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J. Biol. Chem., Vol. 281, Issue 3, 1612-1619, January 20, 2006
Soluble Interleukin-15 Receptor
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K. Khawam, J. Giron-Michel, Y. Gu, A. Perier, M. Giuliani, A. Caignard, A. Devocelle, S. Ferrini, M. Fabbi, B. Charpentier, et al. Human Renal Cancer Cells Express a Novel Membrane-Bound Interleukin-15 that Induces, in Response to the Soluble Interleukin-15 Receptor {alpha} Chain, Epithelial-to-Mesenchymal Transition Cancer Res., February 15, 2009; 69(4): 1561 - 1569. [Abstract] [Full Text] [PDF] |
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N. D. Huntington, N. Legrand, N. L. Alves, B. Jaron, K. Weijer, A. Plet, E. Corcuff, E. Mortier, Y. Jacques, H. Spits, et al. IL-15 trans-presentation promotes human NK cell development and differentiation in vivo J. Exp. Med., January 16, 2009; 206(1): 25 - 34. [Abstract] [Full Text] [PDF] |
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J. Rowley, A. Monie, C.-F. Hung, and T.-C. Wu Inhibition of Tumor Growth by NK1.1+ Cells and CD8+ T Cells Activated by IL-15 through Receptor {beta}/Common {gamma} Signaling in trans J. Immunol., December 15, 2008; 181(12): 8237 - 8247. [Abstract] [Full Text] [PDF] |
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T. Y. Wuest, J. Willette-Brown, S. K. Durum, and A. A. Hurwitz The influence of IL-2 family cytokines on activation and function of naturally occurring regulatory T cells J. Leukoc. Biol., October 1, 2008; 84(4): 973 - 980. [Abstract] [Full Text] [PDF] |
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C. Badoual, G. Bouchaud, N. E. H. Agueznay, E. Mortier, S. Hans, A. Gey, F. Fernani, S. Peyrard, P. L. -Puig, P. Bruneval, et al. The Soluble {alpha} Chain of Interleukin-15 Receptor: A Proinflammatory Molecule Associated with Tumor Progression in Head and Neck Cancer Cancer Res., May 15, 2008; 68(10): 3907 - 3914. [Abstract] [Full Text] [PDF] |
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E. Mortier, T. Woo, R. Advincula, S. Gozalo, and A. Ma IL-15R{alpha} chaperones IL-15 to stable dendritic cell membrane complexes that activate NK cells via trans presentation J. Exp. Med., May 12, 2008; 205(5): 1213 - 1225. [Abstract] [Full Text] [PDF] |
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A. I. Kokaji, D. L. Hockley, and K. P. Kane IL-15 Transpresentation Augments CD8+ T Cell Activation and Is Required for Optimal Recall Responses by Central Memory CD8+ T Cells J. Immunol., April 1, 2008; 180(7): 4391 - 4401. [Abstract] [Full Text] [PDF] |
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C. Bergamaschi, M. Rosati, R. Jalah, A. Valentin, V. Kulkarni, C. Alicea, G.-M. Zhang, V. Patel, B. K. Felber, and G. N. Pavlakis Intracellular Interaction of Interleukin-15 with Its Receptor {alpha} during Production Leads to Mutual Stabilization and Increased Bioactivity J. Biol. Chem., February 15, 2008; 283(7): 4189 - 4199. [Abstract] [Full Text] [PDF] |
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S. Dubois, H. J. Patel, M. Zhang, T. A. Waldmann, and J. R. Muller Preassociation of IL-15 with IL-15R{alpha}-IgG1-Fc Enhances Its Activity on Proliferation of NK and CD8+/CD44high T Cells and Its Antitumor Action J. Immunol., February 15, 2008; 180(4): 2099 - 2106. [Abstract] [Full Text] [PDF] |
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S. K. Olsen, N. Ota, S. Kishishita, M. Kukimoto-Niino, K. Murayama, H. Uchiyama, M. Toyama, T. Terada, M. Shirouzu, O. Kanagawa, et al. Crystal Structure of the Interleukin-15{middle dot}Interleukin-15 Receptor {alpha} Complex: INSIGHTS INTO TRANS AND CIS PRESENTATION J. Biol. Chem., December 21, 2007; 282(51): 37191 - 37204. [Abstract] [Full Text] [PDF] |
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D. Kamimura and M. J. Bevan Naive CD8+ T cells differentiate into protective memory-like cells after IL-2 anti IL-2 complex treatment in vivo J. Exp. Med., August 6, 2007; 204(8): 1803 - 1812. [Abstract] [Full Text] [PDF] |
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S. Wittnebel, S. Da Rocha, J. Giron-Michel, A. Jalil, P. Opolon, B. Escudier, P. Validire, K. Khawam, S. Chouaib, B. Azzarone, et al. Membrane-Bound Interleukin (IL)-15 on Renal Tumor Cells Rescues Natural Killer Cells from IL-2 Starvation-Induced Apoptosis Cancer Res., June 15, 2007; 67(12): 5594 - 5599. [Abstract] [Full Text] [PDF] |
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E. Bulanova, V. Budagian, E. Duitman, Z. Orinska, H. Krause, R. Ruckert, N. Reiling, and S. Bulfone-Paus Soluble Interleukin (IL)-15R{alpha} Is Generated by Alternative Splicing or Proteolytic Cleavage and Forms Functional Complexes with IL-15 J. Biol. Chem., May 4, 2007; 282(18): 13167 - 13179. [Abstract] [Full Text] [PDF] |
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T. A. Stoklasek, K. S. Schluns, and L. Lefrancois Combined IL-15/IL-15R{alpha} Immunotherapy Maximizes IL-15 Activity In Vivo J. Immunol., November 1, 2006; 177(9): 6072 - 6080. [Abstract] [Full Text] [PDF] |
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J. Ritz Trans-presentation of IL-15 Blood, October 1, 2006; 108(7): 2135 - 2136. [Full Text] [PDF] |
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I. Lorenzen, A. J. Dingley, Y. Jacques, and J. Grotzinger The Structure of the Interleukin-15{alpha} Receptor and Its Implications for Ligand Binding J. Biol. Chem., March 10, 2006; 281(10): 6642 - 6647. [Abstract] [Full Text] [PDF] |
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