IKBKE protein activates Akt independent of phosphatidylinositol 3-kinase/PDK1/mTORC2 and the pleckstrin homology domain to sustain malignant transformation.

VOLUME 286 (2011) PAGES 37389–37398

This article has been withdrawn by the authors. The same data were used to represent different experimental conditions. Specifically, the Myc-IKBKE immunoblot from Fig. 4B was reused as the Myc-IKBKE immunoblot in Fig. 4C. The IKBKE immunoblot from Ikbke^−/− MEFs treated with EGF was reused in the IKBKE panel from Ikbke^−/− MEFs treated with insulin in supplemental Fig. S5A. In supplemental Fig. S5B, the pAkt-T308 immunoblot from Ikbke^−/− MEFs treated with glucose was reused in the pAkt-T308 panel from wild type MEFs treated with amino acid. The authors state that the overall conclusions of the study are not affected.

• © 2016 by The American Society for Biochemistry and Molecular Biology, Inc.