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J. Biol. Chem., Vol. 262, Issue 14, 6443-6446, 05, 1987
RA Ignotz, T Endo and J Massague
Human platelet-derived transforming growth factor-beta (TGF-beta 1)
increases the accumulation of the extracellular matrix proteins,
fibronectin and type I collagen, in mesenchymal and epithelial cells. To
determine the basis for this effect, we have examined the levels of mRNAs
corresponding to fibronectin and alpha 2(I) procollagen in NRK-49 rat
fibroblasts and L6E9 rat myoblasts treated with TGF-beta 1. TGF- beta 1
increased severalfold the levels of mRNAs for both proteins. The kinetics
of this effect were similar for both mRNA species. The increase in
fibronectin and alpha 2(I) procollagen mRNAs was detectable 2 h after
addition of TGF-beta 1 to the cells and their maximal levels remained
constant for several days. Actinomycin D, but not cycloheximide, inhibited
the increase in fibronectin and alpha 2(I) procollagen mRNA levels induced
by TGF-beta 1. The results indicate that TGF-beta 1 controls the
composition and abundance of extracellular matrices at least in part by
inducing a coordinate increase in the levels of fibronectin and type I
collagen mRNAs.
Regulation of fibronectin and type I collagen mRNA levels by transforming growth factor-beta
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|
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|
|
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|
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|
 |
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