yeast microsomes. In vitro insertion of the 29- kilodalton polypeptide is thus in several respects different from that of polypeptides destined for the internal compartments of the mitochondrion.
CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

This article has been cited by other articles:

				F. Auchere, R. Santos, S. Planamente, E. Lesuisse, and J.-M. Camadro Glutathione-dependent redox status of frataxin-deficient cells in a yeast model of Friedreich's ataxia Hum. Mol. Genet., September 15, 2008; 17(18): 2790 - 2802. [Abstract] [Full Text] [PDF]

				X. X. Li and M. Colombini Catalyzed Insertion of Proteins into Phospholipid Membranes: Specificity of the Process Biophys. J., November 1, 2002; 83(5): 2550 - 2559. [Abstract] [Full Text] [PDF]

				X. Xu and M. Colombini Self-catalyzed Insertion of Proteins into Phospholipid Membranes J. Biol. Chem., September 27, 1996; 271(39): 23675 - 23682. [Abstract] [Full Text] [PDF]

				M. D. Smith, M. Petrak, P. D. Boucher, K. N. Barton, L. Carter, G. Reddy, E. Blachly-Dyson, M. Forte, J. Price, K. Verner, et al. Lysine Residues at Positions 234 and 236 in Yeast Porin Are Involved in Its Assembly into the Mitochondrial Outer Membrane J. Biol. Chem., November 24, 1995; 270(47): 28331 - 28336. [Abstract] [Full Text] [PDF]