The type VIII capsular polysaccharide has been isolated and purified from a newly described strain of group B Streptococcus which is a leading cause of sepsis and neonatal meningitis in Japan. The polysaccharide contains D-glucose, D-galactose, L-rhamnose, and sialic acid in the molar ratio 1:1:1:1. By means of high resolution H nuclear magnetic resonance (H NMR), C NMR, and homo- and heterocorrelated NMR, the repeating unit structure of the type VIII polysaccharide was delineated as the following,

Enzymatic studies established this polysaccharide as the first from which sialic acid, linked to a branched -D-galactopyranosyl residue, is known to be removed by bacterial neuraminidase.

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