HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Bazhenova, E. N. Articles by Saris, N.-E. L. Search for Related Content PubMed PubMed Citation Articles by Bazhenova, E. N. Articles by Saris, N.-E. L. Social Bookmarking                      What's this?

J Biol Chem, Vol. 273, Issue 8, 4372-4377, February 20, 1998

Characterization of a High Capacity Calcium Transport System in Mitochondria of the Yeast Endomyces magnusii

Elena N. Bazhenova, Yulia I. Deryabina, Ove Eriksson^§, Renata A. Zvyagilskaya, and Nils-Erik L. Saris^§

From the  Laboratory of Biological Oxidation, Bach Institute of Biochemistry, Russian Academy of Sciences, 117071 Moscow, Russia and the ^§ Department of Medical Chemistry, Institute of Biomedicine, University of Helsinki, FIN-00014 Helsinki, Finland

The Ca²⁺ transport system of Endomyces magnusii mitochondria has been shown previously to be activated by spermine. Here we report it to be regulated also by low, physiological ADP concentrations, by the intramitochondrial NADH/NAD⁺ ratio, and by Ca²⁺ ions. The combination of all these physiological modulators induced high initial rates of Ca²⁺ uptake and high Ca²⁺-buffering capacity of yeast mitochondria, enabling them to lower the medium [Ca²⁺] to ~0.2 µM. The mechanisms of stimulation by these agents are discussed.

CiteULike

Complore

Connotea

Del.icio.us

Digg

Reddit

Technorati

This article has been cited by other articles:

				A. I. Pozniakovsky, D. A. Knorre, O. V. Markova, A. A. Hyman, V. P. Skulachev, and F. F. Severin Role of mitochondria in the pheromone- and amiodarone-induced programmed death of yeast J. Cell Biol., January 17, 2005; 168(2): 257 - 269. [Abstract] [Full Text] [PDF]

				Y. I. Deryabina, E. N. Bazhenova, N.-E. L. Saris, and R. A. Zvyagilskaya Ca2+ Efflux in Mitochondria from the Yeast Endomyces magnusii J. Biol. Chem., December 14, 2001; 276(51): 47801 - 47806. [Abstract] [Full Text] [PDF]