| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
J. Biol. Chem., Vol. 275, Issue 38, 29579-29586, September 22, 2000
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
From Prohibitins, stomatins, and a group of plant
defense response genes are demonstrated to belong to a novel protein
superfamily. This superfamily is bound by similar primary and secondary
predicted protein structures and hydropathy profiles. A
PROSITE-formatted regular expression was generated that is highly
predictive for identifying members of this superfamily using PHI-BLAST.
The superfamily is named PID (proliferation,
ion, and death) because prohibitins are
involved in proliferation and cell cycle control, stomatins are
involved in ion channel regulation, and the plant defense-related genes
are involved in cell death. The plant defense gene family is named HIR
(hypersensitive induced reaction)
because its members are associated with hypersensitive reactions
involving cell death and pathogen resistance. For this study, eight
novel maize genes were introduced: four closely related to prohibitins
(Zm-phb1, Zm-phb2, Zm-phb3,
and Zm-phb4), one to stomatins (Zm-stm1), and three to a gene implicated in plant disease responses
(Zm-hir1, Zm-hir2, and Zm-hir3).
The maize Zm-hir3 gene transcript is up-regulated in a
disease lesion mimic mutation (Les9), supporting a role in maize defense responses. Members of this gene superfamily are involved
in diverse functions, but their structural similarity suggests a
conserved molecular mechanism, which we postulate to be ion channel regulation.
Prohibitins, Stomatins, and Plant Disease Response Genes Compose
a Protein Superfamily That Controls Cell Proliferation, Ion Channel
Regulation, and Death*
,
Hoffmann-La Roche, Vitamins Division, Nutley,
New Jersey 07110 and the § Disease Resistance and
¶ Bioinformatics Departments, Pioneer Hi-Bred International, Inc.,
Johnston, Iowa 50131-0552
*
The costs of publication of this
article were defrayed in part by the
payment of page charges. The article
must therefore be hereby marked
"advertisement" in
accordance with 18 U.S.C. Section
1734 solely to indicate this fact.
To whom correspondence should be addressed: Bioinformatics
Department, Pioneer Hi-Bred International, Inc., 7250 N. W. 62nd Ave.,
Emerson, P. O. Box 552, Johnston, IA 50131-0552. Tel.: 515-270-5949; Fax: 515-334-4729; E-mail: simmonscr@phibred.com.
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
This article has been cited by other articles:
|
|
 |
|
  A. Marmagne, M. Ferro, T. Meinnel, C. Bruley, L. Kuhn, J. Garin, H. Barbier-Brygoo, and G. Ephritikhine A High Content in Lipid-modified Peripheral Proteins and Integral Receptor Kinases Features in the Arabidopsis Plasma Membrane Proteome Mol. Cell. Proteomics, November 1, 2007; 6(11): 1980 - 1996. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 N. Takata, J. Kasuga, D. Takezawa, K. Arakawa, and S. Fujikawa Gene expression associated with increased supercooling capability in xylem parenchyma cells of larch (Larix kaempferi) J. Exp. Bot., October 1, 2007; 58(13): 3731 - 3742. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Morel, S. Claverol, S. Mongrand, F. Furt, J. Fromentin, J.-J. Bessoule, J.-P. Blein, and F. Simon-Plas Proteomics of Plant Detergent-resistant Membranes Mol. Cell. Proteomics, August 1, 2006; 5(8): 1396 - 1411. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Y. Graham The Diphenylether Herbicide Lactofen Induces Cell Death and Expression of Defense-Related Genes in Soybean Plant Physiology, December 1, 2005; 139(4): 1784 - 1794. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T.-J. Wen, F. Hochholdinger, M. Sauer, W. Bruce, and P. S. Schnable The roothairless1 Gene of Maize Encodes a Homolog of sec3, Which Is Involved in Polar Exocytosis Plant Physiology, July 1, 2005; 138(3): 1637 - 1643. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. H.H. Borner, D. J. Sherrier, T. Weimar, L. V. Michaelson, N. D. Hawkins, A. MacAskill, J. A. Napier, M. H. Beale, K. S. Lilley, and P. Dupree Analysis of Detergent-Resistant Membranes in Arabidopsis. Evidence for Plasma Membrane Lipid Rafts Plant Physiology, January 1, 2005; 137(1): 104 - 116. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Marmagne, M.-A. Rouet, M. Ferro, N. Rolland, C. Alcon, J. Joyard, J. Garin, H. Barbier-Brygoo, and G. Ephritikhine Identification of New Intrinsic Proteins in Arabidopsis Plasma Membrane Proteome Mol. Cell. Proteomics, July 1, 2004; 3(7): 675 - 691. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Takahashi, T. Kawasaki, H. L. Wong, U. Suharsono, H. Hirano, and K. Shimamoto Hyperphosphorylation of a Mitochondrial Protein, Prohibitin, Is Induced by Calyculin A in a Rice Lesion-Mimic Mutant cdr1 Plant Physiology, August 1, 2003; 132(4): 1861 - 1869. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Wienkoop and G. Saalbach Proteome Analysis. Novel Proteins Identified at the Peribacteroid Membrane from Lotus japonicus Root Nodules Plant Physiology, March 1, 2003; 131(3): 1080 - 1090. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. Huang, I. Parmryd, F. Nilsson, A. L. Persson, H. B. Pakrasi, B. Andersson, and B. Norling Proteomics of Synechocystis sp. Strain PCC 6803: Identification of Plasma Membrane Proteins Mol. Cell. Proteomics, December 1, 2002; 1(12): 956 - 966. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. Steinmoen, E. Knutsen, and L. S. Havarstein Induction of natural competence in Streptococcus pneumoniae triggers lysis and DNA release from a subfraction of the cell population PNAS, May 28, 2002; 99(11): 7681 - 7686. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| All ASBMB Journals | Molecular and Cellular Proteomics |
| Journal of Lipid Research | ASBMB Today |
