JBC Origene Your Gene Company

HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Janssen, G. M.
Right arrow Articles by Moller, W.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Janssen, G. M.
Right arrow Articles by Moller, W.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?

J. Biol. Chem., Vol. 266, Issue 23, 14885-14888, Aug, 1991

A major substrate of maturation promoting factor identified as elongation factor 1 beta gamma delta in Xenopus laevis

GM Janssen, J Morales, A Schipper, JC Labbe, O Mulner-Lorillon, R Belle and W Moller
Department of Medical Biochemistry, Sylvius Laboratory, State University of Leiden, The Netherlands.

Protein synthesis is believed to be under control of the cell cycle during meiosis and mitosis. Any relationship between substrates for cdc2 kinase and components of the protein synthetic apparatus would therefore be of prime importance. During meiosis of Xenopus laevis oocytes one of the substrates for this kinase is a p47 protein, which is complexed to two other proteins, P36 and P30. Judged from partial amino acid sequence data on P47 and P30, the P30 and P47 proteins were reported to resemble the protein synthetic elongation factors (EF) 1 beta and 1 gamma from Artemia salina (Belle, R., Derancourt, J., Poulhe, R., Capony, J.P., Ozon, R., and Mulner-Lorillon, O. (1989) FEBS Lett. 255, 101-104). This paper shows that the complex composed of P30, P47, and P36 from Xenopus is identical to the complex of EF-1 beta, EF- 1 gamma, and EF-1 delta from Artemia according to two criteria. 1) Both stimulate elongation factor 1 alpha-mediated transfer RNA binding to ribosomes and exchange of guanine nucleotides on elongation factor 1 alpha to a comparable degree. 2) Each of the three subunits of the protein complex P30.P47.P36 from Xenopus shows a structural homology with one of the corresponding subunits of EF-1 beta gamma delta from Artemia. Presumably the phosphorylation of EF-1 gamma, which associates with tubulin at least in vitro, is important in processes following the onset of meiosis which is accompanied by a rise of protein synthesis.
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?


This article has been cited by other articles:


Home page
 Mol. Cell. Biol.Home page
G. Sivan, N. Kedersha, and O. Elroy-Stein
Ribosomal Slowdown Mediates Translational Arrest during Cellular Division
Mol. Cell. Biol., October 1, 2007; 27(19): 6639 - 6646.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
M. G. Jeppesen, P. Ortiz, W. Shepard, T. G. Kinzy, J. Nyborg, and G. R. Andersen
The Crystal Structure of the Glutathione S-Transferase-like Domain of Elongation Factor 1B{gamma} from Saccharomyces cerevisiae
J. Biol. Chem., November 21, 2003; 278(47): 47190 - 47198.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
S. Vanwetswinkel, J. Kriek, G. R. Andersen, P. Guntert, J. Dijk, G. W. Canters, and G. Siegal
Solution Structure of the 162 Residue C-terminal Domain of Human Elongation Factor 1B{gamma}
J. Biol. Chem., October 31, 2003; 278(44): 43443 - 43451.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
L.-L. Ong, C. P. N. Er, A. Ho, M. T. Aung, and H. Yu
Kinectin Anchors the Translation Elongation Factor-1{delta} to the Endoplasmic Reticulum
J. Biol. Chem., August 22, 2003; 278(34): 32115 - 32123.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
M. Al-Maghrebi, H. Brule, M. Padkina, C. Allen, W. M. Holmes, and Z. E. Zehner
The 3' untranslated region of human vimentin mRNA interacts with protein complexes containing eEF-1{gamma} and HAX-1
Nucleic Acids Res., December 1, 2002; 30(23): 5017 - 5028.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
A. Monnier, R. Belle, J. Morales, P. Cormier, S. Boulben, and O. Mulner-Lorillon
Evidence for regulation of protein synthesis at the elongation step by CDK1/cyclin B phosphorylation
Nucleic Acids Res., April 1, 2001; 29(7): 1453 - 1457.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
G.-T. Sheu and J. A. Traugh
Recombinant Subunits of Mammalian Elongation Factor 1 Expressed in Escherichia coli. SUBUNIT INTERACTIONS, ELONGATION ACTIVITY, AND PHOSPHORYLATION BY PROTEIN KINASE CKII
J. Biol. Chem., December 26, 1997; 272(52): 33290 - 33297.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
Y.-W. E. Chang and J. A. Traugh
Phosphorylation of Elongation Factor 1 and Ribosomal Protein S6 by Multipotential S6 Kinase and Insulin Stimulation of Translational Elongation
J. Biol. Chem., November 7, 1997; 272(45): 28252 - 28257.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
 All ASBMB Journals   Molecular and Cellular Proteomics 
 Journal of Lipid Research   ASBMB Today 
Copyright © 1991 by the American Society for Biochemistry and Molecular Biology.