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Cell Biology - DNA and Chromosomes:
  • Heon Seok Kim,
  • Kyungjin Lee,
  • Sangsu Bae,
  • Jeongbin Park,
  • Chong-Kyo Lee,
  • Meehyein Kim,
  • Eunji Kim,
  • Minju Kim,
  • Seokjoong Kim,
  • Chonsaeng Kim,
  • and Jin-Soo Kim
CRISPR/Cas9-mediated gene knockout screens and target identification via whole-genome sequencing uncover host genes required for picornavirus infection J. Biol. Chem. 2017 292: 10664-. doi:10.1074/jbc.M117.782425
AUTHOR'S CHOICE
Immunology - Signal Transduction:
  • Morisada Hayakawa,
  • Hiroko Hayakawa,
  • Tsvetana Petrova,
  • Patcharee Ritprajak,
  • Ruhcha V. Sutavani,
  • Guillermina Yanek Jiménez-Andrade,
  • Yasuyo Sano,
  • Min-Kyung Choo,
  • John Seavitt,
  • Ram K. C. Venigalla,
  • Kinya Otsu,
  • Katia Georgopoulos,
  • J. Simon C. Arthur,
  • and Jin Mo Park
Loss of Functionally Redundant p38 Isoforms in T Cells Enhances Regulatory T Cell Induction J. Biol. Chem. 2017 292: 1762-. doi:10.1074/jbc.M116.764548
AUTHOR'S CHOICE
Molecular Bases of Disease - DNA and Chromosomes:
  • Tushar D. Bhagat,
  • Yiyu Zou,
  • Shizheng Huang,
  • Jihwan Park,
  • Matthew B. Palmer,
  • Caroline Hu,
  • Weijuan Li,
  • Niraj Shenoy,
  • Orsolya Giricz,
  • Gaurav Choudhary,
  • Yiting Yu,
  • Yi-An Ko,
  • María C. Izquierdo,
  • Ae Seo Deok Park,
  • Nishanth Vallumsetla,
  • Remi Laurence,
  • Robert Lopez,
  • Masako Suzuki,
  • James Pullman,
  • Justin Kaner,
  • Benjamin Gartrell,
  • A. Ari Hakimi,
  • John M. Greally,
  • Bharvin Patel,
  • Karim Benhadji,
  • Kith Pradhan,
  • Amit Verma,
  • and Katalin Susztak
Notch Pathway Is Activated via Genetic and Epigenetic Alterations and Is a Therapeutic Target in Clear Cell Renal Cancer J. Biol. Chem. 2017 292: 837-. doi:10.1074/jbc.M116.745208
Cell Biology - Signal Transduction:
  • Hyun Lee,
  • Jung-Jin Park,
  • Nga Nguyen,
  • Jun Sub Park,
  • Jin Hong,
  • Seung-Hyeob Kim,
  • Woon Young Song,
  • Hak Joong Kim,
  • Kwangman Choi,
  • Sungchan Cho,
  • Jae-Seon Lee,
  • Bong-Woo Kim,
  • and Young-Gyu Ko
MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) Interaction Disruptor Sensitizes Insulin Signaling in Skeletal Muscle J. Biol. Chem. 2016 291: 26627-. doi:10.1074/jbc.M116.754424
Gene Regulation - Immunology:
  • Seong-Hwan Park,
  • Juil Kim,
  • Mira Yu,
  • Jae-Hong Park,
  • Yong Sik Kim,
  • and Yuseok Moon
Epithelial Cholesterol Deficiency Attenuates Human Antigen R-linked Pro-inflammatory Stimulation via an SREBP2-linked Circuit J. Biol. Chem. 2016 291: 24641-. doi:10.1074/jbc.M116.723973
Cell Biology - Signal Transduction:
  • Timothy S. Kountz,
  • Kyung-Soon Lee,
  • Stacey Aggarwal-Howarth,
  • Elizabeth Curran,
  • Ji-Min Park,
  • Dorathy-Ann Harris,
  • Aaron Stewart,
  • Joseph Hendrickson,
  • Nathan D. Camp,
  • Alejandro Wolf-Yadlin,
  • Edith H. Wang,
  • John D. Scott,
  • and Chris Hague
Endogenous N-terminal Domain Cleavage Modulates α1D-Adrenergic Receptor Pharmacodynamics J. Biol. Chem. 2016 291: 18210-. doi:10.1074/jbc.M116.729517
Cell Biology - Signal Transduction:
  • Hee Jin Chung,
  • Ji Eun Park,
  • Nam Soo Lee,
  • Hongtae Kim,
  • and Chang-Young Jang
Phosphorylation of Astrin Regulates Its Kinetochore Function J. Biol. Chem. 2016 291: 17579-. doi:10.1074/jbc.M115.712745
Molecular Bases of Disease - Neurobiology:
  • John Park,
  • Yanhui Peter Yu,
  • Chun-Yi Zhou,
  • Kang-Wu Li,
  • Dongqing Wang,
  • Eric Chang,
  • Doo-Sik Kim,
  • Benjamin Vo,
  • Xia Zhang,
  • Nian Gong,
  • Kelli Sharp,
  • Oswald Steward,
  • Iuliia Vitko,
  • Edward Perez-Reyes,
  • Cagla Eroglu,
  • Ben Barres,
  • Frank Zaucke,
  • Guoping Feng,
  • and Z. David Luo
Central Mechanisms Mediating Thrombospondin-4-induced Pain States J. Biol. Chem. 2016 291: 13335-. doi:10.1074/jbc.M116.723478
Gene Regulation - Molecular Bases of Disease:
  • Pyoung Oh Yoon,
  • Jin Wook Park,
  • Chang-Min Lee,
  • Sung Hwan Kim,
  • Han-Na Kim,
  • Youngho Ko,
  • Seon Joo Bae,
  • Sungil Yun,
  • Jun Hong Park,
  • Taewoo Kwon,
  • Woo Seok Kim,
  • Jiyoung Lee,
  • Qing Lu,
  • Hye-Ryun Kang,
  • Won-Kyung Cho,
  • Jack A. Elias,
  • Joo-Sung Yang,
  • Han-Oh Park,
  • Kyuhong Lee,
  • and Chun Geun Lee
Self-assembled Micelle Interfering RNA for Effective and Safe Targeting of Dysregulated Genes in Pulmonary Fibrosis J. Biol. Chem. 2016 291: 6433-. doi:10.1074/jbc.M115.693671
Glycobiology and Extracellular Matrices - Signal Transduction:
  • Mi-Jung Kwon,
  • Jisu Park,
  • Sinae Jang,
  • Chi-Yong Eom,
  • and Eok-Soo Oh
The Conserved Phenylalanine in the Transmembrane Domain Enhances Heteromeric Interactions of Syndecans J. Biol. Chem. 2016 291: 872-. doi:10.1074/jbc.M115.685040

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