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Papers In Press, published online ahead of print October 9, 2002
J. Biol. Chem, 10.1074/jbc.M209649200
Submitted on September 19, 2002
Revised on October 8, 2002
Accepted on October 9, 2002

Scavenger receptors Class A-I/II and CD36 are the principal receptors responsible for the uptake of modified low density lipoprotein leading to lipid loading in macrophages

Vidya V. Kunjathoor, Maria Febbraio, Eugene A. Podrez, Kathryn J. Moore, Lorna Andersson, Stephanie Koehn, Jeongmi S. Rhee, Roy Silverstein, Henry F. Hoff, and Mason W. Freeman

Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114

Corresponding Author: freeman{at}frodo.mgh.harvard.edu

Modification of low-density lipoprotein (LDL) can result in the avid uptake of these lipoproteins via a family of macrophage transmembrane proteins referred to as scavenger receptors (SRs). The genetic inactivation of either of two SR family members, SR-A or CD36, has previously been shown to reduce oxidized LDL uptake in vitro and atherosclerotic lesions in mice. Several other SRs are reported to bind modified LDL, but their contribution to macrophage lipid accumulation is uncertain. We generated mice lacking both SR-A and CD36 to determine their combined impact on macrophage lipid uptake and to assess the contribution of other SRs to this process. We show that SR-A and CD36 account for 75-90% of degradation of LDL modified by acetylation or oxidation. Cholesteryl ester derived from modified lipoproteins fails to accumulate in macrophages taken from the double null mice, as assessed by histochemistry and GC-MS. These results demonstrate that SR-A and CD36 are responsible for the preponderance of modified LDL uptake in macrophages and that other scavenger receptors do not compensate for their absence.


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[Abstract] [Full Text] [PDF]

Home page
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Germ cells and fatty acids induce translocation of CD36 scavenger receptor to the plasma membrane of Sertoli cells
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[Abstract] [Full Text] [PDF]

Home page
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J. Lipid Res., May 1, 2005; 46(5): 969 - 976.
[Abstract] [Full Text] [PDF]

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J. Biochem., May 1, 2005; 137(5): 607 - 616.
[Abstract] [Full Text] [PDF]

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J. Biol. Chem., April 1, 2005; 280(13): 12888 - 12895.
[Abstract] [Full Text] [PDF]

Home page
 Cardiovasc ResHome page
M. Vinals, I. Bermudez, G. Llaverias, M. Alegret, R. M. Sanchez, M. Vazquez-Carrera, and J. C. Laguna
Aspirin increases CD36, SR-BI, and ABCA1 expression in human THP-1 macrophages
Cardiovasc Res, April 1, 2005; 66(1): 141 - 149.
[Abstract] [Full Text] [PDF]

Home page
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Direct Measurement of Nitric Oxide and Oxygen Partitioning into Liposomes and Low Density Lipoprotein
J. Biol. Chem., March 11, 2005; 280(10): 8850 - 8854.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
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J. Biol. Chem., February 4, 2005; 280(5): 3355 - 3364.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
J. D. Davies, K. L. H. Carpenter, I. R. Challis, N. L. Figg, R. McNair, D. Proudfoot, P. L. Weissberg, and C. M. Shanahan
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J. Biol. Chem., February 4, 2005; 280(5): 3911 - 3919.
[Abstract] [Full Text] [PDF]

Home page
 J. Lipid Res.Home page
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J. Lipid Res., January 1, 2005; 46(1): 11 - 20.
[Abstract] [Full Text] [PDF]

Home page
 Arterioscler. Thromb. Vasc. Bio.Home page
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Arterioscler. Thromb. Vasc. Biol., January 1, 2005; 25(1): 168 - 173.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
B. Berwin, Y. Delneste, R. V. Lovingood, S. R. Post, and S. V. Pizzo
SREC-I, a Type F Scavenger Receptor, Is an Endocytic Receptor for Calreticulin
J. Biol. Chem., December 3, 2004; 279(49): 51250 - 51257.
[Abstract] [Full Text] [PDF]

Home page
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Diabetes, December 1, 2004; 53(12): 3217 - 3225.
[Abstract] [Full Text] [PDF]

Home page
 Arterioscler. Thromb. Vasc. Bio.Home page
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Arterioscler. Thromb. Vasc. Biol., December 1, 2004; 24(12): 2333 - 2338.
[Abstract] [Full Text] [PDF]

Home page
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R. Ricci, G. Sumara, I. Sumara, I. Rozenberg, M. Kurrer, A. Akhmedov, M. Hersberger, U. Eriksson, F. R. Eberli, B. Becher, et al.
Requirement of JNK2 for Scavenger Receptor A-Mediated Foam Cell Formation in Atherogenesis
Science, November 26, 2004; 306(5701): 1558 - 1561.
[Abstract] [Full Text] [PDF]

Home page
 J. Leukoc. Biol.Home page
S. Jozefowski and L. Kobzik
Scavenger receptor A mediates H2O2 production and suppression of IL-12 release in murine macrophages
J. Leukoc. Biol., November 1, 2004; 76(5): 1066 - 1074.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
Y. Tamura, J.-i. Osuga, H. Adachi, R.-i. Tozawa, Y. Takanezawa, K. Ohashi, N. Yahagi, M. Sekiya, H. Okazaki, S. Tomita, et al.
Scavenger Receptor Expressed by Endothelial Cells I (SREC-I) Mediates the Uptake of Acetylated Low Density Lipoproteins by Macrophages Stimulated with Lipopolysaccharide
J. Biol. Chem., July 23, 2004; 279(30): 30938 - 30944.
[Abstract] [Full Text] [PDF]

Home page
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Blood, July 15, 2004; 104(2): 380 - 389.
[Abstract] [Full Text] [PDF]

Home page
 Cancer Res.Home page
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[Abstract] [Full Text] [PDF]

Home page
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Fibrillar Amyloid Protein Present in Atheroma Activates CD36 Signal Transduction
J. Biol. Chem., March 12, 2004; 279(11): 10643 - 10648.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
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J. Biol. Chem., November 28, 2003; 278(48): 47562 - 47570.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
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