Accelerated Publications:

Brandee L. Wagner, Anton Bauer, Günther Schütz, and Marc Montminy

Stimulus-specific Interaction between Activator-Coactivator Cognates Revealed with a Novel Complex-specific Antiserum
J. Biol. Chem. 2000 275: 8263-8266. [Abstract] [Full Text] [PDF]  

Shuting Bai, Xingming Shi, Xiangli Yang, and Xu Cao

Smad6 as a Transcriptional Corepressor
J. Biol. Chem. 2000 275: 8267-8270. [Abstract] [Full Text] [PDF]  

Alex Toker and Alexandra C. Newton

Akt/Protein Kinase B Is Regulated by Autophosphorylation at the Hypothetical PDK-2 Site
J. Biol. Chem. 2000 275: 8271-8274. [Abstract] [Full Text] [PDF]  

Christopher L. Fong, Amy Lentz, and Stephen P. Mayfield

Disulfide Bond Formation between RNA Binding Domains Is Used to Regulate mRNA Binding Activity of the Chloroplast Poly(A)-binding Protein
J. Biol. Chem. 2000 275: 8275-8278. [Abstract] [Full Text] [PDF]  

Dmitrii G. Rodionov, Tommy W. Nordeng, Thomas L. Kongsvik, and Oddmund Bakke

The Cytoplasmic Tail of CD1d Contains Two Overlapping Basolateral Sorting Signals
J. Biol. Chem. 2000 275: 8279-8282. [Abstract] [Full Text] [PDF]  

Peter M. Palenchar, Christopher J. Buck, Hui Cheng, Timothy J. Larson, and Eugene G. Mueller

Evidence That ThiI, an Enzyme Shared between Thiamin and 4-Thiouridine Biosynthesis, May Be a Sulfurtransferase That Proceeds through a Persulfide Intermediate
J. Biol. Chem. 2000 275: 8283-8286. [Abstract] [Full Text] [PDF]  

Jui-Yoa Chang, Li Li, and Alexey Bulychev

The Underlying Mechanism for the Diversity of Disulfide Folding Pathways
J. Biol. Chem. 2000 275: 8287-8289. [Abstract] [Full Text] [PDF]  

DNA: Replication Repair and Recombination:

Anton Tevelev and David G. Schatz

Intermolecular V(D)J Recombination
J. Biol. Chem. 2000 275: 8341-8348. [Abstract] [Full Text] [PDF]  

Domenico Maiorano, Jean-Marc Lemaître, and Marcel Méchali

Stepwise Regulated Chromatin Assembly of MCM2-7 Proteins
J. Biol. Chem. 2000 275: 8426-8431. [Abstract] [Full Text] [PDF]  

Xianghong Li, Patrick M. Wright, and A-Lien Lu

The C-terminal Domain of MutY Glycosylase Determines the 7,8-Dihydro-8-oxo-guanine Specificity and Is Crucial for Mutation Avoidance
J. Biol. Chem. 2000 275: 8448-8455. [Abstract] [Full Text] [PDF]  

Genes: Structure and Regulation:

Xu Feng, Steven L. Teitelbaum, Marisol E. Quiroz, Su-Li Cheng, Chung-Fang Lai, Louis V. Avioli, and F. Patrick Ross

Sp1/Sp3 and PU.1 Differentially Regulate ₅ Integrin Gene Expression in Macrophages and Osteoblasts
J. Biol. Chem. 2000 275: 8331-8340. [Abstract] [Full Text] [PDF]  

Manolis Papamichos-Chronakis, R. Steven Conlan, Niki Gounalaki, Tjana Copf, and Dimitris Tzamarias

Hrs1/Med3 Is a Cyc8-Tup1 Corepressor Target in the RNA Polymerase II Holoenzyme
J. Biol. Chem. 2000 275: 8397-8403. [Abstract] [Full Text] [PDF]  

Anne Chauchereau, Maria Georgiakaki, Mallory Perrin-Wolff, Edwin Milgrom, and Hugues Loosfelt

JAB1 Interacts with Both the Progesterone Receptor and SRC-1
J. Biol. Chem. 2000 275: 8540-8548. [Abstract] [Full Text] [PDF]  

Jong Seok Kang and Jin-Soo Kim

Zinc Finger Proteins as Designer Transcription Factors
J. Biol. Chem. 2000 275: 8742-8748. [Abstract] [Full Text] [PDF]  

Jianhua Zhang, Qing-Yu Zhang, Jiancheng Guo, Yali Zhou, and Xinxin Ding

Identification and Functional Characterization of a Conserved, Nuclear Factor 1-like Element in the Proximal Promoter Region of CYP1A2 Gene Specifically Expressed in the Liver and Olfactory Mucosa
J. Biol. Chem. 2000 275: 8895-8902. [Abstract] [Full Text] [PDF]  

Ji-liang Zhao, K. Frank Austen, and Bing K. Lam

Cell-specific Transcription of Leukotriene C₄ Synthase Involves a Kruppel-like Transcription Factor and Sp1
J. Biol. Chem. 2000 275: 8903-8910. [Abstract] [Full Text] [PDF]  

Peter Fax, Kai S. Lipinski, Helmut Esche, and Dieter Brockmann

cAMP-independent Activation of the Adenovirus Type 12 E2 Promoter Correlates with the Recruitment of CREB-1/ATF-1, E1A_12S, and CBP to the E2-CRE
J. Biol. Chem. 2000 275: 8911-8920. [Abstract] [Full Text] [PDF]  

John D. Noti, Andrew K. Johnson, and Jill D. Dillon

Structural and Functional Characterization of the Leukocyte Integrin Gene CD11d. ESSENTIAL ROLE OF Sp1 AND Sp3
J. Biol. Chem. 2000 275: 8959-8969. [Abstract] [Full Text] [PDF]  

Carole Jabet, Elizabeth R. Sprague, Andrew P. VanDemark, and Cynthia Wolberger

Characterization of the N-terminal Domain of the Yeast Transcriptional Repressor Tup1. PROPOSAL FOR AN ASSOCIATION MODEL OF THE REPRESSOR COMPLEX Tup1·Ssn6
J. Biol. Chem. 2000 275: 9011-9018. [Abstract] [Full Text] [PDF]  

Florian Then Bergh, Elizabeth M. Flinn, John Svaren, Anthony P. Wright, and Wolfram Hörz

Comparison of Nucleosome Remodeling by the Yeast Transcription Factor Pho4 and the Glucocorticoid Receptor
J. Biol. Chem. 2000 275: 9035-9042. [Abstract] [Full Text] [PDF]  

Talat Afroze and Mansoor Husain

c-Myb-binding Sites Mediate G₁/S-associated Repression of the Plasma Membrane Ca²⁺-ATPase-1 Promoter
J. Biol. Chem. 2000 275: 9062-9069. [Abstract] [Full Text] [PDF]  

RNA: Structure Metabolism and Catalysis:

Mark R. Tock, Andrew P. Walsh, Gregory Carroll, and Kenneth J. McDowall

The CafA Protein Required for the 5'-Maturation of 16 S rRNA Is a 5'-End-dependent Ribonuclease That Has Context-dependent Broad Sequence Specificity
J. Biol. Chem. 2000 275: 8726-8732. [Abstract] [Full Text] [PDF]  

Xiao-Ling Li, John A. Blackford, Carianne S. Judge, Mingjuan Liu, Weihua Xiao, Dhananjaya V. Kalvakolanu, and Bret A. Hassel

RNase-L-dependent Destabilization of Interferon-induced mRNAs. A ROLE FOR THE 2-5A SYSTEM IN ATTENUATION OF THE INTERFERON RESPONSE
J. Biol. Chem. 2000 275: 8880-8888. [Abstract] [Full Text] [PDF]  

Protein Synthesis Post-Translation Modification and Degradation:

Qiang Ma and Kimberly T. Baldwin

2,3,7,8-Tetrachlorodibenzo-p-dioxin-induced Degradation of Aryl Hydrocarbon Receptor (AhR) by the Ubiquitin-Proteasome Pathway. ROLE OF THE TRANSCRIPTION ACTIVATON AND DNA BINDING OF AhR
J. Biol. Chem. 2000 275: 8432-8438. [Abstract] [Full Text] [PDF]  

Annapurna Korimilli, Linda W. Gonzales, and Susan H. Guttentag

Intracellular Localization of Processing Events in Human Surfactant Protein B Biosynthesis
J. Biol. Chem. 2000 275: 8672-8679. [Abstract] [Full Text] [PDF]  

Lilia Z. Topol, Boris Bardot, Qingyun Zhang, James Resau, Emmanuelle Huillard, Maria Marx, Georges Calothy, and Donald G. Blair

Biosynthesis, Post-translation Modification, and Functional Characterization of Drm/Gremlin
J. Biol. Chem. 2000 275: 8785-8793. [Abstract] [Full Text] [PDF]  

Anne Snellman, Marja-Riitta Keränen, Pasi O. Hägg, Arja Lamberg, J. Kalervo Hiltunen, Kari I. Kivirikko, and Taina Pihlajaniemi

Type XIII Collagen Forms Homotrimers with Three Triple Helical Collagenous Domains and Its Association into Disulfide-bonded Trimers Is Enhanced by Prolyl 4-Hydroxylase
J. Biol. Chem. 2000 275: 8936-8944. [Abstract] [Full Text] [PDF]  

Shengyun Fang, Jane P. Jensen, Robert L. Ludwig, Karen H. Vousden, and Allan M. Weissman

Mdm2 Is a RING Finger-dependent Ubiquitin Protein Ligase for Itself and p53
J. Biol. Chem. 2000 275: 8945-8951. [Abstract] [Full Text] [PDF]  

Patrice Decker, David Isenberg, and Sylviane Muller

Inhibition of Caspase-3-mediated Poly(ADP-ribose) Polymerase (PARP) Apoptotic Cleavage by Human PARP Autoantibodies and Effect on Cells Undergoing Apoptosis
J. Biol. Chem. 2000 275: 9043-9046. [Abstract] [Full Text] [PDF]  

Protein Structure and Folding:

Jedrzej Malecki, Agnieszka Polit, and Zygmunt Wasylewski

Kinetic Studies of cAMP-induced Allosteric Changes in Cyclic AMP Receptor Protein from Escherichia coli
J. Biol. Chem. 2000 275: 8480-8486. [Abstract] [Full Text] [PDF]  

Jee-Hyun Cho, K. Hun Mok, Baldomero M. Olivera, J. Michael McIntosh, Kyu-Hwan Park, and Kyou-Hoon Han

Nuclear Magnetic Resonance Solution Conformation of -Conotoxin AuIB, an ₃₄ Subtype-selective Neuronal Nicotinic Acetylcholine Receptor Antagonist
J. Biol. Chem. 2000 275: 8680-8685. [Abstract] [Full Text] [PDF]  

Katrin Ridinger, Beat W. Schäfer, Isabelle Durussel, Jos A. Cox, and Claus W. Heizmann

S100A13. BIOCHEMICAL CHARACTERIZATION AND SUBCELLULAR LOCALIZATION IN DIFFERENT CELL LINES
J. Biol. Chem. 2000 275: 8686-8694. [Abstract] [Full Text] [PDF]  

Tetsuro Yahata, Mark P. de Caestecker, Robert J. Lechleider, Stephanie Andriole, Anita B. Roberts, Kurt J. Isselbacher, and Toshi Shioda

The MSG1 Non-DNA-binding Transactivator Binds to the p300/CBP Coactivators, Enhancing Their Functional Link to the Smad Transcription Factors
J. Biol. Chem. 2000 275: 8825-8834. [Abstract] [Full Text] [PDF]  

Paul Emsley, Constantina Fotinou, Isobel Black, Neil F. Fairweather, Ian G. Charles, Colin Watts, Eric Hewitt, and Neil W. Isaacs

The Structures of the H_C Fragment of Tetanus Toxin with Carbohydrate Subunit Complexes Provide Insight into Ganglioside Binding
J. Biol. Chem. 2000 275: 8889-8894. [Abstract] [Full Text] [PDF]  

Thomas Klausberger, Karoline Fuchs, Bernd Mayer, Noosha Ehya, and Werner Sieghart

GABA_A Receptor Assembly. IDENTIFICATION AND STRUCTURE OF ₂ SEQUENCES FORMING THE INTERSUBUNIT CONTACTS WITH ₁ AND ₃ SUBUNITS
J. Biol. Chem. 2000 275: 8921-8928. [Abstract] [Full Text] [PDF]  

Ke Gong, Lynn Mailloux, and Mark C. Herzberg

Salivary Film Expresses a Complex, Macromolecular Binding Site for Streptococcus sanguis
J. Biol. Chem. 2000 275: 8970-8974. [Abstract] [Full Text] [PDF]  

Yasufumi Minami, Hiroshi Kawasaki, Michiko Minami, Nobuyuki Tanahashi, Keiji Tanaka, and Ichiro Yahara

A Critical Role for the Proteasome Activator PA28 in the Hsp90-dependent Protein Refolding
J. Biol. Chem. 2000 275: 9055-9061. [Abstract] [Full Text] [PDF]  

Enzyme Catalysis and Regulation:

Xinlin Du, Heinz Frei, and Sung-Hou Kim

The Mechanism of GTP Hydrolysis by Ras Probed by Fourier Transform Infrared Spectroscopy
J. Biol. Chem. 2000 275: 8492-8500. [Abstract] [Full Text] [PDF]  

Elizabeth D. Thuresson, Karen M. Lakkides, and William L. Smith

Different Catalytically Competent Arrangements of Arachidonic Acid within the Cyclooxygenase Active Site of Prostaglandin Endoperoxide H Synthase-1 Lead to the Formation of Different Oxygenated Products
J. Biol. Chem. 2000 275: 8501-8507. [Abstract] [Full Text] [PDF]  

Judy Hirst and David B. Goodin

Unusual Oxidative Chemistry of N-Hydroxyarginine and N-Hydroxyguanidine Catalyzed at an Engineered Cavity in a Heme Peroxidase
J. Biol. Chem. 2000 275: 8582-8591. [Abstract] [Full Text] [PDF]  

Per Jemth and Bengt Mannervik

Active Site Serine Promotes Stabilization of the Reactive Glutathione Thiolate in Rat Glutathione Transferase T2-2. EVIDENCE AGAINST PROPOSED SULFATASE ACTIVITY OF THE CORRESPONDING HUMAN ENZYME
J. Biol. Chem. 2000 275: 8618-8624. [Abstract] [Full Text] [PDF]  

Young-Chul Choi, Geon Tae Park, Tai-Seung Kim, Il-Nam Sunwoo, Peter M. Steinert, and Soo-Youl Kim

Sporadic Inclusion Body Myositis Correlates with Increased Expression and Cross-linking by Transglutaminases 1 and 2
J. Biol. Chem. 2000 275: 8703-8710. [Abstract] [Full Text] [PDF]  

Klara J. Belzar, Timothy R. Dafforn, Maurice Petitou, Robin W. Carrell, and James A. Huntington

The Effect of a Reducing-end Extension on Pentasaccharide Binding by Antithrombin
J. Biol. Chem. 2000 275: 8733-8741. [Abstract] [Full Text] [PDF]  

Gilles Ferry, Armelle Loynel, Nathalie Kucharczyk, Sophie Bertin, Marianne Rodriguez, Philippe Delagrange, Jean-Pierre Galizzi, Edgar Jacoby, Jean-Paul Volland, Daniel Lesieur, Pierre Renard, Emmanuel Canet, Jean-Luc Fauchère, and Jean A. Boutin

Substrate Specificity and Inhibition Studies of Human Serotonin N-Acetyltransferase
J. Biol. Chem. 2000 275: 8794-8805. [Abstract] [Full Text] [PDF]  

Hanjing Yang, Malgorzata M. Slupska, Ying-Fei Wei, Jennifer H. Tai, Wendy M. Luther, Yu-Rong Xia, Diana M. Shih, Ju-Huei Chiang, Claudia Baikalov, Sorel Fitz-Gibbon, Isabella T. Phan, Alexis Conrad, and Jeffrey H. Miller

Cloning and Characterization of a New Member of the Nudix Hydrolases from Human and Mouse
J. Biol. Chem. 2000 275: 8844-8853. [Abstract] [Full Text] [PDF]  

Karine Le Roch, Claude Sestier, Dominique Dorin, Norman Waters, Barbara Kappes, Debopam Chakrabarti, Laurent Meijer, and Christian Doerig

Activation of a Plasmodium falciparum cdc2-related Kinase by Heterologous p25 and Cyclin H. FUNCTIONAL CHARACTERIZATION OF A P. FALCIPARUM CYCLIN HOMOLOGUE
J. Biol. Chem. 2000 275: 8952-8958. [Abstract] [Full Text] [PDF]  

Metabolism and Bioenergetics:

Jason K. Kim, Oksana Gavrilova, Yan Chen, Marc L. Reitman, and Gerald I. Shulman

Mechanism of Insulin Resistance in A-ZIP/F-1 Fatless Mice
J. Biol. Chem. 2000 275: 8456-8460. [Abstract] [Full Text] [PDF]  

Sarah J. Field, Paul S. Dobbin, Myles R. Cheesman, Nicholas J. Watmough, Andrew J. Thomson, and David J. Richardson

Purification and Magneto-optical Spectroscopic Characterization of Cytoplasmic Membrane and Outer Membrane Multiheme c-Type Cytochromes from Shewanella frigidimarina NCIMB400
J. Biol. Chem. 2000 275: 8515-8522. [Abstract] [Full Text] [PDF]  

T. Wade Johnson, Gaozhong Shen, Boris Zybailov, Derrick Kolling, Ricardo Reategui, Steve Beauparlant, Ilya R. Vassiliev, Donald A. Bryant, A. Daniel Jones, John H. Golbeck, and Parag R. Chitnis

Recruitment of a Foreign Quinone into the A₁ Site of Photosystem I. I. GENETIC AND PHYSIOLOGICAL CHARACTERIZATION OF PHYLLOQUINONE BIOSYNTHETIC PATHWAY MUTANTS IN SYNECHOCYSTIS SP. PCC 6803
J. Biol. Chem. 2000 275: 8523-8530. [Abstract] [Full Text] [PDF]  

Boris Zybailov, Art van der Est, Stephan G. Zech, Christian Teutloff, T. Wade Johnson, Gaozhong Shen, Robert Bittl, Dietmar Stehlik, Parag R. Chitnis, and John H. Golbeck

Recruitment of a Foreign Quinone into the A₁ Site of Photosystem I. II. STRUCTURAL AND FUNCTIONAL CHARACTERIZATION OF PHYLLOQUINONE BIOSYNTHETIC PATHWAY MUTANTS BY ELECTRON PARAMAGNETIC RESONANCE AND ELECTRON-NUCLEAR DOUBLE RESONANCE SPECTROSCOPY
J. Biol. Chem. 2000 275: 8531-8539. [Abstract] [Full Text] [PDF]  

Glycobiology and Extracellular Matrices:

Nobuko Matsushita, Nozomu Nishi, Masako Seki, Ryoji Matsumoto, Ichiro Kuwabara, Fu-Tong Liu, Yuiro Hata, Takanori Nakamura, and Mitsuomi Hirashima

Requirement of Divalent Galactoside-binding Activity of Ecalectin/Galectin-9 for Eosinophil Chemoattraction
J. Biol. Chem. 2000 275: 8355-8360. [Abstract] [Full Text] [PDF]  

Els C. M. Brinkman-Van der Linden and Ajit Varki

New Aspects of Siglec Binding Specificities, Including the Significance of Fucosylation and of the Sialyl-Tn Epitope
J. Biol. Chem. 2000 275: 8625-8632. [Abstract] [Full Text] [PDF]  

Els C. M. Brinkman-Van der Linden, Eric R. Sjoberg, Lekh Raj Juneja, Paul R. Crocker, Nissi Varki, and Ajit Varki

Loss of N-Glycolylneuraminic Acid in Human Evolution. IMPLICATIONS FOR SIALIC ACID RECOGNITION BY SIGLECS
J. Biol. Chem. 2000 275: 8633-8640. [Abstract] [Full Text] [PDF]  

Yasutada Imamura, Ian C. Scott, and Daniel S. Greenspan

The Pro-3(V) Collagen Chain. COMPLETE PRIMARY STRUCTURE, EXPRESSION DOMAINS IN ADULT AND DEVELOPING TISSUES, AND COMPARISON TO THE STRUCTURES AND EXPRESSION DOMAINS OF THE OTHER TYPES V AND XI PROCOLLAGEN CHAINS
J. Biol. Chem. 2000 275: 8749-8759. [Abstract] [Full Text] [PDF]  

Shinobu Yamauchi, Satoka Mita, Taeko Matsubara, Masakazu Fukuta, Hiroko Habuchi, Koji Kimata, and Osami Habuchi

Molecular Cloning and Expression of Chondroitin 4-Sulfotransferase
J. Biol. Chem. 2000 275: 8975-8981. [Abstract] [Full Text] [PDF]  

Christopher Sassetti, Annemieke Van Zante, and Steven D. Rosen

Identification of Endoglycan, a Member of the CD34/Podocalyxin Family of Sialomucins
J. Biol. Chem. 2000 275: 9001-9010. [Abstract] [Full Text] [PDF]  

Lipids and Lipoproteins:

Changiz Taghibiglou, André Carpentier, Stephen C. Van Iderstine, Biao Chen, Debbie Rudy, Andrea Aiton, Gary F. Lewis, and Khosrow Adeli

Mechanisms of Hepatic Very Low Density Lipoprotein Overproduction in Insulin Resistance. EVIDENCE FOR ENHANCED LIPOPROTEIN ASSEMBLY, REDUCED INTRACELLULAR ApoB DEGRADATION, AND INCREASED MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN IN A FRUCTOSE-FED HAMSTER MODEL
J. Biol. Chem. 2000 275: 8416-8425. [Abstract] [Full Text] [PDF]  

Patrick C. N. Rensen, Miek C. Jong, Leonie C. van Vark, Hans van der Boom, Wendy L. Hendriks, Theo J. C. van Berkel, Erik A. L. Biessen, and Louis M. Havekes

Apolipoprotein E Is Resistant to Intracellular Degradation in Vitro and in Vivo. EVIDENCE FOR RETROENDOCYTOSIS
J. Biol. Chem. 2000 275: 8564-8571. [Abstract] [Full Text] [PDF]  

Moira A. Clay, Diana H. Pyle, Kerry-Anne Rye, and Philip J. Barter

Formation of Spherical, Reconstituted High Density Lipoproteins Containing Both Apolipoproteins A-I and A-II Is Mediated by Lecithin:Cholesterol Acyltransferase
J. Biol. Chem. 2000 275: 9019-9025. [Abstract] [Full Text] [PDF]  

Membrane Transport Structure Function and Biogenesis:

Shinji Asano, Keiko Kawada, Tohru Kimura, Alexander V. Grishin, Michael J. Caplan, and Noriaki Takeguchi

The Roles of Carbohydrate Chains of the -Subunit on the Functional Expression of Gastric H⁺,K⁺-ATPase
J. Biol. Chem. 2000 275: 8324-8330. [Abstract] [Full Text] [PDF]  

Ed Hurt, Katja Sträßer, Alexandra Segref, Susanne Bailer, Nick Schlaich, Carlo Presutti, David Tollervey, and Ralf Jansen

Mex67p Mediates Nuclear Export of a Variety of RNA Polymerase II Transcripts
J. Biol. Chem. 2000 275: 8361-8368. [Abstract] [Full Text] [PDF]  

Jeffrey L. Ward, Azeem Sherali, Zhi-Ping Mo, and Chung-Ming Tse

Kinetic and Pharmacological Properties of Cloned Human Equilibrative Nucleoside Transporters, ENT1 and ENT2, Stably Expressed in Nucleoside Transporter-deficient PK15 Cells. ENT2 EXHIBITS A LOW AFFINITY FOR GUANOSINE AND CYTIDINE BUT A HIGH AFFINITY FOR INOSINE
J. Biol. Chem. 2000 275: 8375-8381. [Abstract] [Full Text] [PDF]  

Leonora F. Ciufo and Alan Boyd

Identification of a Lumenal Sequence Specifying the Assembly of Emp24p into p24 Complexes in the Yeast Secretory Pathway
J. Biol. Chem. 2000 275: 8382-8388. [Abstract] [Full Text] [PDF]  

Kentaro Hanada, Tomoko Hara, and Masahiro Nishijima

Purification of the Serine Palmitoyltransferase Complex Responsible for Sphingoid Base Synthesis by Using Affinity Peptide Chromatography Techniques
J. Biol. Chem. 2000 275: 8409-8415. [Abstract] [Full Text] [PDF]  

Ruofan Jiang, Baochong Gao, Kondury Prasad, Lois E. Greene, and Evan Eisenberg

Hsc70 Chaperones Clathrin and Primes It to Interact with Vesicle Membranes
J. Biol. Chem. 2000 275: 8439-8447. [Abstract] [Full Text] [PDF]  

Shaohu Sheng, Jinqing Li, Kathleen A. McNulty, Daniel Avery, and Thomas R. Kleyman

Characterization of the Selectivity Filter of the Epithelial Sodium Channel
J. Biol. Chem. 2000 275: 8572-8581. [Abstract] [Full Text] [PDF]  

Jorgen A. Mould, Hui-Chun Li, Christine S. Dudlak, James D. Lear, Andrew Pekosz, Robert A. Lamb, and Lawrence H. Pinto

Mechanism for Proton Conduction of the M₂ Ion Channel of Influenza A Virus
J. Biol. Chem. 2000 275: 8592-8599. [Abstract] [Full Text] [PDF]  

Yoichiro Abe, Kazuhisa Nakayama, Akihiro Yamanaka, Takeshi Sakurai, and Katsutoshi Goto

Subtype-specific Trafficking of Endothelin Receptors
J. Biol. Chem. 2000 275: 8664-8671. [Abstract] [Full Text] [PDF]  

Takao Toyomura, Toshihiko Oka, Chie Yamaguchi, Yoh Wada, and Masamitsu Futai

Three Subunit a Isoforms of Mouse Vacuolar H⁺-ATPase. PREFERENTIAL EXPRESSION OF THE a3 ISOFORM DURING OSTEOCLAST DIFFERENTIATION
J. Biol. Chem. 2000 275: 8760-8765. [Abstract] [Full Text] [PDF]  

Zhongming Zhang, Zonglie Hong, and Desh Pal S. Verma

Phragmoplastin Polymerizes into Spiral Coiled Structures via Intermolecular Interaction of Two Self-assembly Domains
J. Biol. Chem. 2000 275: 8779-8784. [Abstract] [Full Text] [PDF]  

Jason D. Hoffert, Virginia Leitch, Peter Agre, and Landon S. King

Hypertonic Induction of Aquaporin-5 Expression through an ERK-dependent Pathway
J. Biol. Chem. 2000 275: 9070-9077. [Abstract] [Full Text] [PDF]  

Mechanisms Of Signal Transduction:

Martijn Rep, Marcus Krantz, Johan M. Thevelein, and Stefan Hohmann

The Transcriptional Response of Saccharomyces cerevisiae to Osmotic Shock. Hot1p AND Msn2p/Msn4p ARE REQUIRED FOR THE INDUCTION OF SUBSETS OF HIGH OSMOLARITY GLYCEROL PATHWAY-DEPENDENT GENES
J. Biol. Chem. 2000 275: 8290-8300. [Abstract] [Full Text] [PDF] Supplemental Material  

Luigia Santella, Keiichiro Kyozuka, Armando A. Genazzani, Laura De Riso, and Ernesto Carafoli

Nicotinic Acid Adenine Dinucleotide Phosphate-induced Ca²⁺ Release. INTERACTIONS AMONG DISTINCT Ca²⁺ MOBILIZING MECHANISMS IN STARFISH OOCYTES
J. Biol. Chem. 2000 275: 8301-8306. [Abstract] [Full Text] [PDF]  

Egbert Flory, Manfred Kunz, Carsten Scheller, Christian Jassoy, Roland Stauber, Ulf R. Rapp, and Stephan Ludwig

Influenza Virus-induced NF-B-dependent Gene Expression Is Mediated by Overexpression of Viral Proteins and Involves Oxidative Radicals and Activation of IB Kinase
J. Biol. Chem. 2000 275: 8307-8314. [Abstract] [Full Text] [PDF]  

Jaap J. Van Hellemond, Philippe Neuville, Ralph T. Schwarz, Keith R. Matthews, and Jeremy C. Mottram

Isolation of Trypanosoma brucei CYC2 and CYC3 Cyclin Genes by Rescue of a Yeast G₁ Cyclin Mutant. FUNCTIONAL CHARACTERIZATION OF CYC2
J. Biol. Chem. 2000 275: 8315-8323. [Abstract] [Full Text] [PDF]  

Kohichi Kawahara, Tsuyoshi Morishita, Tsutomu Nakamura, Fumihiko Hamada, Kumao Toyoshima, and Tetsu Akiyama

Down-regulation of -Catenin by the Colorectal Tumor Suppressor APC Requires Association with Axin and -Catenin
J. Biol. Chem. 2000 275: 8369-8374. [Abstract] [Full Text] [PDF]  

Hua Tang, Zhizhuang Joe Zhao, Erwin J. Landon, and Tadashi Inagami

Regulation of Calcium-sensitive Tyrosine Kinase Pyk2 by Angiotensin II in Endothelial Cells. ROLES OF Yes TYROSINE KINASE AND TYROSINE PHOSPHATASE SHP-2
J. Biol. Chem. 2000 275: 8389-8396. [Abstract] [Full Text] [PDF]  

Ralph Schaloske, Christina Schlatterer, and Dieter Malchow

A Xestospongin C-sensitive Ca²⁺ Store Is Required for cAMP-induced Ca²⁺ Influx and cAMP Oscillations in Dictyostelium
J. Biol. Chem. 2000 275: 8404-8408. [Abstract] [Full Text] [PDF]  

Mary A. Benedict, Yuanming Hu, Naohiro Inohara, and Gabriel Núñez

Expression and Functional Analysis of Apaf-1 Isoforms. EXTRA WD-40 REPEAT IS REQUIRED FOR CYTOCHROME c BINDING AND REGULATED ACTIVATION OF PROCASPASE-9
J. Biol. Chem. 2000 275: 8461-8468. [Abstract] [Full Text] [PDF]  

Xiao-qing Gan, Ji-yong Wang, Qi-heng Yang, Zhong Li, Feng Liu, Gang Pei, and Lin Li

Interaction between the Conserved Region in the C-terminal Domain of GRK2 and Rhodopsin Is Necessary for GRK2 to Catalyze Receptor Phosphorylation
J. Biol. Chem. 2000 275: 8469-8474. [Abstract] [Full Text] [PDF]  

Franco Taverna, Zhi-gang Xiong, Lidia Brandes, John C. Roder, Michael W. Salter, and John F. MacDonald

The Lurcher Mutation of an -Amino-3-hydroxy-5-methyl- 4-isoxazolepropionic Acid Receptor Subunit Enhances Potency of Glutamate and Converts an Antagonist to an Agonist
J. Biol. Chem. 2000 275: 8475-8479. [Abstract] [Full Text] [PDF]  

Hee-Sae Park, Sung-Ho Huh, Youngho Kim, Jaekyung Shim, Seung-Hoon Lee, Il-Seon Park, Yong-Keun Jung, Ick Young Kim, and Eui-Ju Choi

Selenite Negatively Regulates Caspase-3 through a Redox Mechanism
J. Biol. Chem. 2000 275: 8487-8491. [Abstract] [Full Text] [PDF]  

Bhawanjit K. Brar, Anna K. Jonassen, Anastasis Stephanou, Giorgia Santilli, Julia Railson, Richard A. Knight, Derek M. Yellon, and David S. Latchman

Urocortin Protects against Ischemic and Reperfusion Injury via a MAPK-dependent Pathway
J. Biol. Chem. 2000 275: 8508-8514. [Abstract] [Full Text] [PDF]  

Asok Mukhopadhyay, Sunil K. Manna, and Bharat B. Aggarwal

Pervanadate-induced Nuclear Factor-B Activation Requires Tyrosine Phosphorylation and Degradation of IB. COMPARISON WITH TUMOR NECROSIS FACTOR-
J. Biol. Chem. 2000 275: 8549-8555. [Abstract] [Full Text] [PDF]  

Brian L. Gerhardstein, Tianyan Gao, Moritz Bünemann, Tipu S. Puri, Adam Adair, Hong Ma, and M. Marlene Hosey

Proteolytic Processing of the C Terminus of the _1C Subunit of L-type Calcium Channels and the Role of a Proline-rich Domain in Membrane Tethering of Proteolytic Fragments
J. Biol. Chem. 2000 275: 8556-8563. [Abstract] [Full Text] [PDF]  

Hao-Chien Wang, Mark D. Zentner, Hong-Tao Deng, Kwang-Jin Kim, Reen Wu, Pan-Chyr Yang, and David K. Ann

Oxidative Stress Disrupts Glucocorticoid Hormone-dependent Transcription of the Amiloride-sensitive Epithelial Sodium Channel -Subunit in Lung Epithelial Cells through ERK-dependent and Thioredoxin-sensitive Pathways
J. Biol. Chem. 2000 275: 8600-8609. [Abstract] [Full Text] [PDF]  

Kotohiko Kimura and Edward P. Gelmann

Tumor Necrosis Factor- and Fas Activate Complementary Fas-associated Death Domain-dependent Pathways That Enhance Apoptosis Induced by -Irradiation
J. Biol. Chem. 2000 275: 8610-8617. [Abstract] [Full Text] [PDF]  

Varpu Kainulainen, Maria Sundvall, Jorma A. Määttä, Eric Santiestevan, Michael Klagsbrun, and Klaus Elenius

A Natural ErbB4 Isoform That Does Not Activate Phosphoinositide 3-Kinase Mediates Proliferation but Not Survival or Chemotaxis
J. Biol. Chem. 2000 275: 8641-8649. [Abstract] [Full Text] [PDF]  

Carsten Grullich, M. Cameron Sullards, Zvi Fuks, Alfred H. Merrill, Jr., and Richard Kolesnick

CD95(Fas/APO-1) Signals Ceramide Generation Independent of the Effector Stage of Apoptosis
J. Biol. Chem. 2000 275: 8650-8656. [Abstract] [Full Text] [PDF]  

Riting Liu, Wei Li, Norman J. Karin, Joel J. Bergh, Karen Adler-Storthz, and Mary C. Farach-Carson

Ribozyme Ablation Demonstrates That the Cardiac Subtype of the Voltage-sensitive Calcium Channel Is the Molecular Transducer of 1,25-Dihydroxyvitamin D₃-stimulated Calcium Influx in Osteoblastic Cells
J. Biol. Chem. 2000 275: 8711-8718. [Abstract] [Full Text] [PDF]  

Beverly Rothermel, Rick B. Vega, John Yang, Hai Wu, Rhonda Bassel-Duby, and R. Sanders Williams

A Protein Encoded within the Down Syndrome Critical Region Is Enriched in Striated Muscles and Inhibits Calcineurin Signaling
J. Biol. Chem. 2000 275: 8719-8725. [Abstract] [Full Text] [PDF]  

Masahiko Watabe, Hideaki Kakeya, Rie Onose, and Hiroyuki Osada

Activation of MST/Krs and c-Jun N-terminal Kinases by Different Signaling Pathways during Cytotrienin A-induced Apoptosis
J. Biol. Chem. 2000 275: 8766-8771. [Abstract] [Full Text] [PDF]  

Minji Jo, Donna Beer Stolz, James E. Esplen, Kenneth Dorko, George K. Michalopoulos, and Stephen C. Strom

Cross-talk between Epidermal Growth Factor Receptor and c-Met Signal Pathways in Transformed Cells
J. Biol. Chem. 2000 275: 8806-8811. [Abstract] [Full Text] [PDF]  

Luzheng Xue, James H. Murray, and Aviva M. Tolkovsky

The Ras/Phosphatidylinositol 3-Kinase and Ras/ERK Pathways Function as Independent Survival Modules Each of Which Inhibits a Distinct Apoptotic Signaling Pathway in Sympathetic Neurons
J. Biol. Chem. 2000 275: 8817-8824. [Abstract] [Full Text] [PDF]  

Lee A. Denson, Kathryn L. Auld, Dagmar S. Schiek, Mitchell H. McClure, David J. Mangelsdorf, and Saul J. Karpen

Interleukin-1 Suppresses Retinoid Transactivation of Two Hepatic Transporter Genes Involved in Bile Formation
J. Biol. Chem. 2000 275: 8835-8843. [Abstract] [Full Text] [PDF]  

Scott Stewart and Kun-Liang Guan

The Dominant Negative Ras Mutant, N17Ras, Can Inhibit Signaling Independently of Blocking Ras Activation
J. Biol. Chem. 2000 275: 8854-8862. [Abstract] [Full Text] [PDF]  

Yuzhi Chen, Donna L. McPhie, Joseph Hirschberg, and Rachael L. Neve

The Amyloid Precursor Protein-binding Protein APP-BP1 Drives the Cell Cycle through the S-M Checkpoint and Causes Apoptosis in Neurons
J. Biol. Chem. 2000 275: 8929-8935. [Abstract] [Full Text] [PDF]  

Maria Teresa Sommerfeld, Rüdiger Schweigreiter, Yves-Alain Barde, and Edmund Hoppe

Down-regulation of the Neurotrophin Receptor TrkB following Ligand Binding. EVIDENCE FOR AN INVOLVEMENT OF THE PROTEASOME AND DIFFERENTIAL REGULATION OF TrkA AND TrkB
J. Biol. Chem. 2000 275: 8982-8990. [Abstract] [Full Text] [PDF]  

Guangyu Wu, Galina S. Bogatkevich, Yurii V. Mukhin, Jeffrey L. Benovic, John D. Hildebrandt, and Stephen M. Lanier

Identification of G Binding Sites in the Third Intracellular Loop of the M₃-muscarinic Receptor and Their Role in Receptor Regulation
J. Biol. Chem. 2000 275: 9026-9034. [Abstract] [Full Text] [PDF]  

Vincent Aguirre, Tohru Uchida, Lynne Yenush, Roger Davis, and Morris F. White

The c-Jun NH₂-terminal Kinase Promotes Insulin Resistance during Association with Insulin Receptor Substrate-1 and Phosphorylation of Ser³⁰⁷
J. Biol. Chem. 2000 275: 9047-9054. [Abstract] [Full Text] [PDF]  

David K. Perry, Jill Carton, Amit K. Shah, Filmore Meredith, David J. Uhlinger, and Yusuf A. Hannun

Serine Palmitoyltransferase Regulates de Novo Ceramide Generation during Etoposide-induced Apoptosis
J. Biol. Chem. 2000 275: 9078-9084. [Abstract] [Full Text] [PDF]  

Molecular Basis Of Cell and Developmental Biology:

Yasushi Shibata, Takashi Iwamatsu, Yuichi Oba, Daisuke Kobayashi, Minoru Tanaka, Yoshitaka Nagahama, Norio Suzuki, and Michiyasu Yoshikuni

Identification and cDNA Cloning of Alveolin, an Extracellular Metalloproteinase, Which Induces Chorion Hardening of Medaka (Oryzias latipes) Eggs upon Fertilization
J. Biol. Chem. 2000 275: 8349-8354. [Abstract] [Full Text] [PDF]  

Tesu Lin, Laurent Genestier, Michael J. Pinkoski, Arturo Castro, Shelby Nicholas, Rona Mogil, Francois Paris, Zvi Fuks, Edward H. Schuchman, Richard N. Kolesnick, and Douglas R. Green

Role of Acidic Sphingomyelinase in Fas/CD95-mediated Cell Death
J. Biol. Chem. 2000 275: 8657-8663. [Abstract] [Full Text] [PDF]  

Hirayuki Enomoto, Motomi Enomoto-Iwamoto, Masahiro Iwamoto, Shintaro Nomura, Miki Himeno, Yukihiko Kitamura, Tadamitsu Kishimoto, and Toshihisa Komori

Cbfa1 Is a Positive Regulatory Factor in Chondrocyte Maturation
J. Biol. Chem. 2000 275: 8695-8702. [Abstract] [Full Text] [PDF]  

Yasushi Kobayashi, Akito Kume, Mei Li, Manabu Doyu, Mami Hata, Kenzo Ohtsuka, and Gen Sobue

Chaperones Hsp70 and Hsp40 Suppress Aggregate Formation and Apoptosis in Cultured Neuronal Cells Expressing Truncated Androgen Receptor Protein with Expanded Polyglutamine Tract
J. Biol. Chem. 2000 275: 8772-8778. [Abstract] [Full Text] [PDF]  

Pamela J. McLean, Hibiki Kawamata, Scott Ribich, and Bradley T. Hyman

Membrane Association and Protein Conformation of -Synuclein in Intact Neurons. EFFECT OF PARKINSON'S DISEASE-LINKED MUTATIONS
J. Biol. Chem. 2000 275: 8812-8816. [Abstract] [Full Text] [PDF]  

Norbert Bakalara, Xavier Santarelli, Charles Davis, and Théo Baltz

Purification, Cloning, and Characterization of an Acidic Ectoprotein Phosphatase Differentially Expressed in the Infectious Bloodstream Form of Trypanosoma brucei
J. Biol. Chem. 2000 275: 8863-8871. [Abstract] [Full Text] [PDF]  

Tadakazu Kondo, Tomoko Matsuda, Masaro Tashima, Hisanori Umehara, Naochika Domae, Kazunao Yokoyama, Takashi Uchiyama, and Toshiro Okazaki

Suppression of Heat Shock Protein-70 by Ceramide in Heat Shock-induced HL-60 Cell Apoptosis
J. Biol. Chem. 2000 275: 8872-8879. [Abstract] [Full Text] [PDF]  

Isabelle Groulx, Marie-Eve Bonicalzi, and Stephen Lee

Ran-mediated Nuclear Export of the von Hippel-Lindau Tumor Suppressor Protein Occurs Independently of Its Assembly with Cullin-2
J. Biol. Chem. 2000 275: 8991-9000. [Abstract] [Full Text] [PDF]  

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