Decatenation of kinetoplast DNA by topoisomerases.

  1. J C Marini,
  2. K G Miller and
  3. P T Englund

    Abstract

    Kinetoplast DNA is the mitochondrial DNA of trypanosomatids such as Crithidia fasciculata. This DNA is in the form of networks containing thousands of DNA circles which are apparently catenated (interlocked). Some topoisomerases, such as T4 phage topoisomerase and DNA gyrase, catalyze a decatenation of the networks to form individual covalently closed circles.

    « Previous | Next Article »Table of Contents

    This Article

    1. June 10, 1980 The Journal of Biological Chemistry, 255, 4976-4979.
    1. » AbstractFree
    2. Full Text (PDF)Free

    This Week's Issue

    1. December 4, 2009, 284 (49)
    1. Current Issue
    1. Alert me to new issues of JBC
    • Advertisement
    • Advertisement
    Advertisement