Cyclooxygenase-2-derived prostaglandin E2 promotes human cholangiocarcinoma cell growth and invasion through EP1 receptor-mediated activation of the epidermal growth factor receptor and Akt.
VOLUME 280 (2005) PAGES 24053–24063
This article has been retracted by the publisher. An investigation at the University of Pittsburgh found that the EGFR bands in Fig. 2 appeared to be similar to the Akt bands in Fig. 4, and the blots in Fig. 8C were used to represent the results of a different experiment in Fig. 9B of a different article: Han, C., Demetris, A. J., Stolz, D. B., Xu, L., Lim, K., and Wu, T. (2006) Modulation of Stat3 activation by the cytosolic phospholipase A2α and cyclooxygenase-2-controlled prostaglandin E2 signaling pathway. J. Biol. Chem. 281, 24831–24846.
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