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A more recent version of this article appeared on November 28, 2003
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M307700200v1
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Papers In Press, published online ahead of print September 12, 2003
J. Biol. Chem, 10.1074/jbc.M307700200
Submitted on July 16, 2003
Revised on September 10, 2003
Accepted on September 12, 2003

Compartment-specific protection of iron-sulfur proteins by superoxide dismutase

Fanis Missirlis, Jianguo Hu, Kim Kirby, Arthur J Hilliker, Tracey A Rouault, and John Phillips

Molecular Biology and Genetics, University of Guelph, Guelph, ON N1G 2W1

Corresponding Author: jphillip{at}uoguelph.ca

Iron and oxygen are essential but potentially toxic constituents of most organisms and their transport is meticulously regulated both at the cellular and systemic levels. Compartmentalization may be a homeostatic mechanism for isolating these biological


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