JBC

HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Jones, P. J.
Right arrow Articles by Prestegard, J. H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Jones, P. J.
Right arrow Articles by Prestegard, J. H.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?

J. Biol. Chem., Vol. 262, Issue 19, 8963-8965, Jul, 1987

[19F]-1H heteronuclear nuclear Overhauser effect studies of the acyl chain-binding site of acyl carrier protein

PJ Jones, EA Cioffi and JH Prestegard

[19F]-1H heteronuclear difference nuclear Overhauser effect experiments are performed on a sample of 5,5-difluorohexanoyl acyl carrier protein from Escherichia coli. Interaction of the fluorines at the 5-position of the acyl chain with protons on methyl groups of isoleucine 54 and alanine 59 is clearly indicated. The covalent attachment of the acyl chain via a prosthetic group to serine 36 and the known alpha-helix which exists from residues 36 to 51 greatly restrict the structural models which would allow acyl chain contact with residues 54 and 59.
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?


This article has been cited by other articles:


Home page
 J. Biol. Chem.Home page
N. R. De Lay and J. E. Cronan
In Vivo Functional Analyses of the Type II Acyl Carrier Proteins of Fatty Acid Biosynthesis
J. Biol. Chem., July 13, 2007; 282(28): 20319 - 20328.
[Abstract] [Full Text] [PDF]

Home page
 J BiochemHome page
S. J. Park, J.-S. Kim, W.-S. Son, and B. J. Lee
pH-Induced Conformational Transition of H. pylori Acyl Carrier Protein: Insight into the Unfolding of Local Structure
J. Biochem., March 1, 2004; 135(3): 337 - 346.
[Abstract] [Full Text] [PDF]

Home page
 Microbiol. Mol. Biol. Rev.Home page
P. Stanley, V. Koronakis, and C. Hughes
Acylation of Escherichia coli Hemolysin: A Unique Protein Lipidation Mechanism Underlying Toxin Function
Microbiol. Mol. Biol. Rev., June 1, 1998; 62(2): 309 - 333.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
A. S. Flaman, J. M. Chen, S. C. Van Iderstine, and D. M. Byers
Site-directed Mutagenesis of Acyl Carrier Protein (ACP) Reveals Amino Acid Residues Involved in ACP Structure and Acyl-ACP Synthetase Activity
J. Biol. Chem., September 14, 2001; 276(38): 35934 - 35939.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
 All ASBMB Journals   Molecular and Cellular Proteomics 
 Journal of Lipid Research   ASBMB Today 
Copyright © 1987 by the American Society for Biochemistry and Molecular Biology.