Minireviews

Edith Wilson Miles, Sangkee Rhee, and David R. Davies

The Molecular Basis of Substrate Channeling
1999 274: 12193-12196. [Full Text] [PDF]

Communications

Tomohiko Urano, Hideki Yashiroda, Masatoshi Muraoka, Kiyoko Tanaka, Takayuki Hosoi, Satoshi Inoue, Yasuyoshi Ouchi, Keiji Tanaka, and Hideo Toyoshima

p57^Kip2 Is Degraded through the Proteasome in Osteoblasts Stimulated to Proliferation by Transforming Growth Factor 1
1999 274: 12197-12200. [Abstract] [Full Text] [PDF]

Shisheng Li and Michael J. Smerdon

Base Excision Repair of N-Methylpurines in a Yeast Minichromosome. EFFECTS OF TRANSCRIPTION, DNA SEQUENCE, AND NUCLEOSOME POSITIONING
1999 274: 12201-12204. [Abstract] [Full Text] [PDF]

Mona Trempe Norcum and J. David Dignam

Immunoelectron Microscopic Localization of Glutamyl-/ Prolyl-tRNA Synthetase within the Eukaryotic Multisynthetase Complex
1999 274: 12205-12208. [Abstract] [Full Text] [PDF]

Katalin Szabó, Gergely Szakács, Tamás Hegedus, and Balázs Sarkadi

Nucleotide Occlusion in the Human Cystic Fibrosis Transmembrane Conductance Regulator. DIFFERENT PATTERNS IN THE TWO NUCLEOTIDE BINDING DOMAINS
1999 274: 12209-12212. [Abstract] [Full Text] [PDF]

Gábor Bánhegyi, Lorenzo Lusini, Ferenc Puskás, Ranieri Rossi, Rosella Fulceri, László Braun, Valéria Mile, Paolo di Simplicio, József Mandl, and Angelo Benedetti

Preferential Transport of Glutathione versus Glutathione Disulfide in Rat Liver Microsomal Vesicles
1999 274: 12213-12216. [Abstract] [Full Text] [PDF]

Carbohydrates, Lipids, and Other Natural Products

Lolita O. Zamir, Anastasia Nikolakakis, Liren Huang, Patrick St-Pierre, Françoise Sauriol, Salvatore Sparace, and Orval Mamer

Biosynthesis of 3-Acetyldeoxynivalenol and Sambucinol. IDENTIFICATION OF THE TWO OXYGENATION STEPS AFTER TRICHODIENE
1999 274: 12269-12277. [Abstract] [Full Text] [PDF]

Frank Petersen, Ernst Brandt, Ulf Lindahl, and Dorothe Spillmann

Characterization of a Neutrophil Cell Surface Glycosaminoglycan That Mediates Binding of Platelet Factor 4
1999 274: 12376-12382. [Abstract] [Full Text] [PDF]

Soichiro Isshiki, Akira Togayachi, Takashi Kudo, Shoko Nishihara, Masahiko Watanabe, Tetsuro Kubota, Masaki Kitajima, Norihiko Shiraishi, Katsutoshi Sasaki, Toshiwo Andoh, and Hisashi Narimatsu

Cloning, Expression, and Characterization of a Novel UDP-galactose:-N-Acetylglucosamine 1,3-Galactosyltransferase (3Gal-T5) Responsible for Synthesis of Type 1 Chain in Colorectal and Pancreatic Epithelia and Tumor Cells Derived Therefrom
1999 274: 12499-12507. [Abstract] [Full Text] [PDF]

Paul Anthony Majcherczyk, Hanno Langen, Didier Heumann, Michael Fountoulakis, Michel Pierre Glauser, and Philippe Moreillon

Digestion of Streptococcus pneumoniae Cell Walls with Its Major Peptidoglycan Hydrolase Releases Branched Stem Peptides Carrying Proinflammatory Activity
1999 274: 12537-12543. [Abstract] [Full Text] [PDF]

Cell Biology and Metabolism

Hiroyuki Shinohara, María A. Balboa, Christina A. Johnson, Jesús Balsinde, and Edward A. Dennis

Regulation of Delayed Prostaglandin Production in Activated P388D₁ Macrophages by Group IV Cytosolic and Group V Secretory Phospholipase A₂s
1999 274: 12263-12268. [Abstract] [Full Text] [PDF]

Séverine Groh, Isabelle Marty, Michela Ottolia, Gianfranco Prestipino, Agnès Chapel, Michel Villaz, and Michel Ronjat

Functional Interaction of the Cytoplasmic Domain of Triadin with the Skeletal Ryanodine Receptor
1999 274: 12278-12283. [Abstract] [Full Text] [PDF]

Akira Togawa, Naoko Morinaga, Masahito Ogasawara, Joel Moss, and Martha Vaughan

Purification and Cloning of a Brefeldin A-inhibited Guanine Nucleotide-exchange Protein for ADP-ribosylation Factors
1999 274: 12308-12315. [Abstract] [Full Text] [PDF]

Oliver Vögler, Bettina Nolte, Matthias Voss, Martina Schmidt, Karl H. Jakobs, and Chris J. van Koppen

Regulation of Muscarinic Acetylcholine Receptor Sequestration and Function by -Arrestin
1999 274: 12333-12338. [Abstract] [Full Text] [PDF]

David C. Budd, Angela Rae, and Andrew B. Tobin

Activation of the Mitogen-activated Protein Kinase Pathway by a G_q/11-coupled Muscarinic Receptor Is Independent of Receptor Internalization
1999 274: 12355-12360. [Abstract] [Full Text] [PDF]

Heinz R. Reiske, Shu-Chen Kao, Leslie A. Cary, Jun-Lin Guan, Jui-Fen Lai, and Hong-Chen Chen

Requirement of Phosphatidylinositol 3-Kinase in Focal Adhesion Kinase-promoted Cell Migration
1999 274: 12361-12366. [Abstract] [Full Text] [PDF]

Hua Tang, Zhizhuang Joe Zhao, Xin-Yun Huang, Erwin J. Landon, and Tadashi Inagami

Fyn Kinase-directed Activation of SH2 Domain-containing Protein-tyrosine Phosphatase SHP-2 by G_i Protein-coupled Receptors in Madin-Darby Canine Kidney Cells
1999 274: 12401-12407. [Abstract] [Full Text] [PDF]

John R. Forbes, Gloria Hsi, and Diane W. Cox

Role of the Copper-binding Domain in the Copper Transport Function of ATP7B, the P-type ATPase Defective in Wilson Disease
1999 274: 12408-12413. [Abstract] [Full Text] [PDF]

Barbara Valentinis, Gaetano Romano, Francesca Peruzzi, Andrea Morrione, Marco Prisco, Silvia Soddu, Barbara Cristofanelli, Ada Sacchi, and Renato Baserga

Growth and Differentiation Signals by the Insulin-like Growth Factor 1 Receptor in Hemopoietic Cells Are Mediated through Different Pathways
1999 274: 12423-12430. [Abstract] [Full Text] [PDF]

Gustavo Pacheco-Rodriguez, Walter A. Patton, Ronald Adamik, Hwan-Soo Yoo, Fang-Jen S. Lee, Gui-Feng Zhang, Joel Moss, and Martha Vaughan

Structural Elements of ADP-ribosylation Factor 1 Required for Functional Interaction with Cytohesin-1
1999 274: 12438-12444. [Abstract] [Full Text] [PDF]

Kent A. Fagan, Thomas C. Rich, Shawna Tolman, Jerome Schaack, Jeffrey W. Karpen, and Dermot M. F. Cooper

Adenovirus-mediated Expression of an Olfactory Cyclic Nucleotide-gated Channel Regulates the Endogenous Ca²⁺-inhibitable Adenylyl Cyclase in C6-2B Glioma Cells
1999 274: 12445-12453. [Abstract] [Full Text] [PDF]

Carole Rovère, José Luis, Jean-Claude Lissitzky, Ajoy Basak, Jacques Marvaldi, Michel Chrétien, and Nabil G. Seidah

The RGD Motif and the C-terminal Segment of Proprotein Convertase 1 Are Critical for Its Cellular Trafficking but Not for Its Intracellular Binding to Integrin ₅₁
1999 274: 12461-12467. [Abstract] [Full Text] [PDF]

Nobuaki Maeda, Keiko Ichihara-Tanaka, Terutoshi Kimura, Kenji Kadomatsu, Takashi Muramatsu, and Masaharu Noda

A Receptor-like Protein-tyrosine Phosphatase PTP/RPTP Binds a Heparin-binding Growth Factor Midkine. INVOLVEMENT OF ARGININE 78 OF MIDKINE IN THE HIGH AFFINITY BINDING TO PTP
1999 274: 12474-12479. [Abstract] [Full Text] [PDF]

Yolanda Hernando, Andrew T. Carter, Adrian Parr, Bjarne Hove-Jensen, and Michael Schweizer

Genetic Analysis and Enzyme Activity Suggest the Existence of More Than One Minimal Functional Unit Capable of Synthesizing Phosphoribosyl Pyrophosphate in Saccharomyces cerevisiae
1999 274: 12480-12487. [Abstract] [Full Text] [PDF]

Cheng He, Hailin Zhang, Tooraj Mirshahi, and Diomedes E. Logothetis

Identification of a Potassium Channel Site That Interacts with G Protein Subunits to Mediate Agonist-induced Signaling
1999 274: 12517-12524. [Abstract] [Full Text] [PDF]

Kieran F. Harvey, Anuwat Dinudom, Permsak Komwatana, Corina N. Jolliffe, Margot L. Day, Gayathri Parasivam, David I. Cook, and Sharad Kumar

All Three WW Domains of Murine Nedd4 Are Involved in the Regulation of Epithelial Sodium Channels by Intracellular Na⁺
1999 274: 12525-12530. [Abstract] [Full Text] [PDF]

Monique R. Heitmeier, Anna L. Scarim, and John A. Corbett

Double-stranded RNA Inhibits -Cell Function and Induces Islet Damage by Stimulating -Cell Production of Nitric Oxide
1999 274: 12531-12536. [Abstract] [Full Text] [PDF]

Thomas Sternsdorf, Kirsten Jensen, Berthold Reich, and Hans Will

The Nuclear Dot Protein Sp100, Characterization of Domains Necessary for Dimerization, Subcellular Localization, and Modification by Small Ubiquitin-like Modifiers
1999 274: 12555-12566. [Abstract] [Full Text] [PDF]

Ricky Malhotra and Frank C. Brosius III

Glucose Uptake and Glycolysis Reduce Hypoxia-induced Apoptosis in Cultured Neonatal Rat Cardiac Myocytes
1999 274: 12567-12575. [Abstract] [Full Text] [PDF]

Pierre Maechler, Eleanor D. Kennedy, Elisabeth Sebö, Angela Valeva, Tullio Pozzan, and Claes B. Wollheim

Secretagogues Modulate the Calcium Concentration in the Endoplasmic Reticulum of Insulin-secreting Cells. STUDIES IN AEQUORIN-EXPRESSING INTACT AND PERMEABILIZED INS-1 CELLS
1999 274: 12583-12592. [Abstract] [Full Text] [PDF]

Nobuhiro Shimizu, Ryota Itoh, Yoko Hirono, Hidenori Otera, Kamran Ghaedi, Keita Tateishi, Shigehiko Tamura, Kanji Okumoto, Tomoyuki Harano, Satoru Mukai, and Yukio Fujiki

The Peroxin Pex14p. cDNA CLONING BY FUNCTIONAL COMPLEMENTATION ON A CHINESE HAMSTER OVARY CELL MUTANT, CHARACTERIZATION, AND FUNCTIONAL ANALYSIS
1999 274: 12593-12604. [Abstract] [Full Text] [PDF]

Toshiaki Yujiri, Gary R. Fanger, Timothy P. Garrington, Thomas K. Schlesinger, Spencer Gibson, and Gary L. Johnson

MEK Kinase 1 (MEKK1) Transduces c-Jun NH₂-terminal Kinase Activation in Response to Changes in the Microtubule Cytoskeleton
1999 274: 12605-12610. [Abstract] [Full Text] [PDF]

Nives Zimmermann, Juliana J. Conkright, and Marc E. Rothenberg

CC Chemokine Receptor-3 Undergoes Prolonged Ligand-induced Internalization
1999 274: 12611-12618. [Abstract] [Full Text] [PDF]

Masato Hasegawa, Ana Cuenda, Maria Grazia Spillantini, Gareth M. Thomas, Valérie Buée-Scherrer, Philip Cohen, and Michel Goedert

Stress-activated Protein Kinase-3 Interacts with the PDZ Domain of 1-Syntrophin. A MECHANISM FOR SPECIFIC SUBSTRATE RECOGNITION
1999 274: 12626-12631. [Abstract] [Full Text] [PDF]

Cynthia M. Smas, Li Chen, Ling Zhao, Maria-Jesus Latasa, and Hei Sook Sul

Transcriptional Repression of pref-1 by Glucocorticoids Promotes 3T3-L1 Adipocyte Differentiation
1999 274: 12632-12641. [Abstract] [Full Text] [PDF]

Stéphane O. Cociancich, Soon S. Park, David A. Fidock, and Mohammed Shahabuddin

Vesicular ATPase-overexpressing Cells Determine the Distribution of Malaria Parasite Oocysts on the Midguts of Mosquitoes
1999 274: 12650-12655. [Abstract] [Full Text] [PDF]

Luigi Puglielli, Elisabet C. Mandon, and Carlos B. Hirschberg

Identification, Purification, and Characterization of the Rat Liver Golgi Membrane ATP Transporter
1999 274: 12665-12669. [Abstract] [Full Text] [PDF]

Li Ni, Thomas S. Heard, and Henry Weiner

In Vivo Mitochondrial Import. A COMPARISON OF LEADER SEQUENCE CHARGE AND STRUCTURAL RELATIONSHIPS WITH THE IN VITRO MODEL RESULTING IN EVIDENCE FOR CO-TRANSLATIONAL IMPORT
1999 274: 12685-12691. [Abstract] [Full Text] [PDF]

Daniela Volonté, Ferruccio Galbiati, Shengwen Li, Kazutoshi Nishiyama, Takashi Okamoto, and Michael P. Lisanti

Flotillins/Cavatellins Are Differentially Expressed in Cells and Tissues and Form a Hetero-oligomeric Complex with Caveolins in Vivo. CHARACTERIZATION AND EPITOPE-MAPPING OF A NOVEL FLOTILLIN-1 MONOCLONAL ANTIBODY PROBE
1999 274: 12702-12709. [Abstract] [Full Text] [PDF]

Hiroshi Hayashi, Luigi De Bellis, Adriana Ciurli, Maki Kondo, Makoto Hayashi, and Mikio Nishimura

A Novel Acyl-CoA Oxidase That Can Oxidize Short-chain Acyl-CoA in Plant Peroxisomes
1999 274: 12715-12721. [Abstract] [Full Text] [PDF]

Atef N. Hanna, Edmond Y. W. Chan, James Xu, James C. Stone, and David N. Brindley

A Novel Pathway for Tumor Necrosis Factor- and Ceramide Signaling Involving Sequential Activation of Tyrosine Kinase, p21^ras, and Phosphatidylinositol 3-Kinase
1999 274: 12722-12729. [Abstract] [Full Text] [PDF]

Anne Pizard, Andree Blaukat, Werner Müller-Esterl, François Alhenc-Gelas, and Rabary M. Rajerison

Bradykinin-induced Internalization of the Human B₂ Receptor Requires Phosphorylation of Three Serine and Two Threonine Residues at Its Carboxyl Tail
1999 274: 12738-12747. [Abstract] [Full Text] [PDF]

Gang Chen, Shyng-Shiou F. Yuan, Wei Liu, Yang Xu, Kelly Trujillo, Binwei Song, Feng Cong, Stephen P. Goff, Yun Wu, Ralph Arlinghaus, David Baltimore, Paul J. Gasser, Min S. Park, Patrick Sung, and Eva Y.-H. P. Lee

Radiation-induced Assembly of Rad51 and Rad52 Recombination Complex Requires ATM and c-Abl
1999 274: 12748-12752. [Abstract] [Full Text] [PDF]

Ian N. Fleming, Cassondra M. Elliott, F. Gregory Buchanan, C. Peter Downes, and John H. Exton

Ca²⁺/Calmodulin-dependent Protein Kinase II Regulates Tiam1 by Reversible Protein Phosphorylation
1999 274: 12753-12758. [Abstract] [Full Text] [PDF]

Roberta Vezza, Aida Habib, and Garret A. FitzGerald

Differential Signaling by the Thromboxane Receptor Isoforms via the Novel GTP-binding Protein, G_h
1999 274: 12774-12779. [Abstract] [Full Text] [PDF]

Paul A. Calvo, David W. Frank, Bert M. Bieler, Joanne F. Berson, and Michael S. Marks

A Cytoplasmic Sequence in Human Tyrosinase Defines a Second Class of Di-leucine-based Sorting Signals for Late Endosomal and Lysosomal Delivery
1999 274: 12780-12789. [Abstract] [Full Text] [PDF]

Laiqiang Huang, Teresa Y. W. Wong, Richard C. C. Lin, and Heinz Furthmayr

Replacement of Threonine 558, a Critical Site of Phosphorylation of Moesin in Vivo, with Aspartate Activates F-actin Binding of Moesin. REGULATION BY CONFORMATIONAL CHANGE
1999 274: 12803-12810. [Abstract] [Full Text] [PDF]

Weiqin Lu, Yongde Luo, Mikio Kan, and Wallace L. McKeehan

Fibroblast Growth Factor-10. A SECOND CANDIDATE STROMAL TO EPITHELIAL CELL ANDROMEDIN IN PROSTATE
1999 274: 12827-12834. [Abstract] [Full Text] [PDF]

DanHui Wang, LuZhe Sun, Elizabeth Zborowska, James K. V. Willson, Jiangen Gong, Janaki Verraraghavan, and Michael G. Brattain

Control of Type II Transforming Growth Factor- Receptor Expression by Integrin Ligation
1999 274: 12840-12847. [Abstract] [Full Text] [PDF]

Sraboni Ghose, Hartmut Porzig, and Kurt Baltensperger

Induction of Erythroid Differentiation by Altered G₁₆ Activity as Detected by a Reporter Gene Assay in MB-02 Cells
1999 274: 12848-12854. [Abstract] [Full Text] [PDF]

Xiangjun Zhou, Jian Liao, Lanrong Hu, Li Feng, and M. Bishr Omary

Characterization of the Major Physiologic Phosphorylation Site of Human Keratin 19 and Its Role in Filament Organization
1999 274: 12861-12866. [Abstract] [Full Text] [PDF]

Jin Wang and Ann L. White

6-Aminohexanoic Acid as a Chemical Chaperone for Apolipoprotein(a)
1999 274: 12883-12889. [Abstract] [Full Text] [PDF]

Keith R. Laderoute, Holly L. Mendonca, Joy M. Calaoagan, A. Merrill Knapp, Amato J. Giaccia, and Philip J. S. Stork

Mitogen-activated Protein Kinase Phosphatase-1 (MKP-1) Expression Is Induced by Low Oxygen Conditions Found in Solid Tumor Microenvironments. A CANDIDATE MKP FOR THE INACTIVATION OF HYPOXIA-INDUCIBLE STRESS-ACTIVATED PROTEIN KINASE/c-Jun N-TERMINAL PROTEIN KINASE ACTIVITY
1999 274: 12890-12897. [Abstract] [Full Text] [PDF]

Michele Marinò, Gang Zheng, and Robert T. McCluskey

Megalin (gp330) Is an Endocytic Receptor for Thyroglobulin on Cultured Fisher Rat Thyroid Cells
1999 274: 12898-12904. [Abstract] [Full Text] [PDF]

Masato Ogata, Tsuyoshi Takada, Yoshiko Mori, Masatsugu Oh-hora, Yohzo Uchida, Atsushi Kosugi, Kensuke Miyake, and Toshiyuki Hamaoka

Effects of Overexpression of PTP36, a Putative Protein Tyrosine Phosphatase, on Cell Adhesion, Cell Growth, and Cytoskeletons in HeLa Cells
1999 274: 12905-12909. [Abstract] [Full Text] [PDF]

David W. Cooke and M. Daniel Lane

The Transcription Factor Nuclear Factor I Mediates Repression of the GLUT4 Promoter by Insulin
1999 274: 12917-12924. [Abstract] [Full Text] [PDF]

Gadiparthi N. Rao, Nageswara R. Madamanchi, Manjiri Lele, Laxmisilpa Gadiparthi, Anne-Claude Gingras, Thomas E. Eling, and Nahum Sonenberg

A Potential Role for Extracellular Signal-regulated Kinases in Prostaglandin F₂-induced Protein Synthesis in Smooth Muscle Cells
1999 274: 12925-12932. [Abstract] [Full Text] [PDF]

Oliver Eickelberg, Andreas Pansky, Rainer Mussmann, Michel Bihl, Michael Tamm, Pius Hildebrand, Andre P. Perruchoud, and Michael Roth

Transforming Growth Factor-1 Induces Interleukin-6 Expression via Activating Protein-1 Consisting of JunD Homodimers in Primary Human Lung Fibroblasts
1999 274: 12933-12938. [Abstract] [Full Text] [PDF]

Enzymology

Gregory A. Hunter and Gloria C. Ferreira

Pre-steady-state Reaction of 5-Aminolevulinate Synthase. EVIDENCE FOR A RATE-DETERMINING PRODUCT RELEASE
1999 274: 12222-12228. [Abstract] [Full Text] [PDF]

Daniel Nelson, Jan Potempa, Tomasz Kordula, and James Travis

Purification and Characterization of a Novel Cysteine Proteinase (Periodontain) from Porphyromonas gingivalis. EVIDENCE FOR A ROLE IN THE INACTIVATION OF HUMAN ₁-PROTEINASE INHIBITOR
1999 274: 12245-12251. [Abstract] [Full Text] [PDF]

Fabrice Dupuy, Jean-Michel Petit, Rosella Mollicone, Rafael Oriol, Raymond Julien, and Abderrahman Maftah

A Single Amino Acid in the Hypervariable Stem Domain of Vertebrate 1,3/1,4-Fucosyltransferases Determines the Type 1/Type 2 Transfer. CHARACTERIZATION OF ACCEPTOR SUBSTRATE SPECIFICITY OF THE LEWIS ENZYME BY SITE-DIRECTED MUTAGENESIS
1999 274: 12257-12262. [Abstract] [Full Text] [PDF]

Hilde Kristin Høidal, Helga Ertesvåg, Gudmund Skjåk-Bræk, Bjørn Torger Stokke, and Svein Valla

The Recombinant Azotobacter vinelandii Mannuronan C-5-Epimerase AlgE4 Epimerizes Alginate by a Nonrandom Attack Mechanism
1999 274: 12316-12322. [Abstract] [Full Text] [PDF]

Feng Xu, Amy E. Palmer, Debbie S. Yaver, Randy M. Berka, Gregory A. Gambetta, Stephen H. Brown, and Edward I. Solomon

Targeted Mutations in a Trametes villosa Laccase. AXIAL PERTURBATIONS OF THE T1 COPPER
1999 274: 12372-12375. [Abstract] [Full Text] [PDF]

Valerie Sinniger, R. Elizabeth Merton, Pere Fabregas, Jordi Felez, and Colin Longstaff

Regulation of Tissue Plasminogen Activator Activity by Cells. DOMAINS RESPONSIBLE FOR BINDING AND MECHANISM OF STIMULATION
1999 274: 12414-12422. [Abstract] [Full Text] [PDF]

Frank Pfennig, Florian Schauwecker, and Ullrich Keller

Molecular Characterization of the Genes of Actinomycin Synthetase I and of a 4-Methyl-3-hydroxyanthranilic Acid Carrier Protein Involved in the Assembly of the Acylpeptide Chain of Actinomycin in Streptomyces
1999 274: 12508-12516. [Abstract] [Full Text] [PDF]

Clemens Steegborn, Tim Clausen, Peter Sondermann, Uwe Jacob, Michael Worbs, Snezan Marinkovic, Robert Huber, and Markus C. Wahl

Kinetics and Inhibition of Recombinant Human Cystathionine -Lyase. TOWARD THE RATIONAL CONTROL OF TRANSSULFURATION
1999 274: 12675-12684. [Abstract] [Full Text] [PDF]

Tatsuya Morimoto, Koji Hasegawa, Satoshi Kaburagi, Tsuyoshi Kakita, Hiroshi Masutani, Richard N. Kitsis, Akira Matsumori, and Shigetake Sasayama

GATA-5 Is Involved in Leukemia Inhibitory Factor-responsive Transcription of the -Myosin Heavy Chain Gene in Cardiac Myocytes
1999 274: 12811-12818. [Abstract] [Full Text] [PDF]

Todd B. Parsley, Christopher T. Cornell, and Bert L. Semler

Modulation of the RNA Binding and Protein Processing Activities of Poliovirus Polypeptide 3CD by the Viral RNA Polymerase Domain
1999 274: 12867-12876. [Abstract] [Full Text] [PDF]

Membranes and Bioenergetics

Alex G. Therien, Steven J. D. Karlish, and Rhoda Blostein

Expression and Functional Role of the  Subunit of the Na,K-ATPase in Mammalian Cells
1999 274: 12252-12256. [Abstract] [Full Text] [PDF]

Guoquan Wang, Shusen Li, Hainan Lin, Erich E. Brumbaugh, and Ching-hsien Huang

Effects of Various Numbers and Positions of cis Double Bonds in the sn-2 Acyl Chain of Phosphatidylethanolamine on the Chain-melting Temperature
1999 274: 12289-12299. [Abstract] [Full Text] [PDF]

Mikhail Bogdanov, Masato Umeda, and William Dowhan

Phospholipid-assisted Refolding of an Integral Membrane Protein. MINIMUM STRUCTURAL FEATURES FOR PHOSPHATIDYLETHANOLAMINE TO ACT AS A MOLECULAR CHAPERONE
1999 274: 12339-12345. [Abstract] [Full Text] [PDF]

Denise Walker, Delphine Bichet, Sandrine Geib, Emiko Mori, Véronique Cornet, Terry P. Snutch, Yasuo Mori, and Michel De Waard

A New  Subtype-specific Interaction in _1A Subunit Controls P/Q-type Ca²⁺ Channel Activation
1999 274: 12383-12390. [Abstract] [Full Text] [PDF]

Jeffery R. Williams, James W. Sharp, Vijaya G. Kumari, Martin Wilson, and John A. Payne

The Neuron-specific K-Cl Cotransporter, KCC2. ANTIBODY DEVELOPMENT AND INITIAL CHARACTERIZATION OF THE PROTEIN
1999 274: 12656-12664. [Abstract] [Full Text] [PDF]

Nicole Andrejewski, Eeva-Liisa Punnonen, Gundula Guhde, Yoshitaka Tanaka, Renate Lüllmann-Rauch, Dieter Hartmann, Kurt von Figura, and Paul Saftig

Normal Lysosomal Morphology and Function in LAMP-1-deficient Mice
1999 274: 12692-12701. [Abstract] [Full Text] [PDF]

Takahiro M. Ishii, Makoto Takano, Lai-Hua Xie, Akinori Noma, and Harunori Ohmori

Molecular Characterization of the Hyperpolarization-activated Cation Channel in Rabbit Heart Sinoatrial Node
1999 274: 12835-12839. [Abstract] [Full Text] [PDF]

Douglas L. Hogue, Lilli Kerby, and Victor Ling

A Mammalian Lysosomal Membrane Protein Confers Multidrug Resistance upon Expression in Saccharomyces cerevisiae
1999 274: 12877-12882. [Abstract] [Full Text] [PDF]

Nucleic Acids, Protein Synthesis, and Molecular Genetics

Igor Goncharov, Zsofia Palfi, Albrecht Bindereif, and Shulamit Michaeli

Purification of the Spliced Leader Ribonucleoprotein Particle from Leptomonas collosoma Revealed the Existence of an Sm Protein in Trypanosomes. CLONING THE SmE HOMOLOGUE
1999 274: 12217-12221. [Abstract] [Full Text] [PDF]

Chuanshu Huang, Wei-Ya Ma, Aaron Maxiner, Yi Sun, and Zigang Dong

p38 Kinase Mediates UV-induced Phosphorylation of p53 Protein at Serine 389
1999 274: 12229-12235. [Abstract] [Full Text] [PDF]

George W. Rogers Jr., Nancy J. Richter, and William C. Merrick

Biochemical and Kinetic Characterization of the RNA Helicase Activity of Eukaryotic Initiation Factor 4A
1999 274: 12236-12244. [Abstract] [Full Text] [PDF]

Elizabeth R. Jamieson, Matthew P. Jacobson, Carmen M. Barnes, Christine S. Chow, and Stephen J. Lippard

Structural and Kinetic Studies of a Cisplatin-modified DNA Icosamer Binding to HMG1 Domain B
1999 274: 12346-12354. [Abstract] [Full Text] [PDF]

Yange Zhang, Martin B. Dickman, and Clinton Jones

The Mycotoxin Fumonisin B₁ Transcriptionally Activates the p21 Promoter through a cis-Acting Element Containing Two Sp1 Binding Sites
1999 274: 12367-12371. [Abstract] [Full Text] [PDF]

William P. Long, Xi Chen, and Gary H. Perdew

Protein Kinase C Modulates Aryl Hydrocarbon Receptor Nuclear Translocator Protein-mediated Transactivation Potential in a Dimer Context
1999 274: 12391-12400. [Abstract] [Full Text] [PDF]

Raouf Sayegh, Scott D. Auerbach, Xiang Li, Randy W. Loftus, Russell F. Husted, John B. Stokes, and Christie P. Thomas

Glucocorticoid Induction of Epithelial Sodium Channel Expression in Lung and Renal Epithelia Occurs via trans-Activation of a Hormone Response Element in the 5'-Flanking Region of the Human Epithelial Sodium Channel  Subunit Gene
1999 274: 12431-12437. [Abstract] [Full Text] [PDF]

Leah E. Mechanic, Mark C. Hall, and Steven W. Matson

Escherichia coli DNA Helicase II Is Active as a Monomer
1999 274: 12488-12498. [Abstract] [Full Text] [PDF]

Maria E. Kitchens, Antonia M. Forsthoefel, Zubaid Rafique, H. Trent Spencer, and Franklin G. Berger

Ligand-mediated Induction of Thymidylate Synthase Occurs by Enzyme Stabilization. IMPLICATIONS FOR AUTOREGULATION OF TRANSLATION
1999 274: 12544-12547. [Abstract] [Full Text] [PDF]

Angel Raya, Fernando Revert, Samuel Navarro, and Juan Saus

Characterization of a Novel Type of Serine/Threonine Kinase That Specifically Phosphorylates the Human Goodpasture Antigen
1999 274: 12642-12649. [Abstract] [Full Text] [PDF]

Deborah A. Mason, J. Donald Moore, Stuart A. Green, and Stephen B. Liggett

A Gain-of-function Polymorphism in a G-protein Coupling Domain of the Human ₁-Adrenergic Receptor
1999 274: 12670-12674. [Abstract] [Full Text] [PDF]

Claudine Boiziau, Eric Dausse, Ludmila Yurchenko, and Jean-Jacques Toulmé

DNA Aptamers Selected Against the HIV-1 trans-Activation-responsive RNA Element Form RNA-DNA Kissing Complexes
1999 274: 12730-12737. [Abstract] [Full Text] [PDF]

Liliane A. Dickinson, John W. Trauger, Eldon E. Baird, Peter B. Dervan, Barbara J. Graves, and Joel M. Gottesfeld

Inhibition of Ets-1 DNA Binding and Ternary Complex Formation between Ets-1, NF-B, and DNA by a Designed DNA-binding Ligand
1999 274: 12765-12773. [Abstract] [Full Text] [PDF]

Sandra L. Grimm and Steven K. Nordeen

A Composite Enhancer Element Directing Tissue-specific Expression of Mouse Mammary Tumor Virus Requires both Ubiquitous and Tissue-restricted Factors
1999 274: 12790-12796. [Abstract] [Full Text] [PDF]

Michael Fry and Lawrence A. Loeb

Human Werner Syndrome DNA Helicase Unwinds Tetrahelical Structures of the Fragile X Syndrome Repeat Sequence d(CGG)_n
1999 274: 12797-12802. [Abstract] [Full Text] [PDF]

Guangmao Cheng, Tyson P. Hagen, Myra L. Dawson, Kimberly V. Barnes, and Donald R. Menick

The Role of GATA, CArG, E-box, and a Novel Element in the Regulation of Cardiac Expression of the Na⁺-Ca²⁺ Exchanger Gene
1999 274: 12819-12826. [Abstract] [Full Text] [PDF]

Sibylle G. Blumenthal, Gabriele Aichele, Thomas Wirth, Armin P. Czernilofsky, Alfred Nordheim, and Jürgen Dittmer

Regulation of the Human Interleukin-5 Promoter by Ets Transcription Factors. ETS1 AND ETS2, BUT NOT ELF-1, COOPERATE WITH GATA3 AND HTLV-I TAX₁
1999 274: 12910-12916. [Abstract] [Full Text] [PDF]

Claude Jourdan-Le Saux, Heike Tronecker, Ljubica Bogic, Gillian D. Bryant-Greenwood, Charles D. Boyd, and Katalin Csiszar

The LOXL2 Gene Encodes a New Lysyl Oxidase-like Protein and Is Expressed at High Levels in Reproductive Tissues
1999 274: 12939-12944. [Abstract] [Full Text] [PDF]

Protein Chemistry and Structure

Anne Waldow, Bernhard Schmidt, Thomas Dierks, Rixa von Bülow, and Kurt von Figura

Amino Acid Residues Forming the Active Site of Arylsulfatase A. ROLE IN CATALYTIC ACTIVITY AND SUBSTRATE BINDING
1999 274: 12284-12288. [Abstract] [Full Text] [PDF]

Ana Victoria Bendetowicz, Robert J. Wise, and Gary E. Gilbert

Collagen-bound von Willebrand Factor Has Reduced Affinity for Factor VIII
1999 274: 12300-12307. [Abstract] [Full Text] [PDF]

Ailsa G. Harpur, Meredith J. Layton, Pamela Das, Matthew J. Bottomley, George Panayotou, Paul C. Driscoll, and Michael D. Waterfield

Intermolecular Interactions of the p85 Regulatory Subunit of Phosphatidylinositol 3-Kinase
1999 274: 12323-12332. [Abstract] [Full Text] [PDF]

Vivian W-C Yang, Steven R. LaBrenz, Lawrence C. Rosenberg, David McQuillan, and Magnus Höök

Decorin Is a Zn²⁺ Metalloprotein
1999 274: 12454-12460. [Abstract] [Full Text] [PDF]

Cezary Marcinkiewicz, Juan J. Calvete, Mariola M. Marcinkiewicz, Manfred Raida, Senadhi Vijay-Kumar, Ziwei Huang, Roy R. Lobb, and Stefan Niewiarowski

EC3, a Novel Heterodimeric Disintegrin from Echis carinatus Venom, Inhibits 4 and 5 Integrins in an RGD-independent Manner
1999 274: 12468-12473. [Abstract] [Full Text] [PDF]

Christian Le Gouill, Jean-Luc Parent, Carolyn-Ann Caron, Rémi Gaudreau, Léonid Volkov, Marek Rola-Pleszczynski, and Jana Stanková

Selective Modulation of Wild Type Receptor Functions by Mutants of G-Protein-coupled Receptors
1999 274: 12548-12554. [Abstract] [Full Text] [PDF]

Richard Kao and Julian Davies

Molecular Dissection of Mitogillin Reveals That the Fungal Ribotoxins Are a Family of Natural Genetically Engineered Ribonucleases
1999 274: 12576-12582. [Abstract] [Full Text] [PDF]

Lars O. Tjernberg, David J. E. Callaway, Agneta Tjernberg, Solveig Hahne, Christina Lilliehöök, Lars Terenius, Johan Thyberg, and Christer Nordstedt

A Molecular Model of Alzheimer Amyloid -Peptide Fibril Formation
1999 274: 12619-12625. [Abstract] [Full Text] [PDF]

Ruoli Bai, John B. Ewell, Nga Y. Nguyen, and Ernest Hamel

Direct Photoaffinity Labeling of Cysteine 211 or a Nearby Amino Acid Residue of -Tubulin by Guanosine 5'-Diphosphate Bound in the Exchangeable Site
1999 274: 12710-12714. [Abstract] [Full Text] [PDF]

Michael P. Schwartz, Shihai Huang, and Andreas Matouschek

The Structure of Precursor Proteins during Import into Mitochondria
1999 274: 12759-12764. [Abstract] [Full Text] [PDF]

Hirofumi Ogawa, Fusao Takusagawa, Kunihiko Wakaki, Hiroyuki Kishi, Mohammad R. Eskandarian, Masashi Kobayashi, Takayasu Date, Num-Ho Huh, and Henry C. Pitot

Rat Liver Serine Dehydratase. BACTERIAL EXPRESSION AND TWO FOLDING DOMAINS AS REVEALED BY LIMITED PROTEOLYSIS
1999 274: 12855-12860. [Abstract] [Full Text] [PDF]

Tina M. Leisner, June D. Wencel-Drake, Wei Wang, and Stephen C.-T. Lam

Bidirectional Transmembrane Modulation of Integrin _IIb3 Conformations
1999 274: 12945-12949. [Abstract] [Full Text] [PDF]

Additions and Corrections

Matthew P. Hoffman, Motoyoshi Nomizu, Eva Roque, Sharon Lee, Dale W. Jung, Yoshi Yamada, and Hynda K. Kleinman

Additions and Corrections to Laminin-1 and laminin-2 G-domain synthetic peptides bind syndecan-1 and are involved in acinar formation of a human submandibular gland cell line.
1999 274: 12950. [Full Text] [PDF]

Roger A. Bascom, Sudha Srinivasan, and Robert L. Nussbaum

Additions and Corrections to Identification and characterization of golgin-84, a novel Golgi integral membrane protein with a cytoplasmic coiled-coil domain.
1999 274: 12950. [Full Text] [PDF]

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