Minireviews

Jackie D. Corbin and Sharron H. Francis

Cyclic GMP Phosphodiesterase-5: Target of Sildenafil
1999 274: 13729-13732. [Full Text] [PDF]

Communications

Kang-Yeol Yu, Byungsuk Kwon, Jian Ni, Yifan Zhai, Reinhard Ebner, and Byoung S. Kwon

A Newly Identified Member of Tumor Necrosis Factor Receptor Superfamily (TR6) Suppresses LIGHT-mediated Apoptosis
1999 274: 13733-13736. [Abstract] [Full Text] [PDF]

Craig Gatto, Svetlana Lutsenko, Jai Moo Shin, George Sachs, and Jack H. Kaplan

Stabilization of the H,K-ATPase M5M6 Membrane Hairpin by K⁺ Ions. MECHANISTIC SIGNIFICANCE FOR P₂-TYPE ATPases
1999 274: 13737-13740. [Abstract] [Full Text] [PDF]

Grigory L. Dianov, Rajendra Prasad, Samuel H. Wilson, and Vilhelm A. Bohr

Role of DNA Polymerase  in the Excision Step of Long Patch Mammalian Base Excision Repair
1999 274: 13741-13743. [Abstract] [Full Text] [PDF]

Jinmin Zhao, Keiko Furukawa, Satoshi Fukumoto, Masahiko Okada, Reiko Furugen, Hiroshi Miyazaki, Kogo Takamiya, Shinichi Aizawa, Hiroshi Shiku, Toshifumi Matsuyama, and Koichi Furukawa

Attenuation of Interleukin 2 Signal in the Spleen Cells of Complex Ganglioside-lacking Mice
1999 274: 13744-13747. [Abstract] [Full Text] [PDF]

Ludwig Missiaen, Jan B. Parys, A. Freek Weidema, Henk Sipma, Sara Vanlingen, Patrick De Smet, Geert Callewaert, and Humbert De Smedt

The Bell-shaped Ca²⁺ Dependence of the Inositol 1,4,5-Trisphosphate-induced Ca²⁺ Release Is Modulated by Ca²⁺/Calmodulin
1999 274: 13748-13751. [Abstract] [Full Text] [PDF]

Carbohydrates, Lipids, and Other Natural Products

Hiroshi Kitagawa, Hiromi Shimakawa, and Kazuyuki Sugahara

The Tumor Suppressor EXT-like Gene EXTL2 Encodes an 1, 4-N-Acetylhexosaminyltransferase That Transfers N-Acetylgalactosamine and N-Acetylglucosamine to the Common Glycosaminoglycan-Protein Linkage Region. THE KEY ENZYME FOR THE CHAIN INITIATION OF HEPARAN SULFATE
1999 274: 13933-13937. [Abstract] [Full Text] [PDF]

Dipika Gupta, Qiuling Wang, Charles Vinson, and Roman Dziarski

Bacterial Peptidoglycan Induces CD14-dependent Activation of Transcription Factors CREB/ATF and AP-1
1999 274: 14012-14020. [Abstract] [Full Text] [PDF]

Cell Biology and Metabolism

Zhiqiang Qu, Guoyun Zhu, Zhenjiang Yang, Ningren Cui, Yingjie Li, Sengthong Chanchevalap, Sharifa Sulaiman, Holland Haynie, and Chun Jiang

Identification of a Critical Motif Responsible for Gating of Kir2.3 Channel by Intracellular Protons
1999 274: 13783-13789. [Abstract] [Full Text] [PDF]

Mira Rosenblat, Paula Belinky, Jacob Vaya, Rachel Levy, Tony Hayek, Raymond Coleman, Shoshana Merchav, and Michael Aviram

Macrophage Enrichment with the Isoflavan Glabridin Inhibits NADPH Oxidase-induced Cell-mediated Oxidation of Low Density Lipoprotein. A POSSIBLE ROLE FOR PROTEIN KINASE C
1999 274: 13790-13799. [Abstract] [Full Text] [PDF]

Carlos A. Saura, Taisuke Tomita, Frances Davenport, Christie L. Harris, Takeshi Iwatsubo, and Gopal Thinakaran

Evidence That Intramolecular Associations between Presenilin Domains Are Obligatory for Endoproteolytic Processing
1999 274: 13818-13823. [Abstract] [Full Text] [PDF]

Xiquan Liang, Dai Zhu, and Horst Schulz

^3,5,7,^2,4,6-Trienoyl-CoA Isomerase, a Novel Enzyme That Functions in the -Oxidation of Polyunsaturated Fatty Acids with Conjugated Double Bonds
1999 274: 13830-13835. [Abstract] [Full Text] [PDF]

Xuesong Liu, Hua Zou, Piotr Widlak, William Garrard, and Xiaodong Wang

Activation of the Apoptotic Endonuclease DFF40 (Caspase-activated DNase or Nuclease). OLIGOMERIZATION AND DIRECT INTERACTION WITH HISTONE H1
1999 274: 13836-13840. [Abstract] [Full Text] [PDF]

Jacqueline L. Norris and Albert S. Baldwin Jr.

Oncogenic Ras Enhances NF-B Transcriptional Activity through Raf-dependent and Raf-independent Mitogen-activated Protein Kinase Signaling Pathways
1999 274: 13841-13846. [Abstract] [Full Text] [PDF]

Yong-Xiao Wang, Prasad D. K. Dhulipala, Lei Li, Jeffrey L. Benovic, and Michael I. Kotlikoff

Coupling of M₂ Muscarinic Receptors to Membrane Ion Channels via Phosphoinositide 3-Kinase  and Atypical Protein Kinase C
1999 274: 13859-13864. [Abstract] [Full Text] [PDF]

Richard Y. Liu, Chun Fan, Nancy E. Olashaw, Xue Wang, and Kenneth S. Zuckerman

Tumor Necrosis Factor--induced Proliferation of Human Mo7e Leukemic Cells Occurs via Activation of Nuclear Factor B Transcription Factor
1999 274: 13877-13885. [Abstract] [Full Text] [PDF]

Michiko Shirane, Yumiko Harumiya, Noriko Ishida, Aizan Hirai, Chikara Miyamoto, Shigetsugu Hatakeyama, Kei-ichi Nakayama, and Masatoshi Kitagawa

Down-regulation of p27^Kip1 by Two Mechanisms, Ubiquitin-mediated Degradation and Proteolytic Processing
1999 274: 13886-13893. [Abstract] [Full Text] [PDF]

Anna Hopf, Rainer Schreiber, Marcus Mall, Rainer Greger, and Karl Kunzelmann

Cystic Fibrosis Transmembrane Conductance Regulator Inhibits Epithelial Na⁺ Channels Carrying Liddle's Syndrome Mutations
1999 274: 13894-13899. [Abstract] [Full Text] [PDF]

Fujio Sekiya, Yun Soo Bae, Deok Young Jhon, Sung Chul Hwang, and Sue Goo Rhee

AHNAK, a Protein That Binds and Activates Phospholipase C-1 in the Presence of Arachidonic Acid
1999 274: 13900-13907. [Abstract] [Full Text] [PDF]

Taro Matsumoto, Koutaro Yokote, Ken Tamura, Minoru Takemoto, Hikaru Ueno, Yasushi Saito, and Seijiro Mori

Platelet-derived Growth Factor Activates p38 Mitogen-activated Protein Kinase through a Ras-dependent Pathway That Is Important for Actin Reorganization and Cell Migration
1999 274: 13954-13960. [Abstract] [Full Text] [PDF]

Brian G. Gabrielli, Boris Sarcevic, Joanne Sinnamon, Graeme Walker, Marina Castellano, Xue-Qing Wang, and Kay A. O. Ellem

A Cyclin D-Cdk4 Activity Required for G₂ Phase Cell Cycle Progression Is Inhibited in Ultraviolet Radiation-induced G₂ Phase Delay
1999 274: 13961-13969. [Abstract] [Full Text] [PDF]

Gregory J. Della Rocca, Stuart Maudsley, Yehia Daaka, Robert J. Lefkowitz, and Louis M. Luttrell

Pleiotropic Coupling of G Protein-coupled Receptors to the Mitogen-activated Protein Kinase Cascade. ROLE OF FOCAL ADHESIONS AND RECEPTOR TYROSINE KINASES
1999 274: 13978-13984. [Abstract] [Full Text] [PDF]

Victor I. Shifrin and Paul Anderson

Trichothecene Mycotoxins Trigger a Ribotoxic Stress Response That Activates c-Jun N-terminal Kinase and p38 Mitogen-activated Protein Kinase and Induces Apoptosis
1999 274: 13985-13992. [Abstract] [Full Text] [PDF]

Robin R. Ingalls, Brian G. Monks, and Douglas T. Golenbock

Membrane Expression of Soluble Endotoxin-binding Proteins Permits Lipopolysaccharide Signaling in Chinese Hamster Ovary Fibroblasts Independently of CD14
1999 274: 13993-13998. [Abstract] [Full Text] [PDF]

Noomen Ben El Hadj, Michel R. Popoff, Jean-Christophe Marvaud, Bernard Payrastre, Patrice Boquet, and Blandine Geny

G-protein-stimulated Phospholipase D Activity Is Inhibited by Lethal Toxin from Clostridium sordellii in HL-60 Cells
1999 274: 14021-14031. [Abstract] [Full Text] [PDF]

Oleg Varlamov, Fang Wu, Dennis Shields, and Lloyd D. Fricker

Biosynthesis and Packaging of Carboxypeptidase D into Nascent Secretory Vesicles in Pituitary Cell Lines
1999 274: 14040-14045. [Abstract] [Full Text] [PDF]

Klas Blomgren, Ulrika Hallin, Anna-Lena Andersson, Malgorzata Puka-Sundvall, Ben A. Bahr, Amanda McRae, Takaomi C. Saido, Seiichi Kawashima, and Henrik Hagberg

Calpastatin Is Up-regulated in Response to Hypoxia and Is a Suicide Substrate to Calpain after Neonatal Cerebral Hypoxia-Ischemia
1999 274: 14046-14052. [Abstract] [Full Text] [PDF]

Galini Thoidis, Tatyana Kupriyanova, Jeffrey M. Cunningham, Peng Chen, Sandrine Cadel, Thierry Foulon, Paul Cohen, Richard E. Fine, and Konstantin V. Kandror

Glucose Transporter Glut3 Is Targeted to Secretory Vesicles in Neurons and PC12 Cells
1999 274: 14062-14066. [Abstract] [Full Text] [PDF]

Ann J. Barbier, Helen M. Poppleton, Yinges Yigzaw, Jason B. Mullenix, Gregory J. Wiepz, Paul J. Bertics, and Tarun B. Patel

Transmodulation of Epidermal Growth Factor Receptor Function by Cyclic AMP-dependent Protein Kinase
1999 274: 14067-14073. [Abstract] [Full Text] [PDF]

M. L. Standaert, G. Bandyopadhyay, M. P. Sajan, L. Cong, M. J. Quon, and R. V. Farese

Okadaic Acid Activates Atypical Protein Kinase C (/) in Rat and 3T3/L1 Adipocytes. AN APPARENT REQUIREMENT FOR ACTIVATION OF GLUT4 TRANSLOCATION AND GLUCOSE TRANSPORT
1999 274: 14074-14078. [Abstract] [Full Text] [PDF]

Vladimir N. Ivanov and Ze'ev Ronai

Down-regulation of Tumor Necrosis Factor  Expression by Activating Transcription Factor 2 Increases UVC-induced Apoptosis of Late-stage Melanoma Cells
1999 274: 14079-14089. [Abstract] [Full Text] [PDF]

Chie Sakanaka and Lewis T. Williams

Functional Domains of Axin. IMPORTANCE OF THE C TERMINUS AS AN OLIGOMERIZATION DOMAIN
1999 274: 14090-14093. [Abstract] [Full Text] [PDF]

Jean-Christophe Jonas, Arun Sharma, Wendy Hasenkamp, Hasan Ilkova, Giovanni Patanè, Ross Laybutt, Susan Bonner-Weir, and Gordon C. Weir

Chronic Hyperglycemia Triggers Loss of Pancreatic  Cell Differentiation in an Animal Model of Diabetes
1999 274: 14112-14121. [Abstract] [Full Text] [PDF]

Hassan Mziaut, George Korza, Arthur R. Hand, Craig Gerard, and Juris Ozols

Targeting Proteins to the Lumen of Endoplasmic Reticulum Using N-terminal Domains of 11-Hydroxysteroid Dehydrogenase and the 50-kDa Esterase
1999 274: 14122-14129. [Abstract] [Full Text] [PDF]

Li-Hsien Wang, Robert G. Kalb, and Stephen M. Strittmatter

A PDZ Protein Regulates the Distribution of the Transmembrane Semaphorin, M-SemF
1999 274: 14137-14146. [Abstract] [Full Text] [PDF]

George G. Holz, Colin A. Leech, R. Scott Heller, Maurice Castonguay, and Joel F. Habener

cAMP-dependent Mobilization of Intracellular Ca²⁺ Stores by Activation of Ryanodine Receptors in Pancreatic -Cells. A Ca²⁺ SIGNALING SYSTEM STIMULATED BY THE INSULINOTROPIC HORMONE GLUCAGON-LIKE PEPTIDE-1-(7-37)
1999 274: 14147-14156. [Abstract] [Full Text] [PDF]

György Hajnóczky, Richard Hager, and Andrew P. Thomas

Mitochondria Suppress Local Feedback Activation of Inositol 1,4,5-Trisphosphate Receptors by Ca²⁺
1999 274: 14157-14162. [Abstract] [Full Text] [PDF]

Isabella Parolini, Stefania Topa, Maurizio Sorice, Alberto Pace, Piergiuseppe Ceddia, Elisabetta Montesoro, Antonio Pavan, Michael P. Lisanti, Cesare Peschle, and Massimo Sargiacomo

Phorbol Ester-induced Disruption of the CD4-Lck Complex Occurs within a Detergent-resistant Microdomain of the Plasma Membrane. INVOLVEMENT OF THE TRANSLOCATION OF ACTIVATED PROTEIN KINASE C ISOFORMS
1999 274: 14176-14187. [Abstract] [Full Text] [PDF]

Liyun Zhao, J. Bernd Helms, Josef Brunner, and Felix T. Wieland

GTP-dependent Binding of ADP-ribosylation Factor to Coatomer in Close Proximity to the Binding Site for Dilysine Retrieval Motifs and p23
1999 274: 14198-14203. [Abstract] [Full Text] [PDF]

Sylvain Le Bonniec, Christiane Deregnaucourt, Virginie Redeker, Ritu Banerjee, Philippe Grellier, Daniel E. Goldberg, and Joseph Schrével

Plasmepsin II, an Acidic Hemoglobinase from the Plasmodium falciparum Food Vacuole, Is Active at Neutral pH on the Host Erythrocyte Membrane Skeleton
1999 274: 14218-14223. [Abstract] [Full Text] [PDF]

Michele Pelosi, Vincenzo Di Bartolo, Virginie Mounier, Dominique Mège, Jean-Marc Pascussi, Evelyne Dufour, Arnaud Blondel, and Oreste Acuto

Tyrosine 319 in the Interdomain B of ZAP-70 Is a Binding Site for the Src Homology 2 Domain of Lck
1999 274: 14229-14237. [Abstract] [Full Text] [PDF]

Steven S. Pullen, Thu T. A. Dang, James J. Crute, and Marilyn R. Kehry

CD40 Signaling through Tumor Necrosis Factor Receptor-associated Factors (TRAFs). BINDING SITE SPECIFICITY AND ACTIVATION OF DOWNSTREAM PATHWAYS BY DISTINCT TRAFs
1999 274: 14246-14254. [Abstract] [Full Text] [PDF]

Jeanine G. R. Boesen-de Cock, Annemiek D. Tepper, Evert de Vries, Wim J. van Blitterswijk, and Jannie Borst

Common Regulation of Apoptosis Signaling Induced by CD95 and the DNA-damaging Stimuli Etoposide and -Radiation Downstream from Caspase-8 Activation
1999 274: 14255-14261. [Abstract] [Full Text] [PDF]

Chi-Ying F. Huang, Chao-Pei Betty Chang, Chia-Lin Huang, and James E. Ferrell Jr.

M Phase Phosphorylation of Cytoplasmic Dynein Intermediate Chain and p150^Glued
1999 274: 14262-14269. [Abstract] [Full Text] [PDF]

Yael Webb, Xianbo Zhou, Lang Ngo, Virginia Cornish, Joachim Stahl, Hediye Erdjument-Bromage, Paul Tempst, Richard A. Rifkind, Paul A. Marks, Ronald Breslow, and Victoria M. Richon

Photoaffinity Labeling and Mass Spectrometry Identify Ribosomal Protein S3 as a Potential Target for Hybrid Polar Cytodifferentiation Agents
1999 274: 14280-14287. [Abstract] [Full Text] [PDF]

Katsuya Egawa, Prem M. Sharma, Naoki Nakashima, Yi Huang, Evana Huver, Gerry R. Boss, and Jerrold M. Olefsky

Membrane-targeted Phosphatidylinositol 3-Kinase Mimics Insulin Actions and Induces a State of Cellular Insulin Resistance
1999 274: 14306-14314. [Abstract] [Full Text] [PDF]

Wayne B. Bowler, Catherine J. Dixon, Christine Halleux, Rainer Maier, Graeme Bilbe, William D. Fraser, James A. Gallagher, and Robert A. Hipskind

Signaling in Human Osteoblasts by Extracellular Nucleotides. THEIR WEAK INDUCTION OF THE c-fos PROTO-ONCOGENE VIA Ca²⁺ MOBILIZATION IS STRONGLY POTENTIATED BY A PARATHYROID HORMONE/cAMP-DEPENDENT PROTEIN KINASE PATHWAY INDEPENDENTLY OF MITOGEN-ACTIVATED PROTEIN KINASE
1999 274: 14315-14324. [Abstract] [Full Text] [PDF]

Yasmine Djellas, Jeanne M. Manganello, Kostas Antonakis, and Guy C. Le Breton

Identification of G₁₃ as One of the G-proteins That Couple to Human Platelet Thromboxane A₂ Receptors
1999 274: 14325-14330. [Abstract] [Full Text] [PDF]

Simone M. Schoenwaelder and Keith Burridge

Evidence for a Calpeptin-sensitive Protein-tyrosine Phosphatase Upstream of the Small GTPase Rho. A NOVEL ROLE FOR THE CALPAIN INHIBITOR CALPEPTIN IN THE INHIBITION OF PROTEIN-TYROSINE PHOSPHATASES
1999 274: 14359-14367. [Abstract] [Full Text] [PDF]

Alessio Pigazzi, Stanley Heydrick, Franco Folli, Stephen Benoit, Alan Michelson, and Joseph Loscalzo

Nitric Oxide Inhibits Thrombin Receptor-activating Peptide-induced Phosphoinositide 3-Kinase Activity in Human Platelets
1999 274: 14368-14375. [Abstract] [Full Text] [PDF]

Tamotsu Ichiba, Yuko Hashimoto, Mie Nakaya, Yasunobu Kuraishi, Shinya Tanaka, Takeshi Kurata, Naoki Mochizuki, and Michiyuki Matsuda

Activation of C3G Guanine Nucleotide Exchange Factor for Rap1 by Phosphorylation of Tyrosine 504
1999 274: 14376-14381. [Abstract] [Full Text] [PDF]

Egon Ogris, Xianxing Du, Kasey C. Nelson, Elsa K. Mak, Xing Xian Yu, William S. Lane, and David C. Pallas

A Protein Phosphatase Methylesterase (PME-1) Is One of Several Novel Proteins Stably Associating with Two Inactive Mutants of Protein Phosphatase 2A
1999 274: 14382-14391. [Abstract] [Full Text] [PDF]

André Veillette, David Soussou, Sylvain Latour, Dominique Davidson, and François G. Gervais

Interactions of CD45-associated Protein with the Antigen Receptor Signaling Machinery in T-lymphocytes
1999 274: 14392-14399. [Abstract] [Full Text] [PDF]

Christina Olsson, Kristian Riebeck, Mikael Dohlsten, and Erik Michaëlsson

CTLA-4 Ligation Suppresses CD28-induced NF-B and AP-1 Activity in Mouse T Cell Blasts
1999 274: 14400-14405. [Abstract] [Full Text] [PDF]

Greg Vilk, Ronald B. Saulnier, Rebecca St. Pierre, and David W. Litchfield

Inducible Expression of Protein Kinase CK2 in Mammalian Cells. EVIDENCE FOR FUNCTIONAL SPECIALIZATION OF CK2 ISOFORMS
1999 274: 14406-14414. [Abstract] [Full Text] [PDF]

Deborah G. Murdock, Braden E. Boone, Luke A. Esposito, and Douglas C. Wallace

Up-regulation of Nuclear and Mitochondrial Genes in the Skeletal Muscle of Mice Lacking the Heart/Muscle Isoform of the Adenine Nucleotide Translocator
1999 274: 14429-14433. [Abstract] [Full Text] [PDF]

Olaf Heidenreich, Armin Neininger, Gerhard Schratt, Raymund Zinck, Michael A. Cahill, Katrin Engel, Alexey Kotlyarov, Regine Kraft, Susanne Kostka, Matthias Gaestel, and Alfred Nordheim

MAPKAP Kinase 2 Phosphorylates Serum Response Factor in Vitro and in Vivo
1999 274: 14434-14443. [Abstract] [Full Text] [PDF]

Jian Hua Qi, Nobuyuki Ito, and Lena Claesson-Welsh

Tyrosine Phosphatase SHP-2 Is Involved in Regulation of Platelet-derived Growth Factor-induced Migration
1999 274: 14455-14463. [Abstract] [Full Text] [PDF]

María A. Diversé-Pierluissi, Thierry Fischer, J. Dedrick Jordan, Max Schiff, Daniel F. Ortiz, Marilyn G. Farquhar, and Luc De Vries

Regulators of G Protein Signaling Proteins as Determinants of the Rate of Desensitization of Presynaptic Calcium Channels
1999 274: 14490-14494. [Abstract] [Full Text] [PDF]

Lucas Pelkmans and Ari Helenius

Expression of Antibody Interferes with Disulfide Bond Formation and Intracellular Transport of Antigen in the Secretory Pathway
1999 274: 14495-14499. [Abstract] [Full Text] [PDF]

Rupert Grossberger, Christian Gieffers, Wolfgang Zachariae, Alexandre V. Podtelejnikov, Alexander Schleiffer, Kim Nasmyth, Matthias Mann, and Jan-Michael Peters

Characterization of the DOC1/APC10 Subunit of the Yeast and the Human Anaphase-promoting Complex
1999 274: 14500-14507. [Abstract] [Full Text] [PDF]

Enzymology

Sophie Réhault, Michèle Brillard-Bourdet, Maria A. Juliano, Luiz Juliano, Francis Gauthier, and Thierry Moreau

New, Sensitive Fluorogenic Substrates for Human Cathepsin G Based on the Sequence of Serpin-reactive Site Loops
1999 274: 13810-13817. [Abstract] [Full Text] [PDF]

Henry N. Kirkman, Michela Rolfo, Anna M. Ferraris, and Gian F. Gaetani

Mechanisms of Protection of Catalase by NADPH. KINETICS AND STOICHIOMETRY
1999 274: 13908-13914. [Abstract] [Full Text] [PDF]

Monique Beullens, Aleyde Van Eynde, Veerle Vulsteke, John Connor, Shirish Shenolikar, Willy Stalmans, and Mathieu Bollen

Molecular Determinants of Nuclear Protein Phosphatase-1 Regulation by NIPP-1
1999 274: 14053-14061. [Abstract] [Full Text] [PDF]

Membranes and Bioenergetics

Maxim Sokolov, Lu Lu, Ward Tucker, Fei Gao, Peter A. Gegenheimer, and Mark L. Richter

The 20 C-terminal Amino Acid Residues of the Chloroplast ATP Synthase  Subunit Are Not Essential for Activity
1999 274: 13824-13829. [Abstract] [Full Text] [PDF]

Tongqing Zhou and Barry P. Rosen

Asp⁴⁵ Is a Mg²⁺ Ligand in the ArsA ATPase
1999 274: 13854-13858. [Abstract] [Full Text] [PDF]

Sasanka Ramanadham, Fong-Fu Hsu, Alan Bohrer, Zhongmin Ma, and John Turk

Studies of the Role of Group VI Phospholipase A₂ in Fatty Acid Incorporation, Phospholipid Remodeling, Lysophosphatidylcholine Generation, and Secretagogue-induced Arachidonic Acid Release in Pancreatic Islets and Insulinoma Cells
1999 274: 13915-13927. [Abstract] [Full Text] [PDF]

Yong-Geun Kwak, NingNing Hu, Jian Wei, Alfred L. George Jr., Tammy D. Grobaski, Michael M. Tamkun, and Katherine T. Murray

Protein Kinase A Phosphorylation Alters Kv1.3 Subunit-mediated Inactivation of the Kv1.5 Potassium Channel
1999 274: 13928-13932. [Abstract] [Full Text] [PDF]

Hyangee Oh, Yongkyu Park, and Chankyu Park

A Mutated PtsG, the Glucose Transporter, Allows Uptake of D-Ribose
1999 274: 14006-14011. [Abstract] [Full Text] [PDF]

Nucleic Acids, Protein Synthesis, and Molecular Genetics

Raj Wadgaonkar and Tucker Collins

Murine Double Minute (MDM2) Blocks p53-coactivator Interaction, a New Mechanism for Inhibition of p53-dependent Gene Expression
1999 274: 13760-13767. [Abstract] [Full Text] [PDF]

Balazs Gereben, Tibor Bartha, Helen M. Tu, John W. Harney, Peter Rudas, and P. Reed Larsen

Cloning and Expression of the Chicken Type 2 Iodothyronine 5'-Deiodinase
1999 274: 13768-13776. [Abstract] [Full Text] [PDF]

Iñigo Santamaría, Gloria Velasco, Alberto M. Pendás, Ana Paz, and Carlos López-Otín

Molecular Cloning and Structural and Functional Characterization of Human Cathepsin F, a New Cysteine Proteinase of the Papain Family with a Long Propeptide Domain
1999 274: 13800-13809. [Abstract] [Full Text] [PDF]

Chi-Jiunn Pan, Baochuan Lin, and Janice Yang Chou

Transmembrane Topology of Human Glucose 6-Phosphate Transporter
1999 274: 13865-13869. [Abstract] [Full Text] [PDF]

Christoph Dorn, Qinglin Ou, John Svaren, Peter A. Crawford, and Yoel Sadovsky

Activation of Luteinizing Hormone  Gene by Gonadotropin-releasing Hormone Requires the Synergy of Early Growth Response-1 and Steroidogenic Factor-1
1999 274: 13870-13876. [Abstract] [Full Text] [PDF]

Giovanni Perini, Elke Oetjen, and Michael R. Green

The Hepatitis B pX Protein Promotes Dimerization and DNA Binding of Cellular Basic Region/Leucine Zipper Proteins by Targeting the Conserved Basic Region
1999 274: 13970-13977. [Abstract] [Full Text] [PDF]

Mark Odell and Stewart Shuman

Footprinting of Chlorella Virus DNA Ligase Bound at a Nick in Duplex DNA
1999 274: 14032-14039. [Abstract] [Full Text] [PDF]

Antti Iivanainen, Takako Morita, and Karl Tryggvason

Molecular Cloning and Tissue-specific Expression of a Novel Murine Laminin 3 Chain
1999 274: 14107-14111. [Abstract] [Full Text] [PDF]

Ken-ichi Hirata, Helén L. Dichek, Joseph A. Cioffi, Sungshin Y. Choi, Nicholas J. Leeper, Leah Quintana, Gregory S. Kronmal, Allen D. Cooper, and Thomas Quertermous

Cloning of a Unique Lipase from Endothelial Cells Extends the Lipase Gene Family
1999 274: 14170-14175. [Abstract] [Full Text] [PDF]

Amy L. Lewis, Yang Xia, Surjit K. Datta, Jeanie McMillin, and Rodney E. Kellems

Combinatorial Interactions Regulate Cardiac Expression of the Murine Adenylosuccinate Synthetase 1 Gene
1999 274: 14188-14197. [Abstract] [Full Text] [PDF]

Scott A. Rivkees, Marisa Chen, Jayant Kulkarni, Jeffrey Browne, and Zhiyong Zhao

Characterization of the Murine A1 Adenosine Receptor Promoter, Potent Regulation by GATA-4 and Nkx2.5
1999 274: 14204-14209. [Abstract] [Full Text] [PDF]

Hyung-Suk Kim, Nobuyo Maeda, Goo Taeg Oh, Lucas G. Fernandez, R. Ariel Gomez, and Oliver Smithies

Homeostasis in Mice with Genetically Decreased Angiotensinogen Is Primarily by an Increased Number of Renin-producing Cells
1999 274: 14210-14217. [Abstract] [Full Text] [PDF]

Mary Hanlon and Linda Sealy

Ras Regulates the Association of Serum Response Factor and CCAAT/Enhancer-binding Protein
1999 274: 14224-14228. [Abstract] [Full Text] [PDF]

Robert J. Kelm Jr., John G. Cogan, Paula K. Elder, Arthur R. Strauch, and Michael J. Getz

Molecular Interactions between Single-stranded DNA-binding Proteins Associated with an Essential MCAT Element in the Mouse Smooth Muscle -Actin Promoter
1999 274: 14238-14245. [Abstract] [Full Text] [PDF]

John J. McCarthy, Dharmesh R. Vyas, Gretchen L. Tsika, and Richard W. Tsika

Segregated Regulatory Elements Direct -Myosin Heavy Chain Expression in Response to Altered Muscle Activity
1999 274: 14270-14279. [Abstract] [Full Text] [PDF]

Gloria Berrocal-Tito, Liat Sametz-Baron, Klaus Eichenberg, Benjamin A. Horwitz, and Alfredo Herrera-Estrella

Rapid Blue Light Regulation of a Trichoderma harzianum Photolyase Gene
1999 274: 14288-14294. [Abstract] [Full Text] [PDF]

Anna M. Krichevsky, Esther Metzer, and Haim Rosen

Translational Control of Specific Genes during Differentiation of HL-60 Cells
1999 274: 14295-14305. [Abstract] [Full Text] [PDF]

Dorina Avram, Jane E. Ishmael, Daniel J. Nevrivy, Valerie J. Peterson, Suk-Hyung Lee, Paul Dowell, and Mark Leid

Heterodimeric Interactions between Chicken Ovalbumin Upstream Promoter-Transcription Factor Family Members ARP1 and Ear2
1999 274: 14331-14336. [Abstract] [Full Text] [PDF]

Nicola A. Hawkes and Stefan G. E. Roberts

The Role of Human TFIIB in Transcription Start Site Selection in Vitro and in Vivo
1999 274: 14337-14343. [Abstract] [Full Text] [PDF]

Chung-Ming Hsieh, Shaw-Fang Yet, Matthew D. Layne, Masafumi Watanabe, Audrey M. Hong, Mark A. Perrella, and Mu-En Lee

Genomic Cloning and Promoter Analysis of Aortic Preferentially Expressed Gene-1. IDENTIFICATION OF A VASCULAR SMOOTH MUSCLE-SPECIFIC PROMOTER MEDIATED BY AN E BOX MOTIF
1999 274: 14344-14351. [Abstract] [Full Text] [PDF]

Dennis M. Kraichely, John J. Collins III, Robert K. DeLisle, and Paul N. MacDonald

The Autonomous Transactivation Domain in Helix H3 of the Vitamin D Receptor Is Required For Transactivation and Coactivator Interaction
1999 274: 14352-14358. [Abstract] [Full Text] [PDF]

Yin Hew, Zbyszko Grzelczak, Connie Lau, and Fred W. Keeley

Identification of a Large Region of Secondary Structure in the 3'-Untranslated Region of Chicken Elastin mRNA with Implications for the Regulation of mRNA Stability
1999 274: 14415-14421. [Abstract] [Full Text] [PDF]

Petr Kaspar, Marta Dvoráková, Jarmila Králová, Petr Pajer, Zbynek Kozmik, and Michal Dvorák

Myb-interacting Protein, ATBF1, Represses Transcriptional Activity of Myb Oncoprotein
1999 274: 14422-14428. [Abstract] [Full Text] [PDF]

Jeanette M. Quinn, Stacie S. Nakamoto, and Sabeeha Merchant

Induction of Coproporphyrinogen Oxidase in Chlamydomonas Chloroplasts Occurs via Transcriptional Regulation of Cpx1 Mediated by Copper Response Elements and Increased Translation from a Copper Deficiency-specific Form of the Transcript
1999 274: 14444-14454. [Abstract] [Full Text] [PDF]

Itai Bab, Elisheva Smith, Hanna Gavish, Malka Attar-Namdar, Michael Chorev, Yu-Chen Chen, Andrash Muhlrad, Mark J. Birnbaum, Gary Stein, and Baruch Frenkel

Biosynthesis of Osteogenic Growth Peptide via Alternative Translational Initiation at AUG₈₅ of Histone H4 mRNA
1999 274: 14474-14481. [Abstract] [Full Text] [PDF]

Johan Ericsson, Anny Usheva, and Peter A. Edwards

YY1 Is a Negative Regulator of Transcription of Three Sterol Regulatory Element-binding Protein-responsive Genes
1999 274: 14508-14513. [Abstract] [Full Text] [PDF]

Protein Chemistry and Structure

A. Grey Craig, Thomas Norberg, David Griffin, Carl Hoeger, Mateen Akhtar, Karsten Schmidt, William Low, John Dykert, Elliott Richelson, Valérie Navarro, Jean Mazella, Maren Watkins, David Hillyard, Julita Imperial, Lourdes J. Cruz, and Baldomero M. Olivera

Contulakin-G, an O-Glycosylated Invertebrate Neurotensin
1999 274: 13752-13759. [Abstract] [Full Text] [PDF]

Rhoda Elison Hirsch, Laura J. Juszczak, Nazim A. Fataliev, Joel M. Friedman, and Ronald L. Nagel

Solution-active Structural Alterations in Liganded Hemoglobins C (6 Glu  Lys) and S (6 Glu  Val)
1999 274: 13777-13782. [Abstract] [Full Text] [PDF]

Maria Jesus Arrizubieta and Everett Bandman

Regulation of -Helical Coiled-coil Dimerization in Chicken Skeletal Muscle Light Meromyosin
1999 274: 13847-13853. [Abstract] [Full Text] [PDF]

Richard J. Trevino, Francesca Gliubich, Rodolfo Berni, Michele Cianci, John M. Chirgwin, Giuseppe Zanotti, and Paul M. Horowitz

NH₂-terminal Sequence Truncation Decreases the Stability of Bovine Rhodanese, Minimally Perturbs Its Crystal Structure, and Enhances Interaction with GroEL under Native Conditions
1999 274: 13938-13947. [Abstract] [Full Text] [PDF]

Sung-Woo Cho and Hye-Young Yoon

Photoaffinity Labeling of Brain Glutamate Dehydrogenase Isoproteins with an Azido-ADP
1999 274: 13948-13953. [Abstract] [Full Text] [PDF]

Malgorzata Gonciarz-Swiatek, Alicja Wawrzynow, Soo-Jong Um, Brian A. Learn, Roger McMacken, William L. Kelley, Costa Georgopoulos, Olaf Sliekers, and Maciej Zylicz

Recognition, Targeting, and Hydrolysis of the  O Replication Protein by the ClpP/ClpX Protease
1999 274: 13999-14005. [Abstract] [Full Text] [PDF]

Terrence G. Gardner and Kelly P. Kearse

Modification of the T Cell Antigen Receptor (TCR) Complex by UDP-glucose:Glycoprotein Glucosyltransferase. TCR FOLDING IS FINALIZED CONVERGENT WITH FORMATION OF COMPLEXES
1999 274: 14094-14099. [Abstract] [Full Text] [PDF]

Ying-kui Yang, Chris J. Dickinson, Qun Zeng, Ji-Yao Li, Darren A. Thompson, and Ira Gantz

Contribution of Melanocortin Receptor Exoloops to Agouti-related Protein Binding
1999 274: 14100-14106. [Abstract] [Full Text] [PDF]

Wen Huang, Klavs Dolmer, and Peter G. W. Gettins

NMR Solution Structure of Complement-like Repeat CR8 from the Low Density Lipoprotein Receptor-related Protein
1999 274: 14130-14136. [Abstract] [Full Text] [PDF]

Steven A. Middleton, Francis P. Barbone, Dana L. Johnson, Robin L. Thurmond, Yun You, Frank J. McMahon, Renzhe Jin, Oded Livnah, Jennifer Tullai, Francis X. Farrell, Mark A. Goldsmith, Ian A. Wilson, and Linda K. Jolliffe

Shared and Unique Determinants of the Erythropoietin (EPO) Receptor Are Important for Binding EPO and EPO Mimetic Peptide
1999 274: 14163-14169. [Abstract] [Full Text] [PDF]

Douglas A. Plager, David A. Loegering, Deborah A. Weiler, James L. Checkel, Jill M. Wagner, Nigel J. Clarke, Stephen Naylor, Scott M. Page, Larry L. Thomas, Ingrid Akerblom, Ben Cocks, Susan Stuart, and Gerald J. Gleich

A Novel and Highly Divergent Homolog of Human Eosinophil Granule Major Basic Protein
1999 274: 14464-14473. [Abstract] [Full Text] [PDF]

Jean-Luc Taupin, Véronique Miossec, Vincent Pitard, Frédéric Blanchard, Sophie Daburon, Sylvie Raher, Yannick Jacques, Anne Godard, and Jean-François Moreau

Binding of Leukemia Inhibitory Factor (LIF) to Mutants of Its Low Affinity Receptor, gp190, Reveals a LIF Binding Site Outside and Interactions between the Two Cytokine Binding Domains
1999 274: 14482-14489. [Abstract] [Full Text] [PDF]

Additions and Corrections

Leonid Dzantiev and Louis J. Romano

Additions and Corrections to Interaction of Escherichia coli DNA polymerase I (Klenow fragment) with primer-templates containing N-acetyl-2-aminofluorene or N-2-aminofluorene adducts in the active site.
1999 274: 14514. [Full Text] [PDF]

Eying Chen, Radmila Hrdlickova, Jiri Nehyba, Dan L. Longo, Henry R. Bose Jr., and Chou-Chi H. Li

Additions and Corrections to Degradation of proto-oncoprotein c-Rel by the ubiquitin-proteasome pathway.
1999 274: 14514. [Full Text] [PDF]

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