| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
J Biol Chem, Vol. 274, Issue 16, 11431-11438, April 16, 1999
,,,,, and
From the The lecticans are a group of chondroitin sulfate
proteoglycans characterized by the presence of C-type lectin domains.
Despite the suggestion that their lectin domains interact with
carbohydrate ligands, the identity of such ligands has not been
elucidated. We previously showed that brevican, a nervous
system-specific lectican, binds the surface of B28 glial cells (Yamada,
H., Fredette, B., Shitara, K., Hagihara, K., Miura, R., Ranscht, B.,
Stallcup, W. B., and Yamaguchi, Y. (1997) J. Neurosci. 17, 7784-7795). In this paper, we demonstrate that two
classes of sulfated glycolipids, sulfatides and HNK-1-reactive
sulfoglucuronylglycolipids (SGGLs), act as cell surface receptors for
brevican. The lectin domain of brevican binds sulfatides and SGGLs in a
calcium-dependent manner as expected of a C-type lectin
domain. Intact, full-length brevican also binds both sulfatides and
SGGLs. The lectin domain immobilized as a substrate supports adhesion
of cells expressing SGGLs or sulfatides, which was inhibited by
monoclonal antibodies against these glycolipids or by treatment of the
substrate with SGGLs or sulfatides. Our findings demonstrate that the
interaction between the lectin domains of lecticans and sulfated
glycolipids comprises a novel cell substrate recognition system, and
suggest that lecticans in extracellular matrices serve as substrate for adhesion and migration of cells expressing these glycolipids in vivo.
Burnham Institute, La Jolla, California
92037 and the ¶ Department of Pharmacology and Neuroscience,
Johns Hopkins University School of Medicine,
Baltimore, Maryland 21205
This article has been cited by other articles:
|
|
 |
|
  Z. V. Popovic, R. Sandhoff, T. P. Sijmonsma, S. Kaden, R. Jennemann, E. Kiss, E. Tone, F. Autschbach, N. Platt, E. Malle, et al. Sulfated Glycosphingolipid as Mediator of Phagocytosis: SM4s Enhances Apoptotic Cell Clearance and Modulates Macrophage Activity J. Immunol., November 15, 2007; 179(10): 6770 - 6782. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. R. Dunning, M. Lane, H. M. Brown, C. Yeo, R. L. Robker, and D. L. Russell Altered composition of the cumulus-oocyte complex matrix during in vitro maturation of oocytes Hum. Reprod., November 1, 2007; 22(11): 2842 - 2850. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 W. Sheng, G. Wang, D. P. La Pierre, J. Wen, Z. Deng, C.-K. A. Wong, D. Y. Lee, and B. B. Yang Versican Mediates Mesenchymal-Epithelial Transition Mol. Biol. Cell, April 1, 2006; 17(4): 2009 - 2020. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. M. Day, A. I. Olin, A. D. Murdoch, A. Canfield, T. Sasaki, R. Timpl, T. E. Hardingham, and A. Aspberg Alternative Splicing in the Aggrecan G3 Domain Influences Binding Interactions with Tenascin-C and Other Extracellular Matrix Proteins J. Biol. Chem., March 26, 2004; 279(13): 12511 - 12518. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. V. Chandrasekaran, S. S. Lakhaman, R. Chawda, C. F. Piskorz, S. Neelamegham, and K. L. Matta Identification of Physiologically Relevant Substrates for Cloned Gal: 3-O-Sulfotransferases (Gal3STs): DISTINCT HIGH AFFINITY OF Gal3ST-2 and LS180 SULFOTRANSFERASE FOR THE GLOBO H BACKBONE, Gal3ST-3 FOR N-GLYCAN MULTITERMINAL Gal{beta}1,4GlcNAc{beta} UNITS AND 6-SULFOGal{beta}1,4GlcNAc{beta}, AND Gal3ST-4 FOR THE MUCIN CORE-2 TRISACCHARIDE J. Biol. Chem., March 12, 2004; 279(11): 10032 - 10041. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. L. Russell, K. M. H. Doyle, S. A. Ochsner, J. D. Sandy, and J. S. Richards Processing and Localization of ADAMTS-1 and Proteolytic Cleavage of Versican during Cumulus Matrix Expansion and Ovulation J. Biol. Chem., October 24, 2003; 278(43): 42330 - 42339. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Mikami, S. Mizumoto, N. Kago, H. Kitagawa, and K. Sugahara Specificities of Three Distinct Human Chondroitin/Dermatan N-Acetylgalactosamine 4-O-Sulfotransferases Demonstrated Using Partially Desulfated Dermatan Sulfate as an Acceptor: IMPLICATION OF DIFFERENTIAL ROLES IN DERMATAN SULFATE BIOSYNTHESIS J. Biol. Chem., September 19, 2003; 278(38): 36115 - 36127. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. S. Viapiano, R. T. Matthews, and S. Hockfield A Novel Membrane-associated Glycovariant of BEHAB/Brevican Is Up-regulated during Rat Brain Development and in a Rat Model of Invasive Glioma J. Biol. Chem., August 29, 2003; 278(35): 33239 - 33247. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Y. Katsu, D. B. Lubahn, and T. Iguchi Expression of a Novel C-Type Lectin in the Mouse Vagina Endocrinology, June 1, 2003; 144(6): 2597 - 2605. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. P. Spicer, A. Joo, and R. A. Bowling Jr. A Hyaluronan Binding Link Protein Gene Family Whose Members Are Physically Linked Adjacent to Chrondroitin Sulfate Proteoglycan Core Protein Genes: THE MISSING LINKS J. Biol. Chem., May 30, 2003; 278(23): 21083 - 21091. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. M. Burdick, J. M. McCaffery, Y. S. Kim, B. S. Bochner, and K. Konstantopoulos Colon carcinoma cell glycolipids, integrins, and other glycoproteins mediate adhesion to HUVECs under flow Am J Physiol Cell Physiol, April 1, 2003; 284(4): C977 - C987. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. Brakebusch, C. I. Seidenbecher, F. Asztely, U. Rauch, H. Matthies, H. Meyer, M. Krug, T. M. Bockers, X. Zhou, M. R. Kreutz, et al. Brevican-Deficient Mice Display Impaired Hippocampal CA1 Long-Term Potentiation but Show No Obvious Deficits in Learning and Memory Mol. Cell. Biol., November 1, 2002; 22(21): 7417 - 7427. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. A. Asher, D. A. Morgenstern, M. C. Shearer, K. H. Adcock, P. Pesheva, and J. W. Fawcett Versican Is Upregulated in CNS Injury and Is a Product of Oligodendrocyte Lineage Cells J. Neurosci., March 15, 2002; 22(6): 2225 - 2236. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. L. Nutt, C. A. Zerillo, G. M. Kelly, and S. Hockfield Brain Enriched Hyaluronan Binding (BEHAB)/Brevican Increases Aggressiveness of CNS-1 Gliomas in Lewis Rats Cancer Res., October 1, 2001; 61(19): 7056 - 7059. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
X.-H. Zhou, C. Brakebusch, H. Matthies, T. Oohashi, E. Hirsch, M. Moser, M. Krug, C. I. Seidenbecher, T. M. Boeckers, U. Rauch, et al. Neurocan Is Dispensable for Brain Development Mol. Cell. Biol., September 1, 2001; 21(17): 5970 - 5978. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. E. Bandtlow and D. R. Zimmermann Proteoglycans in the Developing Brain: New Conceptual Insights for Old Proteins Physiol Rev, October 1, 2000; 80(4): 1267 - 1290. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. Li, T.-C. Leung, S. Hoffman, J. Balsamo, and J. Lilien Coordinate Regulation of Cadherin and Integrin Function by the Chondroitin Sulfate Proteoglycan Neurocan J. Cell Biol., June 12, 2000; 149(6): 1275 - 1288. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. C. Reidling, M. A. Miller, and R. E. Steele Sweet Tooth, a Novel Receptor Protein-tyrosine Kinase with C-type Lectin-like Extracellular Domains J. Biol. Chem., March 31, 2000; 275(14): 10323 - 10330. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D Perissinotto, P Iacopetti, I Bellina, R Doliana, A Colombatti, Z Pettway, M Bronner-Fraser, T Shinomura, K Kimata, M Morgelin, et al. Avian neural crest cell migration is diversely regulated by the two major hyaluronan-binding proteoglycans PG-M/versican and aggrecan Development, January 7, 2000; 127(13): 2823 - 2842. [Abstract] [PDF]
|
|
|
|
 |
|
 M Schmalfeldt, C. Bandtlow, M. Dours-Zimmermann, K. Winterhalter, and D. Zimmermann Brain derived versican V2 is a potent inhibitor of axonal growth J. Cell Sci., January 3, 2000; 113(5): 807 - 816. [Abstract] [PDF]
|
|
|
|
|
|
M. N. Fukuda, C. Ohyama, K. Lowitz, O. Matsuo, R. Pasqualini, E. Ruoslahti, and M. Fukuda A Peptide Mimic of E-Selectin Ligand Inhibits Sialyl Lewis X-dependent Lung Colonization of Tumor Cells Cancer Res., January 1, 2000; 60(2): 450 - 456. [Abstract] [Full Text]
|
|
|
|
|
|
K Prydz and K. Dalen Synthesis and sorting of proteoglycans J. Cell Sci., January 1, 2000; 113(2): 193 - 205. [Abstract] [PDF]
|
|
|
|
|
|
J. M. Day, A. D. Murdoch, and T. E. Hardingham The Folded Protein Modules of the C-terminal G3 Domain of Aggrecan Can Each Facilitate the Translocation and Secretion of the Extended Chondroitin Sulfate Attachment Sequence J. Biol. Chem., December 31, 1999; 274(53): 38107 - 38111. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Fukuda, N. Hiraoka, and J.-C. Yeh C-Type Lectins and Sialyl Lewis X Oligosaccharides: Versatile Roles in Cell-Cell Interaction J. Cell Biol., November 1, 1999; 147(3): 467 - 470. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. P. Niederost, D. R. Zimmermann, M. E. Schwab, and C. E. Bandtlow Bovine CNS Myelin Contains Neurite Growth-Inhibitory Activity Associated with Chondroitin Sulfate Proteoglycans J. Neurosci., October 15, 1999; 19(20): 8979 - 8989. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Kawashima, M. Hirose, J. Hirose, D. Nagakubo, A. H. K. Plaas, and M. Miyasaka Binding of a Large Chondroitin Sulfate/Dermatan Sulfate Proteoglycan, Versican, to L-selectin, P-selectin, and CD44 J. Biol. Chem., November 3, 2000; 275(45): 35448 - 35456. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Nakamura, Y. Fujii, I. Inoki, K. Sugimoto, K. Tanzawa, H. Matsuki, R. Miura, Y. Yamaguchi, and Y. Okada Brevican Is Degraded by Matrix Metalloproteinases and Aggrecanase-1 (ADAMTS4) at Different Sites J. Biol. Chem., December 1, 2000; 275(49): 38885 - 38890. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. I. Olin, M. Morgelin, T. Sasaki, R. Timpl, D. Heinegard, and A. Aspberg The Proteoglycans Aggrecan and Versican Form Networks with Fibulin-2 through Their Lectin Domain Binding J. Biol. Chem., January 5, 2001; 276(2): 1253 - 1261. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Zhou, V. Kartsogiannis, Y. S. Hu, J. Elliott, J. M. W. Quinn, W. J. McKinstry, M. T. Gillespie, and K. W. Ng A Novel Osteoblast-derived C-type Lectin That Inhibits Osteoclast Formation J. Biol. Chem., April 27, 2001; 276(18): 14916 - 14923. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. R. Henion, D. Zhou, D. P. Wolfer, F. B. Jungalwala, and T. Hennet Cloning of a Mouse beta 1,3 N-Acetylglucosaminyltransferase GlcNAc(beta 1,3)Gal(beta 1,4)Glc-ceramide Synthase Gene Encoding the Key Regulator of Lacto-series Glycolipid Biosynthesis J. Biol. Chem., August 3, 2001; 276(32): 30261 - 30269. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| All ASBMB Journals | Molecular and Cellular Proteomics |
| Journal of Lipid Research | ASBMB Today |
