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J Biol Chem, Vol. 274, Issue 20, 14170-14175, May 14, 1999
From the A new lipoprotein lipase-like gene has been
cloned from endothelial cells through a subtraction methodology aimed
at characterizing genes that are expressed with in vitro
differentiation of this cell type. The conceptual endothelial
cell-derived lipase protein contains 500 amino acids, including an
18-amino acid hydrophobic signal sequence, and is 44% identical to
lipoprotein lipase and 41% identical to hepatic lipase. Comparison of
primary sequence to that of lipoprotein and hepatic lipase reveals
conservation of the serine, aspartic acid, and histidine catalytic
residues as well as the 10 cysteine residues involved in disulfide bond formation. Expression was identified in cultured human umbilical vein
endothelial cells, human coronary artery endothelial cells, and murine
endothelial-like yolk sac cells by Northern blot. In addition, Northern
blot and in situ hybridization analysis revealed expression
of the endothelial-derived lipase in placenta, liver, lung, ovary,
thyroid gland, and testis. A c-Myc-tagged protein secreted from
transfected COS7 cells had phospholipase A1 activity but no
triglyceride lipase activity. Its tissue-restricted pattern of
expression and its ability to be expressed by endothelial cells, suggests that endothelial cell-derived lipase may have unique functions
in lipoprotein metabolism and in vascular disease.
Cloning of a Unique Lipase from Endothelial Cells Extends the
Lipase Gene Family
,
,,, and
Division of Cardiology, Stanford University
Medical School, Stanford, California, 94305, § Children's
Hospital Oakland Research Institute, Oakland, California 94609 and
Department of Pediatrics, University of California at San Francisco,
California 94143, ¶ Progenitor, Inc., Menlo Park, California,
94025, Palo Alto Medical Foundation, Palo Alto, California,
94301, and ** Division of Gastroenterology, Stanford University Medical
School, Stanford, California, 94305
Copyright © 1999 by The American Society for Biochemistry and Molecular Biology, Inc.
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|
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|
|
|
|
|
|
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|
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 |
|
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 |
|
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|
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