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FIG. 1.
Functional domains of Ebony. The 879 amino acids comprising Ebony protein possesses an NRPS-like domain organization including an adenylation (amino acid 1–572) and a thiolation domain (amino acids 573–650). Both domains can be predicted from structural data of analyzed NRPSs (34, 35). The C-terminal 230 amino acid residues do not share homologies with NRPSs and might represent a new type of domain responsible for selection of biogenic amines for the conjugation with 
-alanine.
