HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

J. Biol. Chem., Vol. 279, Issue 8, 6986-6993, February 20, 2004

This Article Full Text Full Text (PDF) All Versions of this Article: 279/8/6986    most recent M310060200v1 Submit a Letter to Editor Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Yoshida, Y. Articles by Hasunuma, K. Search for Related Content PubMed PubMed Citation Articles by Yoshida, Y. Articles by Hasunuma, K. Social Bookmarking                      What's this?

Reactive Oxygen Species Affect Photomorphogenesis in Neurospora crassa^*

Yusuke Yoshida and Kohji Hasunuma

From the Kihara Institute for Biological Research, Graduate School of Integrated Science, Yokohama City University, 641-12 Maioka-cho, Totsuka-ku, Yokohama 244-0813, Japan

In Neurospora crassa, several biological phenomena such as the synthesis of carotenoids in the mycelia and polarity of perithecia are regulated by light. We found that a sod-1 mutant, with a defective Cu,Zn-type superoxide dismutase (SOD), showed accelerated light-dependent induction of carotenoid accumulation in the mycelia compared with the wild type. The initial rate of light-induced carotenoid accumulation in the sod-1 mutant was faster than that in the vvd mutant known to accumulate high concentrations. This acceleration was suppressed by treatment with antioxidant reagents. Light-induced transcription of genes involved in carotenoid synthesis, al-1, -2, and -3, was sustained in the sod-1 mutant, whereas it was transient in the wild type. Moreover sod-1 was defective in terms of light-induced polarity of perithecia. By genetic analysis, the enhancement in light-inducible carotenoid synthesis in sod-1 was dependent on the wild type alleles of wc-1 and wc-2. However, the sod-1;vvd double mutant showed additive effects on the carotenoid accumulation in the mycelia. These results suggested that intracellular reactive oxygen species regulated by SOD-1 could affect the light-signal transduction pathway via WC proteins.

Received for publication, September 10, 2003 , and in revised form, November 5, 2003.

^* This work is supported by a grant-in-aid from Japan-Korea Co-operative Work from the Japan Society for the Promotion of Science, the Kihara Memorial Yokohama Foundation for the Advancement of Life Science, and the Mishima Kaiun Memorial Foundation. The costs of publication of this article were defrayed in part by the payment of page charges. This article must therefore be hereby marked "advertisement" in accordance with 18 U.S.C. Section 1734 solely to indicate this fact.

To whom correspondence should be addressed. Tel.: 81-45-820-1903; Fax: 81-45-820-1901; E-mail: kohji{at}yokohama-cu.ac.jp.

CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

This article has been cited by other articles:

				F. Wen, D. Xing, and L. Zhang Hydrogen peroxide is involved in high blue light-induced chloroplast avoidance movements in Arabidopsis J. Exp. Bot., July 1, 2008; 59(10): 2891 - 2901. [Abstract] [Full Text] [PDF]

				M. A. Friedl, M. Schmoll, C. P. Kubicek, and I. S. Druzhinina Photostimulation of Hypocrea atroviridis growth occurs due to a cross-talk of carbon metabolism, blue light receptors and response to oxidative stress Microbiology, April 1, 2008; 154(4): 1229 - 1241. [Abstract] [Full Text] [PDF]

				M. J. Egan, Z.-Y. Wang, M. A. Jones, N. Smirnoff, and N. J. Talbot Generation of reactive oxygen species by fungal NADPH oxidases is required for rice blast disease PNAS, July 10, 2007; 104(28): 11772 - 11777. [Abstract] [Full Text] [PDF]

				W. J. Belden, L. F. Larrondo, A. C. Froehlich, M. Shi, C.-H. Chen, J. J. Loros, and J. C. Dunlap The band mutation in Neurospora crassa is a dominant allele of ras-1 implicating RAS signaling in circadian output Genes & Dev., June 15, 2007; 21(12): 1494 - 1505. [Abstract] [Full Text] [PDF]

				B. D. Zoltowski, C. Schwerdtfeger, J. Widom, J. J. Loros, A. M. Bilwes, J. C. Dunlap, and B. R. Crane Conformational Switching in the Fungal Light Sensor Vivid Science, May 18, 2007; 316(5827): 1054 - 1057. [Abstract] [Full Text] [PDF]

				J. J. Loros, J. C. Dunlap, L. F. Larrondo, M. Shi, W. J. Belden, V. D. Gooch, C.-H. Chen, C. L. Baker, A. Mehra, H. V. Colot, et al. Circadian Output, Input, and Intracellular Oscillators: Insights into the Circadian Systems of Single Cells Cold Spring Harb Symp Quant Biol, January 1, 2007; 72(0): 201 - 214. [Abstract] [PDF]

				L. Lanfranco, M. Novero, and P. Bonfante The Mycorrhizal Fungus Gigaspora margarita Possesses a CuZn Superoxide Dismutase That Is Up-Regulated during Symbiosis with Legume Hosts Plant Physiology, April 1, 2005; 137(4): 1319 - 1330. [Abstract] [Full Text] [PDF]