Advertisement
JBC

HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Submit a Letter to Editor
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowRequest Permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Holz,, G. G.
Right arrow Articles by Habener, J. F.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Holz,, G. G., IV
Right arrow Articles by Habener, J. F.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?

Volume 270, Number 30, Issue of July 28, pp. 17749-17757, 1995
©1995 by The American Society for Biochemistry and Molecular Biology, Inc.
Activation of a cAMP-regulated Ca2+-Signaling Pathway in Pancreatic -Cells by the Insulinotropic Hormone Glucagon-like Peptide-1 (*)

(Received for publication, November 1, 1994; and in revised form, March 27, 1995)

George G. Holz , IV (1)(§),  Colin A. Leech ,  Joel F. Habener (¶)

From the Laboratory of Molecular Endocrinology, Howard Hughes Medical Institute, Diabetes Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114

This abstract is not available online.



Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?


This article has been cited by other articles:


Home page
 Pharmacol. Rev.Home page
W. Kim and J. M. Egan
The Role of Incretins in Glucose Homeostasis and Diabetes Treatment
Pharmacol. Rev., December 1, 2008; 60(4): 470 - 512.
[Abstract] [Full Text] [PDF]

Home page
 JGPHome page
L. S. Ramos, J. H. Zippin, M. Kamenetsky, J. Buck, and L. R. Levin
Glucose and GLP-1 Stimulate cAMP Production via Distinct Adenylyl Cyclases in INS-1E Insulinoma Cells
J. Gen. Physiol., August 25, 2008; 132(3): 329 - 338.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
Y. Suzuki, H. Zhang, N. Saito, I. Kojima, T. Urano, and H. Mogami
Glucagon-like Peptide 1 Activates Protein Kinase C through Ca2+-dependent Activation of Phospholipase C in Insulin-secreting Cells
J. Biol. Chem., September 29, 2006; 281(39): 28499 - 28507.
[Abstract] [Full Text] [PDF]

Home page
 J. Pharmacol. Exp. Ther.Home page
G. Liu, S. M. P. Jacobo, N. Hilliard, and G. H. Hockerman
Differential Modulation of Cav1.2 and Cav1.3-Mediated Glucose-Stimulated Insulin Secretion by cAMP in INS-1 Cells: Distinct Roles for Exchange Protein Directly Activated by cAMP 2 (Epac2) and Protein Kinase A
J. Pharmacol. Exp. Ther., July 1, 2006; 318(1): 152 - 160.
[Abstract] [Full Text] [PDF]

Home page
 J. Physiol.Home page
G. Kang, O. G. Chepurny, B. Malester, M. J. Rindler, H. Rehmann, J. L. Bos, F. Schwede, W. A. Coetzee, and G. G. Holz
cAMP sensor Epac as a determinant of ATP-sensitive potassium channel activity in human pancreatic {beta} cells and rat INS-1 cells
J. Physiol., June 15, 2006; 573(3): 595 - 609.
[Abstract] [Full Text] [PDF]

Home page
 DiabetesHome page
D. Liu, W. Zhen, Z. Yang, J. D. Carter, H. Si, and K. A. Reynolds
Genistein Acutely Stimulates Insulin Secretion in Pancreatic {beta}-Cells Through a cAMP-Dependent Protein Kinase Pathway.
Diabetes, April 1, 2006; 55(4): 1043 - 1050.
[Abstract] [Full Text] [PDF]

Home page
 PhysiologyHome page
E. M Sinclair and D. J. Drucker
Proglucagon-Derived Peptides: Mechanisms of Action and Therapeutic Potential
Physiology, October 1, 2005; 20(5): 357 - 365.
[Abstract] [Full Text] [PDF]

Home page
 Physiol. Rev.Home page
N. Wettschureck and S. Offermanns
Mammalian G Proteins and Their Cell Type Specific Functions
Physiol Rev, October 1, 2005; 85(4): 1159 - 1204.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
J. Storling, S. V. Zaitsev, I. L. Kapelioukh, A. E. Karlsen, N. Billestrup, P.-O. Berggren, and T. Mandrup-Poulsen
Calcium Has a Permissive Role in Interleukin-1{beta}-Induced c-Jun N-Terminal Kinase Activation in Insulin-Secreting Cells
Endocrinology, July 1, 2005; 146(7): 3026 - 3036.
[Abstract] [Full Text] [PDF]

Home page
 J. Physiol.Home page
G. Kang, O. G Chepurny, M. J Rindler, L. Collis, Z. Chepurny, W.-h. Li, M. Harbeck, M. W Roe, and G. G Holz
A cAMP and Ca2+ coincidence detector in support of Ca2+-induced Ca2+ release in mouse pancreatic {beta} cells
J. Physiol., July 1, 2005; 566(1): 173 - 188.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Endocrinol.Home page
K. Masur, E. C. Tibaduiza, C. Chen, B. Ligon, and M. Beinborn
Basal Receptor Activation by Locally Produced Glucagon-Like Peptide-1 Contributes to Maintaining {beta}-Cell Function
Mol. Endocrinol., May 1, 2005; 19(5): 1373 - 1382.
[Abstract] [Full Text] [PDF]

Home page
 DiabetesHome page
A. K. Bose, M. M. Mocanu, R. D. Carr, C. L. Brand, and D. M. Yellon
Glucagon-like Peptide 1 Can Directly Protect the Heart Against Ischemia/Reperfusion Injury
Diabetes, January 1, 2005; 54(1): 146 - 151.
[Abstract] [Full Text] [PDF]

Home page
 DiabetesHome page
G. Kwon, C. A. Marshall, K. L. Pappan, M. S. Remedi, and M. L. McDaniel
Signaling Elements Involved in the Metabolic Regulation of mTOR by Nutrients, Incretins, and Growth Factors in Islets
Diabetes, December 1, 2004; 53(suppl_3): S225 - S232.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
G. Kwon, K. L. Pappan, C. A. Marshall, J. E. Schaffer, and M. L. McDaniel
cAMP Dose-dependently Prevents Palmitate-induced Apoptosis by Both Protein Kinase A- and cAMP-Guanine Nucleotide Exchange Factor-dependent Pathways in {beta}-Cells
J. Biol. Chem., March 5, 2004; 279(10): 8938 - 8945.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Endocrinol. Metab.Home page
Y. Miura and H. Matsui
Glucagon-like peptide-1 induces a cAMP-dependent increase of [Na+]i associated with insulin secretion in pancreatic {beta}-cells
Am J Physiol Endocrinol Metab, November 1, 2003; 285(5): E1001 - E1009.
[Abstract] [Full Text] [PDF]

Home page
 Pharmacol. Rev.Home page
K. E. Mayo, L. J. Miller, D. Bataille, S. Dalle, B. Goke, B. Thorens, and D. J. Drucker
International Union of Pharmacology. XXXV. The Glucagon Receptor Family
Pharmacol. Rev., March 1, 2003; 55(1): 167 - 194.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
E. Gomez, C. Pritchard, and T. P. Herbert
cAMP-dependent Protein Kinase and Ca2+ Influx through L-type Voltage-gated Calcium Channels Mediate Raf-independent Activation of Extracellular Regulated Kinase in Response to Glucagon-like Peptide-1 in Pancreatic beta -Cells
J. Biol. Chem., December 6, 2002; 277(50): 48146 - 48151.
[Abstract] [Full Text] [PDF]

Home page
 DiabetesHome page
P. E. MacDonald, W. El-kholy, M. J. Riedel, A. M. F. Salapatek, P. E. Light, and M. B. Wheeler
The Multiple Actions of GLP-1 on the Process of Glucose-Stimulated Insulin Secretion
Diabetes, December 1, 2002; 51(90003): S434 - 442.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
S. Yamada, M. Komatsu, Y. Sato, K. Yamauchi, I. Kojima, T. Aizawa, and K. Hashizume
Time-Dependent Stimulation of Insulin Exocytosis by 3',5'-Cyclic Adenosine Monophosphate in the Rat Islet {beta}-Cell
Endocrinology, November 1, 2002; 143(11): 4203 - 4209.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
L. Farilla, H. Hui, C. Bertolotto, E. Kang, A. Bulotta, U. Di Mario, and R. Perfetti
Glucagon-Like Peptide-1 Promotes Islet Cell Growth and Inhibits Apoptosis in Zucker Diabetic Rats
Endocrinology, November 1, 2002; 143(11): 4397 - 4408.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Endocrinol.Home page
P. E. Light, J. E. Manning Fox, M. J. Riedel, and M. B. Wheeler
Glucagon-Like Peptide-1 Inhibits Pancreatic ATP-Sensitive Potassium Channels via a Protein Kinase A- and ADP-Dependent Mechanism
Mol. Endocrinol., September 1, 2002; 16(9): 2135 - 2144.
[Abstract] [Full Text] [PDF]

Home page
 DiabetesHome page
M. C. Lawrence, H. S. Bhatt, and R. A. Easom
NFAT Regulates Insulin Gene Promoter Activity in Response to Synergistic Pathways Induced by Glucose and Glucagon-Like Peptide-1
Diabetes, March 1, 2002; 51(3): 691 - 698.
[Abstract] [Full Text] [PDF]

Home page
 DiabetesHome page
F. Qian, P. Huang, L. Ma, A. Kuznetsov, N. Tamarina, and L. H. Philipson
TRP Genes: Candidates for Nonselective Cation Channels and Store-Operated Channels in Insulin-Secreting Cells
Diabetes, February 1, 2002; 51(90001): S183 - 189.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
D. M. Kemp and J. F. Habener
Insulinotropic Hormone Glucagon-Like Peptide 1 (GLP-1) Activation of Insulin Gene Promoter Inhibited by p38 Mitogen-Activated Protein Kinase
Endocrinology, March 1, 2001; 142(3): 1179 - 1187.
[Abstract] [Full Text] [PDF]

Home page
 J. Pharmacol. Exp. Ther.Home page
S. Hashiguchi, T. Yada, and T. Arima
A New Hypoglycemic Agent, JTT-608, Evokes Protein Kinase A-Mediated Ca2+ Signaling in Rat Islet {beta}-Cells: Strict Regulation by Glucose, Link to Insulin Release, and Cooperation with Glucagon-Like Peptide-1(7-36)amide and Pituitary Adenylate Cyclase-Activating Polypeptide
J. Pharmacol. Exp. Ther., January 1, 2001; 296(1): 22 - 30.
[Abstract] [Full Text]

Home page
 Am. J. Physiol. Endocrinol. Metab.Home page
M. Srinivasan, R. Aalinkeel, F. Song, B. Lee, S. G. Laychock, and M. S. Patel
Adaptive changes in insulin secretion by islets from neonatal rats raised on a high-carbohydrate formula
Am J Physiol Endocrinol Metab, December 1, 2000; 279(6): E1347 - E1357.
[Abstract] [Full Text] [PDF]

Home page
 Integr. Comp. Biol.Home page
T. P. Mommsen
Glucagon-like Peptide-1 in Fishes: The Liver and Beyond
Integr. Comp. Biol., April 1, 2000; 40(2): 259 - 268.
[Abstract] [Full Text] [PDF]

Home page
 Endocr. Rev.Home page
T. J. Kieffer and J. Francis Habener
The Glucagon-Like Peptides
Endocr. Rev., December 1, 1999; 20(6): 876 - 913.
[Abstract] [Full Text]

Home page
 EndocrinologyHome page
H.-P. Bode, B. Moormann, R. Dabew, and B. Göke
Glucagon-Like Peptide 1 Elevates Cytosolic Calcium in Pancreatic {beta}-Cells Independently of Protein Kinase A
Endocrinology, September 1, 1999; 140(9): 3919 - 3927.
[Abstract] [Full Text]

Home page
 J. Biol. Chem.Home page
P. Han, J. Werber, M. Surana, N. Fleischer, and T. Michaeli
The Calcium/Calmodulin-dependent Phosphodiesterase PDE1C Down-regulates Glucose-induced Insulin Secretion
J. Biol. Chem., August 6, 1999; 274(32): 22337 - 22344.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
G. G. Holz, C. A. Leech, R. S. Heller, M. Castonguay, and J. F. Habener
cAMP-dependent Mobilization of Intracellular Ca2+ Stores by Activation of Ryanodine Receptors in Pancreatic beta -Cells. A Ca2+ SIGNALING SYSTEM STIMULATED BY THE INSULINOTROPIC HORMONE GLUCAGON-LIKE PEPTIDE-1-(7-37)
J. Biol. Chem., May 14, 1999; 274(20): 14147 - 14156.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
C. Montrose-Rafizadeh, P. Avdonin, M. J. Garant, B. D. Rodgers, S. Kole, H. Yang, M. A. Levine, W. Schwindinger, and M. Bernier
Pancreatic Glucagon-Like Peptide-1 Receptor Couples to Multiple G Proteins and Activates Mitogen-Activated Protein Kinase Pathways in Chinese Hamster Ovary Cells
Endocrinology, March 1, 1999; 140(3): 1132 - 1140.
[Abstract] [Full Text]

Home page
 EndocrinologyHome page
E. Grapengiesser
Unmasking of a Periodic Na+ Entry into Glucose-Stimulated Pancreatic {beta}-Cells after Partial Inhibition of the Na/K Pump
Endocrinology, July 1, 1998; 139(7): 3227 - 3231.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Cell Physiol.Home page
L. H. Hansen, J. Gromada, P. Bouchelouche, T. Whitmore, L. Jelinek, W. Kindsvogel, and E. Nishimura
Glucagon-mediated Ca2+ signaling in BHK cells expressing cloned human glucagon receptors
Am J Physiol Cell Physiol, June 1, 1998; 274(6): C1552 - C1562.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
M. W. Roe, J. F. Worley III, F. Qian, N. Tamarina, A. A. Mittal, F. Dralyuk, N. T. Blair, R. J. Mertz, L. H. Philipson, and I. D. Dukes
Characterization of a Ca2+ Release-activated Nonselective Cation Current Regulating Membrane Potential and [Ca2+]i Oscillations in Transgenically Derived beta -Cells
J. Biol. Chem., April 24, 1998; 273(17): 10402 - 10410.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Cell Physiol.Home page
K. Yaekura and T. Yada
[Ca2+]i-reducing action of cAMP in rat pancreatic beta -cells: involvement of thapsigargin-sensitive stores
Am J Physiol Cell Physiol, February 1, 1998; 274(2): C513 - C521.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
C. A. Leech and J. F. Habener
Insulinotropic Glucagon-like Peptide-1-mediated Activation of Non-selective Cation Currents in Insulinoma Cells Is Mimicked by Maitotoxin
J. Biol. Chem., July 18, 1997; 272(29): 17987 - 17993.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
S. Khoo and M. H. Cobb
Activation of mitogen-activating protein kinase by glucose is not required for insulin secretion
PNAS, May 27, 1997; 94(11): 5599 - 5604.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
A. Z. Zhao, H. Zhao, J. Teague, W. Fujimoto, and J. A. Beavo
Attenuation of insulin secretion by insulin-like growth factor 1 is mediated through activation of phosphodiesterase 3B
PNAS, April 1, 1997; 94(7): 3223 - 3228.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
S. G. Straub, B. Kornreich, R. E. Oswald, E. F. Nemeth, and G. W. G. Sharp
The Calcimimetic R-467 Potentiates Insulin Secretion in Pancreatic beta Cells by Activation of a Nonspecific Cation Channel
J. Biol. Chem., June 16, 2000; 275(25): 18777 - 18784.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
C. Wasmeier and J. C. Hutton
Secretagogue-dependent Phosphorylation of the Insulin Granule Membrane Protein Phogrin Is Mediated by cAMP-dependent Protein Kinase
J. Biol. Chem., August 17, 2001; 276(34): 31919 - 31928.
[Abstract] [Full Text] [PDF]

Home page
 Circ. Res.Home page
M. G. Vila Petroff, J. M. Egan, X. Wang, and S. J. Sollott
Glucagon-Like Peptide-1 Increases cAMP but Fails to Augment Contraction in Adult Rat Cardiac Myocytes
Circ. Res., August 31, 2001; 89(5): 445 - 452.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
 All ASBMB Journals   Molecular and Cellular Proteomics 
 Journal of Lipid Research   ASBMB Today 
Copyright © 1995 by the American Society for Biochemistry and Molecular Biology.
Advertisement
spacer
Advertisement
Advertisement