JBC Ideal method for primary cell transfection

HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Arystarkhova, E.
Right arrow Articles by Sweadner, K. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Arystarkhova, E.
Right arrow Articles by Sweadner, K. J.

J Biol Chem, Vol. 274, Issue 47, 33183-33185, November 19, 1999

COMMUNICATION
The gamma  Subunit Modulates Na+ and K+ Affinity of the Renal Na,K-ATPase

Elena Arystarkhova, Randall K. Wetzel, Natalya K. Asinovski, and Kathleen J. Sweadner

From the Laboratory of Membrane Biology, Neuroscience Center, Massachusetts General Hospital, Charlestown, Massachusetts 02129

The Na+,K+-ATPase catalyzes the active transport of ions. It has two necessary subunits, alpha  and beta , but in kidney it is also associated with a 7.4-kDa protein, the gamma  subunit. Stable transfection was used to determine the effect of gamma  on Na,K-ATPase properties. When isolated from either kidney or transfected cells, alpha beta gamma had lower affinities for both Na+ and K+ than alpha beta . A post-translational modification of gamma  selectively eliminated the effect on Na+ affinity, suggesting three configurations (alpha beta , alpha beta gamma , and alpha beta gamma *) conferring different stable properties to Na,K-ATPase. In the nephron, segment-specific differences in Na+ affinity have been reported that cannot be explained by the known alpha  and beta  subunit isoforms of Na,K-ATPase. Immunofluorescence was used to detect gamma  in rat renal cortex. Cortical ascending limb and some cortical collecting tubules lacked gamma , correlating with higher Na+ affinities in those segments reported in the literature. Selective expression in different segments of the nephron is consistent with a modulatory role for the gamma  subunit in renal physiology.

Copyright © 1999 by The American Society for Biochemistry and Molecular Biology, Inc.


This article has been cited by other articles:


Home page
 Am. J. Physiol. Renal Physiol.Home page
I. Lubarski, S. J. D. Karlish, and H. Garty
Structural and functional interactions between FXYD5 and the Na+-K+-ATPase
Am J Physiol Renal Physiol, December 1, 2007; 293(6): F1818 - F1826.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
B. Delprat, D. Schaer, S. Roy, J. Wang, J.-L. Puel, and K. Geering
FXYD6 Is a Novel Regulator of Na,K-ATPase Expressed in the Inner Ear
J. Biol. Chem., March 9, 2007; 282(10): 7450 - 7456.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Cell Physiol.Home page
E. Arystarkhova, C. Donnet, A. Munoz-Matta, S. C. Specht, and K. J. Sweadner
Multiplicity of expression of FXYD proteins in mammalian cells: dynamic exchange of phospholemman and {gamma}-subunit in response to stress
Am J Physiol Cell Physiol, March 1, 2007; 292(3): C1179 - C1191.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Cell Physiol.Home page
K. L. Lansbery, L. C. Burcea, M. L. Mendenhall, and R. W. Mercer
Cytoplasmic targeting signals mediate delivery of phospholemman to the plasma membrane
Am J Physiol Cell Physiol, May 1, 2006; 290(5): C1275 - C1286.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
M. Lindzen, K.-E. Gottschalk, M. Fuzesi, H. Garty, and S. J. D. Karlish
Structural Interactions between FXYD Proteins and Na+,K+-ATPase: {alpha}/beta/FXYD SUBUNIT STOICHIOMETRY AND CROSS-LINKING
J. Biol. Chem., March 3, 2006; 281(9): 5947 - 5955.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
I. Dostanic-Larson, J. N. Lorenz, J. W. Van Huysse, J. C. Neumann, A. E. Moseley, and J. B Lingrel
Physiological role of the {alpha}1- and {alpha}2-isoforms of the Na+-K+-ATPase and biological significance of their cardiac glycoside binding site
Am J Physiol Regulatory Integrative Comp Physiol, March 1, 2006; 290(3): R524 - R528.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Renal Physiol.Home page
K. Geering
FXYD proteins: new regulators of Na-K-ATPase
Am J Physiol Renal Physiol, February 1, 2006; 290(2): F241 - F250.
[Abstract] [Full Text] [PDF]

Home page
 Circ. Res.Home page
S. Despa, J. Bossuyt, F. Han, K. S. Ginsburg, L.-G. Jia, H. Kutchai, A. L. Tucker, and D. M. Bers
Phospholemman-Phosphorylation Mediates the {beta}-Adrenergic Effects on Na/K Pump Function in Cardiac Myocytes
Circ. Res., August 5, 2005; 97(3): 252 - 259.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
Y. A. Mahmmoud, H. Vorum, and F. Cornelius
Interaction of FXYD10 (PLMS) with Na,K-ATPase from Shark Rectal Glands: CLOSE PROXIMITY OF Cys74 OF FXYD10 TO Cys254 IN THE A DOMAIN OF THE {alpha}-SUBUNIT REVEALED BY INTERMOLECULAR THIOL CROSS-LINKING
J. Biol. Chem., July 29, 2005; 280(30): 27776 - 27782.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
D. H. Jones, T. Y. Li, E. Arystarkhova, K. J. Barr, R. K. Wetzel, J. Peng, K. Markham, K. J. Sweadner, G.-H. Fong, and G. M. Kidder
Na,K-ATPase from Mice Lacking the {gamma} Subunit (FXYD2) Exhibits Altered Na+ Affinity and Decreased Thermal Stability
J. Biol. Chem., May 13, 2005; 280(19): 19003 - 19011.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
M. Fuzesi, K.-E. Gottschalk, M. Lindzen, A. Shainskaya, B. Kuster, H. Garty, and S. J. D. Karlish
Covalent Cross-links between the {gamma} Subunit (FXYD2) and {alpha} and {beta} Subunits of Na,K-ATPase: MODELING THE {alpha}-{gamma} INTERACTION
J. Biol. Chem., May 6, 2005; 280(18): 18291 - 18301.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Biol. CellHome page
G. Crambert, C. Li, D. Claeys, and K. Geering
FXYD3 (Mat-8), a New Regulator of Na,K-ATPase
Mol. Biol. Cell, May 1, 2005; 16(5): 2363 - 2371.
[Abstract] [Full Text] [PDF]

Home page
 Physiol. Rev.Home page
M. Cereijido, R. G. Contreras, and L. Shoshani
Cell Adhesion, Polarity, and Epithelia in the Dawn of Metazoans
Physiol Rev, October 1, 2004; 84(4): 1229 - 1262.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
R. K. Wetzel, J. L. Pascoa, and E. Arystarkhova
Stress-induced Expression of the {gamma} Subunit (FXYD2) Modulates Na,K-ATPase Activity and Cell Growth
J. Biol. Chem., October 1, 2004; 279(40): 41750 - 41757.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
C. Li, A. Grosdidier, G. Crambert, J.-D. Horisberger, O. Michielin, and K. Geering
Structural and Functional Interaction Sites between Na,K-ATPase and FXYD Proteins
J. Biol. Chem., September 10, 2004; 279(37): 38895 - 38902.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
G. Crambert, C. Li, L. K. Swee, and K. Geering
FXYD7, Mapping of Functional Sites Involved in Endoplasmic Reticulum Export, Association With and Regulation of Na,K-ATPase
J. Biol. Chem., July 16, 2004; 279(29): 30888 - 30895.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
A. V. Ivanov, M. E. Gable, and A. Askari
Interaction of SDS with Na+/K+-ATPase: SDS-SOLUBILIZED ENZYME RETAINS PARTIAL STRUCTURE AND FUNCTION
J. Biol. Chem., July 9, 2004; 279(28): 29832 - 29840.
[Abstract] [Full Text] [PDF]

Home page
 HypertensionHome page
C. A. Hinojos and P. A. Doris
Altered Subcellular Distribution of Na+,K+-ATPase in Proximal Tubules in Young Spontaneously Hypertensive Rats
Hypertension, July 1, 2004; 44(1): 95 - 100.
[Abstract] [Full Text] [PDF]

Home page
 J. Physiol.Home page
V. Summa, S. M. R. Camargo, C. Bauch, M. Zecevic, and F. Verrey
Isoform specificity of human Na+,K+-ATPase localization and aldosterone regulation in mouse kidney cells
J. Physiol., March 1, 2004; 555(2): 355 - 364.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Biol. CellHome page
J. P.T. Higgins, L. Wang, N. Kambham, K. Montgomery, V. Mason, S. U. Vogelmann, K. V. Lemley, P. O. Brown, J. D. Brooks, and M. van de Rijn
Gene Expression in the Normal Adult Human Kidney Assessed by Complementary DNA Microarray
Mol. Biol. Cell, February 1, 2004; 15(2): 649 - 656.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
Y. A. Mahmmoud, G. Cramb, A. B Maunsbach, C. P. Cutler, L. Meischke, and F. Cornelius
Regulation of Na,K-ATPase by PLMS, the Phospholemman-like Protein from Shark: MOLECULAR CLONING, SEQUENCE, EXPRESSION, CELLULAR DISTRIBUTION, AND FUNCTIONAL EFFECTS OF PLMS
J. Biol. Chem., September 26, 2003; 278(39): 37427 - 37438.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Renal Physiol.Home page
A. K. Rajasekaran and S. A. Rajasekaran
Role of Na-K-ATPase in the assembly of tight junctions
Am J Physiol Renal Physiol, September 1, 2003; 285(3): F388 - F396.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Renal Physiol.Home page
R. K. Wetzel and K. J. Sweadner
Phospholemman expression in extraglomerular mesangium and afferent arteriole of the juxtaglomerular apparatus
Am J Physiol Renal Physiol, July 1, 2003; 285(1): F121 - F129.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Cell Physiol.Home page
S. A. Rajasekaran, J. Hu, J. Gopal, R. Gallemore, S. Ryazantsev, D. Bok, and A. K. Rajasekaran
Na,K-ATPase inhibition alters tight junction structure and permeability in human retinal pigment epithelial cells
Am J Physiol Cell Physiol, June 1, 2003; 284(6): C1497 - C1507.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
J. M. Capasso, C. J. Rivard, L. M. Enomoto, and T. Berl
Chloride, not sodium, stimulates expression of the {gamma} subunit of Na/K-ATPase and activates JNK in response to hypertonicity in mouse IMCD3 cells
PNAS, May 27, 2003; 100(11): 6428 - 6433.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
M. Lindzen, R. Aizman, Y. Lifshitz, I. Lubarski, S. J. D. Karlish, and H. Garty
Structure-Function Relations of Interactions between Na,K-ATPase, the {gamma} Subunit, and Corticosteroid Hormone-induced Factor
J. Biol. Chem., May 23, 2003; 278(21): 18738 - 18743.
[Abstract] [Full Text] [PDF]

Home page
 Ann. N. Y. Acad. Sci.Home page
H. HEBERT, P. PURHONEN, K. THOMSEN, H. VORUM, and A. B. MAUNSBACH
Renal Na,K-ATPase Structure from Cryo-electron Microscopy of Two-Dimensional Crystals
Ann. N.Y. Acad. Sci., April 1, 2003; 986(1): 9 - 16.
[Abstract] [Full Text] [PDF]

Home page
 Ann. N. Y. Acad. Sci.Home page
J. LINGREL, A. MOSELEY, I. DOSTANIC, M. COUGNON, S. HE, P. JAMES, A. WOO, K. O'CONNOR, and J. NEUMANN
Functional Roles of the {alpha} Isoforms of the Na,K-ATPase
Ann. N.Y. Acad. Sci., April 1, 2003; 986(1): 354 - 359.
[Abstract] [Full Text] [PDF]

Home page
 Ann. N. Y. Acad. Sci.Home page
K. J. SWEADNER, E. ARYSTARKHOVA, C. DONNET, and R. K. WETZEL
FXYD Proteins as Regulators of the Na,K-ATPase in the Kidney
Ann. N.Y. Acad. Sci., April 1, 2003; 986(1): 382 - 387.
[Abstract] [Full Text] [PDF]

Home page
 Ann. N. Y. Acad. Sci.Home page
H. GARTY, M. LINDZEN, M. FUZESI, R. AIZMAN, R. GOLDSHLEGER, C. ASHER, and S. J. D. KARLISH
A Specific Functional Interaction between CHIF and Na,K-ATPase: Role of FXYD Proteins in the Cellular Regulation of the Pump
Ann. N.Y. Acad. Sci., April 1, 2003; 986(1): 395 - 400.
[Abstract] [Full Text] [PDF]

Home page
 Ann. N. Y. Acad. Sci.Home page
K. PIHAKASKI-MAUNSBACH, H. VORUM, E.-M. LOCKE, H. GARTY, S. J. D. KARLISH, and A. B. MAUNSBACH
Immunocytochemical Localization of Na,K-ATPase Gamma Subunit and CHIF in Inner Medulla of Rat Kidney
Ann. N.Y. Acad. Sci., April 1, 2003; 986(1): 401 - 409.
[Abstract] [Full Text] [PDF]

Home page
 Ann. N. Y. Acad. Sci.Home page
J. M. CAPASSO, C. J. RIVARD, L. M. ENOMOTO, and T. BERL
Adaptation of Murine Inner Medullary Collecting Duct (IMCD3) Cell Cultures to Hypertonicity
Ann. N.Y. Acad. Sci., April 1, 2003; 986(1): 410 - 415.
[Abstract] [Full Text] [PDF]

Home page
 Ann. N. Y. Acad. Sci.Home page
E. ARYSTARKHOVA and R. K. WETZEL
Gamma Structural Variants Differentially Regulate Na,K-ATPase Properties
Ann. N.Y. Acad. Sci., April 1, 2003; 986(1): 416 - 419.
[Abstract] [Full Text] [PDF]

Home page
 Ann. N. Y. Acad. Sci.Home page
I. C. MEIJ, J. B. KOENDERINK, J. C. DE JONG, J. J. H. H. M. DE PONT, L. A. H. MONNENS, L. P. W. J. VAN DEN HEUVEL, and N. V. A. M. KNOERS
Dominant Isolated Renal Magnesium Loss Is Caused by Misrouting of the Na+,K+-ATPase {gamma}-Subunit
Ann. N.Y. Acad. Sci., April 1, 2003; 986(1): 437 - 443.
[Abstract] [Full Text] [PDF]

Home page
 Ann. N. Y. Acad. Sci.Home page
G. CRAMBERT, P. BEGUIN, M. ULDRY, F. MONNET-TSCHUDI, J.-D. HORISBERGER, H. GARTY, and K. GEERING
FXYD7, the First Brain- and Isoform-Specific Regulator of Na,K-ATPase: Biosynthesis and Function of Its Posttranslational Modifications
Ann. N.Y. Acad. Sci., April 1, 2003; 986(1): 444 - 448.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
M. S. Feschenko, C. Donnet, R. K. Wetzel, N. K. Asinovski, L. R. Jones, and K. J. Sweadner
Phospholemman, a Single-Span Membrane Protein, Is an Accessory Protein of Na,K-ATPase in Cerebellum and Choroid Plexus
J. Neurosci., March 15, 2003; 23(6): 2161 - 2169.
[Abstract] [Full Text] [PDF]

Home page
 Nephrol Dial TransplantHome page
I. C. Meij, L. P. W. J. van den Heuvel, S. Hemmes, W. A. van der Vliet, J. L. Willems, L. A. H. Monnens, and N. V. A. M. Knoers
Exclusion of mutations in FXYD2, CLDN16 and SLC12A3 in two families with primary renal Mg2+ loss
Nephrol. Dial. Transplant., March 1, 2003; 18(3): 512 - 516.
[Abstract] [Full Text] [PDF]

Home page
 Sci SignalHome page
G. Crambert and K. Geering
FXYD Proteins: New Tissue-Specific Regulators of the Ubiquitous Na,K-ATPase
Sci. Signal., January 21, 2003; 2003(166): re1 - re1.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Renal Physiol.Home page
H. Garty, M. Lindzen, R. Scanzano, R. Aizman, M. Fuzesi, R. Goldshleger, N. Farman, R. Blostein, and S. J. D. Karlish
A functional interaction between CHIF and Na-K-ATPase: implication for regulation by FXYD proteins
Am J Physiol Renal Physiol, October 1, 2002; 283(4): F607 - F615.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Renal Physiol.Home page
R. Aizman, C. Asher, M. Fuzesi, H. Latter, P. Lonai, S. J. D. Karlish, and H. Garty
Generation and phenotypic analysis of CHIF knockout mice
Am J Physiol Renal Physiol, September 1, 2002; 283(3): F569 - F577.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
G. Crambert, M. Fuzesi, H. Garty, S. Karlish, and K. Geering
Phospholemman (FXYD1) associates with Na,K-ATPase and regulates its transport properties
PNAS, August 20, 2002; 99(17): 11476 - 11481.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
H. X. Pu, R. Scanzano, and R. Blostein
Distinct Regulatory Effects of the Na,K-ATPase gamma Subunit
J. Biol. Chem., May 31, 2002; 277(23): 20270 - 20276.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Renal Physiol.Home page
J. D. Stockand
New ideas about aldosterone signaling in epithelia
Am J Physiol Renal Physiol, April 1, 2002; 282(4): F559 - F576.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
E. Arystarkhova, C. Donnet, N. K. Asinovski, and K. J. Sweadner
Differential Regulation of Renal Na,K-ATPase by Splice Variants of the gamma Subunit
J. Biol. Chem., March 15, 2002; 277(12): 10162 - 10172.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Cell Physiol.Home page
G. Sweeney, W. Niu, V. A. Canfield, R. Levenson, and A. Klip
Insulin increases plasma membrane content and reduces phosphorylation of Na+-K+ pump alpha 1-subunit in HEK-293 cells
Am J Physiol Cell Physiol, December 1, 2001; 281(6): C1797 - C1803.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
J. M. Capasso, C. Rivard, and T. Berl
The expression of the gamma subunit of Na-K-ATPase is regulated by osmolality via C-terminal Jun kinase and phosphatidylinositol 3-kinase-dependent mechanisms
PNAS, October 25, 2001; (2001) 231309198.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Renal Physiol.Home page
R. K. Wetzel and K. J. Sweadner
Immunocytochemical localization of Na-K-ATPase alpha - and gamma -subunits in rat kidney
Am J Physiol Renal Physiol, September 1, 2001; 281(3): F531 - F545.
[Abstract] [Full Text] [PDF]

Home page
 Physiol. GenomicsHome page
D. H. JONES, M. C. GOLDING, K. J. BARR, G.-H. FONG, and G. M. KIDDER
The mouse Na+-K+-ATPase {gamma}-subunit gene (Fxyd2) encodes three developmentally regulated transcripts
Physiol Genomics, August 28, 2001; 6(3): 129 - 135.
[Abstract] [Full Text] [PDF]

Home page
 IOVSHome page
R. K. Wetzel and K. J. Sweadner
Immunocytochemical Localization of NaK-ATPase Isoforms in the Rat and Mouse Ocular Ciliary Epithelium
Invest. Ophthalmol. Vis. Sci., March 1, 2001; 42(3): 763 - 769.
[Abstract] [Full Text]

Home page
 Physiol. Rev.Home page
E. Feraille and A. Doucet
Sodium-Potassium-Adenosinetriphosphatase-Dependent Sodium Transport in the Kidney: Hormonal Control
Physiol Rev, January 1, 2001; 81(1): 345 - 418.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Cell Physiol.Home page
A. G. Therien and R. Blostein
Mechanisms of sodium pump regulation
Am J Physiol Cell Physiol, September 1, 2000; 279(3): C541 - C566.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
B. Kuster, A. Shainskaya, H. X. Pu, R. Goldshleger, R. Blostein, M. Mann, and S. J. D. Karlish
A New Variant of the gamma Subunit of Renal Na,K-ATPase. IDENTIFICATION BY MASS SPECTROMETRY, ANTIBODY BINDING, AND EXPRESSION IN CULTURED CELLS
J. Biol. Chem., June 9, 2000; 275(24): 18441 - 18446.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
A. L. Woo, P. F. James, and J. B Lingrel
Sperm Motility Is Dependent on a Unique Isoform of the Na,K-ATPase
J. Biol. Chem., June 30, 2000; 275(27): 20693 - 20699.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
Y. A. Mahmmoud, H. Vorum, and F. Cornelius
Identification of a Phospholemman-like Protein from Shark Rectal Glands. EVIDENCE FOR INDIRECT REGULATION OF Na,K-ATPase BY PROTEIN KINASE C VIA A NOVEL MEMBER OF THE FXYDY FAMILY
J. Biol. Chem., November 10, 2000; 275(46): 35969 - 35977.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
C. Donnet, E. Arystarkhova, and K. J. Sweadner
Thermal Denaturation of the Na,K-ATPase Provides Evidence for alpha -alpha Oligomeric Interaction and gamma Subunit Association with the C-terminal Domain
J. Biol. Chem., March 2, 2001; 276(10): 7357 - 7365.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
H. X. Pu, F. Cluzeaud, R. Goldshleger, S. J. D. Karlish, N. Farman, and R. Blostein
Functional Role and Immunocytochemical Localization of the gamma a and gamma b Forms of the Na,K-ATPase gamma Subunit
J. Biol. Chem., June 1, 2001; 276(23): 20370 - 20378.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
J. M. Capasso, C. Rivard, and T. Berl
The expression of the gamma subunit of Na-K-ATPase is regulated by osmolality via C-terminal Jun kinase and phosphatidylinositol 3-kinase-dependent mechanisms
PNAS, November 6, 2001; 98(23): 13414 - 13419.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Renal Physiol.Home page
S. M. Wall, M. P. Fischer, G.-H. Kim, B.-M. Nguyen, and K. A. Hassell
In rat inner medullary collecting duct, NH+4 uptake by the Na,K-ATPase is increased during hypokalemia
Am J Physiol Renal Physiol, January 1, 2002; 282(1): F91 - F102.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Renal Physiol.Home page
E. Arystarkhova, R. K. Wetzel, and K. J. Sweadner
Distribution and oligomeric association of splice forms of Na+-K+-ATPase regulatory gamma -subunit in rat kidney
Am J Physiol Renal Physiol, March 1, 2002; 282(3): F393 - F407.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK