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Volume 270, Number 3, Issue of January 20, 1995 pp. 1113-1122
©1995 by The American Society for Biochemistry and Molecular Biology, Inc.
Existence of Branched Side Chains in the Cell Wall Mannan of Pathogenic Yeast, Candida albicans
STRUCTURE-ANTIGENICITY RELATIONSHIP BETWEEN THE CELL WALL MANNANS OF CANDIDA ALBICANS AND CANDIDA PARAPSILOSIS

(Received for publication, July 11, 1994; and in revised form, November 9, 1994)

Nobuyuki Shibata ,  Kyoko Ikuta ,  Tomonori Imai ,  Yohko Satoh ,  Richi Satoh ,  Atsuko Suzuki ,  Chizuko Kojima ,  Hidemitsu Kobayashi ,  Kanehiko Hisamichi ,  Shigeo Suzuki

Isolation of side chain oligosaccharides from mannans of Candida albicans NIH B-792 (serotype B) and Candida parapsilosis IFO 1396 strains has been conducted by acetolysis under mild conditions. Structural study of these oligosaccharides by ^1H and C NMR and methylation analyses indicated the presence of novel branched side chains with the following structures in C. albicans mannan.



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