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Table of Contents: Dec 10 1999; 274 (50) [Index by Author] Other Issues:

Minireviews
Communications
Carbohydrates, Lipids, and Other Natural Products
Cell Biology and Metabolism
Enzymology
Membranes and Bioenergetics
Nucleic Acids, Protein Synthesis, and Molecular Genetics
Protein Chemistry and Structure
Additions and Corrections
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Minireviews

Kostas Tokatlidis and Gottfried Schatz
Biogenesis of Mitochondrial Inner Membrane Proteins
1999 274: 35285-35288. [Full Text] [PDF]


Communications

Ralf Brundiers, Arnon Lavie, Thomas Veit, Jochen Reinstein, Ilme Schlichting, Nils Ostermann, Roger S. Goody, and Manfred Konrad
Modifying Human Thymidylate Kinase to Potentiate Azidothymidine Activation
1999 274: 35289-35292. [Abstract] [Full Text] [PDF]

Masatoshi Yamasaki, Noriyo Hashiguchi, Chiharu Fujiwara, Tsuneo Imanaka, Toshiro Tsukamoto, and Takashi Osumi
Formation of Peroxisomes from Peroxisomal Ghosts in a Peroxisome-deficient Mammalian Cell Mutant upon Complementation by Protein Microinjection
1999 274: 35293-35296. [Abstract] [Full Text] [PDF]

Michael Naumann, Dawadschargal Bech-Otschir, Xiaohua Huang, Katherine Ferrell, and Wolfgang Dubiel
COP9 Signalosome-directed c-Jun Activation/Stabilization Is Independent of JNK
1999 274: 35297-35300. [Abstract] [Full Text] [PDF]

Onno Kranenburg, Ingrid Verlaan, and Wouter H. Moolenaar
Dynamin Is Required for the Activation of Mitogen-activated Protein (MAP) Kinase by MAP Kinase Kinase
1999 274: 35301-35304. [Abstract] [Full Text] [PDF]

Inaki Azpiazu, Humberto Cruzblanca, Ping Li, Maurine Linder, Min Zhuo, and N. Gautam
A G Protein gamma  Subunit-specific Peptide Inhibits Muscarinic Receptor Signaling
1999 274: 35305-35308. [Abstract] [Full Text] [PDF]

Pavel Shiyanov, Alo Nag, and Pradip Raychaudhuri
Cullin 4A Associates with the UV-damaged DNA-binding Protein DDB
1999 274: 35309-35312. [Abstract] [Full Text] [PDF]


Carbohydrates, Lipids, and Other Natural Products

Kim Stieglitz, Barbara Seaton, and Mary F. Roberts
The Role of Interfacial Binding in the Activation of Streptomyces chromofuscus Phospholipase D by Phosphatidic Acid
1999 274: 35367-35374. [Abstract] [Full Text] [PDF]

Arjen R Mensenkamp, Miek C Jong, Harry van Goor, Marja J. A. van Luyn, Vincent Bloks, Rick Havinga, Peter J. Voshol, Marten H. Hofker, Ko Willems van Dijk, Louis M. Havekes, and Folkert Kuipers
Apolipoprotein E Participates in the Regulation of Very Low Density Lipoprotein-Triglyceride Secretion by the Liver
1999 274: 35711-35718. [Abstract] [Full Text] [PDF]

Hitoshi Shimano, Naoya Yahagi, Michiyo Amemiya-Kudo, Alyssa H. Hasty, Jun-ichi Osuga, Yoshiaki Tamura, Futoshi Shionoiri, Yoko Iizuka, Ken Ohashi, Kenji Harada, Takanari Gotoda, Shun Ishibashi, and Nobuhiro Yamada
Sterol Regulatory Element-binding Protein-1 as a Key Transcription Factor for Nutritional Induction of Lipogenic Enzyme Genes
1999 274: 35832-35839. [Abstract] [Full Text] [PDF]

Naoya Yahagi, Hitoshi Shimano, Alyssa H. Hasty, Michiyo Amemiya-Kudo, Hiroaki Okazaki, Yoshiaki Tamura, Yoko Iizuka, Futoshi Shionoiri, Ken Ohashi, Jun-ichi Osuga, Kenji Harada, Takanari Gotoda, Ryozo Nagai, Shun Ishibashi, and Nobuhiro Yamada
A Crucial Role of Sterol Regulatory Element-binding Protein-1 in the Regulation of Lipogenic Gene Expression by Polyunsaturated Fatty Acids
1999 274: 35840-35844. [Abstract] [Full Text] [PDF]


Cell Biology and Metabolism

Hong-Tao Ma, Cécile J. Favre, Randen L. Patterson, Michele R. Stone, and Donald L. Gill
Ca2+ Entry Activated by S-Nitrosylation. RELATIONSHIP TO STORE-OPERATED Ca2+ ENTRY
1999 274: 35318-35324. [Abstract] [Full Text] [PDF]

Helen W. Davey, Soo-Hee Park, David R. Grattan, Michael J. McLachlan, and David J. Waxman
STAT5b-deficient Mice Are Growth Hormone Pulse-resistant. ROLE OF STAT5b IN SEX-SPECIFIC LIVER P450 EXPRESSION
1999 274: 35331-35336. [Abstract] [Full Text] [PDF]

Fang Wang, James R. Van Brocklyn, John P. Hobson, Sharareh Movafagh, Zofia Zukowska-Grojec, Sheldon Milstien, and Sarah Spiegel
Sphingosine 1-Phosphate Stimulates Cell Migration through a Gi-coupled Cell Surface Receptor. POTENTIAL INVOLVEMENT IN ANGIOGENESIS
1999 274: 35343-35350. [Abstract] [Full Text] [PDF]

Kimmo Tanhuanpää and Pentti Somerharju
gamma -Cyclodextrins Greatly Enhance Translocation of Hydrophobic Fluorescent Phospholipids from Vesicles to Cells in Culture. IMPORTANCE OF MOLECULAR HYDROPHOBICITY IN PHOSPHOLIPID TRAFFICKING STUDIES
1999 274: 35359-35366. [Abstract] [Full Text] [PDF]

Gerry T. Snoek, Christopher P. Berrie, Teunis B. H. Geijtenbeek, Hester A. van der Helm, Jenny A. Cadeé, Cristiano Iurisci, Daniela Corda, and Karel W. A. Wirtz
Overexpression of Phosphatidylinositol Transfer Protein alpha  in NIH3T3 Cells Activates a Phospholipase A
1999 274: 35393-35399. [Abstract] [Full Text] [PDF]

Stephanie Wragg and Kurt Drickamer
Identification of Amino Acid Residues That Determine pH Dependence of Ligand Binding to the Asialoglycoprotein Receptor during Endocytosis
1999 274: 35400-35406. [Abstract] [Full Text] [PDF]

Lígia O. Martins, Nuno Empadinhas, Joey D. Marugg, Carla Miguel, Célia Ferreira, Milton S. da Costa, and Helena Santos
Biosynthesis of Mannosylglycerate in the Thermophilic Bacterium Rhodothermus marinus. BIOCHEMICAL AND GENETIC CHARACTERIZATION OF A MANNOSYLGLYCERATE SYNTHASE
1999 274: 35407-35414. [Abstract] [Full Text] [PDF]

James D. Stockand, Bret J. Spier, Roger T. Worrell, Gang Yue, Nabil Al-Baldawi, and Douglas C. Eaton
Regulation of Na+ Reabsorption by the Aldosterone-induced Small G Protein K-Ras2A
1999 274: 35449-35454. [Abstract] [Full Text] [PDF]

Frank Kannenberg, Peter Ellinghaus, Gerd Assmann, and Udo Seedorf
Aberrant Oxidation of the Cholesterol Side Chain in Bile Acid Synthesis of Sterol Carrier Protein-2/Sterol Carrier Protein-x Knockout Mice
1999 274: 35455-35460. [Abstract] [Full Text] [PDF]

Paul R. Albert, Naghmeh Sajedi, Sylvie Lemonde, and Mohammad H. Ghahremani
Constitutive Gi2-dependent Activation of Adenylyl Cyclase Type II by the 5-HT1A Receptor. INHIBITION BY ANXIOLYTIC PARTIAL AGONISTS
1999 274: 35469-35474. [Abstract] [Full Text] [PDF]

Jun-ichi Sawada, Noriaki Simizu, Fumihiko Suzuki, Chika Sawa, Masahide Goto, Makoto Hasegawa, Takeshi Imai, Hajime Watanabe, and Hiroshi Handa
Synergistic Transcriptional Activation by hGABP and Select Members of the Activation Transcription Factor/cAMP Response Element-binding Protein Family
1999 274: 35475-35482. [Abstract] [Full Text] [PDF]

Patrik Raymond Jones, Birger Lindberg Møller, and Peter Bordier Høj
The UDP-glucose:p-Hydroxymandelonitrile-O-Glucosyltransferase That Catalyzes the Last Step in Synthesis of the Cyanogenic Glucoside Dhurrin in Sorghum bicolor. ISOLATION, CLONING, HETEROLOGOUS EXPRESSION, AND SUBSTRATE SPECIFICITY
1999 274: 35483-35491. [Abstract] [Full Text] [PDF]

Van-Anh T. Nguyen and Bin Gao
Cross-talk between alpha 1B-Adrenergic Receptor (alpha 1BAR) and Interleukin-6 (IL-6) Signaling Pathways. ACTIVATION OF alpha 1BAR INHIBITS IL-6-ACTIVATED STAT3 IN HEPATIC CELLS BY A p42/44 MITOGEN-ACTIVATED PROTEIN KINASE-DEPENDENT MECHANISM
1999 274: 35492-35498. [Abstract] [Full Text] [PDF]

Renae L. Malek, Zhongzhen Nie, Vickram Ramkumar, and Norman H. Lee
Adenosine A2A Receptor mRNA Regulation by Nerve Growth Factor Is TrkA-, Src-, and Ras-dependent via Extracellular Regulated Kinase and Stress-activated Protein Kinase/c-Jun NH2-terminal Kinase
1999 274: 35499-35504. [Abstract] [Full Text] [PDF]

Anping Chen, Bernard H. Davis, Marc Bissonnette, Beth Scaglione-Sewell, and Thomas A. Brasitus
1,25-Dihydroxyvitamin D3 Stimulates Activator Protein-1-dependent Caco-2 Cell Differentiation
1999 274: 35505-35513. [Abstract] [Full Text] [PDF]

Lorena Navarro and Michael David
p38-dependent Activation of Interferon Regulatory Factor 3 by Lipopolysaccharide
1999 274: 35535-35538. [Abstract] [Full Text] [PDF]

Jean-Louis Guillou, Hiroko Nakata, and Dermot M. F. Cooper
Inhibition by Calcium of Mammalian Adenylyl Cyclases
1999 274: 35539-35545. [Abstract] [Full Text] [PDF]

Prabha A. Ram and David J. Waxman
SOCS/CIS Protein Inhibition of Growth Hormone-stimulated STAT5 Signaling by Multiple Mechanisms
1999 274: 35553-35561. [Abstract] [Full Text] [PDF]

Anthony W. Ashton, Ryoji Yokota, Gareth John, Shumin Zhao, Sylvia O. Suadicani, David C. Spray, and J. Anthony Ware
Inhibition of Endothelial Cell Migration, Intercellular Communication, and Vascular Tube Formation by Thromboxane A2
1999 274: 35562-35570. [Abstract] [Full Text] [PDF]

Khaled A. H. Abo-Hashema, Max H. Cake, Glen W. Power, and Doug Clarke
Evidence for Triacylglycerol Synthesis in the Lumen of Microsomes via a Lipolysis-Esterification Pathway Involving Carnitine Acyltransferases
1999 274: 35577-35582. [Abstract] [Full Text] [PDF]

Luigi Puglielli and Carlos B. Hirschberg
Reconstitution, Identification, and Purification of the Rat Liver Golgi Membrane GDP-fucose Transporter
1999 274: 35596-35600. [Abstract] [Full Text] [PDF]

Jeffrey A. Engelman, Anders H. Berg, Renée Y. Lewis, Anning Lin, Michael P. Lisanti, and Philipp E. Scherer
Constitutively Active Mitogen-activated Protein Kinase Kinase 6 (MKK6) or Salicylate Induces Spontaneous 3T3-L1 Adipogenesis
1999 274: 35630-35638. [Abstract] [Full Text] [PDF]

Penny K. Davis and Gail V. W. Johnson
The Microtubule Binding of Tau and High Molecular Weight Tau in Apoptotic PC12 Cells Is Impaired because of Altered Phosphorylation
1999 274: 35686-35692. [Abstract] [Full Text] [PDF]

Melanija Tomic, Taka-aki Koshimizu, Davy Yuan, Silvana A. Andric, Dragoslava Zivadinovic, and Stanko S. Stojilkovic
Characterization of a Plasma Membrane Calcium Oscillator in Rat Pituitary Somatotrophs
1999 274: 35693-35702. [Abstract] [Full Text] [PDF]

Hiromi Hirata, Isao Yamamura, Kunihiko Yasuda, Akio Kobayashi, Norihiro Tada, Misao Suzuki, Kazunori Hirayoshi, Nobuko Hosokawa, and Kazuhiro Nagata
Separate Cis-acting DNA Elements Control Cell Type- and Tissue-specific Expression of Collagen Binding Molecular Chaperone HSP47
1999 274: 35703-35710. [Abstract] [Full Text] [PDF]

André Nantel, Maria Huber, and David Y. Thomas
Localization of Endogenous Grb10 to the Mitochondria and Its Interaction with the Mitochondrial-associated Raf-1 Pool
1999 274: 35719-35724. [Abstract] [Full Text] [PDF]

Gunter Schmidtke, Hermann-Georg Holzhütter, Matthew Bogyo, Norman Kairies, Michael Groll, Rita de Giuli, Sabine Emch, and Marcus Groettrup
How an Inhibitor of the HIV-I Protease Modulates Proteasome Activity
1999 274: 35734-35740. [Abstract] [Full Text] [PDF]

Toshiaki Nakajima, Tong Cheng, Andreas Rohrwasser, Laura J. Bloem, J. Howard Pratt, Ituro Inoue, and Jean-Marc Lalouel
Functional Analysis of a Mutation Occurring between the Two In-frame AUG Codons of Human Angiotensinogen
1999 274: 35749-35755. [Abstract] [Full Text] [PDF]

Gwynn M. Daniels and Susan G. Amara
Regulated Trafficking of the Human Dopamine Transporter. CLATHRIN-MEDIATED INTERNALIZATION AND LYSOSOMAL DEGRADATION IN RESPONSE TO PHORBOL ESTERS
1999 274: 35794-35801. [Abstract] [Full Text] [PDF]

William R. Tschantz, Lili Zhang, and Patrick J. Casey
Cloning, Expression, and Cellular Localization of a Human Prenylcysteine Lyase
1999 274: 35802-35808. [Abstract] [Full Text] [PDF]

Guyu Ho and Robert G. MacKenzie
Functional Characterization of Mutations in Melanocortin-4 Receptor Associated with Human Obesity
1999 274: 35816-35822. [Abstract] [Full Text] [PDF]

Supriya Srinivasan, Hannah Alexander, and Stephen Alexander
The Prespore Vesicles of Dictyostelium discoideum. PURIFICATION, CHARACTERIZATION, AND DEVELOPMENTAL REGULATION
1999 274: 35823-35831. [Abstract] [Full Text] [PDF]

Leigh B. MacMillan, Martha A. Bass, Nikki Cheng, Eric F. Howard, Masaaki Tamura, Stefan Strack, Brian E. Wadzinski, and Roger J. Colbran
Brain Actin-associated Protein Phosphatase 1 Holoenzymes Containing Spinophilin, Neurabin, and Selected Catalytic Subunit Isoforms
1999 274: 35845-35854. [Abstract] [Full Text] [PDF]

Karen L. Berg, Katherine A. Siminovitch, and E. Richard Stanley
SHP-1 Regulation of p62DOK Tyrosine Phosphorylation in Macrophages
1999 274: 35855-35865. [Abstract] [Full Text] [PDF]

Dongmei Cheng, Joyce Marner, and Peter A. Rubenstein
Interaction in Vivo and in Vitro between the Yeast Fimbrin, SAC6P, and a Polymerization-defective Yeast Actin (V266G and L267G)
1999 274: 35873-35880. [Abstract] [Full Text] [PDF]

Sharmila Basu-Modak, Olivier Braissant, Pascal Escher, Béatrice Desvergne, Paul Honegger, and Walter Wahli
Peroxisome Proliferator-activated Receptor beta  Regulates Acyl-CoA Synthetase 2 in Reaggregated Rat Brain Cell Cultures
1999 274: 35881-35888. [Abstract] [Full Text] [PDF]

Peter Michaely, Adeela Kamal, Richard G. W. Anderson, and Vann Bennett
A Requirement for Ankyrin Binding to Clathrin during Coated Pit Budding
1999 274: 35908-35913. [Abstract] [Full Text] [PDF]

Masahiko Akamatsu, Shin-ichi Aota, Akira Suwa, Kazumitsu Ueda, Teruo Amachi, Kenneth M. Yamada, Steven K. Akiyama, and Noriyuki Kioka
Vinexin Forms a Signaling Complex with Sos and Modulates Epidermal Growth Factor-induced c-Jun N-terminal Kinase/Stress-activated Protein Kinase Activities
1999 274: 35933-35937. [Abstract] [Full Text] [PDF]

Kristen L. Pierce, Hiromichi Fujino, Dinesh Srinivasan, and John W. Regan
Activation of FP Prostanoid Receptor Isoforms Leads to Rho-mediated Changes in Cell Morphology and in the Cell Cytoskeleton
1999 274: 35944-35949. [Abstract] [Full Text] [PDF]

Jeroen Van der Kaay, Matthias Beck, Alex Gray, and C. Peter Downes
Distinct Phosphatidylinositol 3-Kinase Lipid Products Accumulate upon Oxidative and Osmotic Stress and Lead to Different Cellular Responses
1999 274: 35963-35968. [Abstract] [Full Text] [PDF]

Sung-Oh Kim, Jon C. D. Houtman, Jing Jiang, J. Michael Ruppert, Paul J. Bertics, and Stuart J. Frank
Growth Hormone-induced Alteration in ErbB-2 Phosphorylation Status in 3T3-F442A Fibroblasts
1999 274: 36015-36024. [Abstract] [Full Text] [PDF]

Hiroyoshi Wada, Edward T. H. Yeh, and Tetsu Kamitani
The von Hippel-Lindau Tumor Suppressor Gene Product Promotes, but Is Not Essential for, NEDD8 Conjugation to Cullin-2
1999 274: 36025-36029. [Abstract] [Full Text] [PDF]


Enzymology

Heino Prinz, Arnon Lavie, Axel J. Scheidig, Oliver Spangenberg, and Manfred Konrad
Binding of Nucleotides to Guanylate Kinase, p21ras, and Nucleoside-diphosphate Kinase Studied by Nano-electrospray Mass Spectrometry
1999 274: 35337-35342. [Abstract] [Full Text] [PDF]

Bo Zhou and Zhong-Yin Zhang
Mechanism of Mitogen-activated Protein Kinase Phosphatase-3 Activation by ERK2
1999 274: 35526-35534. [Abstract] [Full Text] [PDF]

Kazuhiro Yamada, Seiki Yamada, Takamasa Tobimatsu, and Tetsuo Toraya
Heterologous High Level Expression, Purification, and Enzymological Properties of Recombinant Rat Cobalamin-dependent Methionine Synthase
1999 274: 35571-35576. [Abstract] [Full Text] [PDF]

Sergey A. Krupenko and Conrad Wagner
Aspartate 142 Is Involved in Both Hydrolase and Dehydrogenase Catalytic Centers of 10-Formyltetrahydrofolate Dehydrogenase
1999 274: 35777-35784. [Abstract] [Full Text] [PDF]

Dimitris Georgellis, Ohsuk Kwon, and Edmund C. C. Lin
Amplification of Signaling Activity of the Arc Two-component System of Escherichia coli by Anaerobic Metabolites. AN IN VITRO STUDY WITH DIFFERENT PROTEIN MODULES
1999 274: 35950-35954. [Abstract] [Full Text] [PDF]


Membranes and Bioenergetics

Tip W. Loo and David M. Clarke
Identification of Residues in the Drug-binding Domain of Human P-glycoprotein. ANALYSIS OF TRANSMEMBRANE SEGMENT 11 BY CYSTEINE-SCANNING MUTAGENESIS AND INHIBITION BY DIBROMOBIMANE
1999 274: 35388-35392. [Abstract] [Full Text] [PDF]

Ying-Hong Feng and Sadashiva S. Karnik
Role of Transmembrane Helix IV in G-protein Specificity of the Angiotensin II Type 1 Receptor
1999 274: 35546-35552. [Abstract] [Full Text] [PDF]

Linda L. Pearce, Bruce R. Pitt, and Jim Peterson
The Peroxynitrite Reductase Activity of Cytochrome c Oxidase Involves a Two-electron Redox Reaction at the Heme a3-CuB Site
1999 274: 35763-35767. [Abstract] [Full Text] [PDF]

Kirk G. Tanner and Jack Kyte
Dimerization of the Extracellular Domain of the Receptor for Epidermal Growth Factor Containing the Membrane-spanning Segment in Response to Treatment with Epidermal Growth Factor
1999 274: 35985-35990. [Abstract] [Full Text] [PDF]


Nucleic Acids, Protein Synthesis, and Molecular Genetics

Patrick Pei-chih Hu, Xing Shen, David Huang, Yueyi Liu, Christopher Counter, and Xiao-Fan Wang
The MEK Pathway Is Required for Stimulation of p21WAF1/CIP1 by Transforming Growth Factor-beta
1999 274: 35381-35387. [Abstract] [Full Text] [PDF]

Nancy J. Richter, George W. Rogers Jr., Jack O. Hensold, and William C. Merrick
Further Biochemical and Kinetic Characterization of Human Eukaryotic Initiation Factor 4H
1999 274: 35415-35424. [Abstract] [Full Text] [PDF]

Fei Chen, Laurence M. Demers, Val Vallyathan, Yongju Lu, Vincent Castranova, and Xianglin Shi
Involvement of 5'-Flanking kappa B-like Sites within bcl-x Gene in Silica-induced Bcl-x Expression
1999 274: 35591-35595. [Abstract] [Full Text] [PDF]

Brian A. Steer and Paul Schimmel
Major Anticodon-binding Region Missing from an Archaebacterial tRNA Synthetase
1999 274: 35601-35606. [Abstract] [Full Text] [PDF]

Frank J. Delfino and William H. Walker
NF-kappa B Induces cAMP-response Element-binding Protein Gene Transcription in Sertoli Cells
1999 274: 35607-35613. [Abstract] [Full Text] [PDF]

Ruth H. Palmer, Liselotte I. Fessler, Philip T. Edeen, Sanford J. Madigan, Michael McKeown, and Tony Hunter
DFak56 Is a Novel Drosophila melanogaster Focal Adhesion Kinase
1999 274: 35621-35629. [Abstract] [Full Text] [PDF]

Martine Vaxillaire, Amar Abderrahmani, Philippe Boutin, Bernard Bailleul, Philippe Froguel, Moshe Yaniv, and Marco Pontoglio
Anatomy of a Homeoprotein Revealed by the Analysis of Human MODY3 Mutations
1999 274: 35639-35646. [Abstract] [Full Text] [PDF]

Mark Nellist, Marjon A. van Slegtenhorst, Miriam Goedbloed, Ans M. W. van den Ouweland, Dicky J. J. Halley, and Peter van der Sluijs
Characterization of the Cytosolic Tuberin-Hamartin Complex. TUBERIN IS A CYTOSOLIC CHAPERONE FOR HAMARTIN
1999 274: 35647-35652. [Abstract] [Full Text] [PDF]

Qin Yan, Rodney J. Moreland, Joan Weliky Conaway, and Ronald C. Conaway
Dual Roles for Transcription Factor IIF in Promoter Escape by RNA Polymerase II
1999 274: 35668-35675. [Abstract] [Full Text] [PDF]

Shunbin Xu, Rahim Ladak, Deborah A. Swanson, Anna Soltyk, Hui Sun, Lynda Ploder, Danka Vidgen, Alessandra M. V. Duncan, Elizabeth Garami, David Valle, and Roderick R. McInnes
PHR1 Encodes an Abundant, Pleckstrin Homology Domain-containing Integral Membrane Protein in the Photoreceptor Outer Segments
1999 274: 35676-35685. [Abstract] [Full Text] [PDF]

Brian M. Shewchuk, Sylvia L. Asa, Nancy E. Cooke, and Stephen A. Liebhaber
Pit-1 Binding Sites at the Somatotrope-specific DNase I Hypersensitive Sites I, II of the Human Growth Hormone Locus Control Region Are Essential for in Vivo hGH-N Gene Activation
1999 274: 35725-35733. [Abstract] [Full Text] [PDF]

Ze-Guang Han, Qing-Hua Zhang, Min Ye, Li-Xin Kan, Bai-Wei Gu, Kai-Li He, Shao-Lin Shi, Jun Zhou, Gang Fu, Mao Mao, Sai-Juan Chen, Long Yu, and Zhu Chen
Molecular Cloning of Six Novel Krüppel-like Zinc Finger Genes from Hematopoietic Cells and Identification of a Novel Transregulatory Domain KRNB
1999 274: 35741-35748. [Abstract] [Full Text] [PDF]

Bruno Canard, Kajal Chowdhury, Robert Sarfati, Sylvie Doublié, and Charles C. Richardson
The Motif D Loop of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Is Critical for Nucleoside 5'-Triphosphate Selectivity
1999 274: 35768-35776. [Abstract] [Full Text] [PDF]

Patrick L. Sinn, Deborah R. Davis, and Curt D. Sigmund
Highly Regulated Cell Type-restricted Expression of Human Renin in Mice Containing 140- or 160-Kilobase Pair P1 Phage Artificial Chromosome Transgenes
1999 274: 35785-35793. [Abstract] [Full Text] [PDF]

Masaya Ueno, Hiroshi Masutani, Roberto Jun Arai, Akira Yamauchi, Kiichi Hirota, Toshiyuki Sakai, Takashi Inamoto, Yoshio Yamaoka, Junji Yodoi, and Toshio Nikaido
Thioredoxin-dependent Redox Regulation of p53-mediated p21 Activation
1999 274: 35809-35815. [Abstract] [Full Text] [PDF]

David N. Frick and Charles C. Richardson
Interaction of Bacteriophage T7 Gene 4 Primase with Its Template Recognition Site
1999 274: 35889-35898. [Abstract] [Full Text] [PDF]

David N. Frick, Shiv Kumar, and Charles C. Richardson
Interaction of Ribonucleoside Triphosphates with the Gene 4 Primase of Bacteriophage T7
1999 274: 35899-35907. [Abstract] [Full Text] [PDF]

Virginia E. Anderson, Richard P. Zaniewski, Frank S. Kaczmarek, Thomas D. Gootz, and Neil Osheroff
Quinolones Inhibit DNA Religation Mediated by Staphylococcus aureus Topoisomerase IV. CHANGES IN DRUG MECHANISM ACROSS EVOLUTIONARY BOUNDARIES
1999 274: 35927-35932. [Abstract] [Full Text] [PDF]

Deanna M. Janzen, Michael Y. Torgov, and Michael K. Reddy
In Vitro Reconstitution of the Bacteriophage T4 Clamp Loader Complex (gp44/62)
1999 274: 35938-35943. [Abstract] [Full Text] [PDF]

Haim Levy, Karen L. Kindle, and David B. Stern
Target and Specificity of a Nuclear Gene Product That Participates in mRNA 3'-End Formation in Chlamydomonas Chloroplasts
1999 274: 35955-35962. [Abstract] [Full Text] [PDF]

Martin Weinberger, Peter A. Trabold, Michael Lu, Karuna Sharma, Joel A. Huberman, and William C. Burhans
Induction by Adozelesin and Hydroxyurea of Origin Recognition Complex-dependent DNA Damage and DNA Replication Checkpoints in Saccharomyces cerevisiae
1999 274: 35975-35984. [Abstract] [Full Text] [PDF]

Md. Ruhul Abid, Yuan Li, Charles Anthony, and Arrigo De Benedetti
Translational Regulation of Ribonucleotide Reductase by Eukaryotic Initiation Factor 4E Links Protein Synthesis to the Control of DNA Replication
1999 274: 35991-35998. [Abstract] [Full Text] [PDF]

Tomoaki Ogino, Minako Iwama, Junko Kinouchi, Yoshio Shibagaki, Toshihiko Tsukamoto, and Kiyohisa Mizumoto
Involvement of a Cellular Glycolytic Enzyme, Phosphoglycerate Kinase, in Sendai Virus Transcription
1999 274: 35999-36008. [Abstract] [Full Text] [PDF]

Victor Kusnetsov, Martin Landsberger, Jörg Meurer, and Ralf Oelmüller
The Assembly of the CAAT-box Binding Complex at a Photosynthesis Gene Promoter Is Regulated by Light, Cytokinin, and the Stage of the Plastids
1999 274: 36009-36014. [Abstract] [Full Text] [PDF]


Protein Chemistry and Structure

Valérie Estienne, Christophe Blanchet, Patricia Niccoli-Sire, Christine Duthoit, Josée-Martine Durand-Gorde, Christophe Geourjon, Daniel Baty, Pierre Carayon, and Jean Ruf
Molecular Model, Calcium Sensitivity, and Disease Specificity of a Conformational Thyroperoxidase B-cell Epitope
1999 274: 35313-35317. [Abstract] [Full Text] [PDF]

Elizabeth R. Smith and Judith Storch
The Adipocyte Fatty Acid-binding Protein Binds to Membranes by Electrostatic Interactions
1999 274: 35325-35330. [Abstract] [Full Text] [PDF]

E. Sudharshan and A. G. Appu Rao
Involvement of Cysteine Residues and Domain Interactions in the Reversible Unfolding of Lipoxygenase-1
1999 274: 35351-35358. [Abstract] [Full Text] [PDF]

Kurt J. Amann, Athena W.-X. Guo, and James M. Ervasti
Utrophin Lacks the Rod Domain Actin Binding Activity of Dystrophin
1999 274: 35375-35380. [Abstract] [Full Text] [PDF]

Neal Stolowich, Andrey Frolov, Anca D. Petrescu, A. Ian Scott, Jeffrey T. Billheimer, and Friedhelm Schroeder
Holo-sterol Carrier Protein-2. 13C NMR INVESTIGATION OF CHOLESTEROL AND FATTY ACID BINDING SITES
1999 274: 35425-35433. [Abstract] [Full Text] [PDF]

Xiaonian Yang, Stephen T. Safrany, and Stephen B. Shears
Site-directed Mutagenesis of Diphosphoinositol Polyphosphate Phosphohydrolase, a Dual Specificity NUDT Enzyme That Attacks Diadenosine Polyphosphates and Diphosphoinositol Polyphosphates
1999 274: 35434-35440. [Abstract] [Full Text] [PDF]

Olivier M. Lardinois, Katalin F. Medzihradszky, and Paul R. Ortiz de Montellano
Spin Trapping and Protein Cross-linking of the Lactoperoxidase Protein Radical
1999 274: 35441-35448. [Abstract] [Full Text] [PDF]

J. Bradford Kline, Heather Roehrs, and Charles V. Clevenger
Functional Characterization of the Intermediate Isoform of the Human Prolactin Receptor
1999 274: 35461-35468. [Abstract] [Full Text] [PDF]

Marco W. Fraaije, Robert H. H. van den Heuvel, Willem J. H. van Berkel, and Andrea Mattevi
Covalent Flavinylation Is Essential for Efficient Redox Catalysis in Vanillyl-alcohol Oxidase
1999 274: 35514-35520. [Abstract] [Full Text] [PDF]

Ralph Wissmann, Thomas Baukrowitz, Hubert Kalbacher, Hans Robert Kalbitzer, J. Peter Ruppersberg, Olaf Pongs, Christoph Antz, and Bernd Fakler
NMR Structure and Functional Characteristics of the Hydrophilic N Terminus of the Potassium Channel beta -Subunit Kvbeta 1.1
1999 274: 35521-35525. [Abstract] [Full Text] [PDF]

Nancy A. Ayers, Deborah A. Wilkinson, Thomas J. Fitzgerald, and Gerald M. Carlson
Self-association of the alpha  Subunit of Phosphorylase Kinase as Determined by Two-hybrid Screening
1999 274: 35583-35590. [Abstract] [Full Text] [PDF]

Vesna Kostanjevecki, David Leys, Gonzalez Van Driessche, Terrance E. Meyer, Michael A. Cusanovich, Ulrich Fischer, Yves Guisez, and Jozef Van Beeumen
Structure and Characterization of Ectothiorhodospira vacuolata Cytochrome b558, a Prokaryotic Homologue of Cytochrome b5
1999 274: 35614-35620. [Abstract] [Full Text] [PDF]

Nicole Alessandri-Haber, Alain Lecoq, Sylvaine Gasparini, Geraldine Grangier-Macmath, Guy Jacquet, Alan L. Harvey, Cleane de Medeiros, Edward G. Rowan, Maurice Gola, André Ménez, and Marcel Crest
Mapping the Functional Anatomy of BgK on Kv1.1, Kv1.2, and Kv1.3. CLUES TO DESIGN ANALOGS WITH ENHANCED SELECTIVITY
1999 274: 35653-35661. [Abstract] [Full Text] [PDF]

Steven S. Broyles, Xu Liu, Min Zhu, and Marcia Kremer
Transcription Factor YY1 Is a Vaccinia Virus Late Promoter Activator
1999 274: 35662-35667. [Abstract] [Full Text] [PDF]

Hye-Ok Chung, Qing Yang, Kevin J. Catt, and Krishan K. Arora
Expression and Function of the Gonadotropin-releasing Hormone Receptor Are Dependent on a Conserved Apolar Amino Acid in the Third Intracellular Loop
1999 274: 35756-35762. [Abstract] [Full Text] [PDF]

Jessica L. Kosa and Joann B. Sweasy
The E249K Mutator Mutant of DNA Polymerase beta  Extends Mispaired Termini
1999 274: 35866-35872. [Abstract] [Full Text] [PDF]

Nenad Tomasevic and Brenda Peculis
Identification of a U8 snoRNA-specific Binding Protein
1999 274: 35914-35920. [Abstract] [Full Text] [PDF]

Dogaris Estavillo, Andrew Ritchie, Thomas G. Diacovo, and Miguel A. Cruz
Functional Analysis of a Recombinant Glycoprotein Ia/IIa (Integrin alpha 2beta 1) I Domain That Inhibits Platelet Adhesion to Collagen and Endothelial Matrix under Flow Conditions
1999 274: 35921-35926. [Abstract] [Full Text] [PDF]

Robin M. Delahay, Stuart Knutton, Robert K Shaw, Elizabeth L. Hartland, Mark J. Pallen, and Gad Frankel
The Coiled-coil Domain of EspA Is Essential for the Assembly of the Type III Secretion Translocon on the Surface of Enteropathogenic Escherichia coli
1999 274: 35969-35974. [Abstract] [Full Text] [PDF]


Additions and Corrections

Xiaoyin Shan, Liqun Wang, Roselle Hoffmaster, and Warren D. Kruger
Functional characterization of human methylenetetra- hydrofolate reductase in Saccharomyces cerevisiae.
1999 274: 36030. [Full Text] [PDF]

Craig S. Walker, Douglas Steel, Richard B. Jacobsen, Marcelina B. Lirazan, Lourdes J. Cruz, David Hooper, Reshma Shetty, Richard C. DelaCruz, Jacob S. Nielsen, Li Ming Zhou, Pradip Bandyopadhyay, A. Grey Craig, and Baldomero M. Olivera
The T-superfamily of conotoxins.
1999 274: 36030. [Full Text] [PDF]

Ilia Voskoboinik, Daniel Strausak, Mark Greenough, Hilary Brooks, Michael Petris, Suzanne Smith, Julian F. Mercer, and James Camakaris
Functional analysis of the N-terminal CXXC metal-binding motifs in the human Menkes copper-transporting P-type ATPase expressed in cultured mammalian cells.
1999 274: 36030. [Full Text] [PDF]


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