JBC

HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Originally published In Press as doi:10.1074/jbc.M003430200 on August 18, 2000

J. Biol. Chem., Vol. 275, Issue 47, 36999-37005, November 24, 2000
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
275/47/36999    most recent
M003430200v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Kim, S. H.
Right arrow Articles by Sacks, D. B.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Kim, S. H.
Right arrow Articles by Sacks, D. B.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?

E-cadherin-mediated Cell-Cell Attachment Activates Cdc42*

Stella H. Kim, Zhigang Li, and David B. SacksDagger

From the Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115

E-cadherin is a transmembrane protein that mediates Ca2+-dependent cell-cell adhesion. Cdc42, a member of the Rho family of small GTPases, participates in cytoskeletal rearrangement and cell cycle progression. Recent evidence reveals that members of the Rho family modulate E-cadherin function. To further examine the role of Cdc42 in E-cadherin-mediated cell-cell adhesion, we developed an assay for active Cdc42 using the GTPase-binding domain of the Wiskott-Aldrich syndrome protein. Initiation of E-cadherin-mediated cell-cell attachment significantly increased in a time-dependent manner the amount of active Cdc42 in MCF-7 epithelial cell lysates. By contrast, Cdc42 activity was not increased under identical conditions in MCF-7 cells incubated with anti-E-cadherin antibodies nor in MDA-MB-231 (E-cadherin negative) epithelial cells. By fusing the Wiskott-Aldrich syndrome protein/GTPase-binding domain to a green fluorescent protein, activation of endogenous Cdc42 by E-cadherin was demonstrated in live cells. These data indicate that E-cadherin activates Cdc42, demonstrating bi-directional interactions between the Rho- and E-cadherin signaling pathways.

* This work was supported in part by National Institutes of Health Grant CA75205.The costs of publication of this article were defrayed in part by the payment of page charges. The article must therefore be hereby marked "advertisement" in accordance with 18 U.S.C. Section 1734 solely to indicate this fact.

Dagger To whom correspondence should be addressed: Brigham and Women's Hospital, Thorn 530, 75 Francis St., Boston, MA 02115. Tel.: 617-732-6627; Fax: 617-278-6921; E-mail: dsacks@rics.bwh.harvard.edu.

Copyright © 2000 by The American Society for Biochemistry and Molecular Biology, Inc.
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?


This article has been cited by other articles:


Home page
 J. Cell Sci.Home page
M. J. Wheelock, Y. Shintani, M. Maeda, Y. Fukumoto, and K. R. Johnson
Cadherin switching
J. Cell Sci., March 15, 2008; 121(6): 727 - 735.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
Y. Shen, D. S. Hirsch, C. A. Sasiela, and W. J. Wu
Cdc42 Regulates E-cadherin Ubiquitination and Degradation through an Epidermal Growth Factor Receptor to Src-mediated Pathway
J. Biol. Chem., February 22, 2008; 283(8): 5127 - 5137.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
L. Jadeski, J. M. Mataraza, H.-W. Jeong, Z. Li, and D. B. Sacks
IQGAP1 Stimulates Proliferation and Enhances Tumorigenesis of Human Breast Epithelial Cells
J. Biol. Chem., January 11, 2008; 283(2): 1008 - 1017.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
M. D. Brown, L. Bry, Z. Li, and D. B. Sacks
IQGAP1 Regulates Salmonella Invasion through Interactions with Actin, Rac1, and Cdc42
J. Biol. Chem., October 12, 2007; 282(41): 30265 - 30272.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. Biol.Home page
N. P. Jones and M. Katan
Role of Phospholipase C{gamma}1 in Cell Spreading Requires Association with a {beta}-Pix/GIT1-Containing Complex, Leading to Activation of Cdc42 and Rac1
Mol. Cell. Biol., August 15, 2007; 27(16): 5790 - 5805.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
Q. Tao, S. Nandadasa, P. D. McCrea, J. Heasman, and C. Wylie
G-protein-coupled signals control cortical actin assembly by controlling cadherin expression in the early Xenopus embryo
Development, July 15, 2007; 134(14): 2651 - 2661.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
H.-W. Jeong, Z. Li, M. D. Brown, and D. B. Sacks
IQGAP1 Binds Rap1 and Modulates Its Activity
J. Biol. Chem., July 13, 2007; 282(28): 20752 - 20762.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Cell Physiol.Home page
A. Kraemer, M. Goodwin, S. Verma, A. S. Yap, and R. G. Ali
Rac is a dominant regulator of cadherin-directed actin assembly that is activated by adhesive ligation independently of Tiam1
Am J Physiol Cell Physiol, March 1, 2007; 292(3): C1061 - C1069.
[Abstract] [Full Text] [PDF]

Home page
 J. Cell Sci.Home page
S. Babb-Clendenon, Y.-c. Shen, Q. Liu, K. E. Turner, M. S. Mills, G. W. Cook, C. A. Miller, V. H. Gattone II, K. F. Barald, and J. A. Marrs
Cadherin-2 participates in the morphogenesis of the zebrafish inner ear
J. Cell Sci., December 15, 2006; 119(24): 5169 - 5177.
[Abstract] [Full Text] [PDF]

Home page
 J. Cell Biol.Home page
T. Otani, T. Ichii, S. Aono, and M. Takeichi
Cdc42 GEF Tuba regulates the junctional configuration of simple epithelial cells
J. Cell Biol., October 9, 2006; 175(1): 135 - 146.
[Abstract] [Full Text] [PDF]

Home page
 J. Cell Biol.Home page
A. Seth, C. Otomo, and M. K. Rosen
Autoinhibition regulates cellular localization and actin assembly activity of the diaphanous-related formins FRL{alpha} and mDia1
J. Cell Biol., August 28, 2006; 174(5): 701 - 713.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Biol. CellHome page
A. Robert, N. Smadja-Lamere, M.-C. Landry, C. Champagne, R. Petrie, N. Lamarche-Vane, H. Hosoya, and J. N. Lavoie
Adenovirus E4orf4 Hijacks Rho GTPase-dependent Actin Dynamics to Kill Cells: A Role for Endosome-associated Actin Assembly
Mol. Biol. Cell, July 1, 2006; 17(7): 3329 - 3344.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
J. L. Sallee, E. S. Wittchen, and K. Burridge
Regulation of Cell Adhesion by Protein-tyrosine Phosphatases: II. CELL-CELL ADHESION
J. Biol. Chem., June 16, 2006; 281(24): 16189 - 16192.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
L. Li, Z. Li, P. M. Howley, and D. B. Sacks
E6AP and Calmodulin Reciprocally Regulate Estrogen Receptor Stability
J. Biol. Chem., January 27, 2006; 281(4): 1978 - 1985.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
J.-G. Ren, Z. Li, D. L. Crimmins, and D. B. Sacks
Self-association of IQGAP1: CHARACTERIZATION AND FUNCTIONAL SEQUELAE
J. Biol. Chem., October 14, 2005; 280(41): 34548 - 34557.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Biol. CellHome page
A. I. Ivanov, D. Hunt, M. Utech, A. Nusrat, and C. A. Parkos
Differential Roles for Actin Polymerization and a Myosin II Motor in Assembly of the Epithelial Apical Junctional Complex
Mol. Biol. Cell, June 1, 2005; 16(6): 2636 - 2650.
[Abstract] [Full Text] [PDF]

Home page
 J. Cell Biol.Home page
H. A. Benink and W. M. Bement
Concentric zones of active RhoA and Cdc42 around single cell wounds
J. Cell Biol., January 31, 2005; 168(3): 429 - 439.
[Abstract] [Full Text] [PDF]

Home page
 J. Cell Biol.Home page
Y.-S. Chu, W. A. Thomas, O. Eder, F. Pincet, E. Perez, J. P. Thiery, and S. Dufour
Force measurements in E-cadherin-mediated cell doublets reveal rapid adhesion strengthened by actin cytoskeleton remodeling through Rac and Cdc42
J. Cell Biol., December 20, 2004; 167(6): 1183 - 1194.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
K. Grohmanova, D. Schlaepfer, D. Hess, P. Gutierrez, M. Beck, and R. Kroschewski
Phosphorylation of IQGAP1 Modulates Its Binding to Cdc42, Revealing a New Type of Rho-GTPase Regulator
J. Biol. Chem., November 19, 2004; 279(47): 48495 - 48504.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. Biol.Home page
X.-F. Liu, H. Ishida, R. Raziuddin, and T. Miki
Nucleotide Exchange Factor ECT2 Interacts with the Polarity Protein Complex Par6/Par3/Protein Kinase C{zeta} (PKC{zeta}) and Regulates PKC{zeta} Activity
Mol. Cell. Biol., August 1, 2004; 24(15): 6665 - 6675.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. Biol.Home page
C. Hogan, N. Serpente, P. Cogram, C. R. Hosking, C. U. Bialucha, S. M. Feller, V. M. M. Braga, W. Birchmeier, and Y. Fujita
Rap1 Regulates the Formation of E-Cadherin-Based Cell-Cell Contacts
Mol. Cell. Biol., August 1, 2004; 24(15): 6690 - 6700.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
E. Johnson, C. S. Theisen, K. R. Johnson, and M. J. Wheelock
R-cadherin Influences Cell Motility via Rho Family GTPases
J. Biol. Chem., July 23, 2004; 279(30): 31041 - 31049.
[Abstract] [Full Text] [PDF]

Home page
 BloodHome page
Y. Calle, G. E. Jones, C. Jagger, K. Fuller, M. P. Blundell, J. Chow, T. Chambers, and A. J. Thrasher
WASp deficiency in mice results in failure to form osteoclast sealing zones and defects in bone resorption
Blood, May 1, 2004; 103(9): 3552 - 3561.
[Abstract] [Full Text] [PDF]

Home page
 J. Cell Biol.Home page
X. Fang, H. Ji, S.-W. Kim, J.-I. Park, T. G. Vaught, P. Z. Anastasiadis, M. Ciesiolka, and P. D. McCrea
Vertebrate development requires ARVCF and p120 catenins and their interplay with RhoA and Rac
J. Cell Biol., April 12, 2004; 165(1): 87 - 98.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Biol. CellHome page
S. W. Straight, K. Shin, V. C. Fogg, S. Fan, C.-J. Liu, M. Roh, and B. Margolis
Loss of PALS1 Expression Leads to Tight Junction and Polarity Defects
Mol. Biol. Cell, April 1, 2004; 15(4): 1981 - 1990.
[Abstract] [Full Text] [PDF]

Home page
 J. Cell Sci.Home page
O. Pertz and K. M. Hahn
Designing biosensors for Rho family proteins -- deciphering the dynamics of Rho family GTPase activation in living cells
J. Cell Sci., March 15, 2004; 117(8): 1313 - 1318.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Biol. CellHome page
J. Noritake, M. Fukata, K. Sato, M. Nakagawa, T. Watanabe, N. Izumi, S. Wang, Y. Fukata, and K. Kaibuchi
Positive Role of IQGAP1, an Effector of Rac1, in Actin-Meshwork Formation at Sites of Cell-Cell Contact
Mol. Biol. Cell, March 1, 2004; 15(3): 1065 - 1076.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Biol. CellHome page
T. Hoshino, K. Shimizu, T. Honda, T. Kawakatsu, T. Fukuyama, T. Nakamura, M. Matsuda, and Y. Takai
A Novel Role of Nectins in Inhibition of the E-Cadherin-induced Activation of Rac and Formation of Cell-Cell Adherens Junctions
Mol. Biol. Cell, March 1, 2004; 15(3): 1077 - 1088.
[Abstract] [Full Text] [PDF]

Home page
 Circ. Res.Home page
P. Kouklis, M. Konstantoulaki, S. Vogel, M. Broman, and A. B. Malik
Cdc42 Regulates the Restoration of Endothelial Barrier Function
Circ. Res., February 6, 2004; 94(2): 159 - 166.
[Abstract] [Full Text] [PDF]

Home page
 J. Cell Sci.Home page
K. Ebnet, A. Suzuki, S. Ohno, and D. Vestweber
Junctional adhesion molecules (JAMs): more molecules with dual functions?
J. Cell Sci., January 1, 2004; 117(1): 19 - 29.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
H.-B. Guo, I. Lee, M. Kamar, and M. Pierce
N-Acetylglucosaminyltransferase V Expression Levels Regulate Cadherin-associated Homotypic Cell-Cell Adhesion and Intracellular Signaling Pathways
J. Biol. Chem., December 26, 2003; 278(52): 52412 - 52424.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
J. M. Mataraza, M. W. Briggs, Z. Li, A. Entwistle, A. J. Ridley, and D. B. Sacks
IQGAP1 Promotes Cell Motility and Invasion
J. Biol. Chem., October 17, 2003; 278(42): 41237 - 41245.
[Abstract] [Full Text] [PDF]

Home page
 J. Cell Biol.Home page
M. Shigeta, N. Sanzen, M. Ozawa, J. Gu, H. Hasegawa, and K. Sekiguchi
CD151 regulates epithelial cell-cell adhesion through PKC- and Cdc42-dependent actin cytoskeletal reorganization
J. Cell Biol., October 13, 2003; 163(1): 165 - 176.
[Abstract] [Full Text] [PDF]

Home page
 J. Cell Sci.Home page
K. Ebnet, M. Aurrand-Lions, A. Kuhn, F. Kiefer, S. Butz, K. Zander, M.-K. M. z. Brickwedde, A. Suzuki, B. A. Imhof, and D. Vestweber
The junctional adhesion molecule (JAM) family members JAM-2 and JAM-3 associate with the cell polarity protein PAR-3: a possible role for JAMs in endothelial cell polarity
J. Cell Sci., October 1, 2003; 116(19): 3879 - 3891.
[Abstract] [Full Text] [PDF]

Home page
 J. Cell Sci.Home page
K. A. DeMali and K. Burridge
Coupling membrane protrusion and cell adhesion
J. Cell Sci., June 15, 2003; 116(12): 2389 - 2397.
[Abstract] [Full Text] [PDF]

Home page
 ScienceHome page
C. Nizak, S. Monier, E. del Nery, S. Moutel, B. Goud, and F. Perez
Recombinant Antibodies to the Small GTPase Rab6 as Conformation Sensors
Science, May 9, 2003; 300(5621): 984 - 987.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
P. Kouklis, M. Konstantoulaki, and A. B. Malik
VE-cadherin-induced Cdc42 Signaling Regulates Formation of Membrane Protrusions in Endothelial Cells
J. Biol. Chem., April 25, 2003; 278(18): 16230 - 16236.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
N. K. Noren, W. T. Arthur, and K. Burridge
Cadherin Engagement Inhibits RhoA via p190RhoGAP
J. Biol. Chem., April 11, 2003; 278(16): 13615 - 13618.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
D. Schneeberger and T. Raabe
Mbt, a Drosophila PAK protein, combines with Cdc42 to regulate photoreceptor cell morphogenesis
Development, February 1, 2003; 130(3): 427 - 437.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
L. Li, Z. Li, and D. B. Sacks
Calmodulin Regulates the Transcriptional Activity of Estrogen Receptors. SELECTIVE INHIBITION OF CALMODULIN FUNCTION IN SUBCELLULAR COMPARTMENTS
J. Biol. Chem., January 3, 2003; 278(2): 1195 - 1200.
[Abstract] [Full Text] [PDF]

Home page
 J. Cell Biol.Home page
A. S. Yap and E. M. Kovacs
Direct cadherin-activated cell signaling: a view from the plasma membrane
J. Cell Biol., January 2, 2003; 160(1): 11 - 16.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
T. Kawakatsu, K. Shimizu, T. Honda, T. Fukuhara, T. Hoshino, and Y. Takai
trans-Interactions of Nectins Induce Formation of Filopodia and Lamellipodia through the Respective Activation of Cdc42 and Rac Small G Proteins
J. Biol. Chem., December 20, 2002; 277(52): 50749 - 50755.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
M. D. H. Hansen, J. S. Ehrlich, and W. J. Nelson
Molecular Mechanism for Orienting Membrane and Actin Dynamics to Nascent Cell-Cell Contacts in Epithelial Cells
J. Biol. Chem., November 15, 2002; 277(47): 45371 - 45376.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
H. G. Munshi, S. Ghosh, S. Mukhopadhyay, Y. I. Wu, R. Sen, K. J. Green, and M. S. Stack
Proteinase Suppression by E-cadherin-mediated Cell-Cell Attachment in Premalignant Oral Keratinocytes
J. Biol. Chem., October 4, 2002; 277(41): 38159 - 38167.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
M. Betson, E. Lozano, J. Zhang, and V. M. M. Braga
Rac Activation upon Cell-Cell Contact Formation Is Dependent on Signaling from the Epidermal Growth Factor Receptor
J. Biol. Chem., September 27, 2002; 277(40): 36962 - 36969.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
N. L. Tran, D. G. Adams, R. R. Vaillancourt, and R. L. Heimark
Signal Transduction from N-cadherin Increases Bcl-2. REGULATION OF THE PHOSPHATIDYLINOSITOL 3-KINASE/Akt PATHWAY BY HOMOPHILIC ADHESION AND ACTIN CYTOSKELETAL ORGANIZATION
J. Biol. Chem., August 30, 2002; 277(36): 32905 - 32914.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
J.-T. Kim and C.-K. Joo
Involvement of Cell-Cell Interactions in the Rapid Stimulation of Cas Tyrosine Phosphorylation and Src Kinase Activity by Transforming Growth Factor-beta 1
J. Biol. Chem., August 23, 2002; 277(35): 31938 - 31948.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
J. M. Swart-Mataraza, Z. Li, and D. B. Sacks
IQGAP1 Is a Component of Cdc42 Signaling to the Cytoskeleton
J. Biol. Chem., June 28, 2002; 277(27): 24753 - 24763.
[Abstract] [Full Text] [PDF]

Home page
 Genes Dev.Home page
L. Van Aelst and M. Symons
Role of Rho family GTPases in epithelial morphogenesis
Genes & Dev., May 1, 2002; 16(9): 1032 - 1054.
[Full Text] [PDF]

Home page
 Mol. Biol. CellHome page
M. G. Lampugnani, A. Zanetti, F. Breviario, G. Balconi, F. Orsenigo, M. Corada, R. Spagnuolo, M. Betson, V. Braga, and E. Dejana
VE-Cadherin Regulates Endothelial Actin Activating Rac and Increasing Membrane Association of Tiam
Mol. Biol. Cell, April 1, 2002; 13(4): 1175 - 1189.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
P. Laprise, P. Chailler, M. Houde, J.-F. Beaulieu, M.-J. Boucher, and N. Rivard
Phosphatidylinositol 3-Kinase Controls Human Intestinal Epithelial Cell Differentiation by Promoting Adherens Junction Assembly and p38 MAPK Activation
J. Biol. Chem., March 1, 2002; 277(10): 8226 - 8234.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
M. W. Briggs, Z. Li, and D. B. Sacks
IQGAP1-mediated Stimulation of Transcriptional Co-activation by beta -Catenin Is Modulated by Calmodulin
J. Biol. Chem., February 22, 2002; 277(9): 7453 - 7465.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
S. Y. Sokol, Z. Li, and D. B. Sacks
The Effect of IQGAP1 on Xenopus Embryonic Ectoderm Requires Cdc42
J. Biol. Chem., December 14, 2001; 276(51): 48425 - 48430.
[Abstract] [Full Text] [PDF]

Home page
 J. Cell Sci.Home page
M Nakagawa, M Fukata, M Yamaga, N Itoh, and K Kaibuchi
Recruitment and activation of Rac1 by the formation of E-cadherin-mediated cell-cell adhesion sites
J. Cell Sci., January 5, 2001; 114(10): 1829 - 1838.
[Abstract] [PDF]

Home page
 J. Biol. Chem.Home page
N. K. Noren, C. M. Niessen, B. M. Gumbiner, and K. Burridge
Cadherin Engagement Regulates Rho family GTPases
J. Biol. Chem., August 31, 2001; 276(36): 33305 - 33308.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
E. M. Kovacs, R. G. Ali, A. J. McCormack, and A. S. Yap
E-cadherin Homophilic Ligation Directly Signals through Rac and Phosphatidylinositol 3-Kinase to Regulate Adhesive Contacts
J. Biol. Chem., February 15, 2002; 277(8): 6708 - 6718.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Biol. CellHome page
S. Mary, S. Charrasse, M. Meriane, F. Comunale, P. Travo, A. Blangy, and C. Gauthier-Rouviere
Biogenesis of N-Cadherin-dependent Cell-Cell Contacts in Living Fibroblasts Is a Microtubule-dependent Kinesin-driven Mechanism
Mol. Biol. Cell, January 1, 2002; 13(1): 285 - 301.
[Abstract] [Full Text] [PDF]


HOME