| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
J Biol Chem, Vol. 273, Issue 14, 7906-7910, April 3, 1998
From the Departments of Medicine and Microbiology-Immunology,
University of California, San Francisco, California 94143-0711
The recent identification of the Vzg-1/Edg2
protein as a functional G protein-coupled receptor for lysophosphatidic
acid (LPA) has allowed a sequence-based search for new genes that may
encode novel subtypes of LPA receptors. A human cDNA encoding a G
protein-coupled receptor, designated Edg4, was identified by searching
the GenBankTM for homologs of the human Edg2 LPA receptor. The Edg4
protein is 46% identical and 72% similar in amino acid sequence to
human Edg2. When overexpressed in Jurkat T cells, the Edg4 protein
mediated LPA-induced activation of a serum response element reporter
gene with LPA concentration dependence (EC50 of 10 nM) and specificity. This LPA-induced reporter gene
activation could be partially inhibited by pretreatment with pertussis
toxin or C3 exoenzyme, suggesting requirements for both a
Gi protein and Rho GTPase. Overexpression of Edg4 in Jurkat
cells also led to increases in specific binding sites for
[3H]LPA. Northern blots revealed that two
edg4 mRNA transcripts of 1.8 and 8 kilobases are
distributed very differently from edg2 mRNAs in adult
human tissues and several cancer cell lines. The existence and
distinctive tissue expression of structurally different subtypes of LPA
receptors may provide one basis for tissue-specific functions and
permit independent regulation of each subtype of LPA receptor.
This article has been cited by other articles:
|
|
 |
|
  K. M. Kassel, P. R. Dodmane, N. A. Schulte, and M. L. Toews Lysophosphatidic Acid Induces Rapid and Sustained Decreases in Epidermal Growth Factor Receptor Binding via Different Signaling Pathways in BEAS-2B Airway Epithelial Cells J. Pharmacol. Exp. Ther., June 1, 2008; 325(3): 809 - 817. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 W. J. Valentine, J. I. Fells, D. H. Perygin, S. Mujahid, K. Yokoyama, Y. Fujiwara, R. Tsukahara, J. R. Van Brocklyn, A. L. Parrill, and G. Tigyi Subtype-specific Residues Involved in Ligand Activation of the Endothelial Differentiation Gene Family Lysophosphatidic Acid Receptors J. Biol. Chem., May 2, 2008; 283(18): 12175 - 12187. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. M. Murph, J. Hurst-Kennedy, V. Newton, D. N. Brindley, and H. Radhakrishna Lysophosphatidic Acid Decreases the Nuclear Localization and Cellular Abundance of the p53 Tumor Suppressor in A549 Lung Carcinoma Cells Mol. Cancer Res., November 1, 2007; 5(11): 1201 - 1211. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. M. Kassel, N. A. Schulte, S. M. Parker, A. D. Lanik, and M. L. Toews Lysophosphatidic Acid Decreases Epidermal Growth Factor Receptor Binding in Airway Epithelial Cells J. Pharmacol. Exp. Ther., October 1, 2007; 323(1): 109 - 118. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. E. Horak, J. H. Lee, A. G. Elkahloun, M. Boissan, S. Dumont, T. K. Maga, S. Arnaud-Dabernat, D. Palmieri, W. G. Stetler-Stevenson, M.-L. Lacombe, et al. Nm23-H1 Suppresses Tumor Cell Motility by Down-regulating the Lysophosphatidic Acid Receptor EDG2 Cancer Res., August 1, 2007; 67(15): 7238 - 7246. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Zhang, A. Bialkowska, R. Rusovici, S. Chanchevalap, H. Shim, J. P. Katz, V. W. Yang, and C. C. Yun Lysophosphatidic Acid Facilitates Proliferation of Colon Cancer Cells via Induction of Kruppel-like Factor 5 J. Biol. Chem., May 25, 2007; 282(21): 15541 - 15549. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C.-W. Lee, R. Rivera, A. E. Dubin, and J. Chun LPA4/GPR23 Is a Lysophosphatidic Acid (LPA) Receptor Utilizing Gs-, Gq/Gi-mediated Calcium Signaling and G12/13-mediated Rho Activation J. Biol. Chem., February 16, 2007; 282(7): 4310 - 4317. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K.-P. Xu, J. Yin, and F.-S. X. Yu Lysophosphatidic Acid Promoting Corneal Epithelial Wound Healing by Transactivation of Epidermal Growth Factor Receptor Invest. Ophthalmol. Vis. Sci., February 1, 2007; 48(2): 636 - 643. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Murph, T. Tanaka, S. Liu, and G. B. Mills Of Spiders and Crabs: The Emergence of Lysophospholipids and Their Metabolic Pathways as Targets for Therapy in Cancer. Clin. Cancer Res., November 15, 2006; 12(22): 6598 - 6602. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Lee, S. Y. Park, E. K. Lee, C. G. Park, H. C. Chung, S. Y. Rha, Y. K. Kim, G.-U. Bae, B. K. Kim, J.-W. Han, et al. Activation of Hypoxia-Inducible Factor-1{alpha} Is Necessary for Lysophosphatidic Acid-Induced Vascular Endothelial Growth Factor Expression. Clin. Cancer Res., November 1, 2006; 12(21): 6351 - 6358. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C.-W. Lee, R. Rivera, S. Gardell, A. E. Dubin, and J. Chun GPR92 as a New G12/13- and Gq-coupled Lysophosphatidic Acid Receptor That Increases cAMP, LPA5 J. Biol. Chem., August 18, 2006; 281(33): 23589 - 23597. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. Kishi, S. Okudaira, M. Tanaka, K. Hama, D. Shida, J. Kitayama, T. Yamori, J. Aoki, T. Fujimaki, and H. Arai Autotaxin Is Overexpressed in Glioblastoma Multiforme and Contributes to Cell Motility of Glioblastoma by Converting Lysophosphatidylcholine TO Lysophosphatidic Acid J. Biol. Chem., June 23, 2006; 281(25): 17492 - 17500. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Boucharaba, C.-M. Serre, J. Guglielmi, J.-C. Bordet, P. Clezardin, and O. Peyruchaud The type 1 lysophosphatidic acid receptor is a target for therapy in bone metastases PNAS, June 20, 2006; 103(25): 9643 - 9648. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. S. Park, H.-Y. Lee, M.-K. Kim, E. H. Shin, S. H. Jo, S. D. Kim, D.-S. Im, and Y.-S. Bae Lysophosphatidylserine Stimulates L2071 Mouse Fibroblast Chemotactic Migration via a Process Involving Pertussis Toxin-Sensitive Trimeric G-Proteins Mol. Pharmacol., March 1, 2006; 69(3): 1066 - 1073. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. A. Lin and J. A. Boyce IL-4 Regulates MEK Expression Required for Lysophosphatidic Acid-Mediated Chemokine Generation by Human Mast Cells J. Immunol., October 15, 2005; 175(8): 5430 - 5438. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. Fujiwara, V. Sardar, A. Tokumura, D. Baker, K. Murakami-Murofushi, A. Parrill, and G. Tigyi Identification of Residues Responsible for Ligand Recognition and Regioisomeric Selectivity of Lysophosphatidic Acid Receptors Expressed in Mammalian Cells J. Biol. Chem., October 14, 2005; 280(41): 35038 - 35050. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. C. Yun, H. Sun, D. Wang, R. Rusovici, A. Castleberry, R. A. Hall, and H. Shim LPA2 receptor mediates mitogenic signals in human colon cancer cells Am J Physiol Cell Physiol, July 1, 2005; 289(1): C2 - C11. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. T. Budnik and B. Brunswig-Spickenheier Differential effects of lysolipids on steroid synthesis in cells expressing endogenous LPA2 receptor J. Lipid Res., May 1, 2005; 46(5): 930 - 941. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Yang, W. W. Zhong, N. Srivastava, A. Slavin, J. Yang, T. Hoey, and S. An G protein-coupled lysophosphatidic acid receptors stimulate proliferation of colon cancer cells through the {beta}-catenin pathway PNAS, April 26, 2005; 102(17): 6027 - 6032. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. Itagaki, K. B. Kannan, and C. J. Hauser Lysophosphatidic acid triggers calcium entry through a non-store-operated pathway in human neutrophils J. Leukoc. Biol., February 1, 2005; 77(2): 181 - 189. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Bagga, K. S. Price, D. A. Lin, D. S. Friend, K. F. Austen, and J. A. Boyce Lysophosphatidic acid accelerates the development of human mast cells Blood, December 15, 2004; 104(13): 4080 - 4087. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Y. Xing, S. H. Ganji, J. W. Noh, and V. S. Kamanna Cell density-dependent expression of EDG family receptors and mesangial cell proliferation: role in lysophosphatidic acid-mediated cell growth Am J Physiol Renal Physiol, December 1, 2004; 287(6): F1250 - F1257. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Y.-S. Oh, N. W. Jo, J. W. Choi, H. S. Kim, S.-W. Seo, K.-O. Kang, J.-I. Hwang, K. Heo, S.-H. Kim, Y.-H. Kim, et al. NHERF2 Specifically Interacts with LPA2 Receptor and Defines the Specificity and Efficiency of Receptor-Mediated Phospholipase C-{beta}3 Activation Mol. Cell. Biol., June 1, 2004; 24(11): 5069 - 5079. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Hama, J. Aoki, M. Fukaya, Y. Kishi, T. Sakai, R. Suzuki, H. Ohta, T. Yamori, M. Watanabe, J. Chun, et al. Lysophosphatidic Acid and Autotaxin Stimulate Cell Motility of Neoplastic and Non-neoplastic Cells through LPA1 J. Biol. Chem., April 23, 2004; 279(17): 17634 - 17639. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Xu, Y.-J. Lai, W.-C. Lin, and F.-T. Lin TRIP6 Enhances Lysophosphatidic Acid-induced Cell Migration by Interacting with the Lysophosphatidic Acid 2 Receptor J. Biol. Chem., March 12, 2004; 279(11): 10459 - 10468. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D.-S. Im Discovery of new G protein-coupled receptors for lipid mediators J. Lipid Res., March 1, 2004; 45(3): 410 - 418. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Hiramatsu, H. Sonoda, Y. Takanezawa, R. Morikawa, M. Ishida, K. Kasahara, Y. Sanai, R. Taguchi, J. Aoki, and H. Arai Biochemical and Molecular Characterization of Two Phosphatidic Acid-selective Phospholipase A1s, mPA-PLA1{alpha} and mPA-PLA1{beta} J. Biol. Chem., December 5, 2003; 278(49): 49438 - 49447. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Ohta, K. Sato, N. Murata, A. Damirin, E. Malchinkhuu, J. Kon, T. Kimura, M. Tobo, Y. Yamazaki, T. Watanabe, et al. Ki16425, a Subtype-Selective Antagonist for EDG-Family Lysophosphatidic Acid Receptors Mol. Pharmacol., October 1, 2003; 64(4): 994 - 1005. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Stahle, C. Veit, U. Bachfischer, K. Schierling, B. Skripczynski, A. Hall, P. Gierschik, and K. Giehl Mechanisms in LPA-induced tumor cell migration: critical role of phosphorylated ERK J. Cell Sci., September 15, 2003; 116(18): 3835 - 3846. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Takeya, E. C. Gabazza, S. Aoki, H. Ueno, and K. Suzuki Synergistic effect of sphingosine 1-phosphate on thrombin-induced tissue factor expression in endothelial cells Blood, September 1, 2003; 102(5): 1693 - 1700. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Noguchi, S. Ishii, and T. Shimizu Identification of p2y9/GPR23 as a Novel G Protein-coupled Receptor for Lysophosphatidic Acid, Structurally Distant from the Edg Family J. Biol. Chem., July 3, 2003; 278(28): 25600 - 25606. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Y.-L. Hu, C. Albanese, R. G. Pestell, and R. B. Jaffe Dual Mechanisms for Lysophosphatidic Acid Stimulation of Human Ovarian Carcinoma Cells J Natl Cancer Inst, May 21, 2003; 95(10): 733 - 740. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Shida, J. Kitayama, H. Yamaguchi, Y. Okaji, N. H. Tsuno, T. Watanabe, Y. Takuwa, and H. Nagawa Lysophosphatidic Acid (LPA) Enhances the Metastatic Potential of Human Colon Carcinoma DLD1 Cells through LPA1 Cancer Res., April 1, 2003; 63(7): 1706 - 1711. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. Hasegawa, J. R. Erickson, G. J. Goddard, S. Yu, S. Liu, K. W. Cheng, A. Eder, K. Bandoh, J. Aoki, R. Jarosz, et al. Identification of a Phosphothionate Analogue of Lysophosphatidic Acid (LPA) as a Selective Agonist of the LPA3 Receptor J. Biol. Chem., March 28, 2003; 278(14): 11962 - 11969. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. L. Tanyi, A. J. Morris, J. K. Wolf, X. Fang, Y. Hasegawa, R. Lapushin, N. Auersperg, Y. J. Sigal, R. A. Newman, E. A. Felix, et al. The Human Lipid Phosphate Phosphatase-3 Decreases the Growth, Survival, and Tumorigenesis of Ovarian Cancer Cells: Validation of the Lysophosphatidic Acid Signaling Cascade as a Target for Therapy in Ovarian Cancer Cancer Res., March 1, 2003; 63(5): 1073 - 1082. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Yuan, L. W. Slice, J. Gu, and E. Rozengurt Cooperation of Gq, Gi, and G12/13 in Protein Kinase D Activation and Phosphorylation Induced by Lysophosphatidic Acid J. Biol. Chem., February 7, 2003; 278(7): 4882 - 4891. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M.-Z. Cui, G. Zhao, A. L. Winokur, E. Laag, J. R. Bydash, M. S. Penn, G. M. Chisolm, and X. Xu Lysophosphatidic Acid Induction of Tissue Factor Expression in Aortic Smooth Muscle Cells Arterioscler. Thromb. Vasc. Biol., February 1, 2003; 23(2): 224 - 230. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Aoki, A. Taira, Y. Takanezawa, Y. Kishi, K. Hama, T. Kishimoto, K. Mizuno, K. Saku, R. Taguchi, and H. Arai Serum Lysophosphatidic Acid Is Produced through Diverse Phospholipase Pathways J. Biol. Chem., December 6, 2002; 277(50): 48737 - 48744. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Sugiura, S. Nakane, S. Kishimoto, K. Waku, Y. Yoshioka, and A. Tokumura Lysophosphatidic acid, a growth factor-like lipid, in the saliva J. Lipid Res., December 1, 2002; 43(12): 2049 - 2055. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. J. A. Contos, I. Ishii, N. Fukushima, M. A. Kingsbury, X. Ye, S. Kawamura, J. H. Brown, and J. Chun Characterization of lpa2 (Edg4) and lpa1/lpa2 (Edg2/Edg4) Lysophosphatidic Acid Receptor Knockout Mice: Signaling Deficits without Obvious Phenotypic Abnormality Attributable to lpa2 Mol. Cell. Biol., October 1, 2002; 22(19): 6921 - 6929. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Wang, L. D. Carbone, and M. A. Watsky Receptor-Mediated Activation of a Cl- Current by LPA and S1P in Cultured Corneal Keratocytes Invest. Ophthalmol. Vis. Sci., October 1, 2002; 43(10): 3202 - 3208. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Sonoda, J. Aoki, T. Hiramatsu, M. Ishida, K. Bandoh, Y. Nagai, R. Taguchi, K. Inoue, and H. Arai A Novel Phosphatidic Acid-selective Phospholipase A1 That Produces Lysophosphatidic Acid J. Biol. Chem., September 6, 2002; 277(37): 34254 - 34263. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 N. Fukushima, I. Ishii, Y. Habara, C. B. Allen, and J. Chun Dual Regulation of Actin Rearrangement through Lysophosphatidic Acid Receptor in Neuroblast Cell Lines: Actin Depolymerization by Ca2+-alpha -Actinin and Polymerization by Rho Mol. Biol. Cell, August 1, 2002; 13(8): 2692 - 2705. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Umezu-Goto, Y. Kishi, A. Taira, K. Hama, N. Dohmae, K. Takio, T. Yamori, G. B. Mills, K. Inoue, J. Aoki, et al. Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production J. Cell Biol., July 22, 2002; 158(2): 227 - 233. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
W. B. Thoreson, J. S. Ryan, C. Shi, M. E. Kelly, E. J. Bryson, M. L. Toews, T. L. Ediger, and D. M. Chacko Lysophosphatidic Acid Receptor Signaling in Mammalian Retinal Pigment Epithelial Cells Invest. Ophthalmol. Vis. Sci., July 1, 2002; 43(7): 2450 - 2461. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. KOHNO, A. WADA, and Y. IGARASHI N-Glycans of sphingosine 1-phosphate receptor Edg-1 regulate ligand-induced receptor internalization FASEB J, July 1, 2002; 16(9): 983 - 992. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Lu, Y.-j. Xiao, L. M. Baudhuin, G. Hong, and Y. Xu Role of ether-linked lysophosphatidic acids in ovarian cancer cells J. Lipid Res., March 1, 2002; 43(3): 463 - 476. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Tokumura, Y. Kanaya, M. Kitahara, M. Miyake, Y. Yoshioka, and K. Fukuzawa Increased formation of lysophosphatidic acids by lysophospholipase D in serum of hypercholesterolemic rabbits J. Lipid Res., February 1, 2002; 43(2): 307 - 315. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. L. Ediger, B. L. Danforth, and M. L. Toews Lysophosphatidic acid upregulates the epidermal growth factor receptor in human airway smooth muscle cells Am J Physiol Lung Cell Mol Physiol, January 1, 2002; 282(1): L91 - L98. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Tigyi Selective Ligands for Lysophosphatidic Acid Receptor Subtypes: Gaining Control over the Endothelial Differentiation Gene Family Mol. Pharmacol., December 1, 2001; 60(6): 1161 - 1164. [Full Text] [PDF]
|
|
|
|
|
|
C. E. Heise, W. L. Santos, A. M. Schreihofer, B. H. Heasley, Y. V. Mukhin, T. L. Macdonald, and K. R. Lynch Activity of 2-Substituted Lysophosphatidic Acid (LPA) Analogs at LPA Receptors: Discovery of a LPA1/LPA3 Receptor Antagonist Mol. Pharmacol., December 1, 2001; 60(6): 1173 - 1180. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. Y. Sautin, J. M. Crawford, and S. I. Svetlov Enhancement of survival by LPA via Erk1/Erk2 and PI 3-kinase/Akt pathways in a murine hepatocyte cell line Am J Physiol Cell Physiol, December 1, 2001; 281(6): C2010 - C2019. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. Hla, M.-J. Lee, N. Ancellin, J. H. Paik, and M. J. Kluk Lysophospholipids--Receptor Revelations Science, November 30, 2001; 294(5548): 1875 - 1878. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Tao, C. C. Malbon, and H.-y. Wang Galpha i2 Enhances Insulin Signaling via Suppression of Protein-tyrosine Phosphatase 1B J. Biol. Chem., October 19, 2001; 276(43): 39705 - 39712. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y.-L. Hu, M.-K. Tee, E. J. Goetzl, N. Auersperg, G. B. Mills, N. Ferrara, and R. B. Jaffe Lysophosphatidic Acid Induction of Vascular Endothelial Growth Factor Expression in Human Ovarian Cancer Cells J Natl Cancer Inst, May 16, 2001; 93(10): 762 - 767. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. J. A. Contos, I. Ishii, and J. Chun Lysophosphatidic Acid Receptors Mol. Pharmacol., April 13, 2001; 58(6): 1188 - 1196. [Abstract] [Full Text]
|
|
|
|
|
|
D. A. Fishman, Y. Liu, S. M. Ellerbroek, and M. S. Stack Lysophosphatidic Acid Promotes Matrix Metalloproteinase (MMP) Activation and MMP-dependent Invasion in Ovarian Cancer Cells Cancer Res., April 1, 2001; 61(7): 3194 - 3199. [Abstract] [Full Text]
|
|
|
|
 |
|
 A. Grey, T. Banovic, D. Naot, B. Hill, K. Callon, I. Reid, and J. Cornish Lysophosphatidic Acid Is an Osteoblast Mitogen Whose Proliferative Actions Involve Gi Proteins and Protein Kinase C, But Not P42/44 Mitogen-Activated Protein Kinases Endocrinology, March 1, 2001; 142(3): 1098 - 1106. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. English, J. G.N. Garcia, and D.N. Brindley Platelet-released phospholipids link haemostasis and angiogenesis Cardiovasc Res, February 16, 2001; 49(3): 588 - 599. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. Zheng, Y. Kong, and E. J. Goetzl Lysophosphatidic Acid Receptor-Selective Effects on Jurkat T Cell Migration Through a Matrigel Model Basement Membrane J. Immunol., February 15, 2001; 166(4): 2317 - 2322. [Abstract] [Full Text] [PDF]
|
