|
Volume 270,
Number 33,
Issue of August 18, pp. 19495-19500, 1995
©1995 by The American Society for Biochemistry and Molecular Biology, Inc.
Molecular
Cloning and Functional Expression of a Novel CC Chemokine Receptor cDNA
from a Human Basophilic Cell Line
(Received for publication, May 5, 1995; and in revised form, May 15, 1995)
Christine A.
Power ,
Alexandra
Meyer,
Karin
Nemeth ,
Kevin B.
Bacon ,
Arlene
J.
Hoogewerf,
Amanda E. I.
Proudfoot,
Timothy
N. C.
Wells
We report the cloning and characterization of a novel basophil
CC chemokine receptor, K5-5, from the human immature basophilic
cell line KU-812. The predicted protein sequence of K5-5 shows
only 49% identity to the macrophage inflammatory protein-1 /RANTES
receptor (CC CKR-1) and 47% identity to monocyte chemotactic protein-1
receptor (b form), suggesting that this cDNA encodes a novel member of
the CC chemokine receptor family. Analysis of K5-5 mRNA
expression indicates that it is restricted to leukocyte-rich tissues.
In addition, we have shown significant levels of K5-5 mRNA in
human basophils, which were up-regulated by treatment with
interleukin-5. The CC chemokines, macrophage inflammatory
protein-1 , RANTES, and monocyte chemotactic protein-1 were able to
stimulate a Ca -activated chloride channel in Xenopus laevis oocytes injected with K5-5 cRNA, whereas
no signal was detected in response to monocyte chemotactic protein-2,
macrophage inflammatory protein-1 , or the CXC chemokine,
interleukin-8. Taken together, these results indicate for the first
time the presence of a CC chemokine receptor on basophils, which
functions as a ``shared'' CC chemokine receptor and may
therefore be implicated in the pathogenesis of basophil-mediated
allergic diseases.

CiteULike Complore Connotea Del.icio.us Digg Reddit Technorati What's this?
This article has been cited by other articles:

|
 |

|
 |
 
A. W. Mailloux and M. R. I. Young
NK-Dependent Increases in CCL22 Secretion Selectively Recruits Regulatory T Cells to the Tumor Microenvironment
J. Immunol.,
March 1, 2009;
182(5):
2753 - 2765.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
R. S. Y. Wong, V. Bodart, M. Metz, J. Labrecque, G. Bridger, and S. P. Fricker
Comparison of the Potential Multiple Binding Modes of Bicyclam, Monocylam, and Noncyclam Small-Molecule CXC Chemokine Receptor 4 Inhibitors
Mol. Pharmacol.,
December 1, 2008;
74(6):
1485 - 1495.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
T. Traeger, W. Kessler, V. Assfalg, K. Cziupka, P. Koerner, C. Dassow, K. Breitbach, M. Mikulcak, I. Steinmetz, K. Pfeffer, et al.
Detrimental Role of CC Chemokine Receptor 4 in Murine Polymicrobial Sepsis
Infect. Immun.,
November 1, 2008;
76(11):
5285 - 5293.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
I. A. Khasabova, C. L. Stucky, C. Harding-Rose, L. Eikmeier, A. J. Beitz, L. G. Coicou, A. E. Hanson, D. A. Simone, and V. S. Seybold
Chemical Interactions between Fibrosarcoma Cancer Cells and Sensory Neurons Contribute to Cancer Pain
J. Neurosci.,
September 19, 2007;
27(38):
10289 - 10298.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
C. E. Brown, R. P. Vishwanath, B. Aguilar, R. Starr, J. Najbauer, K. S. Aboody, and M. C. Jensen
Tumor-Derived Chemokine MCP-1/CCL2 Is Sufficient for Mediating Tumor Tropism of Adoptively Transferred T Cells
J. Immunol.,
September 1, 2007;
179(5):
3332 - 3341.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
N. F. Pinheiro Jr., M. D. R. Hermida, M. P. Macedo, J. Mengel, A. Bafica, and W. L. C. dos-Santos
Leishmania Infection Impairs {beta}1-Integrin Function and Chemokine Receptor Expression in Mononuclear Phagocytes
Infect. Immun.,
July 1, 2006;
74(7):
3912 - 3921.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
R. Niwa, M. Sakurada, Y. Kobayashi, A. Uehara, K. Matsushima, R. Ueda, K. Nakamura, and K. Shitara
Enhanced Natural Killer Cell Binding and Activation by Low-Fucose IgG1 Antibody Results in Potent Antibody-Dependent Cellular Cytotoxicity Induction at Lower Antigen Density
Clin. Cancer Res.,
March 15, 2005;
11(6):
2327 - 2336.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
B. OSTERUD and E. BJORKLID
Role of Monocytes in Atherogenesis
Physiol Rev,
October 1, 2003;
83(4):
1069 - 1112.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
S. Senechal, P. de Nadai, N. Ralainirina, A. Scherpereel, H. Vorng, P. Lassalle, A.-B. Tonnel, A. Tsicopoulos, and B. Wallaert
Effect of Diesel on Chemokines and Chemokine Receptors Involved in Helper T Cell Type 1/Type 2 Recruitment in Patients with Asthma
Am. J. Respir. Crit. Care Med.,
July 15, 2003;
168(2):
215 - 221.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
K. Ichiyama, S. Yokoyama-Kumakura, Y. Tanaka, R. Tanaka, K. Hirose, K. Bannai, T. Edamatsu, M. Yanaka, Y. Niitani, N. Miyano-Kurosaki, et al.
A duodenally absorbable CXC chemokine receptor 4 antagonist, KRH-1636, exhibits a potent and selective anti-HIV-1 activity
PNAS,
April 1, 2003;
100(7):
4185 - 4190.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
L. Agrawal, Z. Vanhorn-Ali, and G. Alkhatib
Multiple determinants are involved in HIV coreceptor use as demonstrated by CCR4/CCL22 interaction in peripheral blood mononuclear cells (PBMCs)
J. Leukoc. Biol.,
November 1, 2002;
72(5):
1063 - 1074.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
C.-C. Ku, J. A. Padilla, C. Grose, E. C. Butcher, and A. M. Arvin
Tropism of Varicella-Zoster Virus for Human Tonsillar CD4+ T Lymphocytes That Express Activation, Memory, and Skin Homing Markers
J. Virol.,
October 11, 2002;
76(22):
11425 - 11433.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
H. Katayama, A. Yokoyama, N. Kohno, K. Sakai, K. Hiwada, H. Yamada, and K. Hirai
Production of Eosinophilic Chemokines by Normal Pleural Mesothelial Cells
Am. J. Respir. Cell Mol. Biol.,
April 1, 2002;
26(4):
398 - 403.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
A. Prat, K. Biernacki, J.-F. Lavoie, J. Poirier, P. Duquette, and J. P. Antel
Migration of Multiple Sclerosis Lymphocytes Through Brain Endothelium
Arch Neurol,
March 1, 2002;
59(3):
391 - 397.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
L. A. Jopling, I. Sabroe, D. P. Andrew, T. J. Mitchell, Y. Li, M. R. Hodge, T. J. Williams, and J. E. Pease
The Identification, Characterization, and Distribution of Guinea Pig CCR4 and Epitope Mapping of a Blocking Antibody
J. Biol. Chem.,
February 22, 2002;
277(9):
6864 - 6873.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
E. A. de Wynter, C. M. Heyworth, N. Mukaida, E. Jaworska, A. Weffort-Santos, K. Matushima, and N. G. Testa
CCR1 chemokine receptor expression isolates erythroid from granulocyte-macrophage progenitors
J. Leukoc. Biol.,
September 1, 2001;
70(3):
455 - 460.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
M. Iikura, M. Miyamasu, M. Yamaguchi, H. Kawasaki, K. Matsushima, M. Kitaura, Y. Morita, O. Yoshie, K. Yamamoto, and K. Hirai
Chemokine receptors in human basophils: inducible expression of functional CXCR4
J. Leukoc. Biol.,
July 1, 2001;
70(1):
113 - 120.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
C. Blanpain, R. Buser, C. A. Power, M. Edgerton, C. Buchanan, M. Mack, G. Simmons, P. R. Clapham, M. Parmentier, and A. E. I. Proudfoot
A chimeric MIP-1{alpha}/RANTES protein demonstrates the use of different regions of the RANTES protein to bind and activate its receptors
J. Leukoc. Biol.,
June 1, 2001;
69(6):
977 - 985.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
Y. Kim, S.-s. J. Sung, W. A. Kuziel, S. Feldman, S. M. Fu, and C. E. Rose Jr
Enhanced Airway Th2 Response After Allergen Challenge in Mice Deficient in CC Chemokine Receptor-2 (CCR2)
J. Immunol.,
April 15, 2001;
166(8):
5183 - 5192.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
A. Heinemann, A. Hartnell, V. E. L. Stubbs, K. Murakami, D. Soler, G. LaRosa, P. W. Askenase, T. J. Williams, and I. Sabroe
Basophil Responses to Chemokines Are Regulated by Both Sequential and Cooperative Receptor Signaling
J. Immunol.,
December 15, 2000;
165(12):
7224 - 7233.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
K. J. Clemetson, J. M. Clemetson, A. E. I. Proudfoot, C. A. Power, M. Baggiolini, and T. N. C. Wells
Functional expression of CCR1, CCR3, CCR4, and CXCR4 chemokine receptors on human platelets
Blood,
December 15, 2000;
96(13):
4046 - 4054.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
T. Nanki and P. E. Lipsky
Lack of correlation between chemokine receptor and Th1/Th2 cytokine expression by individual memory T cells
Int. Immunol.,
December 1, 2000;
12(12):
1659 - 1667.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
T. Nanki, K. Hayashida, H. S. El-Gabalawy, S. Suson, K. Shi, H. J. Girschick, S. Yavuz, and P. E. Lipsky
Stromal Cell-Derived Factor-1-CXC Chemokine Receptor 4 Interactions Play a Central Role in CD4+ T Cell Accumulation in Rheumatoid Arthritis Synovium
J. Immunol.,
December 1, 2000;
165(11):
6590 - 6598.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
J. A. Belperio, M. D. Burdick, M. P. Keane, Y. Y. Xue, J. P. Lynch III, B. L. Daugherty, S. L. Kunkel, and R. M. Strieter
The Role of the CC Chemokine, RANTES, in Acute Lung Allograft Rejection
J. Immunol.,
July 1, 2000;
165(1):
461 - 472.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
Y. Chvatchko, A. J. Hoogewerf, A. Meyer, S. Alouani, P. Juillard, R. Buser, F. Conquet, A. E.I. Proudfoot, T. N.C. Wells, and C. A. Power
A Key Role for CC Chemokine Receptor 4 in Lipopolysaccharide-induced Endotoxic Shock
J. Exp. Med.,
May 15, 2000;
191(10):
1755 - 1764.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
C. Murdoch and A. Finn
Chemokine receptors and their role in inflammation and infectious diseases
Blood,
May 15, 2000;
95(10):
3032 - 3043.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
K. Arima, K. Nasu, H. Narahara, K. Fujisawa, N. Matsui, and I. Miyakawa
Effects of lipopolysaccharide and cytokines on production of RANTES by cultured human endometrial stromal cells
Mol. Hum. Reprod.,
March 1, 2000;
6(3):
246 - 251.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
P. M. Murphy, M. Baggiolini, I. F. Charo, C. A. Hebert, R. Horuk, K. Matsushima, L. H. Miller, J. J. Oppenheim, and C. A. Power
International Union of Pharmacology. XXII. Nomenclature for Chemokine Receptors
Pharmacol. Rev.,
March 1, 2000;
52(1):
145 - 176.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
N. Nasreen, K. A. Mohammed, G. Galffy, M. J. Ward, and V. B. Antony
MCP-1 in pleural injury: CCR2 mediates haptotaxis of pleural mesothelial cells
Am J Physiol Lung Cell Mol Physiol,
March 1, 2000;
278(3):
L591 - L598.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
G. Franchin, G. Zybarth, W. W. Dai, L. Dubrovsky, N. Reiling, H. Schmidtmayerova, M. Bukrinsky, and B. Sherry
Lipopolysaccharide Inhibits HIV-1 Infection of Monocyte- Derived Macrophages Through Direct and Sustained Down-Regulation of CC Chemokine Receptor 5
J. Immunol.,
March 1, 2000;
164(5):
2592 - 2601.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
C.-R. Yu, K. W. C. Peden, M. B. Zaitseva, H. Golding, and J. M. Farber
CCR9A and CCR9B: Two Receptors for the Chemokine CCL25/TECK/Ck{beta}-15 That Differ in Their Sensitivities to Ligand
J. Immunol.,
February 1, 2000;
164(3):
1293 - 1305.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
A. M. Norment, L. Y. Bogatzki, B. N. Gantner, and M. J. Bevan
Murine CCR9, a Chemokine Receptor for Thymus-Expressed Chemokine That Is Up-Regulated Following Pre-TCR Signaling
J. Immunol.,
January 15, 2000;
164(2):
639 - 648.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
J. M. Burns, G. K. Lewis, and A. L. DeVico
Soluble complexes of regulated upon activation, normal T cells expressed and secreted (RANTES) and glycosaminoglycans suppress HIV-1 infection but do not induce Ca2+ signaling
PNAS,
December 7, 1999;
96(25):
14499 - 14504.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
S. Ying, Q. Meng, K. Zeibecoglou, D. S. Robinson, A. Macfarlane, M. Humbert, and A. B. Kay
Eosinophil Chemotactic Chemokines (Eotaxin, Eotaxin-2, RANTES, Monocyte Chemoattractant Protein-3 (MCP-3), and MCP-4), and C-C Chemokine Receptor 3 Expression in Bronchial Biopsies from Atopic and Nonatopic (Intrinsic) Asthmatics
J. Immunol.,
December 1, 1999;
163(11):
6321 - 6329.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
A. J. Morris and C. C. Malbon
Physiological Regulation of G Protein-Linked Signaling
Physiol Rev,
October 1, 1999;
79(4):
1373 - 1430.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
K F Chung and P J Barnes
Cytokines in asthma
Thorax,
September 1, 1999;
54(9):
825 - 857.
[Full Text]
|
 |
|

|
 |

|
 |
 
F. Hadida, V. Vieillard, L. Mollet, I. Clark-Lewis, M. Baggiolini, and P. Debre
Cutting Edge: RANTES Regulates Fas Ligand Expression and Killing by HIV-Specific CD8 Cytotoxic T Cells
J. Immunol.,
August 1, 1999;
163(3):
1105 - 1109.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
M. Foti, F. Granucci, D. Aggujaro, E. Liboi, W. Luini, S. Minardi, A. Mantovani, S. Sozzani, and P. Ricciardi-Castagnoli
Upon dendritic cell (DC) activation chemokines and chemokine receptor expression are rapidly regulated for recruitment and maintenance of DC at the inflammatory site
Int. Immunol.,
June 1, 1999;
11(6):
979 - 986.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
M. A. Giembycz and M. A. Lindsay
Pharmacology of the Eosinophil
Pharmacol. Rev.,
June 1, 1999;
51(2):
213 - 340.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
J. Dürig, N. G. Testa, and C. M. Heyworth
Distinct Biological Effects of Macrophage Inflammatory Protein-1{alpha} and Stroma-Derived Factor-1{alpha} on CD34+ Hemopoietic Cells
Stem Cells,
March 1, 1999;
17(2):
62 - 71.
[Abstract]
[Full Text]
|
 |
|

|
 |

|
 |
 
L. Pedroza-Martins, K. B. Gurney, B. E. Torbett, and C. H. Uittenbogaart
Differential Tropism and Replication Kinetics of Human Immunodeficiency Virus Type 1 Isolates in Thymocytes: Coreceptor Expression Allows Viral Entry, but Productive Infection of Distinct Subsets Is Determined at the Postentry Level
J. Virol.,
December 1, 1998;
72(12):
9441 - 9452.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
P. J. Barnes, K. F. Chung, and C. P. Page
Inflammatory Mediators of Asthma: An Update
Pharmacol. Rev.,
December 1, 1998;
50(4):
515 - 596.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
D. D'Ambrosio, A. Iellem, R. Bonecchi, D. Mazzeo, S. Sozzani, A. Mantovani, and F. Sinigaglia
Cutting Edge: Selective Up-Regulation of Chemokine Receptors CCR4 and CCR8 upon Activation of Polarized Human Type 2 Th Cells
J. Immunol.,
November 15, 1998;
161(10):
5111 - 5115.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
J. Durig, E. A. de Wynter, C. Kasper, M. A. Cross, J. Chang, N. G. Testa, and C. M. Heyworth
Expression of Macrophage Inflammatory Protein-1alpha Receptors in Human CD34+ Hematopoietic Cells and Their Modulation by Tumor Necrosis Factor-alpha and Interferon-gamma
Blood,
November 1, 1998;
92(9):
3073 - 3081.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
A. Albini, S. Ferrini, R. Benelli, S. Sforzini, D. Giunciuglio, M. G. Aluigi, A. E. I. Proudfoot, S. Alouani, T. N. C. Wells, G. Mariani, et al.
HIV-1 Tat protein mimicry of chemokines
PNAS,
October 27, 1998;
95(22):
13153 - 13158.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
S. Struyf, P. Proost, S. Sozzani, A. Mantovani, A. Wuyts, E. De Clercq, D. Schols, and J. Van Damme
Cutting Edge: Enhanced Anti-HIV-1 Activity and Altered Chemotactic Potency of NH2-Terminally Processed Macrophage-Derived Chemokine (MDC) Imply an Additional MDC Receptor
J. Immunol.,
September 15, 1998;
161(6):
2672 - 2675.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
E.A. de Wynter, J. Durig, M.A. Cross, C.M. Heyworth, and N.G. Testa
Differential Response of CD34+ Cells Isolated from Cord Blood and Bone Marrow to MIP-1{alpha} and the Expression of MIP-1{alpha} Receptors on These Immature Cells
Stem Cells,
September 1, 1998;
16(5):
349 - 356.
[Abstract]
[Full Text]
|
 |
|

|
 |

|
 |
 
F. Hadida, V. Vieillard, B. Autran, I. Clark-Lewis, M. Baggiolini, and P. Debre
HIV-specific T Cell Cytotoxicity Mediated by RANTES Via the Chemokine Receptor CCR3
J. Exp. Med.,
August 3, 1998;
188(3):
609 - 614.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
O. Pleskoff, C. Treboute, and M. Alizon
The Cytomegalovirus-Encoded Chemokine Receptor US28 Can Enhance Cell-Cell Fusion Mediated by Different Viral Proteins
J. Virol.,
August 1, 1998;
72(8):
6389 - 6397.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
M. Mellado, J. M. Rodriguez-Frade, A. Aragay, G. del Real, A. M. Martin, A. J. Vila-Coro, A. Serrano, F. Mayor Jr., and C. Martinez-A.
The Chemokine Monocyte Chemotactic Protein 1 Triggers Janus Kinase 2 Activation and Tyrosine Phosphorylation of the CCR2B Receptor
J. Immunol.,
July 15, 1998;
161(2):
805 - 813.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
F. Sallusto, D. Lenig, C. R. Mackay, and A. Lanzavecchia
Flexible Programs of Chemokine Receptor Expression on Human Polarized T Helper 1 and 2 Lymphocytes
J. Exp. Med.,
March 16, 1998;
187(6):
875 - 883.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
I. M. Hayes, N. J. Jordan, S. Towers, G. Smith, J. R. Paterson, J. J. Earnshaw, A. G. Roach, J. Westwick, and R. J. Williams
Human Vascular Smooth Muscle Cells Express Receptors for CC Chemokines
Arterioscler. Thromb. Vasc. Biol.,
March 1, 1998;
18(3):
397 - 403.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
B. Lu, B. J. Rutledge, L. Gu, J. Fiorillo, N. W. Lukacs, S. L. Kunkel, R. North, C. Gerard, and B. J. Rollins
Abnormalities in Monocyte Recruitment and Cytokine Expression in Monocyte Chemoattractant Protein 1-deficient Mice
J. Exp. Med.,
February 16, 1998;
187(4):
601 - 608.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
S. K. Gupta, P. G. Lysko, K. Pillarisetti, E. Ohlstein, and J. M. Stadel
Chemokine Receptors in Human Endothelial Cells. FUNCTIONAL EXPRESSION OF CXCR4 AND ITS TRANSCRIPTIONAL REGULATION BY INFLAMMATORY CYTOKINES
J. Biol. Chem.,
February 13, 1998;
273(7):
4282 - 4287.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
H. L. Tiffany, G. Alkhatib, C. Combadiere, E. A. Berger, and P. M. Murphy
CC Chemokine Receptors 1 and 3 Are Differentially Regulated by IL-5 During Maturation of Eosinophilic HL-60 Cells
J. Immunol.,
February 1, 1998;
160(3):
1385 - 1392.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
T. Imai, D. Chantry, C. J. Raport, C. L. Wood, M. Nishimura, R. Godiska, O. Yoshie, and P. W. Gray
Macrophage-derived Chemokine Is a Functional Ligand for the CC Chemokine Receptor 4
J. Biol. Chem.,
January 16, 1998;
273(3):
1764 - 1768.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
R. J. B. Nibbs, S. M. Wylie, J. Yang, N. R. Landau, and G. J. Graham
Cloning and Characterization of a Novel Promiscuous Human beta -Chemokine Receptor D6
J. Biol. Chem.,
December 19, 1997;
272(51):
32078 - 32083.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
H. M. Sarau, J. A. Rush, J. J. Foley, M. E. Brawner, D. B. Schmidt, J. R. White, and M. S. Barnette
Characterization of Functional Chemokine Receptors (CCR1 and CCR2) on EoL-3 Cells: A Model System to Examine the Role of Chemokines in Cell Function
J. Pharmacol. Exp. Ther.,
October 1, 1997;
283(1):
411 - 418.
[Abstract]
[Full Text]
|
 |
|

|
 |

|
 |
 
C. A. Power, D. J. Church, A. Meyer, S. Alouani, A. E.I. Proudfoot, I. Clark-Lewis, S. Sozzani, A. Mantovani, and T. N.C. Wells
Cloning and Characterization of a Specific Receptor for the Novel CC Chemokine MIP-3alpha from Lung Dendritic Cells
J. Exp. Med.,
September 15, 1997;
186(6):
825 - 835.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
B. J. Rollins
Chemokines
Blood,
August 1, 1997;
90(3):
909 - 928.
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
H. L. Tiffany, L. L. Lautens, J.-L. Gao, J. Pease, M. Locati, C. Combadiere, W. Modi, T. I. Bonner, and P. M. Murphy
Identification of CCR8: A Human Monocyte and Thymus Receptor for the CC Chemokine I-309
J. Exp. Med.,
July 7, 1997;
186(1):
165 - 170.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
T. A. Berkhout, H. M. Sarau, K. Moores, J. R White, N. Elshourbagy, E. Appelbaum, J. Makwana, J. J. Foley, D. B Schmidt, C. Imburgia, et al.
Cloning, in Vitro Expression, and Functional Characterization of a Novel Human CC Chemokine of the Monocyte Chemotactic Protein (MCP) Family (MCP-4) That Binds and Signals through the CC Chemokine Receptor 2B
J. Biol. Chem.,
June 27, 1997;
272(26):
16404 - 16413.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
B.-S. Youn, S.-H. Kim, M. S. Lyu, C. A. Kozak, D. D. Taub, and B. S. Kwon
Molecular Cloning and Characterization of a cDNA, CHEMR1, Encoding a Chemokine Receptor With a Homology to the Human C-C Chemokine Receptor, CCR-4
Blood,
June 15, 1997;
89(12):
4448 - 4460.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
M. Baba, T. Imai, M. Nishimura, M. Kakizaki, S. Takagi, K. Hieshima, H. Nomiyama, and O. Yoshie
Identification of CCR6, the Specific Receptor for a Novel Lymphocyte-directed CC Chemokine LARC
J. Biol. Chem.,
June 6, 1997;
272(23):
14893 - 14898.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
T. Imai, M. Baba, M. Nishimura, M. Kakizaki, S. Takagi, and O. Yoshie
The T Cell-directed CC Chemokine TARC Is a Highly Specific Biological Ligand for CC Chemokine Receptor 4
J. Biol. Chem.,
June 6, 1997;
272(23):
15036 - 15042.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
J.-L. Gao, T. A. Wynn, Y. Chang, E. J. Lee, H. E. Broxmeyer, S. Cooper, H. L. Tiffany, H. Westphal, J. Kwon-Chung, and P. M. Murphy
Impaired Host Defense, Hematopoiesis, Granulomatous Inflammation and Type 1-Type 2 Cytokine Balance in Mice Lacking CC Chemokine Receptor 1
J. Exp. Med.,
June 2, 1997;
185(11):
1959 - 1968.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
R. Yoshida, T. Imai, K. Hieshima, J. Kusuda, M. Baba, M. Kitaura, M. Nishimura, M. Kakizaki, H. Nomiyama, and O. Yoshie
Molecular Cloning of a Novel Human CC Chemokine EBI1-ligand Chemokine That Is a Specific Functional Ligand for EBI1, CCR7
J. Biol. Chem.,
May 23, 1997;
272(21):
13803 - 13809.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
R. Godiska, D. Chantry, C. J. Raport, S. Sozzani, P. Allavena, D. Leviten, A. Mantovani, and P. W. Gray
Human Macrophage-derived Chemokine (MDC), a Novel Chemoattractant for Monocytes, Monocyte-derived Dendritic Cells, and Natural Killer Cells
J. Exp. Med.,
May 5, 1997;
185(9):
1595 - 1604.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
L.-M. Wong, S. J. Myers, C.-L. Tsou, J. Gosling, H. Arai, and I. F. Charo
Organization and Differential Expression of the Human Monocyte Chemoattractant Protein 1Receptor Gene. EVIDENCE FOR THE ROLE OF THE CARBOXYL-TERMINAL TAIL IN RECEPTOR TRAFFICKING
J. Biol. Chem.,
January 10, 1997;
272(2):
1038 - 1045.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
C.-A. N. Dunstan, M. N. Salafranca, S. Adhikari, Y. Xia, L. Feng, and J. K. Harrison
Identification of Two Rat Genes Orthologous to the Human Interleukin-8 Receptors
J. Biol. Chem.,
December 20, 1996;
271(51):
32770 - 32776.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
T. Imai, T. Yoshida, M. Baba, M. Nishimura, M. Kakizaki, and O. Yoshie
Molecular Cloning of a Novel T Cell-directed CC Chemokine Expressed in Thymus by Signal Sequence Trap Using Epstein-Barr Virus Vector
J. Biol. Chem.,
August 30, 1996;
271(35):
21514 - 21521.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
S. K. Ahuja and P. M. Murphy
The CXC Chemokines Growth-regulated Oncogene (GRO) alpha , GRObeta , GROgamma , Neutrophil-activating Peptide-2, and Epithelial Cell-derived Neutrophil-activating Peptide-78 Are Potent Agonists for the Type B, but Not the Type A, Human Interleukin-8 Receptor
J. Biol. Chem.,
August 23, 1996;
271(34):
20545 - 20550.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
F. S. Monteclaro and I. F. Charo
The Amino-terminal Extracellular Domain of the MCP-1 Receptor, but Not the RANTES/MIP-1alpha Receptor, Confers Chemokine Selectivity. EVIDENCE FOR A TWO-STEP MECHANISM FOR MCP-1 RECEPTOR ACTIVATION
J. Biol. Chem.,
August 9, 1996;
271(32):
19084 - 19092.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
C. J. Raport, J. Gosling, V. L. Schweickart, P. W. Gray, and I. F. Charo
Molecular Cloning and Functional Characterization of a Novel Human CC Chemokine Receptor (CCR5) for RANTES, MIP-1beta , and MIP-1alpha
J. Biol. Chem.,
July 19, 1996;
271(29):
17161 - 17166.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
A. Meyer, A. J. Coyle, A. E.I. Proudfoot, T. N.C. Wells, and C. A. Power
Cloning and Characterization of a Novel Murine Macrophage Inflammatory Protein-1alpha Receptor
J. Biol. Chem.,
June 14, 1996;
271(24):
14445 - 14451.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
J.-H. Gong, M. Uguccioni, B. Dewald, M. Baggiolini, and I. Clark-Lewis
RANTES and MCP-3 Antagonists Bind Multiple Chemokine Receptors
J. Biol. Chem.,
May 3, 1996;
271(18):
10521 - 10527.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
M. Kitaura, T. Nakajima, T. Imai, S. Harada, C. Combadiere, H. L. Tiffany, P. M. Murphy, and O. Yoshie
Molecular Cloning of Human Eotaxin, an Eosinophil-selective CC Chemokine, and Identification of a Specific Eosinophil Eotaxin Receptor, CC Chemokine Receptor 3
J. Biol. Chem.,
March 29, 1996;
271(13):
7725 - 7730.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
M. Lusti-Narasimhan, A. Chollet, C. A. Power, B. Allet, A. E. I. Proudfoot, and T. N. C. Wells
A Molecular Switch of Chemokine Receptor Selectivity
J. Biol. Chem.,
February 9, 1996;
271(6):
3148 - 3153.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
C. Combadiere, S. K. Ahuja, J. Van Damme, H. L. Tiffany, J.-L. Gao, and P. M. Murphy
Monocyte Chemoattractant Protein-3 Is a Functional Ligand for CC Chemokine Receptors 1 and 2B
J. Biol. Chem.,
December 15, 1995;
270(50):
29671 - 29675.
[Abstract]
[Full Text]
[PDF]
|
 |
|
Copyright © 1995 by the American Society for Biochemistry and Molecular Biology.
|
Advertisement
Advertisement
|