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J Biol Chem, Vol. 275, Issue 19, 14501-14508, May 12, 2000

Acute Regulation of Fatty Acid Uptake Involves the Cellular Redistribution of Fatty Acid Translocase*

Arend BonenDagger §, Joost J. F. P. LuikenDagger ||, Yoga ArumugamDagger , Jan F. C. Glatz, and Narendra N. Tandon**

From the Dagger  Department of Kinesiology, University of Waterloo, Waterloo, Ontario N2L 3G1, Canada, the  Department of Physiology, Maastricht University, 6200 MD Maastricht, The Netherlands, and the ** Thrombosis and Vascular Biology Laboratory, Otsuka America Pharmaceutical, Inc., Rockville, Maryland 20850

We used muscle contraction, which increases fatty acid oxidation, as a model to determine whether fatty acid transport is acutely regulated by fatty acid translocase (FAT/CD36). Palmitate uptake by giant vesicles, obtained from skeletal muscle, was increased by muscle contraction. Kinetic studies indicated that muscle contraction increased Vmax, but Km remained unaltered. Sulfo-N-succinimidyl oleate, a specific inhibitor of FAT/CD36, fully blocked the contraction-induced increase in palmitate uptake. In giant vesicles from contracting muscles, plasma membrane FAT/CD36 was also increased in parallel with the increase in long chain fatty acid uptake. Further studies showed that like GLUT-4, FAT/CD36 is located in both the plasma membrane and intracellularly (endosomally). With muscle contraction, FAT/CD36 at the surface of the muscle was increased, while concomitantly, FAT/CD36 in the intracellular pool was reduced. Similar responses were observed for GLUT-4. We conclude that fatty acid uptake is subject to short term regulation by muscle contraction and involves the translocation of FAT/CD36 from intracellular stores to the sarcolemma, analogous to the regulation of glucose uptake by GLUT-4.

* This work was supported by a grant from the Medical Research Council of Canada.The costs of publication of this article were defrayed in part by the payment of page charges. The article must therefore be hereby marked "advertisement" in accordance with 18 U.S.C. Section 1734 solely to indicate this fact.

§ To whom correspondence should be addressed. Tel.: 1-519-888-1211 (ext. 5214); Fax: 1-519-746-6776; E-mail: abonen@healthy.uwaterloo.ca.

|| Dekker postdoctoral fellow of the Netherlands Heart Foundation.

Copyright © 2000 by The American Society for Biochemistry and Molecular Biology, Inc.
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[Abstract] [Full Text] [PDF]

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Home page
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[Abstract] [Full Text] [PDF]

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[Abstract] [Full Text] [PDF]

Home page
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[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
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[Abstract] [Full Text] [PDF]

Home page
 J. Lipid Res.Home page
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[Abstract] [Full Text] [PDF]

Home page
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Impact on fatty acid metabolism and differential localization of FATP1 and FAT/CD36 proteins delivered in cultured human muscle cells
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[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Endocrinol. Metab.Home page
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[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Endocrinol. Metab.Home page
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[Abstract] [Full Text] [PDF]

Home page
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Home page
 J. Physiol.Home page
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[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
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[Abstract] [Full Text] [PDF]

Home page
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[Abstract] [Full Text] [PDF]

Home page
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M. J. Watt, G. R. Steinberg, G. J. F. Heigenhauser, L. L. Spriet, and D. J. Dyck
Hormone-sensitive lipase activity and triacylglycerol hydrolysis are decreased in rat soleus muscle by cyclopiazonic acid
Am J Physiol Endocrinol Metab, August 1, 2003; 285(2): E412 - E419.
[Abstract] [Full Text] [PDF]

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 DiabetesHome page
J. J.F.P. Luiken, S. L.M. Coort, J. Willems, W. A. Coumans, A. Bonen, G. J. van der Vusse, and J. F.C. Glatz
Contraction-Induced Fatty Acid Translocase/CD36 Translocation in Rat Cardiac Myocytes Is Mediated Through AMP-Activated Protein Kinase Signaling
Diabetes, July 1, 2003; 52(7): 1627 - 1634.
[Abstract] [Full Text] [PDF]

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 Proc. Natl. Acad. Sci. USAHome page
H. Irie, I. B. Krukenkamp, J. F. F. Brinkmann, G. R. Gaudette, A. E. Saltman, W. Jou, J. F. C. Glatz, N. A. Abumrad, and A. Ibrahimi
Myocardial recovery from ischemia is impaired in CD36-null mice and restored by myocyte CD36 expression or medium-chain fatty acids
PNAS, May 27, 2003; 100(11): 6819 - 6824.
[Abstract] [Full Text] [PDF]

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 EndocrinologyHome page
H. H. A. G. M. van der Putten, E. C. H. Friesema, N. A. Abumrad, M. E. Everts, and T. J. Visser
Thyroid Hormone Transport by the Rat Fatty Acid Translocase
Endocrinology, April 1, 2003; 144(4): 1315 - 1323.
[Abstract] [Full Text] [PDF]

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 Am. J. Physiol. Endocrinol. Metab.Home page
J. J. F. P. Luiken, Y. Arumugam, R. C. Bell, J. Calles-Escandon, N. N. Tandon, J. F. C. Glatz, and A. Bonen
Changes in fatty acid transport and transporters are related to the severity of insulin deficiency
Am J Physiol Endocrinol Metab, September 1, 2002; 283(3): E612 - E621.
[Abstract] [Full Text] [PDF]

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 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
M. Z. Tucker and L. P. Turcotte
Brief food restriction increases FA oxidation and glycogen synthesis under insulin-stimulated conditions
Am J Physiol Regulatory Integrative Comp Physiol, April 1, 2002; 282(4): R1210 - R1218.
[Abstract] [Full Text] [PDF]

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 J. Biol. Chem.Home page
G. R. Steinberg, D. J. Dyck, J. Calles-Escandon, N. N. Tandon, J. J. F. P. Luiken, J. F. C. Glatz, and A. Bonen
Chronic Leptin Administration Decreases Fatty Acid Uptake and Fatty Acid Transporters in Rat Skeletal Muscle
J. Biol. Chem., March 8, 2002; 277(11): 8854 - 8860.
[Abstract] [Full Text] [PDF]

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 Am. J. Physiol. Endocrinol. Metab.Home page
J. E. Schaffer
Fatty acid transport: the roads taken
Am J Physiol Endocrinol Metab, February 1, 2002; 282(2): E239 - E246.
[Abstract] [Full Text] [PDF]

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 Am. J. Physiol. Endocrinol. Metab.Home page
J. J. F. P. Luiken, D. J. Dyck, X.-X. Han, N. N. Tandon, Y. Arumugam, J. F. C. Glatz, and A. Bonen
Insulin induces the translocation of the fatty acid transporter FAT/CD36 to the plasma membrane
Am J Physiol Endocrinol Metab, February 1, 2002; 282(2): E491 - E495.
[Abstract] [Full Text] [PDF]

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 Am. J. Physiol. Endocrinol. Metab.Home page
L. P. Turcotte, J. R. Swenberger, and A. J. Yee
High carbohydrate availability increases LCFA uptake and decreases LCFA oxidation in perfused muscle
Am J Physiol Endocrinol Metab, January 1, 2002; 282(1): E177 - E183.
[Abstract] [Full Text] [PDF]

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 Am. J. Physiol. Endocrinol. Metab.Home page
J. J. F. P. Luiken, J. Willems, G. J. van der Vusse, and J. F. C. Glatz
Electrostimulation enhances FAT/CD36-mediated long-chain fatty acid uptake by isolated rat cardiac myocytes
Am J Physiol Endocrinol Metab, October 1, 2001; 281(4): E704 - E712.
[Abstract] [Full Text] [PDF]

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 Am. J. Physiol. Endocrinol. Metab.Home page
S. E. Campbell, D. J. Angus, and M. A. Febbraio
Glucose kinetics and exercise performance during phases of the menstrual cycle: effect of glucose ingestion
Am J Physiol Endocrinol Metab, October 1, 2001; 281(4): E817 - E825.
[Abstract] [Full Text] [PDF]

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 J. Physiol.Home page
L. J C van Loon, P. L Greenhaff, D Constantin-Teodosiu, W. H M Saris, and A. J M Wagenmakers
The effects of increasing exercise intensity on muscle fuel utilisation in humans
J. Physiol., October 1, 2001; 536(1): 295 - 304.
[Abstract] [Full Text] [PDF]

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 Am. J. Physiol. Endocrinol. Metab.Home page
D. J. Dyck, G. Steinberg, and A. Bonen
Insulin increases FA uptake and esterification but reduces lipid utilization in isolated contracting muscle
Am J Physiol Endocrinol Metab, September 1, 2001; 281(3): E600 - E607.
[Abstract] [Full Text] [PDF]

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 J. Biol. Chem.Home page
J. J. F. P. Luiken, Y. Arumugam, D. J. Dyck, R. C. Bell, M. M. L. Pelsers, L. P. Turcotte, N. N. Tandon, J. F. C. Glatz, and A. Bonen
Increased Rates of Fatty Acid Uptake and Plasmalemmal Fatty Acid Transporters in Obese Zucker Rats
J. Biol. Chem., October 26, 2001; 276(44): 40567 - 40573.
[Abstract] [Full Text] [PDF]

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 Am. J. Physiol. Endocrinol. Metab.Home page
G. R. Steinberg, A. Bonen, and D. J. Dyck
Fatty acid oxidation and triacylglycerol hydrolysis are enhanced after chronic leptin treatment in rats
Am J Physiol Endocrinol Metab, March 1, 2002; 282(3): E593 - E600.
[Abstract] [Full Text] [PDF]

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 Am. J. Physiol. Endocrinol. Metab.Home page
M. Tonouchi, H. Hatta, and A. Bonen
Muscle contraction increases lactate transport while reducing sarcolemmal MCT4, but not MCT1
Am J Physiol Endocrinol Metab, May 1, 2002; 282(5): E1062 - E1069.
[Abstract] [Full Text] [PDF]


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