HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Wray, J. W. Articles by Abeles, R. H. Search for Related Content PubMed PubMed Citation Articles by Wray, J. W. Articles by Abeles, R. H. Social Bookmarking                      What's this?

J. Biol. Chem., Vol. 268, Issue 29, 21466-21469, 10, 1993

A bacterial enzyme that catalyzes formation of carbon monoxide

JW Wray and RH Abeles
Graduate Department of Biochemistry, Brandeis University, Waltham, Massachusetts 02254.

We have isolated and purified an enzyme (E-2) from Klebsiella pneumoniae, which catalyzes the formation of CO from CH3-S-CH2-CH2-CO- C(OH) = CH-O- (III). This compound is an intermediate in the conversion of 5'-methylthioadenosine to methionine. Concomitant with CO formation, methylthiopropionic acid and formate are produced and O2 is consumed. E- 2 also catalyzes the formation of CO, formate, and butyrate from CH3- CH2-CH2-CO-C(OH) = CH-O- (IIIa), the desthio analog of III. Experiments with isotopic IIIa have shown that formate is derived from 1-C, and CO from 2-C. E-2 has a M(r) = 18,500 and requires Mg2+, and no chromophoric cofactor has been detected.
CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

This article has been cited by other articles:

				J. H. Kim, H. S. Kim, Y. H. Lee, Y. S. Kim, H. W. Oh, H. Joung, S. K. Chae, K. H. Suh, and J. H. Jeon Polyamine Biosynthesis Regulated by StARD Expression Plays an Important Role in Potato Wound Periderm Formation Plant Cell Physiol., October 1, 2008; 49(10): 1627 - 1632. [Abstract] [Full Text] [PDF]

				H. Ashida, Y. Saito, T. Nakano, N. Tandeau de Marsac, A. Sekowska, A. Danchin, and A. Yokota RuBisCO-like proteins as the enolase enzyme in the methionine salvage pathway: functional and evolutionary relationships between RuBisCO-like proteins and photosynthetic RuBisCO J. Exp. Bot., May 1, 2008; 59(7): 1543 - 1554. [Abstract] [Full Text] [PDF]

				S. Oram, F. Jiang, X. Cai, R. Haleem, Z. Dincer, and Z. Wang Identification and Characterization of an Androgen-Responsive Gene Encoding an Aci-Reductone Dioxygenase-Like Protein in the Rat Prostate Endocrinology, April 1, 2004; 145(4): 1933 - 1942. [Abstract] [Full Text] [PDF]

				T. Uekita, I. Gotoh, T. Kinoshita, Y. Itoh, H. Sato, T. Shiomi, Y. Okada, and M. Seiki Membrane-type 1 Matrix Metalloproteinase Cytoplasmic Tail-binding Protein-1 Is a New Member of the Cupin Superfamily: A POSSIBLE MULTIFUNCTIONAL PROTEIN ACTING AS AN INVASION SUPPRESSOR DOWN-REGULATED IN TUMORS J. Biol. Chem., March 26, 2004; 279(13): 12734 - 12743. [Abstract] [Full Text] [PDF]

				L. C. Berger, J. Wilson, P. Wood, and B. J. Berger Methionine Regeneration and Aspartate Aminotransferase in Parasitic Protozoa J. Bacteriol., August 1, 2001; 183(15): 4421 - 4434. [Abstract] [Full Text] [PDF]

				T. A. Seiflein and J. G. Lawrence Methionine-to-Cysteine Recycling in Klebsiella aerogenes J. Bacteriol., January 1, 2001; 183(1): 336 - 346. [Abstract] [Full Text]

				J. Heilbronn, J. Wilson, and B. J. Berger Tyrosine Aminotransferase Catalyzes the Final Step of Methionine Recycling in Klebsiella pneumoniae J. Bacteriol., March 15, 1999; 181(6): 1739 - 1747. [Abstract] [Full Text]

				Y. Dai, P. C. Wensink, and R. H. Abeles One Protein, Two Enzymes J. Biol. Chem., January 15, 1999; 274(3): 1193 - 1195. [Abstract] [Full Text] [PDF]

				J. W. Wray and R. H. Abeles The Methionine Salvage Pathway in Klebsiella pneumoniae and Rat Liver J. Biol. Chem., February 17, 1995; 270(7): 3147 - 3153. [Abstract] [Full Text] [PDF]