HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Olashaw, N. E. Search for Related Content PubMed PubMed Citation Articles by Olashaw, N. E. Social Bookmarking                      What's this?

Volume 271, Number 48, Issue of November 29, 1996 pp. 30307-30310
©1996 by The American Society for Biochemistry and Molecular Biology, Inc.

---

COMMUNICATION:
Inducible Activation of RelB in Fibroblasts

(Received for publication, March 12, 1996, and in revised form, August 28, 1996)

From the H. Lee Moffitt Cancer Center and Research Institute and Department of Anatomy, University of South Florida, Tampa, Florida 33612

RelB, a member of NF-B/Rel family of transcriptional regulators, is an immediate-early gene product that mediates constitutive lymphoid-specific B-directed gene expression. Data presented here show that RelB also functions as a mitogen-inducible DNA binding activity in fibroblasts. Activation of RelB was observed in three mouse fibroblast lines, and agents activating RelB in quiescent and cycling cells included platelet-derived growth factor, phorbol ester, and serum. Additional data implicate cyclic AMP in the regulation of RelB activity. These findings suggest that RelB may play different roles in different cell types.

CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

This article has been cited by other articles:

				B. Platzer, A. Jorgl, S. Taschner, B. Hocher, and H. Strobl RelB regulates human dendritic cell subset development by promoting monocyte intermediates Blood, December 1, 2004; 104(12): 3655 - 3663. [Abstract] [Full Text] [PDF]

				E. Derudder, E. Dejardin, L. L. Pritchard, D. R. Green, M. Korner, and V. Baud RelB/p50 Dimers Are Differentially Regulated by Tumor Necrosis Factor-{alpha} and Lymphotoxin-{beta} Receptor Activation: CRITICAL ROLES FOR p100 J. Biol. Chem., June 20, 2003; 278(26): 23278 - 23284. [Abstract] [Full Text] [PDF]

				M. Koyama, S. S. Spicer, and B. A. Schulte Distribution of I{kappa}B Proteins in Gastric Mucosa and Other Organs of Mouse and Gerbil J. Histochem. Cytochem., February 1, 2000; 48(2): 191 - 200. [Abstract] [Full Text]

				R. Y. Liu, C. Fan, N. E. Olashaw, X. Wang, and K. S. Zuckerman Tumor Necrosis Factor-alpha -induced Proliferation of Human Mo7e Leukemic Cells Occurs via Activation of Nuclear Factor kappa B Transcription Factor J. Biol. Chem., May 14, 1999; 274(20): 13877 - 13885. [Abstract] [Full Text] [PDF]

				D. C. St. Louis, J. B. Woodcock, G. Fransozo, P. J. Blair, L. M. Carlson, M. Murillo, M. R. Wells, A. J. Williams, D. S. Smoot, S. Kaushal, et al. Evidence for Distinct Intracellular Signaling Pathways in CD34+ Progenitor to Dendritic Cell Differentiation from a Human Cell Line Model J. Immunol., March 15, 1999; 162(6): 3237 - 3248. [Abstract] [Full Text] [PDF]

				T. A. Davis, A. A. Saini, P. J. Blair, B. L. Levine, N. Craighead, D. M. Harlan, C. H. June, and K. P. Lee Phorbol Esters Induce Differentiation of Human CD34+ Hemopoietic Progenitors to Dendritic Cells: Evidence for Protein Kinase C-Mediated Signaling J. Immunol., April 15, 1998; 160(8): 3689 - 3697. [Abstract] [Full Text] [PDF]

				N. J. Solan, H. Miyoshi, E. M. Carmona, G. D. Bren, and C. V. Paya RelB Cellular Regulation and Transcriptional Activity Are Regulated by p100 J. Biol. Chem., January 4, 2002; 277(2): 1405 - 1418. [Abstract] [Full Text] [PDF]