JBC

HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Wilkins, P. P.
Right arrow Articles by Cummings, R. D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Wilkins, P. P.
Right arrow Articles by Cummings, R. D.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?

Volume 270, Number 39, Issue of September 29, pp. 22677-22680, 1995
©1995 by The American Society for Biochemistry and Molecular Biology, Inc.
Tyrosine Sulfation of P-selectin Glycoprotein Ligand-1 Is Required for High Affinity Binding to P-selectin

(Received for publication, July 5, 1995; and in revised form, August 4, 1995)

Patricia P. Wilkins ,  Kevin L. Moore , ,  Rodger P. McEver , , , ,  Richard D. Cummings

P-selectin glycoprotein ligand-1 (PSGL-1) is a mucin-like glycoprotein on leukocytes that is a high affinity ligand for P-selectin. Previous studies have shown that sialylation and fucosylation of PSGL-1 are required for its binding to P-selectin, but other post-translational modifications of PSGL-1 may also be important. We demonstrate that PSGL-1 synthesized in human HL-60 cells can be metabolically labeled with [S]sulfate that is incorporated primarily into tyrosine sulfate. Treatment of PSGL-1 with a bacterial arylsulfatase releases sulfate from tyrosine, resulting in a concordant decrease in binding to P-selectin. These studies demonstrate that tyrosine sulfate on PSGL-1 functions in conjunction with sialylated and fucosylated glycans to mediate high affinity binding to P-selectin.



Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?


This article has been cited by other articles:


Home page
 J. Immunol.Home page
S. C. Kerr, C. B. Fieger, K. R. Snapp, and S. D. Rosen
Endoglycan, a Member of the CD34 Family of Sialomucins, Is a Ligand for the Vascular Selectins
J. Immunol., July 15, 2008; 181(2): 1480 - 1490.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
A. J. Hoffhines, E. Damoc, K. G. Bridges, J. A. Leary, and K. L. Moore
Detection and Purification of Tyrosine-sulfated Proteins Using a Novel Anti-sulfotyrosine Monoclonal Antibody
J. Biol. Chem., December 8, 2006; 281(49): 37877 - 37887.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Endocrinol.Home page
M. Bonomi, M. Busnelli, L. Persani, G. Vassart, and S. Costagliola
Structural Differences in the Hinge Region of the Glycoprotein Hormone Receptors: Evidence from the Sulfated Tyrosine Residues
Mol. Endocrinol., December 1, 2006; 20(12): 3351 - 3363.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. ProteomicsHome page
J. W. Kehoe, N. Velappan, M. Walbolt, J. Rasmussen, D. King, J. Lou, K. Knopp, P. Pavlik, J. D. Marks, C. R. Bertozzi, et al.
Using Phage Display to Select Antibodies Recognizing Post-translational Modifications Independently of Sequence Context
Mol. Cell. Proteomics, December 1, 2006; 5(12): 2350 - 2363.
[Abstract] [Full Text] [PDF]

Home page
 J BiochemHome page
E. Mishiro, Y. Sakakibara, M.-C. Liu, and M. Suiko
Differential Enzymatic Characteristics and Tissue-Specific Expression of Human TPST-1 and TPST-2
J. Biochem., November 1, 2006; 140(5): 731 - 737.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
Z. Ni, J. J. Campbell, G. Niehans, and B. Walcheck
The Monoclonal Antibody CHO-131 Identifies a Subset of Cutaneous Lymphocyte-Associated Antigen T Cells Enriched in P-Selectin-Binding Cells
J. Immunol., October 1, 2006; 177(7): 4742 - 4748.
[Abstract] [Full Text] [PDF]

Home page
 BloodHome page
G. M. Lord, R. M. Rao, H. Choe, B. M. Sullivan, A. H. Lichtman, F. W. Luscinskas, and L. H. Glimcher
T-bet is required for optimal proinflammatory CD4+ T-cell trafficking
Blood, November 15, 2005; 106(10): 3432 - 3439.
[Abstract] [Full Text] [PDF]

Home page
 BloodHome page
E. Mikaelsson, A. H. Danesh-Manesh, A. Luppert, M. Jeddi-Tehrani, M.-R. Rezvany, R. A. Sharifian, R. Safaie, A. Roohi, A. Osterborg, F. Shokri, et al.
Fibromodulin, an extracellular matrix protein: characterization of its unique gene and protein expression in B-cell chronic lymphocytic leukemia and mantle cell lymphoma
Blood, June 15, 2005; 105(12): 4828 - 4835.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
J. S. Merzaban, J. Zuccolo, S. Y. Corbel, M. J. Williams, and H. J. Ziltener
An Alternate Core 2 {beta}1,6-N-Acetylglucosaminyltransferase Selectively Contributes to P-Selectin Ligand Formation in Activated CD8 T Cells
J. Immunol., April 1, 2005; 174(7): 4051 - 4059.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
T. Hirata, Y. Furukawa, B.-G. Yang, K. Hieshima, M. Fukuda, R. Kannagi, O. Yoshie, and M. Miyasaka
Human P-selectin Glycoprotein Ligand-1 (PSGL-1) Interacts with the Skin-associated Chemokine CCL27 via Sulfated Tyrosines at the PSGL-1 Amino Terminus
J. Biol. Chem., December 10, 2004; 279(50): 51775 - 51782.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
M. J. Smith, B. R. E. Smith, M. B. Lawrence, and K. R. Snapp
Functional Analysis of the Combined Role of the O-Linked Branching Enzyme Core 2 {beta}1-6-N-Glucosaminyltransferase and Dimerization of P-selectin Glycoprotein Ligand-1 in Rolling on P-selectin
J. Biol. Chem., May 21, 2004; 279(21): 21984 - 21991.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Pathol.Home page
S. Mathieu, M. Prorok, A.-M. Benoliel, R. Uch, C. Langlet, P. Bongrand, R. Gerolami, and A. El-Battari
Transgene Expression of {alpha}(1,2)-Fucosyltransferase-I (FUT1) in Tumor Cells Selectively Inhibits Sialyl-Lewis x Expression and Binding to E-Selectin without Affecting Synthesis of Sialyl-Lewis a or Binding to P-Selectin
Am. J. Pathol., February 1, 2004; 164(2): 371 - 383.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
P. Onnerfjord, T. F. Heathfield, and D. Heinegard
Identification of Tyrosine Sulfation in Extracellular Leucine-rich Repeat Proteins Using Mass Spectrometry
J. Biol. Chem., January 2, 2004; 279(1): 26 - 33.
[Abstract] [Full Text] [PDF]

Home page
 J. Exp. Med.Home page
K. Ley
Sulfated Sugars for Rolling Lymphocytes
J. Exp. Med., November 3, 2003; 198(9): 1285 - 1288.
[Full Text] [PDF]

Home page
 BloodHome page
J. A. Carlyon, M. Akkoyunlu, L. Xia, T. Yago, T. Wang, R. D. Cummings, R. P. McEver, and E. Fikrig
Murine neutrophils require {alpha}1,3-fucosylation but not PSGL-1 for productive infection with Anaplasma phagocytophilum
Blood, November 1, 2003; 102(9): 3387 - 3395.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
T. Yago, A. Leppanen, J. A. Carlyon, M. Akkoyunlu, S. Karmakar, E. Fikrig, R. D. Cummings, and R. P. McEver
Structurally Distinct Requirements for Binding of P-selectin Glycoprotein Ligand-1 and Sialyl Lewis x to Anaplasma phagocytophilum and P-selectin
J. Biol. Chem., September 26, 2003; 278(39): 37987 - 37997.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
A. Leppanen, T. Yago, V. I. Otto, R. P. McEver, and R. D. Cummings
Model Glycosulfopeptides from P-selectin Glycoprotein Ligand-1 Require Tyrosine Sulfation and a Core 2-branched O-Glycan to Bind to L-selectin
J. Biol. Chem., July 11, 2003; 278(29): 26391 - 26400.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
K. L. Moore
The Biology and Enzymology of Protein Tyrosine O-Sulfation
J. Biol. Chem., June 27, 2003; 278(27): 24243 - 24246.
[Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
C. C. M. Appeldoorn, T. J. M. Molenaar, A. Bonnefoy, S. H. van Leeuwen, P. A. H. Vandervoort, M. F. Hoylaerts, T. J. C. van Berkel, and E. A. L. Biessen
Rational Optimization of a Short Human P-selectin-binding Peptide Leads to Nanomolar Affinity Antagonists
J. Biol. Chem., March 14, 2003; 278(12): 10201 - 10207.
[Abstract] [Full Text] [PDF]

Home page
 BloodHome page
L. Xia, V. Ramachandran, J. M. McDaniel, K. N. Nguyen, R. D. Cummings, and R. P. McEver
N-terminal residues in murine P-selectin glycoprotein ligand-1 required for binding to murine P-selectin
Blood, January 15, 2003; 101(2): 552 - 559.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
M. P. Bernimoulin, X.-L. Zeng, C. Abbal, S. Giraud, M. Martinez, O. Michielin, M. Schapira, and O. Spertini
Molecular Basis of Leukocyte Rolling on PSGL-1. PREDOMINANT ROLE OF CORE-2 O-GLYCANS AND OF TYROSINE SULFATE RESIDUE 51
J. Biol. Chem., January 3, 2003; 278(1): 37 - 47.
[Abstract] [Full Text] [PDF]

Home page
 BloodHome page
M. M. A. Kobzdej, A. Leppanen, V. Ramachandran, R. D. Cummings, and R. P. McEver
Discordant expression of selectin ligands and sialyl Lewis x-related epitopes on murine myeloid cells
Blood, December 15, 2002; 100(13): 4485 - 4494.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
M.-C. Huang, A. Laskowska, D. Vestweber, and M. K. Wild
The alpha (1,3)-Fucosyltransferase Fuc-TIV, but Not Fuc-TVII, Generates Sialyl Lewis X-like Epitopes Preferentially on Glycolipids
J. Biol. Chem., November 27, 2002; 277(49): 47786 - 47795.
[Abstract] [Full Text] [PDF]

Home page
 Endocr. Rev.Home page
C. A. Strott
Sulfonation and Molecular Action
Endocr. Rev., October 1, 2002; 23(5): 703 - 732.
[Abstract] [Full Text] [PDF]

Home page
 GlycobiologyHome page
M. Delcommenne, R. Kannagi, and P. Johnson
TNF-{alpha} increases the carbohydrate sulfation of CD44: induction of 6-sulfo N-acetyl lactosamine on N- and O-linked glycans
Glycobiology, October 1, 2002; 12(10): 613 - 622.
[Abstract] [Full Text] [PDF]

Home page
 J. Leukoc. Biol.Home page
A. Thatte, S. Ficarro, K. R. Snapp, M. K. Wild, D. Vestweber, D. F. Hunt, and K. F. Ley
Binding of function-blocking mAbs to mouse and human P-selectin glycoprotein ligand-1 peptides with and without tyrosine sulfation
J. Leukoc. Biol., September 1, 2002; 72(3): 470 - 477.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
A. Kanamori, N. Kojima, K. Uchimura, T. Muramatsu, T. Tamatani, M. C. Berndt, G. S. Kansas, and R. Kannagi
Distinct Sulfation Requirements of Selectins Disclosed Using Cells That Support Rolling Mediated by All Three Selectins under Shear Flow. L-SELECTIN PREFERS CARBOHYDRATE 6-SULFATION TO TYROSINE SULFATION, WHEREAS P-SELECTIN DOES NOT
J. Biol. Chem., August 30, 2002; 277(36): 32578 - 32586.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
Y.-B. Ouyang, J. T. B. Crawley, C. E. Aston, and K. L. Moore
Reduced Body Weight and Increased Postimplantation Fetal Death in Tyrosylprotein Sulfotransferase-1-deficient Mice
J. Biol. Chem., June 21, 2002; 277(26): 23781 - 23787.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
A. M. Fong, S. M. Alam, T. Imai, B. Haribabu, and D. D. Patel
CX3CR1 Tyrosine Sulfation Enhances Fractalkine-induced Cell Adhesion
J. Biol. Chem., May 24, 2002; 277(22): 19418 - 19423.
[Abstract] [Full Text] [PDF]

Home page
 BloodHome page
B. Walcheck, A. Leppanen, R. D. Cummings, R. N. Knibbs, L. M. Stoolman, S. R. Alexander, P. E. Mattila, and R. P. McEver
The monoclonal antibody CHO-131 binds to a core 2 O-glycan terminated with sialyl-Lewis x, which is a functional glycan ligand for P-selectin
Blood, May 13, 2002; 99(11): 4063 - 4069.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
Y.-Q. Ma and J.-G. Geng
Obligatory Requirement of Sulfation for P-Selectin Binding to Human Salivary Gland Carcinoma Acc-M Cells and Breast Carcinoma ZR-75-30 Cells
J. Immunol., February 15, 2002; 168(4): 1690 - 1696.
[Abstract] [Full Text] [PDF]

Home page
 J. Exp. Med.Home page
N. Bannert, S. Craig, M. Farzan, D. Sogah, N. V. Santo, H. Choe, and J. Sodroski
Sialylated O-Glycans and Sulfated Tyrosines in the NH2-Terminal Domain of CC Chemokine Receptor 5 Contribute to High Affinity Binding of Chemokines
J. Exp. Med., December 3, 2001; 194(11): 1661 - 1674.
[Abstract] [Full Text] [PDF]

Home page
 BloodHome page
E. E. Gardiner, M. De Luca, T. McNally, A. D. Michelson, R. K. Andrews, and M. C. Berndt
Regulation of P-selectin binding to the neutrophil P-selectin counter-receptor P-selectin glycoprotein ligand-1 by neutrophil elastase and cathepsin G
Blood, September 1, 2001; 98(5): 1440 - 1447.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
A. A. Preobrazhensky, S. Dragan, T. Kawano, M. A. Gavrilin, I. V. Gulina, L. Chakravarty, and P. E. Kolattukudy
Monocyte Chemotactic Protein-1 Receptor CCR2B Is a Glycoprotein That Has Tyrosine Sulfation in a Conserved Extracellular N-Terminal Region
J. Immunol., November 1, 2000; 165(9): 5295 - 5303.
[Abstract] [Full Text] [PDF]

Home page
 GlycobiologyHome page
S. Hemmerich and S. D. Rosen
MINI REVIEW Carbohydrate sulfotransferases in lymphocyte homing
Glycobiology, September 1, 2000; 10(9): 849 - 856.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
T. K. Epperson, K. D. Patel, R. P. McEver, and R. D. Cummings
Noncovalent Association of P-selectin Glycoprotein Ligand-1 and Minimal Determinants for Binding to P-selectin
J. Biol. Chem., March 10, 2000; 275(11): 7839 - 7853.
[Abstract] [Full Text] [PDF]

Home page
 FASEB J.Home page
S. BESSET, J.-B. VINCOURT, F. AMALRIC, and J.-P. GIRARD
Nuclear localization of PAPS synthetase 1: a sulfate activation pathway in the nucleus of eukaryotic cells
FASEB J, February 1, 2000; 14(2): 345 - 354.
[Abstract] [Full Text]

Home page
 J. Exp. Med.Home page
J. Yang, T. Hirata, K. Croce, G. Merrill-Skoloff, B. Tchernychev, E. Williams, R. Flaumenhaft, B. C. Furie, and B. Furie
Targeted Gene Disruption Demonstrates That P-Selectin Glycoprotein Ligand 1 (PSGL-1) Is Required for P-Selectin-mediated but Not E-Selectin-mediated Neutrophil Rolling and Migration
J. Exp. Med., December 20, 1999; 190(12): 1769 - 1782.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
V. Ramachandran, M. U. Nollert, H. Qiu, W.-J. Liu, R. D. Cummings, C. Zhu, and R. P. McEver
Tyrosine replacement in P-selectin glycoprotein ligand-1 affects distinct kinetic and mechanical properties of bonds with P- and L-selectin
PNAS, November 23, 1999; 96(24): 13771 - 13776.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
L. Tu, P. G. Murphy, X. Li, and T. F. Tedder
L-Selectin Ligands Expressed by Human Leukocytes Are HECA-452 Antibody-Defined Carbohydrate Epitopes Preferentially Displayed by P-Selectin Glycoprotein Ligand-1
J. Immunol., November 1, 1999; 163(9): 5070 - 5078.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Pathol.Home page
D. Figarella-Branger, L. Daniel, P. Andre, S. Guia, W. Renaud, G. Monti, E. Vivier, and G. Rougon
The PEN5 Epitope Identifies an Oligodendrocyte Precursor Cell Population and Pilocytic Astrocytomas
Am. J. Pathol., October 1, 1999; 155(4): 1261 - 1269.
[Abstract] [Full Text] [PDF]

Home page
 J. Exp. Med.Home page
G. M. Romo, J.-F. Dong, A. J. Schade, E. E. Gardiner, G. S. Kansas, C. Q. Li, L. V. McIntire, M. C. Berndt, and J. A. Lopez
The Glycoprotein Ib-IX-V Complex Is a Platelet Counterreceptor for P-Selectin
J. Exp. Med., September 20, 1999; 190(6): 803 - 814.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
A. Leppanen, P. Mehta, Y.-B. Ouyang, T. Ju, J. Helin, K. L. Moore, I. van Die, W. M. Canfield, R. P. McEver, and R. D. Cummings
A Novel Glycosulfopeptide Binds to P-selectin and Inhibits Leukocyte Adhesion to P-selectin
J. Biol. Chem., August 27, 1999; 274(35): 24838 - 24848.
[Abstract] [Full Text] [PDF]

Home page
 J. Cell Biol.Home page
A. Bistrup, S. Bhakta, J. K. Lee, Y. Y. Belov, M. D. Gunn, F.-R. Zuo, C.-C. Huang, R. Kannagi, S. D. Rosen, and S. Hemmerich
Sulfotransferases of Two Specificities Function in the Reconstitution of High Endothelial Cell Ligands for L-selectin
J. Cell Biol., May 17, 1999; 145(4): 899 - 910.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
P. Mehta, R. D. Cummings, and R. P. McEver
Affinity and Kinetic Analysis of P-selectin Binding to P-selectin Glycoprotein Ligand-1
J. Biol. Chem., December 4, 1998; 273(49): 32506 - 32513.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
Y.-B. Ouyang and K. L. Moore
Molecular Cloning and Expression of Human and Mouse Tyrosylprotein Sulfotransferase-2 and a Tyrosylprotein Sulfotransferase Homologue in Caenorhabditis elegans
J. Biol. Chem., September 18, 1998; 273(38): 24770 - 24774.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
R. Beisswanger, D. Corbeil, C. Vannier, C. Thiele, U. Dohrmann, R. Kellner, K. Ashman, C. Niehrs, and W. B. Huttner
Existence of distinct tyrosylprotein sulfotransferase genes: Molecular characterization of tyrosylprotein sulfotransferase-2
PNAS, September 15, 1998; 95(19): 11134 - 11139.
[Abstract] [Full Text] [PDF]

Home page
 J. Cell Biol.Home page
K. R. Snapp, R. Craig, M. Herron, R. D. Nelson, L. M. Stoolman, and G. S. Kansas
Dimerization of P-Selectin Glycoprotein Ligand-1 (PSGL-1) Required for Optimal Recognition of P-Selectin
J. Cell Biol., July 13, 1998; 142(1): 263 - 270.
[Abstract] [Full Text] [PDF]

Home page
 BloodHome page
D. B. Cines, E. S. Pollak, C. A. Buck, J. Loscalzo, G. A. Zimmerman, R. P. McEver, J. S. Pober, T. M. Wick, B. A. Konkle, B. S. Schwartz, et al.
Endothelial Cells in Physiology and in the Pathophysiology of Vascular Disorders
Blood, May 15, 1998; 91(10): 3527 - 3561.
[Full Text] [PDF]

Home page
 FASEB J.Home page
J.-P. Girard, E. S. Baekkevold, and F. Amalric
Sulfation in high endothelial venules: cloning and expression of the human PAPS synthetase
FASEB J, May 1, 1998; 12(7): 603 - 612.
[Abstract] [Full Text]

Home page
 J. Biol. Chem.Home page
W.-j. Liu, V. Ramachandran, J. Kang, T. K. Kishimoto, R. D. Cummings, and R. P. McEver
Identification of N-terminal Residues on P-selectin Glycoprotein Ligand-1 Required for Binding to P-selectin
J. Biol. Chem., March 20, 1998; 273(12): 7078 - 7087.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
Y.-b. Ouyang, W. S. Lane, and K. L. Moore
Tyrosylprotein sulfotransferase: Purification and molecular cloning of an enzyme that catalyzes tyrosine O-sulfation, a common posttranslational modification of eukaryotic proteins
PNAS, March 17, 1998; 95(6): 2896 - 2901.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
D. Torgersen, N. P. Mullin, and K. Drickamer
Mechanism of Ligand Binding to E- and P-selectin Analyzed Using Selectin/Mannose-binding Protein Chimeras
J. Biol. Chem., March 13, 1998; 273(11): 6254 - 6261.
[Abstract] [Full Text] [PDF]

Home page
 BloodHome page
C. L. Ramos, M. J. Smith, K. R. Snapp, G. S. Kansas, G. W. Stickney, K. Ley, and M. B. Lawrence
Functional Characterization of L-Selectin Ligands on Human Neutrophils and Leukemia Cell Lines: Evidence for Mucinlike Ligand Activity Distinct From P-Selectin Glycoprotein Ligand-1
Blood, February 1, 1998; 91(3): 1067 - 1075.
[Abstract] [Full Text] [PDF]

Home page
 BloodHome page
K. R. Snapp, H. Ding, K. Atkins, R. Warnke, F. W. Luscinskas, and G. S. Kansas
A Novel P-Selectin Glycoprotein Ligand-1 Monoclonal Antibody Recognizes an Epitope Within the Tyrosine Sulfate Motif of Human PSGL-1 and Blocks Recognition of Both P- and L-Selectin
Blood, January 1, 1998; 91(1): 154 - 164.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
K. I.-P. J. Hidari, A. S. Weyrich, G. A. Zimmerman, and R. P. McEver
Engagement of P-selectin Glycoprotein Ligand-1 Enhances Tyrosine Phosphorylation and Activates Mitogen-activated Protein Kinases in Human Neutrophils
J. Biol. Chem., November 7, 1997; 272(45): 28750 - 28756.
[Abstract] [Full Text] [PDF]