Communications

Kenichi Tanaka, Kaori Horiguchi, Toshinori Yoshida, Makio Takeda, Hideki Fujisawa, Kenichi Takeuchi, Masato Umeda, Sigeaki Kato, Sayoko Ihara, Satoshi Nagata, and Yasuhisa Fukui

Evidence That a Phosphatidylinositol 3,4,5-Trisphosphate-binding Protein Can Function in Nucleus
J. Biol. Chem. 1999 274: 3919-3922. [Abstract] [Full Text] [PDF]  

Thomas C. Evans Jr., Jack Benner, and Ming-Qun Xu

The in Vitro Ligation of Bacterially Expressed Proteins Using an Intein from Methanobacterium thermoautotrophicum
J. Biol. Chem. 1999 274: 3923-3926. [Abstract] [Full Text] [PDF]  

Lee Jamieson, Lee Carpenter, Trevor J. Biden, and Alan P. Fields

Protein Kinase C Activity Is Necessary for Bcr-Abl-mediated Resistance to Drug-induced Apoptosis
J. Biol. Chem. 1999 274: 3927-3930. [Abstract] [Full Text] [PDF]  

Kouichi Tanabe, Stephen J. Tucker, Michinori Matsuo, Peter Proks, Frances M. Ashcroft, Susumu Seino, Teruo Amachi, and Kazumitsu Ueda

Direct Photoaffinity Labeling of the Kir6.2 Subunit of the ATP-sensitive K⁺ Channel by 8-Azido-ATP
J. Biol. Chem. 1999 274: 3931-3933. [Abstract] [Full Text] [PDF]  

Steve Kriegler, Sterling Sudweeks, and Jerrel L. Yakel

The Nicotinic 4 Receptor Subunit Contributes to the Lining of the Ion Channel Pore When Expressed with the 5-HT₃ Receptor Subunit
J. Biol. Chem. 1999 274: 3934-3936. [Abstract] [Full Text] [PDF]  

Hua Xiao, Yong Tao, and Robert G. Roeder

The Human Homologue of Drosophila TRF-proximal Protein Is Associated with an RNA Polymerase II-SRB Complex
J. Biol. Chem. 1999 274: 3937-3940. [Abstract] [Full Text] [PDF]  

Carbohydrates, Lipids, and Other Natural Products

Joel A. Bozue, Michael V. Tullius, Jing Wang, Bradford W. Gibson, and Robert S. Munson Jr.

Haemophilus ducreyi Produces a Novel Sialyltransferase. IDENTIFICATION OF THE SIALYLTRANSFERASE GENE AND CONSTRUCTION OF MUTANTS DEFICIENT IN THE PRODUCTION OF THE SIALIC ACID-CONTAINING GLYCOFORM OF THE LIPOOLIGOSACCHARIDE
J. Biol. Chem. 1999 274: 4106-4114. [Abstract] [Full Text] [PDF]  

David L. Silver, Xian-cheng Jiang, and Alan R. Tall

Increased High Density Lipoprotein (HDL), Defective Hepatic Catabolism of ApoA-I and ApoA-II, and Decreased ApoA-I mRNA in ob/ob Mice. POSSIBLE ROLE OF LEPTIN IN STIMULATION OF HDL TURNOVER
J. Biol. Chem. 1999 274: 4140-4146. [Abstract] [Full Text] [PDF]  

Megumi Tandai-Hiruma, Tamao Endo, and Akira Kobata

Detection of Novel Carbohydrate Binding Activity of Interleukin-1
J. Biol. Chem. 1999 274: 4459-4466. [Abstract] [Full Text] [PDF]  

Cell Biology and Metabolism

Peter M. Haggie and Kevin M. Brindle

Mitochondrial Citrate Synthase Is Immobilized in Vivo
J. Biol. Chem. 1999 274: 3941-3945. [Abstract] [Full Text] [PDF]  

Shingo Kose, Naoko Imamoto, Taro Tachibana, Minoru Yoshida, and Yoshihiro Yoneda

-Subunit of Nuclear Pore-targeting Complex (Importin-) Can Be Exported from the Nucleus in a Ran-independent Manner
J. Biol. Chem. 1999 274: 3946-3952. [Abstract] [Full Text] [PDF]  

David A. Jans, Vivien R. Sutton, Patricia Jans, Christopher J. Froelich, and Joseph A. Trapani

BCL-2 Blocks Perforin-induced Nuclear Translocation of Granzymes Concomitant with Protection against the Nuclear Events of Apoptosis
J. Biol. Chem. 1999 274: 3953-3961. [Abstract] [Full Text] [PDF]  

Brigitte I. Frohnert, To Y. Hui, and David A. Bernlohr

Identification of a Functional Peroxisome Proliferator-responsive Element in the Murine Fatty Acid Transport Protein Gene
J. Biol. Chem. 1999 274: 3970-3977. [Abstract] [Full Text] [PDF]  

Regina Alemany, Dagmar Meyer zu Heringdorf, Chris J. van Koppen, and Karl H. Jakobs

Formyl Peptide Receptor Signaling in HL-60 Cells through Sphingosine Kinase
J. Biol. Chem. 1999 274: 3994-3999. [Abstract] [Full Text] [PDF]  

Angus I. Fletcher, Rongqing Shuang, David R. Giovannucci, Lin Zhang, Mary A. Bittner, and Edward L. Stuenkel

Regulation of Exocytosis by Cyclin-dependent Kinase 5 via Phosphorylation of Munc18
J. Biol. Chem. 1999 274: 4027-4035. [Abstract] [Full Text] [PDF]  

Michelle G. Mahon, Ken A. Lindstedt, Marcela Hermann, Johannes Nimpf, and Wolfgang J. Schneider

Multiple Involvement of Clusterin in Chicken Ovarian Follicle Development. BINDING TO TWO OOCYTE-SPECIFIC MEMBERS OF THE LOW DENSITY LIPOPROTEIN RECEPTOR GENE FAMILY
J. Biol. Chem. 1999 274: 4036-4044. [Abstract] [Full Text] [PDF]  

Owen W. Nadeau, Paul Domanski, Anna Usacheva, Shahab Uddin, Leonidas C. Platanias, Paula Pitha, Regina Raz, David Levy, Beata Majchrzak, Eleanor Fish, and Oscar R. Colamonici

The Proximal Tyrosines of the Cytoplasmic Domain of the  Chain of the Type I Interferon Receptor Are Essential for Signal Transducer and Activator of Transcription (Stat) 2 Activation. EVIDENCE THAT TWO Stat2 SITES ARE REQUIRED TO REACH A THRESHOLD OF INTERFERON -INDUCED Stat2 TYROSINE PHOSPHORYLATION THAT ALLOWS NORMAL FORMATION OF INTERFERON-STIMULATED GENE FACTOR 3
J. Biol. Chem. 1999 274: 4045-4052. [Abstract] [Full Text] [PDF]  

Oliver Rausch and Christopher J. Marshall

Cooperation of p38 and Extracellular Signal-regulated Kinase Mitogen-activated Protein Kinase Pathways during Granulocyte Colony-stimulating Factor-induced Hemopoietic Cell Proliferation
J. Biol. Chem. 1999 274: 4096-4105. [Abstract] [Full Text] [PDF]  

Xiao Quan Tian and Michael F. Holick

A Liposomal Model That Mimics the Cutaneous Production of Vitamin D₃. STUDIES OF THE MECHANISM OF THE MEMBRANE-ENHANCED THERMAL ISOMERIZATION OF PREVITAMIN D₃ TO VITAMIN D₃
J. Biol. Chem. 1999 274: 4174-4179. [Abstract] [Full Text] [PDF]  

Ludmil Benov and Irwin Fridovich

Why Superoxide Imposes an Aromatic Amino Acid Auxotrophy on Escherichia coli. THE TRANSKETOLASE CONNECTION
J. Biol. Chem. 1999 274: 4202-4206. [Abstract] [Full Text] [PDF]  

Jie Li, Kerstin Foitzik, Enzo Calautti, Howard Baden, Tom Doetschman, and G. Paolo Dotto

TGF-3, but Not TGF-1, Protects Keratinocytes against 12-O-Tetradecanoylphorbol-13-acetate-induced Cell Death in Vitro and in Vivo
J. Biol. Chem. 1999 274: 4213-4219. [Abstract] [Full Text] [PDF]  

Hans-Peter Mock, Werner Heller, Antonio Molina, Birgit Neubohn, Heinrich Sandermann Jr., and Bernhard Grimm

Expression of Uroporphyrinogen Decarboxylase or Coproporphyrinogen Oxidase Antisense RNA in Tobacco Induces Pathogen Defense Responses Conferring Increased Resistance to Tobacco Mosaic Virus
J. Biol. Chem. 1999 274: 4231-4238. [Abstract] [Full Text] [PDF]  

S. Celeste Posey and Barbara E. Bierer

Actin Stabilization by Jasplakinolide Enhances Apoptosis Induced by Cytokine Deprivation
J. Biol. Chem. 1999 274: 4259-4265. [Abstract] [Full Text] [PDF]  

Montserrat Vilella-Bach, Paul Nuzzi, Yimin Fang, and Jie Chen

The FKBP12-Rapamycin-binding Domain Is Required for FKBP12-Rapamycin-associated Protein Kinase Activity and G₁ Progression
J. Biol. Chem. 1999 274: 4266-4272. [Abstract] [Full Text] [PDF]  

Ted D. Chrisman and David L. Garbers

Reciprocal Antagonism Coordinates C-type Natriuretic Peptide and Mitogen-signaling Pathways in Fibroblasts
J. Biol. Chem. 1999 274: 4293-4299. [Abstract] [Full Text] [PDF]  

Carol Ward, Edwin R. Chilvers, Mark F. Lawson, James G. Pryde, Satoko Fujihara, Stuart N. Farrow, Christopher Haslett, and Adriano G. Rossi

NF-B Activation Is a Critical Regulator of Human Granulocyte Apoptosis in Vitro
J. Biol. Chem. 1999 274: 4309-4318. [Abstract] [Full Text] [PDF]  

Angelika Hoffmeyer, Anne Grosse-Wilde, Egbert Flory, Bernd Neufeld, Manfred Kunz, Ulf R. Rapp, and Stephan Ludwig

Different Mitogen-activated Protein Kinase Signaling Pathways Cooperate to Regulate Tumor Necrosis Factor  Gene Expression in T Lymphocytes
J. Biol. Chem. 1999 274: 4319-4327. [Abstract] [Full Text] [PDF]  

Kumiko Samejima, Phyllis A. Svingen, Guriqbal S. Basi, Timothy Kottke, Peter W. Mesner Jr., Lance Stewart, Françoise Durrieu, Guy G. Poirier, Emad S. Alnemri, James J. Champoux, Scott H. Kaufmann, and William C. Earnshaw

Caspase-mediated Cleavage of DNA Topoisomerase I at Unconventional Sites during Apoptosis
J. Biol. Chem. 1999 274: 4335-4340. [Abstract] [Full Text] [PDF]  

Ana Cuenda and Philip Cohen

Stress-activated Protein Kinase-2/p38 and a Rapamycin-sensitive Pathway Are Required for C2C12 Myogenesis
J. Biol. Chem. 1999 274: 4341-4346. [Abstract] [Full Text] [PDF]  

Lisa J. McCawley, Shunan Li, Elizabeth V. Wattenberg, and Laurie G. Hudson

Sustained Activation of the Mitogen-activated Protein Kinase Pathway. A MECHANISM UNDERLYING RECEPTOR TYROSINE KINASE SPECIFICITY FOR MATRIX METALLOPROTEINASE-9 INDUCTION AND CELL MIGRATION
J. Biol. Chem. 1999 274: 4347-4353. [Abstract] [Full Text] [PDF]  

Georg Kochs and Otto Haller

GTP-bound Human MxA Protein Interacts with the Nucleocapsids of Thogoto Virus (Orthomyxoviridae)
J. Biol. Chem. 1999 274: 4370-4376. [Abstract] [Full Text] [PDF]  

Meir Aridor, Sergei I. Bannykh, Tony Rowe, and William E. Balch

Cargo Can Modulate COPII Vesicle Formation from the Endoplasmic Reticulum
J. Biol. Chem. 1999 274: 4389-4399. [Abstract] [Full Text] [PDF]  

Chaoting Liu, Jin Yao, Ian de Belle, Ruo-Pan Huang, Eileen Adamson, and Dan Mercola

The Transcription Factor EGR-1 Suppresses Transformation of Human Fibrosarcoma HT1080 Cells by Coordinated Induction of Transforming Growth Factor-1, Fibronectin, and Plasminogen Activator Inhibitor-1
J. Biol. Chem. 1999 274: 4400-4411. [Abstract] [Full Text] [PDF]  

A. Douglas Laird, Deborah K. Morrison, and David Shalloway

Characterization of Raf-1 Activation in Mitosis
J. Biol. Chem. 1999 274: 4430-4439. [Abstract] [Full Text] [PDF]  

P. Jeanette Simpson, Alan Nighorn, and David B. Morton

Identification of a Novel Guanylyl Cyclase That Is Related to Receptor Guanylyl Cyclases, but Lacks Extracellular and Transmembrane Domains
J. Biol. Chem. 1999 274: 4440-4446. [Abstract] [Full Text] [PDF]  

Ildiko Toth, Liping Yuan, Jack T. Rogers, Hayden Boyce, and Kenneth R. Bridges

Hypoxia Alters Iron-regulatory Protein-1 Binding Capacity and Modulates Cellular Iron Homeostasis in Human Hepatoma and Erythroleukemia Cells
J. Biol. Chem. 1999 274: 4467-4473. [Abstract] [Full Text] [PDF]  

Luigi Puglielli, Elisabet C. Mandon, David M. Rancour, Anant K. Menon, and Carlos B. Hirschberg

Identification and Purification of the Rat Liver Golgi Membrane UDP-N-acetylgalactosamine Transporter
J. Biol. Chem. 1999 274: 4474-4479. [Abstract] [Full Text] [PDF]  

Enzymology

Paul Proost, Sofie Struyf, Dominique Schols, Ghislain Opdenakker, Silvano Sozzani, Paola Allavena, Alberto Mantovani, Koen Augustyns, Gunther Bal, Achiel Haemers, Anne-Marie Lambeir, Simon Scharpé, Jo Van Damme, and Ingrid De Meester

Truncation of Macrophage-derived Chemokine by CD26/ Dipeptidyl-Peptidase IV beyond Its Predicted Cleavage Site Affects Chemotactic Activity and CC Chemokine Receptor 4 Interaction
J. Biol. Chem. 1999 274: 3988-3993. [Abstract] [Full Text] [PDF]  

Slawomir Milewski, Danuta Kuszczak, Robert Jedrzejczak, Rachel J. Smith, Alistair J. P. Brown, and Graham W. Gooday

Oligomeric Structure and Regulation of Candida albicans Glucosamine-6-phosphate Synthase
J. Biol. Chem. 1999 274: 4000-4008. [Abstract] [Full Text] [PDF]  

Gary D. Johnson, Tracy Stevenson, and Kyunghye Ahn

Hydrolysis of Peptide Hormones by Endothelin-converting Enzyme-1. A COMPARISON WITH NEPRILYSIN
J. Biol. Chem. 1999 274: 4053-4058. [Abstract] [Full Text] [PDF]  

Zachary Shriver, Dongfang Liu, Yini Hu, and Ram Sasisekharan

Biochemical Investigations and Mapping of the Calcium-binding Sites of Heparinase I from Flavobacterium heparinum
J. Biol. Chem. 1999 274: 4082-4088. [Abstract] [Full Text] [PDF]  

Dongfang Liu, Zachary Shriver, Ranga Godavarti, Ganesh Venkataraman, and Ram Sasisekharan

The Calcium-binding Sites of Heparinase I from Flavobacterium heparinum Are Essential for Enzymatic Activity
J. Biol. Chem. 1999 274: 4089-4095. [Abstract] [Full Text] [PDF]  

Kengo Kanamaru, Rongchen Wang, Wenpei Su, and Nigel M. Crawford

Ser-534 in the Hinge 1 Region of Arabidopsis Nitrate Reductase Is Conditionally Required for Binding of 14-3-3 Proteins and in Vitro Inhibition
J. Biol. Chem. 1999 274: 4160-4165. [Abstract] [Full Text] [PDF]  

Akira Watababe, Yoichi Kurokawa, Tohru Yoshimura, Tatsuo Kurihara, Kenji Soda, and Nobuyoshi Esaki

Role of Lysine 39 of Alanine Racemase from Bacillus stearothermophilus That Binds Pyridoxal 5'-Phosphate. CHEMICAL RESCUE STUDIES OF Lys³⁹  Ala MUTANT
J. Biol. Chem. 1999 274: 4189-4194. [Abstract] [Full Text] [PDF]  

Valarie L. Tlapak-Simmons, Bruce A. Baggenstoss, Tracy Clyne, and Paul H. Weigel

Purification and Lipid Dependence of the Recombinant Hyaluronan Synthases from Streptococcus pyogenes and Streptococcus equisimilis
J. Biol. Chem. 1999 274: 4239-4245. [Abstract] [Full Text] [PDF]  

Valarie L. Tlapak-Simmons, Bruce A. Baggenstoss, Kshama Kumari, Coy Heldermon, and Paul H. Weigel

Kinetic Characterization of the Recombinant Hyaluronan Synthases from Streptococcus pyogenes and Streptococcus equisimilis
J. Biol. Chem. 1999 274: 4246-4253. [Abstract] [Full Text] [PDF]  

Axel Schmidt, Rudi Grimm, Jürgen Schmidt, Dierk Scheel, Dieter Strack, and Sabine Rosahl

Cloning and Expression of a Potato cDNA Encoding Hydroxycinnamoyl-CoA:Tyramine N-(Hydroxycinnamoyl)transferase
J. Biol. Chem. 1999 274: 4273-4280. [Abstract] [Full Text] [PDF]  

Lixin Yu, Frank R. DeLeo, Karla J. Biberstine-Kinkade, Jan Renee, William M. Nauseef, and Mary C. Dinauer

Biosynthesis of Flavocytochrome b₅₅₈. gp91^phox IS SYNTHESIZED AS A 65-kDa PRECURSOR (p65) IN THE ENDOPLASMIC RETICULUM
J. Biol. Chem. 1999 274: 4364-4369. [Abstract] [Full Text] [PDF]  

Membranes and Bioenergetics

Hui Zhao, Michael R. Wiederkehr, Lingzhi Fan, Roberto L. Collazo, Ladonna A. Crowder, and Orson W. Moe

Acute Inhibition of Na/H Exchanger NHE-3 by cAMP. ROLE OF PROTEIN KINASE A AND NHE-3 PHOSPHOSERINES 552 AND 605
J. Biol. Chem. 1999 274: 3978-3987. [Abstract] [Full Text] [PDF]  

Simon J. Thompson, Colin Robinson, and Alexandra Mant

Dual Signal Peptides Mediate the Signal Recognition Particle/Sec-independent Insertion of a Thylakoid Membrane Polyprotein, PsbY
J. Biol. Chem. 1999 274: 4059-4066. [Abstract] [Full Text] [PDF]  

Jerry L. Johnson and Robert J. Brooker

A K319N/E325Q Double Mutant of the Lactose Permease Cotransports H⁺ with Lactose. IMPLICATIONS FOR A PROPOSED MECHANISM OF H⁺/LACTOSE SYMPORT
J. Biol. Chem. 1999 274: 4074-4081. [Abstract] [Full Text] [PDF]  

Alexander Kraev, Natalia Kraev, and Ernesto Carafoli

Identification and Functional Expression of the Plasma Membrane Calcium ATPase Gene Family from Caenorhabditis elegans
J. Biol. Chem. 1999 274: 4254-4258. [Abstract] [Full Text] [PDF]  

Nancy R. Baird, John Orlowski, Elöd Z. Szabó, Hans C. Zaun, Patrick J. Schultheis, Anil G. Menon, and Gary E. Shull

Molecular Cloning, Genomic Organization, and Functional Expression of Na⁺/H⁺ Exchanger Isoform 5 (NHE5) from Human Brain
J. Biol. Chem. 1999 274: 4377-4382. [Abstract] [Full Text] [PDF]  

Surat Attaphitaya, Keerang Park, and James E. Melvin

Molecular Cloning and Functional Expression of a Rat Na⁺/H⁺ Exchanger (NHE5) Highly Expressed in Brain
J. Biol. Chem. 1999 274: 4383-4388. [Abstract] [Full Text] [PDF]  

Nucleic Acids, Protein Synthesis, and Molecular Genetics

Erwin Blum, Agamemnon J. Carpousis, and Christopher F. Higgins

Polyadenylation Promotes Degradation of 3'-Structured RNA by the Escherichia coli mRNA Degradosome in Vitro
J. Biol. Chem. 1999 274: 4009-4016. [Abstract] [Full Text] [PDF]  

Axel Scholz, Mathias Truss, and Miguel Beato

Hormone-dependent Recruitment of NF-Y to the Uteroglobin Gene Enhancer Associated with Chromatin Remodeling in Rabbit Endometrial Epithelium
J. Biol. Chem. 1999 274: 4017-4026. [Abstract] [Full Text] [PDF]  

Ghylène Goudet, Sylvie Delhalle, Frédéric Biemar, Joseph A. Martial, and Bernard Peers

Functional and Cooperative Interactions between the Homeodomain PDX1, Pbx, and Prep1 Factors on the Somatostatin Promoter
J. Biol. Chem. 1999 274: 4067-4073. [Abstract] [Full Text] [PDF]  

Beate Ritz-Laser, Anne Estreicher, Natacha Klages, Simon Saule, and Jacques Philippe

Pax-6 and Cdx-2/3 Interact to Activate Glucagon Gene Expression on the G₁ Control Element
J. Biol. Chem. 1999 274: 4124-4132. [Abstract] [Full Text] [PDF]  

Nicholas D. Angerer, Yang Du, Demet Nalbant, and Simon C. Williams

A Short Conserved Motif Is Required for Repressor Domain Function in the Myeloid-specific Transcription Factor CCAAT/Enhancer-binding Protein
J. Biol. Chem. 1999 274: 4147-4154. [Abstract] [Full Text] [PDF]  

Simi T. Hurst and David H. Rivier

Identification of a Compound Origin of Replication at the HMR-E Locus in Saccharomyces cerevisiae
J. Biol. Chem. 1999 274: 4155-4159. [Abstract] [Full Text] [PDF]  

Kristin F. Wilson, Puri Fortes, Ugra S. Singh, Mutsuhito Ohno, Iain W. Mattaj, and Richard A. Cerione

The Nuclear Cap-binding Complex Is a Novel Target of Growth Factor Receptor-coupled Signal Transduction
J. Biol. Chem. 1999 274: 4166-4173. [Abstract] [Full Text] [PDF]  

John A. Chiorini, Suzanne Miyamoto, Stephanie J. Harkin, and Brian Safer

Genomic Cloning and Characterization of the Human Eukaryotic Initiation Factor-2 Promoter
J. Biol. Chem. 1999 274: 4195-4201. [Abstract] [Full Text] [PDF]  

Alpana Ray, Heide Schatten, and Bimal K. Ray

Activation of Sp1 and Its Functional Co-operation with Serum Amyloid A-activating Sequence Binding Factor in Synoviocyte Cells Trigger Synergistic Action of Interleukin-1 and Interleukin-6 in Serum Amyloid A Gene Expression
J. Biol. Chem. 1999 274: 4300-4308. [Abstract] [Full Text] [PDF]  

Hadi M. Alzuherri and Robert J. White

Regulation of RNA Polymerase I Transcription in Response to F9 Embryonal Carcinoma Stem Cell Differentiation
J. Biol. Chem. 1999 274: 4328-4334. [Abstract] [Full Text] [PDF]  

Ronald Gary, Kyung Kim, Helen L. Cornelius, Min S. Park, and Yoshihiro Matsumoto

Proliferating Cell Nuclear Antigen Facilitates Excision in Long-patch Base Excision Repair
J. Biol. Chem. 1999 274: 4354-4363. [Abstract] [Full Text] [PDF]  

Sylvie Auxilien, Gérard Keith, Stuart F. J. Le Grice, and Jean-Luc Darlix

Role of Post-transcriptional Modifications of Primer tRNA^Lys,3 in the Fidelity and Efficacy of Plus Strand DNA Transfer during HIV-1 Reverse Transcription
J. Biol. Chem. 1999 274: 4412-4420. [Abstract] [Full Text] [PDF]  

Erik T. Fouts, Xiong Yu, Edward H. Egelman, and Michael R. Botchan

Biochemical and Electron Microscopic Image Analysis of the Hexameric E1 Helicase
J. Biol. Chem. 1999 274: 4447-4458. [Abstract] [Full Text] [PDF]  

Protein Chemistry and Structure

Chiara Rodighiero, Abu T. Aman, Martin J. Kenny, Joel Moss, Wayne I. Lencer, and Timothy R. Hirst

Structural Basis for the Differential Toxicity of Cholera Toxin and Escherichia coli Heat-labile Enterotoxin. CONSTRUCTION OF HYBRID TOXINS IDENTIFIES THE A2-DOMAIN AS THE DETERMINANT OF DIFFERENTIAL TOXICITY
J. Biol. Chem. 1999 274: 3962-3969. [Abstract] [Full Text] [PDF]  

Peter D. Kwong, Richard Wyatt, Elizabeth Desjardins, James Robinson, Jeffrey S. Culp, Brian D. Hellmig, Raymond W. Sweet, Joseph Sodroski, and Wayne A. Hendrickson

Probability Analysis of Variational Crystallization and Its Application to gp120, The Exterior Envelope Glycoprotein of Type 1 Human Immunodeficiency Virus (HIV-1)
J. Biol. Chem. 1999 274: 4115-4123. [Abstract] [Full Text] [PDF]  

Ahmed Chadli, Moncef M. Ladjimi, Etienne-Emile Baulieu, and Maria Grazia Catelli

Heat-induced Oligomerization of the Molecular Chaperone Hsp90. INHIBITION BY ATP AND GELDANAMYCIN AND ACTIVATION BY TRANSITION METAL OXYANIONS
J. Biol. Chem. 1999 274: 4133-4139. [Abstract] [Full Text] [PDF]  

Michael Hippler, Friedrich Drepper, Jean-David Rochaix, and Ulrich Mühlenhoff

Insertion of the N-terminal Part of PsaF from Chlamydomonas reinhardtii into Photosystem I from Synechococcus elongatus Enables Efficient Binding of Algal Plastocyanin and Cytochrome c₆
J. Biol. Chem. 1999 274: 4180-4188. [Abstract] [Full Text] [PDF]  

Tapan Kanti Das, H. Caroline Lee, Stephen M. G. Duff, Robert D. Hill, Jack Peisach, Denis L. Rousseau, Beatrice A. Wittenberg, and Jonathan B. Wittenberg

The Heme Environment in Barley Hemoglobin
J. Biol. Chem. 1999 274: 4207-4212. [Abstract] [Full Text] [PDF]  

Tadaaki Kishi, Masato Kato, Toshiyuki Shimizu, Keiko Kato, Kazumasa Matsumoto, Shigetaka Yoshida, Sadao Shiosaka, and Toshio Hakoshima

Crystal Structure of Neuropsin, a Hippocampal Protease Involved in Kindling Epileptogenesis
J. Biol. Chem. 1999 274: 4220-4224. [Abstract] [Full Text] [PDF]  

Naoki Shibata, Tsuyoshi Inoue, Chizuko Nagano, Nobuya Nishio, Takamitsu Kohzuma, Kazuhiko Onodera, Fuminori Yoshizaki, Yasutomo Sugimura, and Yasushi Kai

Novel Insight into the Copper-Ligand Geometry in the Crystal Structure of Ulva pertusa Plastocyanin at 1.6-Å Resolution. STRUCTURAL BASIS FOR REGULATION OF THE COPPER SITE BY RESIDUE 88
J. Biol. Chem. 1999 274: 4225-4230. [Abstract] [Full Text] [PDF]  

Günter Harth and Marcus A. Horwitz

Export of Recombinant Mycobacterium tuberculosis Superoxide Dismutase Is Dependent upon Both Information in the Protein and Mycobacterial Export Machinery. A MODEL FOR STUDYING EXPORT OF LEADERLESS PROTEINS BY PATHOGENIC MYCOBACTERIA
J. Biol. Chem. 1999 274: 4281-4292. [Abstract] [Full Text] [PDF]  

Christopher M. Overall, Angela E. King, Douglas K. Sam, Aldrich D. Ong, Tim T. Y. Lau, U. Margaretha Wallon, Yves A. DeClerck, and Juliet Atherstone

Identification of the Tissue Inhibitor of Metalloproteinases-2 (TIMP-2) Binding Site on the Hemopexin Carboxyl Domain of Human Gelatinase A by Site-directed Mutagenesis. THE HIERARCHICAL ROLE IN BINDING TIMP-2 OF THE UNIQUE CATIONIC CLUSTERS OF HEMOPEXIN MODULES III AND IV
J. Biol. Chem. 1999 274: 4421-4429. [Abstract] [Full Text] [PDF]  

Additions and Corrections

Catherine C. Y. Chang, Chi-Yu Gregory Lee, Ellen T. Chang, Jonathan C. Cruz, Marc C. Levesque, and Ta-Yuan Chang

Additions and Corrections to Recombinant acyl-CoA:cholesterol acyltransferase-1 (ACAT-1) purified to essential homogeneity utilizes cholesterol in mixed micelles or in vesicles in a highly cooperative manner.
J. Biol. Chem. 1999 274: 4480. [Full Text] [PDF]  

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