| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
J. Biol. Chem., Vol. 276, Issue 8, 5584-5590, February 23, 2001
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
From the Laboratoire de Biochimie et Physiologie Moléculaire
des Plantes, CNRS UMR 5004, Agro-M/INRA, 34060 Montpellier Cedex 1, France
In eukaryotic cells, ferritin synthesis is
controlled by the intracellular iron status. In mammalian cells, iron
derepresses ferritin mRNA translation, whereas it induces ferritin
gene transcription in plants. Promoter deletion and site-directed
mutagenesis analysis, combined with gel shift assays, has allowed
identification of a new cis-regulatory element in the
promoter region of the ZmFer1 maize ferritin gene. This
Iron-Dependent Regulatory Sequence (IDRS) is responsible for
transcriptional repression of ZmFer1 under low iron supply
conditions. The IDRS is specific to the ZmFer1 iron-dependent regulation and does not mediate the
antioxidant response that we have previously reported (Savino et
al. (1997) J. Biol. Chem. 272, 33319-33326). In
addition, we have cloned AtFer1, the Arabidopsis
thaliana ZmFer1 orthologue. The IDRS element is conserved in the
AtFer1 promoter region and is functional as shown by
transient assay in A. thaliana cells and stable
transformation in A. thaliana transgenic plants,
demonstrating its ubiquity in the plant kingdom.
The nucleotide sequence(s) reported in this paper has been submitted to the GenBankTM/EMBL Data Bank with accession number(s) AF229850.
Characterization of an Iron-dependent Regulatory
Sequence Involved in the Transcriptional Control of AtFer1
and ZmFer1 Plant Ferritin Genes by Iron*
,
*
This work was supported by the CNRS (Program Biologie
Cellulaire: du Normal au Pathologique Grant 96003).The costs of publication of this
article were defrayed in part by the
payment of page charges. The article
must therefore be hereby marked
"advertisement" in accordance with 18 U.S.C. Section
1734 solely to indicate this fact.
Present address: Génétique Moléculaire des
Plantes, Université de Picardie Jules Verne, 80039 Amiens
Cédex, France.
§
To whom correspondence should be addressed: Tel.: 33-4-9961-2323;
Fax: 33-4-6752-5737; E-mail: lobreaux@ensam.inra.fr.
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
This article has been cited by other articles:
|
|
 |
|
  J. C. Long, F. Sommer, M. D. Allen, S.-F. Lu, and S. S. Merchant FER1 and FER2 Encoding Two Ferritin Complexes in Chlamydomonas reinhardtii Chloroplasts Are Regulated by Iron Genetics, May 1, 2008; 179(1): 137 - 147. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. J. Romney, C. Thacker, and E. A. Leibold An Iron Enhancer Element in the FTN-1 Gene Directs Iron-dependent Expression in Caenorhabditis elegans Intestine J. Biol. Chem., January 11, 2008; 283(2): 716 - 725. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 X. Fei and X. Deng A Novel Fe Deficiency-Responsive Element (FeRE) Regulates the Expression of atx1 in Chlamydomonas reinharditii Plant Cell Physiol., October 1, 2007; 48(10): 1496 - 1503. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. M. Strozycki, A. Szczurek, B. Lotocka, M. Figlerowicz, and A. B. Legocki Ferritins and nodulation in Lupinus luteus: iron management in indeterminate type nodules J. Exp. Bot., September 22, 2007; (2007) erm152v1. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. Liu, D. L. Greenshields, R. Sammynaiken, R. N. Hirji, G. Selvaraj, and Y. Wei Targeted alterations in iron homeostasis underlie plant defense responses J. Cell Sci., February 15, 2007; 120(4): 596 - 605. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. Arnaud, I. Murgia, J. Boucherez, J.-F. Briat, F. Cellier, and F. Gaymard An Iron-induced Nitric Oxide Burst Precedes Ubiquitin-dependent Protein Degradation for Arabidopsis AtFer1 Ferritin Gene Expression J. Biol. Chem., August 18, 2006; 281(33): 23579 - 23588. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Kobayashi, M. Suzuki, H. Inoue, R. N. Itai, M. Takahashi, H. Nakanishi, S. Mori, and N. K. Nishizawa Expression of iron-acquisition-related genes in iron-deficient rice is co-ordinately induced by partially conserved iron-deficiency-responsive elements J. Exp. Bot., May 1, 2005; 56(415): 1305 - 1316. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. P. Colangelo and M. L. Guerinot The Essential Basic Helix-Loop-Helix Protein FIT1 Is Required for the Iron Deficiency Response PLANT CELL, December 1, 2004; 16(12): 3400 - 3412. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. C. Rutherford and A. J. Bird Metal-Responsive Transcription Factors That Regulate Iron, Zinc, and Copper Homeostasis in Eukaryotic Cells Eukaryot. Cell, February 1, 2004; 3(1): 1 - 13. [Full Text] [PDF]
|
|
|
|
 |
|
 P. Fourcroy, G. Vansuyt, S. Kushnir, D. Inze, and J.-F. Briat Iron-Regulated Expression of a Cytosolic Ascorbate Peroxidase Encoded by the APX1 Gene in Arabidopsis Seedlings Plant Physiology, February 1, 2004; 134(2): 605 - 613. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Guo and S. P. Moose Conserved Noncoding Sequences among Cultivated Cereal Genomes Identify Candidate Regulatory Sequence Elements and Patterns of Promoter Evolution PLANT CELL, May 1, 2003; 15(5): 1143 - 1158. [Abstract] [Full Text]
|
|
|
|
|
|
B. L. Gourley, S. B. Parker, B. J. Jones, K. B. Zumbrennen, and E. A. Leibold Cytosolic Aconitase and Ferritin Are Regulated by Iron in Caenorhabditis elegans J. Biol. Chem., January 24, 2003; 278(5): 3227 - 3234. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 F. M. Torti and S. V. Torti Regulation of ferritin genes and protein Blood, May 15, 2002; 99(10): 3505 - 3516. [Full Text] [PDF]
|
|
|
|
|
|
C.-D. Tsai, H.-W. Liu, and J.-H. Tai Characterization of an Iron-responsive Promoter in the Protozoan Pathogen Trichomonas vaginalis J. Biol. Chem., February 8, 2002; 277(7): 5153 - 5162. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| All ASBMB Journals | Molecular and Cellular Proteomics |
| Journal of Lipid Research | ASBMB Today |
