| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
J. Biol. Chem., Vol. 265, Issue 13, 7243-7247, 05, 1990
F Michon, M Beurret, A Gamian, JR Brisson and HJ Jennings
Three different oligosaccharides were isolated by mild acid hydrolysis of
the lipopolysaccharides, obtained from Neisseria meningitidis serotype 5,
and their structures were elucidated by combined chemical and physical
techniques. The use of 500-MHz 1H NMR in both one- dimensional and
two-dimensional modes as well as nuclear Overhauser effect experiments were
employed. To assist in the structural assignments the purified
oligosaccharides were also degraded by chemical and enzymatic procedures to
smaller fragments. The largest of the three original oligosaccharides is a
triantennary partially O- acetylated decasaccharide in which the largest
antenna terminates in a lacto-N-neotetraose unit. The smaller
oligosaccharides (heptasaccharide and octasaccharide) except for terminal
glycose deletions from the longest antenna are structural replicas of the
larger.
Structure of the L5 lipopolysaccharide core oligosaccharides of Neisseria meningitidis
Division of Biological Sciences, National Research Council of Canada, Ottawa, Ontario.
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
This article has been cited by other articles:
|
|
 |
|
  M. Harper, J. D. Boyce, A. D. Cox, F. St. Michael, I. W. Wilkie, P. J. Blackall, and B. Adler Pasteurella multocida Expresses Two Lipopolysaccharide Glycoforms Simultaneously, but Only a Single Form Is Required for Virulence: Identification of Two Acceptor-Specific Heptosyl I Transferases Infect. Immun., August 1, 2007; 75(8): 3885 - 3893. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. M. Kahler, S. Lyons-Schindler, B. Choudhury, J. Glushka, R. W. Carlson, and D. S. Stephens O-Acetylation of the Terminal N-Acetylglucosamine of the Lipooligosaccharide Inner Core in Neisseria meningitidis: INFLUENCE ON INNER CORE STRUCTURE AND ASSEMBLY J. Biol. Chem., July 21, 2006; 281(29): 19939 - 19948. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. M. Kahler, A. Datta, Y.-l. Tzeng, R. W. Carlson, and D. S. Stephens Inner core assembly and structure of the lipooligosaccharide of Neisseria meningitidis: capacity of strain NMB to express all known immunotype epitopes Glycobiology, April 1, 2005; 15(4): 409 - 419. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. C. Wright, D. W. Hood, G. A. Randle, K. Makepeace, A. D. Cox, J. Li, R. Chalmers, J. C. Richards, and E. R. Moxon lpt6, a Gene Required for Addition of Phosphoethanolamine to Inner-Core Lipopolysaccharide of Neisseria meningitidis and Haemophilus influenzae J. Bacteriol., October 15, 2004; 186(20): 6970 - 6982. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y.-L. Tzeng, A. Datta, K. Ambrose, M. Lo, J. K. Davies, R. W. Carlson, D. S. Stephens, and C. M. Kahler The MisR/MisS Two-component Regulatory System Influences Inner Core Structure and Immunotype of Lipooligosaccharide in Neisseria meningitidis J. Biol. Chem., August 13, 2004; 279(33): 35053 - 35062. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. A. J. Gidney, J. S. Plested, S. Lacelle, P. A. Coull, J. C. Wright, K. Makepeace, J.-R. Brisson, A. D. Cox, E. R. Moxon, and J. C. Richards Development, Characterization, and Functional Activity of a Panel of Specific Monoclonal Antibodies to Inner Core Lipopolysaccharide Epitopes in Neisseria meningitidis Infect. Immun., January 1, 2004; 72(1): 559 - 569. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. D. Cox, J. C. Wright, J. Li, D. W. Hood, E. R. Moxon, and J. C. Richards Phosphorylation of the Lipid A Region of Meningococcal Lipopolysaccharide: Identification of a Family of Transferases That Add Phosphoethanolamine to Lipopolysaccharide J. Bacteriol., June 1, 2003; 185(11): 3270 - 3277. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. R. Andersen, T. Guthrie, G. R. Guile, J. Kolberg, S. Hou, L. Hyland, and S. Y. C. Wong Cross-Reactive Polyclonal Antibodies to the Inner Core of Lipopolysaccharide from Neisseria meningitidis Infect. Immun., March 1, 2002; 70(3): 1293 - 1300. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. Brandtzaeg, A. Bjerre, R. Ovstebo, B. Brusletto, G. B. Joo, and P. Kierulf Invited review: Neisseria meningitidis lipopolysaccharides in human pathology Innate Immunity, December 1, 2001; 7(6): 401 - 420. [Abstract] [PDF]
|
|
|
|
|
|
D. Arking, Y. Tong, and D. C. Stein Analysis of Lipooligosaccharide Biosynthesis in the Neisseriaceae J. Bacteriol., February 1, 2001; 183(3): 934 - 941. [Abstract] [Full Text]
|
|
|
|
|
|
Y. Tong, V. Reinhold, B. Reinhold, B. Brandt, and D. C. Stein Structural and Immunochemical Characterization of the Lipooligosaccharides Expressed by Neisseria subflava 44 J. Bacteriol., February 1, 2001; 183(3): 942 - 950. [Abstract] [Full Text]
|
|
|
|
|
|
J. M. Griffiss, B. L. Brandt, N. B. Saunders, and W. Zollinger Structural Relationships and Sialylation among Meningococcal L1, L8, and L3,7 Lipooligosaccharide Serotypes J. Biol. Chem., March 24, 2000; 275(13): 9716 - 9724. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B. M. Charalambous, J. Evans, I. M. Feavers, and M. C. J. Maiden Comparative Analysis of Two Meningococcal Immunotyping Monoclonal Antibodies by Resonant Mirror Biosensor and Antibody Gene Sequencing Clin. Vaccine Immunol., November 1, 1999; 6(6): 838 - 843. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. S. Plested, K. Makepeace, M. P. Jennings, M. A. J. Gidney, S. Lacelle, J.-R. Brisson, A. D. Cox, A. Martin, A. G. Bird, C. M. Tang, et al. Conservation and Accessibility of an Inner Core Lipopolysaccharide Epitope of Neisseria meningitidis Infect. Immun., October 1, 1999; 67(10): 5417 - 5426. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
W. Wakarchuk, A. Martin, M. P. Jennings, E. R. Moxon, and J. C. Richards Functional Relationships of the Genetic Locus Encoding the Glycosyltransferase Enzymes Involved in Expression of the Lacto-N-neotetraose Terminal Lipopolysaccharide Structure in Neisseria meningitidis J. Biol. Chem., August 9, 1996; 271(32): 19166 - 19173. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| All ASBMB Journals | Molecular and Cellular Proteomics |
| Journal of Lipid Research | ASBMB Today |
