JBC -- Table of Contents (Apr 7 2000, 275, (14))

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Accelerated Publications:

Lynn E. Bretscher, Richele L. Abel, and Ronald T. Raines: A Ribonuclease A Variant with Low Catalytic Activity but High Cytotoxicity
J. Biol. Chem. 2000 275: 9893-9896. [Abstract] [Full Text] [PDF]

Toshio Kitazawa, Masumi Eto, Terence P. Woodsome, and David L. Brautigan: Agonists Trigger G Protein-mediated Activation of the CPI-17 Inhibitor Phosphoprotein of Myosin Light Chain Phosphatase to Enhance Vascular Smooth Muscle Contractility
J. Biol. Chem. 2000 275: 9897-9900. [Abstract] [Full Text] [PDF]

Ruth McMahon, Madeline Murphy, Michael Clarkson, Maarten Taal, Harald S. Mackenzie, Catherine Godson, Finian Martin, and Hugh R. Brady: IHG-2, a Mesangial Cell Gene Induced by High Glucose, Is Human gremlin. REGULATION BY EXTRACELLULAR GLUCOSE CONCENTRATION, CYCLIC MECHANICAL STRAIN, AND TRANSFORMING GROWTH FACTOR- $beta$ 1
J. Biol. Chem. 2000 275: 9901-9904. [Abstract] [Full Text] [PDF]

DNA: Replication Repair and Recombination:

Olga M. Sidorkina and Jacques Laval: Role of the N-terminal Proline Residue in the Catalytic Activities of the Escherichia coli Fpg Protein
J. Biol. Chem. 2000 275: 9924-9929. [Abstract] [Full Text] [PDF]

Garry W. Blakely, Anne O. Davidson, and David J. Sherratt: Sequential Strand Exchange by XerC and XerD during Site-specific Recombination at dif
J. Biol. Chem. 2000 275: 9930-9936. [Abstract] [Full Text] [PDF]

Michel M. Ouellette, Martha Liao, Brittney-Shea Herbert, Mari Johnson, Shawn E. Holt, Heidi S. Liss, Jerry W. Shay, and Woodring E. Wright: Subsenescent Telomere Lengths in Fibroblasts Immortalized by Limiting Amounts of Telomerase
J. Biol. Chem. 2000 275: 10072-10076. [Abstract] [Full Text] [PDF]

Hirohumi Arakawa, Rohana Ahmad, Mancef Naoui, and Heidar-Ali Tajmir-Riahi: A Comparative Study of Calf Thymus DNA Binding to Cr(III) and Cr(VI) Ions. EVIDENCE FOR THE GUANINE N-7-CHROMIUM-PHOSPHATE CHELATE FORMATION
J. Biol. Chem. 2000 275: 10150-10153. [Abstract] [Full Text] [PDF]

Leesa J. Deterding, Rajendra Prasad, Gregory P. Mullen, Samuel H. Wilson, and Kenneth B. Tomer: Mapping of the 5'-2-Deoxyribose-5-phosphate Lyase Active Site in DNA Polymerase $beta$ by Mass Spectrometry
J. Biol. Chem. 2000 275: 10463-10471. [Abstract] [Full Text] [PDF]

Hirotake Kitaura, Minako Shinshi, Yasuko Uchikoshi, Takashi Ono, Toshiki Tsurimoto, Hiroshi Yoshikawa, Sanae M. M. Iguchi-Ariga, and Hiroyoshi Ariga: Reciprocal Regulation via Protein-Protein Interaction between c-Myc and p21^{cip1/waf1/sdi1} in DNA Replication and Transcription
J. Biol. Chem. 2000 275: 10477-10483. [Abstract] [Full Text] [PDF]

Samson Tom, Leigh A. Henricksen, and Robert A. Bambara: Mechanism Whereby Proliferating Cell Nuclear Antigen Stimulates Flap Endonuclease 1
J. Biol. Chem. 2000 275: 10498-10505. [Abstract] [Full Text] [PDF]

Genes: Structure and Regulation:

David J. Mancuso, Christopher M. Jenkins, and Richard W. Gross: The Genomic Organization, Complete mRNA Sequence, Cloning, and Expression of a Novel Human Intracellular Membrane-associated Calcium-independent Phospholipase A₂
J. Biol. Chem. 2000 275: 9937-9945. [Abstract] [Full Text] [PDF]

Gabrielle Mengus, Yann-Gaël Gangloff, Lucie Carré, Anne-Claire Lavigne, and Irwin Davidson: The Human Transcription Factor IID Subunit Human TATA-binding Protein-associated Factor 28 Interacts in a Ligand-reversible Manner with the Vitamin D₃ and Thyroid Hormone Receptors
J. Biol. Chem. 2000 275: 10064-10071. [Abstract] [Full Text] [PDF]

Yang Soo Moon, Maria-Jesus Latasa, Kee-Hong Kim, Dong Wang, and Hei Sook Sul: Two 5'-Regions Are Required for Nutritional and Insulin Regulation of the Fatty-acid Synthase Promoter in Transgenic Mice
J. Biol. Chem. 2000 275: 10121-10127. [Abstract] [Full Text] [PDF]

Jocelyn D. Weissman, T. Kevin Howcroft, and Dinah S. Singer: TAF_II250-independent Transcription Can Be Conferred on a TAF_II250-dependent Basal Promoter by Upstream Activators
J. Biol. Chem. 2000 275: 10160-10167. [Abstract] [Full Text] [PDF]

Volkher Scharnhorst, Patrick Dekker, Alex J. van der Eb, and Aart G. Jochemsen: Physical Interaction between Wilms Tumor 1 and p73 Proteins Modulates Their Functions
J. Biol. Chem. 2000 275: 10202-10211. [Abstract] [Full Text] [PDF]

Javier M. Di Noia, Iván D'Orso, Daniel O. Sánchez, and Alberto C. C. Frasch: AU-rich Elements in the 3'-Untranslated Region of a New Mucin-type Gene Family of Trypanosoma cruzi Confers mRNA Instability and Modulates Translation Efficiency
J. Biol. Chem. 2000 275: 10218-10227. [Abstract] [Full Text] [PDF]

Seetha R. Thotakura, Narayanan Karthikeyan, Taryn Smith, Kai Liu, and Anne George: Cloning and Characterization of Rat Dentin Matrix Protein 1 (DMP1) Gene and Its 5'-Upstream Region
J. Biol. Chem. 2000 275: 10272-10277. [Abstract] [Full Text] [PDF]

Sanjay Kumar, Peter C. McDonnell, Ruth Lehr, Lauren Tierney, Maritsa N. Tzimas, Don E. Griswold, Elizabeth A. Capper, Ruth Tal-Singer, Grace I. Wells, Michael L. Doyle, and Peter R. Young: Identification and Initial Characterization of Four Novel Members of the Interleukin-1 Family
J. Biol. Chem. 2000 275: 10308-10314. [Abstract] [Full Text] [PDF]

Royce Mohan, Jeremy Sivak, Paul Ashton, Laoti A. Russo, Bao Q. Pham, Niro Kasahara, Michael B. Raizman, and M. Elizabeth Fini: Curcuminoids Inhibit the Angiogenic Response Stimulated by Fibroblast Growth Factor-2, Including Expression of Matrix Metalloproteinase Gelatinase B
J. Biol. Chem. 2000 275: 10405-10412. [Abstract] [Full Text] [PDF]

Li Zhao, Michelle A. Cissell, Eva Henderson, Roger Colbran, and Roland Stein: The RIPE3b1 Activator of the Insulin Gene Is Composed of a Protein(s) of Approximately 43 kDa, Whose DNA Binding Activity Is Inhibited by Protein Phosphatase Treatment
J. Biol. Chem. 2000 275: 10532-10537. [Abstract] [Full Text] [PDF]

Patrice Riou, Françoise Bex, and Louis Gazzolo: The Human T Cell Leukemia/Lymphotropic Virus Type 1 Tax Protein Represses MyoD-dependent Transcription by Inhibiting MyoD-binding to the KIX Domain of p300. A POTENTIAL MECHANISM FOR Tax-MEDIATED REPRESSION OF THE TRANSCRIPTIONAL ACTIVITY OF BASIC HELIX-LOOP-HELIX FACTORS
J. Biol. Chem. 2000 275: 10551-10560. [Abstract] [Full Text] [PDF]

Emanuela Moroni, Tiziana Mastrangelo, Riccardo Razzini, Linda Cairns, Paolo Moi, Sergio Ottolenghi, and Barbara Giglioni: Regulation of Mouse p45 NF-E2 Transcription by an Erythroid-specific GATA-dependent Intronic Alternative Promoter
J. Biol. Chem. 2000 275: 10567-10576. [Abstract] [Full Text] [PDF]

Bryan A. Laffitte, Heidi Rachelle Kast, Catherine M. Nguyen, Ann Marie Zavacki, David D. Moore, and Peter A. Edwards: Identification of the DNA Binding Specificity and Potential Target Genes for the Farnesoid X-activated Receptor
J. Biol. Chem. 2000 275: 10638-10647. [Abstract] [Full Text] [PDF]

Maria Neve Cervellera and Arturo Sala: Poly(ADP-ribose) Polymerase Is a B-MYB Coactivator
J. Biol. Chem. 2000 275: 10692-10696. [Abstract] [Full Text] [PDF]

RNA: Structure Metabolism and Catalysis:

Ahmed F. Kilani, Phong Trang, Stephen Jo, Amy Hsu, Joseph Kim, Edward Nepomuceno, Kwa Liou, and Fenyong Liu: RNase P Ribozymes Selected in Vitro to Cleave a Viral mRNA Effectively Inhibit Its Expression in Cell Culture
J. Biol. Chem. 2000 275: 10611-10622. [Abstract] [Full Text] [PDF]

Protein Synthesis Post-Translation Modification and Degradation:

Richard J. S. Baerends, Klaas Nico Faber, Anita M. Kram, Jan A. K. W. Kiel, Ida J. van der Klei, and Marten Veenhuis: A Stretch of Positively Charged Amino Acids at the N Terminus of Hansenula polymorpha Pex3p Is Involved in Incorporation of the Protein into the Peroxisomal Membrane
J. Biol. Chem. 2000 275: 9986-9995. [Abstract] [Full Text] [PDF]

Aarnoud van der Spoel, Erik Bonten, and Alessandra d'Azzo: Processing of Lysosomal $beta$ -Galactosidase. THE C-TERMINAL PRECURSOR FRAGMENT IS AN ESSENTIAL DOMAIN OF THE MATURE ENZYME
J. Biol. Chem. 2000 275: 10035-10040. [Abstract] [Full Text] [PDF]

Carlos Rio, Joseph D. Buxbaum, Jacques J. Peschon, and Gabriel Corfas: Tumor Necrosis Factor- $alpha$ -converting Enzyme Is Required for Cleavage of erbB4/HER4
J. Biol. Chem. 2000 275: 10379-10387. [Abstract] [Full Text] [PDF]

Brett D. Keiper, Barry J. Lamphear, Atul M. Deshpande, Marzena Jankowska-Anyszka, Eric J. Aamodt, Thomas Blumenthal, and Robert E. Rhoads: Functional Characterization of Five eIF4E Isoforms in Caenorhabditis elegans
J. Biol. Chem. 2000 275: 10590-10596. [Abstract] [Full Text] [PDF]

Genomics Proteomics and Bioinformatics:

Donald L. McKenzie, Kai Y. Kwok, and Kevin G. Rice: A Potent New Class of Reductively Activated Peptide Gene Delivery Agents
J. Biol. Chem. 2000 275: 9970-9977. [Abstract] [Full Text] [PDF]

Protein Structure and Folding:

Sergei Maliartchouk, Thomas Debeir, Natalia Beglova, A. Claudio Cuello, Kalle Gehring, and H. Uri Saragovi: Genuine Monovalent Ligands of TrkA Nerve Growth Factor Receptors Reveal a Novel Pharmacological Mechanism of Action
J. Biol. Chem. 2000 275: 9946-9956. [Abstract] [Full Text] [PDF]

Tien-sheng Huang, Haiyao Wang, So Young Lee, Mats W. Johansson, Kenneth Söderhäll, and Lage Cerenius: A Cell Adhesion Protein from the Crayfish Pacifastacus leniusculus, a Serine Proteinase Homologue Similar to Drosophila Masquerade
J. Biol. Chem. 2000 275: 9996-10001. [Abstract] [Full Text] [PDF]

Leanne G. Laajoki, Geoffrey L. Francis, John C. Wallace, John A. Carver, and Max A. Keniry: Solution Structure and Backbone Dynamics of Long-[Arg³]insulin-like Growth Factor-I
J. Biol. Chem. 2000 275: 10009-10015. [Abstract] [Full Text] [PDF]

Scott E. Chesla, Ping Li, Shanmugam Nagarajan, Periasamy Selvaraj, and Cheng Zhu: The Membrane Anchor Influences Ligand Binding Two-dimensional Kinetic Rates and Three-dimensional Affinity of Fc $gamma$ RIII (CD16)
J. Biol. Chem. 2000 275: 10235-10246. [Abstract] [Full Text] [PDF]

María A. Urbaneja, Connor F. McGrath, Bradley P. Kane, Louis E. Henderson, and José R. Casas-Finet: Nucleic Acid Binding Properties of the Simian Immunodeficiency Virus Nucleocapsid Protein NCp8
J. Biol. Chem. 2000 275: 10394-10404. [Abstract] [Full Text] [PDF]

Gun Stenberg, Beatrice Dragani, Roberta Cocco, Bengt Mannervik, and Antonio Aceto: A Conserved "Hydrophobic Staple Motif" Plays a Crucial Role in the Refolding of Human Glutathione Transferase P1-1
J. Biol. Chem. 2000 275: 10421-10428. [Abstract] [Full Text] [PDF]

Isabelle Batisson and Maurice Der Vartanian: Extracellular DsbA-insensitive Folding of Escherichia coli Heat-stable Enterotoxin STa in Vitro
J. Biol. Chem. 2000 275: 10582-10589. [Abstract] [Full Text] [PDF]

Jérôme Célérier, Georg Schmid, Jean-Pierre Le Caer, Anne-Paule Gimenez-Roqueplo, Daniel Bur, Arno Friedlein, Hanno Langen, Pierre Corvol, and Xavier Jeunemaitre: Characterization of a Human Angiotensinogen Cleaved in Its Reactive Center Loop by a Proteolytic Activity from Chinese Hamster Ovary Cells
J. Biol. Chem. 2000 275: 10648-10654. [Abstract] [Full Text] [PDF]

Yukio Kimata, Hironori Higashio, and Kenji Kohno: Impaired Proteasome Function Rescues Thermosensitivity of Yeast Cells Lacking the Coatomer Subunit $epsilon$ -COP
J. Biol. Chem. 2000 275: 10655-10660. [Abstract] [Full Text] [PDF]

Enzyme Catalysis and Regulation:

Rohana Yusof, Stephen Clum, Mary Wetzel, H. M. Krishna Murthy, and R. Padmanabhan: Purified NS2B/NS3 Serine Protease of Dengue Virus Type 2 Exhibits Cofactor NS2B Dependence for Cleavage of Substrates with Dibasic Amino Acids in Vitro
J. Biol. Chem. 2000 275: 9963-9969. [Abstract] [Full Text] [PDF]

Bruno Bühler, Andreas Schmid, Bernhard Hauer, and Bernard Witholt: Xylene Monooxygenase Catalyzes the Multistep Oxygenation of Toluene and Pseudocumene to Corresponding Alcohols, Aldehydes, and Acids in Escherichia coli JM101
J. Biol. Chem. 2000 275: 10085-10092. [Abstract] [Full Text] [PDF]

Ronald J. Stewart, James C. Fredenburgh, Beverly A. Leslie, Bruce A. Keyt, Janice A. Rischke, and Jeffrey I. Weitz: Identification of the Mechanism Responsible for the Increased Fibrin Specificity of TNK-Tissue Plasminogen Activator Relative to Tissue Plasminogen Activator
J. Biol. Chem. 2000 275: 10112-10120. [Abstract] [Full Text] [PDF]

Lars Fogh Iversen, Henrik Sune Andersen, Sven Branner, Steen B. Mortensen, Günther H. Peters, Kjeld Norris, Ole Hvilsted Olsen, Claus Bekker Jeppesen, Behrend F. Lundt, William Ripka, Karin Bach Møller, and Niels Peter Hundahl Møller: Structure-based Design of a Low Molecular Weight, Nonphosphorus, Nonpeptide, and Highly Selective Inhibitor of Protein-tyrosine Phosphatase 1B
J. Biol. Chem. 2000 275: 10300-10307. [Abstract] [Full Text] [PDF]

Luciano Piubelli, Alessandro Aliverti, Adrián K. Arakaki, Néstor Carrillo, Eduardo A. Ceccarelli, P. Andrew Karplus, and Giuliana Zanetti: Competition between C-terminal Tyrosine and Nicotinamide Modulates Pyridine Nucleotide Affinity and Specificity in Plant Ferredoxin-NADP⁺ Reductase
J. Biol. Chem. 2000 275: 10472-10476. [Abstract] [Full Text] [PDF]

Isabelle Landrieu, Lieven De Veylder, Jean-Sébastien Fruchart, Benoît Odaert, Peter Casteels, Daniel Portetelle, Marc Van Montagu, Dirk Inzé, and Guy Lippens: The Arabidopsis thaliana PIN1At Gene Encodes a Single-domain Phosphorylation-dependent Peptidyl Prolyl cis/trans Isomerase
J. Biol. Chem. 2000 275: 10577-10581. [Abstract] [Full Text] [PDF]

Akiko Kozaki, Koichiro Kamada, Yukio Nagano, Hiro Iguchi, and Yukiko Sasaki: Recombinant Carboxyltransferase Responsive to Redox of Pea Plastidic Acetyl-CoA Carboxylase
J. Biol. Chem. 2000 275: 10702-10708. [Abstract] [Full Text] [PDF]

Metabolism and Bioenergetics:

Wan Lee, Jiwon Ryu, Jongsik Hah, Takahiro Tsujita, and Chan Y. Jung: Association of Carboxyl Esterase with Facilitative Glucose Transporter Isoform 4 (GLUT4) Intracellular Compartments in Rat Adipocytes and Its Possible Role in Insulin-induced GLUT4 Recruitment
J. Biol. Chem. 2000 275: 10041-10046. [Abstract] [Full Text] [PDF]

Huimiao Ren and William S. Allison: Substitution of $beta$ Glu²⁰¹ in the $alpha$ ₃ $beta$ ₃ $gamma$ Subcomplex of the F₁-ATPase from the Thermophilic Bacillus PS3 Increases the Affinity of Catalytic Sites for Nucleotides
J. Biol. Chem. 2000 275: 10057-10063. [Abstract] [Full Text] [PDF]

Jean-Baptiste Martin, Tim Laussmann, Tilly Bakker-Grunwald, Günter Vogel, and Gérard Klein: neo-Inositol Polyphosphates in the Amoeba Entamoeba histolytica
J. Biol. Chem. 2000 275: 10134-10140. [Abstract] [Full Text] [PDF]

Mark Renz, Elizabeth Tomlinson, Bruce Hultgren, Nancy Levin, Qimin Gu, Richard A. Shimkets, David A. Lewin, and Timothy A. Stewart: Quantitative Expression Analysis of Genes Regulated by Both Obesity and Leptin Reveals a Regulatory Loop between Leptin and Pituitary-derived ACTH
J. Biol. Chem. 2000 275: 10429-10436. [Abstract] [Full Text] [PDF]

Tadashi Mabuchi, Yoshinobu Ichimura, Masaharu Takeda, and Michael G. Douglas: ASC1/RAS2 Suppresses the Growth Defect on Glycerol Caused by the atp1-2 Mutation in the Yeast Saccharomyces cerevisiae
J. Biol. Chem. 2000 275: 10492-10497. [Abstract] [Full Text] [PDF]

Núria de la Iglesia, Mohammed Mukhtar, Joan Seoane, Joan J. Guinovart, and Loranne Agius: The Role of the Regulatory Protein of Glucokinase in the Glucose Sensory Mechanism of the Hepatocyte
J. Biol. Chem. 2000 275: 10597-10603. [Abstract] [Full Text] [PDF]

Cheol-Won Yun, Tracy Ferea, Jared Rashford, Orly Ardon, Patrick O. Brown, David Botstein, Jerry Kaplan, and Caroline C. Philpott: Desferrioxamine-mediated Iron Uptake in Saccharomyces cerevisiae. EVIDENCE FOR TWO PATHWAYS OF IRON UPTAKE
J. Biol. Chem. 2000 275: 10709-10715. [Abstract] [Full Text] [PDF]

Glycobiology and Extracellular Matrices:

Ivo G. Boneca, Zhi-Heng Huang, Douglas A. Gage, and Alexander Tomasz: Characterization of Staphylococcus aureus Cell Wall Glycan Strands, Evidence for a New $beta$ -N-Acetylglucosaminidase Activity
J. Biol. Chem. 2000 275: 9910-9918. [Abstract] [Full Text] [PDF]

Daniel I. Simon, Ying Wei, Li Zhang, Navaneetha K. Rao, Hui Xu, Zhiping Chen, Qiumei Liu, Steven Rosenberg, and Harold A. Chapman: Identification of a Urokinase Receptor-Integrin Interaction Site. PROMISCUOUS REGULATOR OF INTEGRIN FUNCTION
J. Biol. Chem. 2000 275: 10228-10234. [Abstract] [Full Text] [PDF]

Joseph M. Vinetz, Jesus G. Valenzuela, Charles A. Specht, L. Aravind, Rebecca C. Langer, Jose M. C. Ribeiro, and David C. Kaslow: Chitinases of the Avian Malaria Parasite Plasmodium gallinaceum, a Class of Enzymes Necessary for Parasite Invasion of the Mosquito Midgut
J. Biol. Chem. 2000 275: 10331-10341. [Abstract] [Full Text] [PDF]

Ulrich K. Blaschke, Eric F. Eikenberry, David J. S. Hulmes, Hans-Joachim Galla, and Peter Bruckner: Collagen XI Nucleates Self-assembly and Limits Lateral Growth of Cartilage Fibrils
J. Biol. Chem. 2000 275: 10370-10378. [Abstract] [Full Text] [PDF]

Hanqing Mo, Harry C. Winter, and Irwin J. Goldstein: Purification and Characterization of a Neu5Ac $alpha$ 2-6Gal $beta$ 1-4Glc/GlcNAc-specific Lectin from the Fruiting Body of the Polypore Mushroom Polyporus squamosus
J. Biol. Chem. 2000 275: 10623-10629. [Abstract] [Full Text] [PDF]

Denise C. Hocking, Jane Sottile, and Kurt J. Langenbach: Stimulation of Integrin-mediated Cell Contractility by Fibronectin Polymerization
J. Biol. Chem. 2000 275: 10673-10682. [Abstract] [Full Text] [PDF]

Lipids and Lipoproteins:

Swetlana A. Boldin and Anthony H. Futerman: Up-regulation of Glucosylceramide Synthesis upon Stimulation of Axonal Growth by Basic Fibroblast Growth Factor. EVIDENCE FOR POST-TRANSLATIONAL MODIFICATION OF GLUCOSYLCERAMIDE SYNTHASE
J. Biol. Chem. 2000 275: 9905-9909. [Abstract] [Full Text] [PDF]

Jozsef I. Heller, Jan R. Crowley, Stanley L. Hazen, David M. Salvay, Peter Wagner, Subramaniam Pennathur, and Jay W. Heinecke: p-Hydroxyphenylacetaldehyde, an Aldehyde Generated by Myeloperoxidase, Modifies Phospholipid Amino Groups of Low Density Lipoprotein in Human Atherosclerotic Intima
J. Biol. Chem. 2000 275: 9957-9962. [Abstract] [Full Text] [PDF]

Uwe J. F. Tietge, Cyrille Maugeais, William Cain, David Grass, Jane M. Glick, Frederick C. de Beer, and Daniel J. Rader: Overexpression of Secretory Phospholipase A₂ Causes Rapid Catabolism and Altered Tissue Uptake of High Density Lipoprotein Cholesteryl Ester and Apolipoprotein A-I
J. Biol. Chem. 2000 275: 10077-10084. [Abstract] [Full Text] [PDF]

Pia Stillemark, Jan Borén, Maria Andersson, Thomas Larsson, Sabina Rustaeus, Karl-Anders Karlsson, and Sven-Olof Olofsson: The Assembly and Secretion of Apolipoprotein B-48-containing Very Low Density Lipoproteins in McA-RH7777 Cells
J. Biol. Chem. 2000 275: 10506-10513. [Abstract] [Full Text] [PDF]

Membrane Transport Structure Function and Biogenesis:

Paola Palestini, Marina Pitto, Gabriella Tedeschi, Anita Ferraretto, Marco Parenti, Joseph Brunner, and Massimo Masserini: Tubulin Anchoring to Glycolipid-enriched, Detergent-resistant Domains of the Neuronal Plasma Membrane
J. Biol. Chem. 2000 275: 9978-9985. [Abstract] [Full Text] [PDF]

Xianyue Ma and Kenneth Cline: Precursors Bind to Specific Sites on Thylakoid Membranes prior to Transport on the Delta pH Protein Translocation System
J. Biol. Chem. 2000 275: 10016-10022. [Abstract] [Full Text] [PDF]

Hongwen Yue, Sreenivas Devidas, and William B. Guggino: The Two Halves of CFTR Form a Dual-pore Ion Channel
J. Biol. Chem. 2000 275: 10030-10034. [Abstract] [Full Text] [PDF]

François Maingret, Amanda J. Patel, Florian Lesage, Michel Lazdunski, and Eric Honoré: Lysophospholipids Open the Two-pore Domain Mechano-gated K⁺ Channels TREK-1 and TRAAK
J. Biol. Chem. 2000 275: 10128-10133. [Abstract] [Full Text] [PDF]

Ligong Wang, Alexander Miller, and Debra A. Kendall: Signal Peptide Determinants of SecA Binding and Stimulation of ATPase Activity
J. Biol. Chem. 2000 275: 10154-10159. [Abstract] [Full Text] [PDF]

Yuk-Man Leung, Wei-Zhong Zeng, Horng-Huei Liou, Christopher R. Solaro, and Chou-Long Huang: Phosphatidylinositol 4,5-Bisphosphate and Intracellular pH Regulate the ROMK1 Potassium Channel via Separate but Interrelated Mechanisms
J. Biol. Chem. 2000 275: 10182-10189. [Abstract] [Full Text] [PDF]

Adam D. Linstedt, Stephen A. Jesch, Amy Mehta, Tina H. Lee, Rafael Garcia-Mata, David S. Nelson, and Elizabeth Sztul: Binding Relationships of Membrane Tethering Components. THE GIANTIN N TERMINUS AND THE GM130 N TERMINUS COMPETE FOR BINDING TO THE p115 C TERMINUS
J. Biol. Chem. 2000 275: 10196-10201. [Abstract] [Full Text] [PDF]

Willem Albert Rensink, Danny J. Schnell, and Peter J. Weisbeek: The Transit Sequence of Ferredoxin Contains Different Domains for Translocation across the Outer and Inner Membrane of the Chloroplast Envelope
J. Biol. Chem. 2000 275: 10265-10271. [Abstract] [Full Text] [PDF]

Jing Zhai, Albrecht G. Schmidt, Brian D. Hoit, Yoshihiro Kimura, David H. MacLennan, and Evangelia G. Kranias: Cardiac-specific Overexpression of a Superinhibitory Pentameric Phospholamban Mutant Enhances Inhibition of Cardiac Function in Vivo
J. Biol. Chem. 2000 275: 10538-10544. [Abstract] [Full Text] [PDF]

Ralf Jacob, Jocelyn R. Weiner, Stephanie Stadge, and Hassan Y. Naim: Additional N-Glycosylation and Its Impact on the Folding of Intestinal Lactase-phlorizin Hydrolase
J. Biol. Chem. 2000 275: 10630-10637. [Abstract] [Full Text] [PDF]

Nicola S. Carter, Choukri Ben Mamoun, Wei Liu, Edilene O. Silva, Scott M. Landfear, Daniel E. Goldberg, and Buddy Ullman: Isolation and Functional Characterization of the PfNT1 Nucleoside Transporter Gene from Plasmodium falciparum
J. Biol. Chem. 2000 275: 10683-10691. [Abstract] [Full Text] [PDF]

Mechanisms Of Signal Transduction:

Lorenzo Camoni, Valentina Iori, Mauro Marra, and Patrizia Aducci: Phosphorylation-dependent Interaction between Plant Plasma Membrane H⁺-ATPase and 14-3-3 Proteins
J. Biol. Chem. 2000 275: 9919-9923. [Abstract] [Full Text] [PDF]

Anastasis Stephanou, Bhawanjit K. Brar, Tiziano M. Scarabelli, Anna K. Jonassen, Derick M. Yellon, Michael S. Marber, Richard A. Knight, and David S. Latchman: Ischemia-induced STAT-1 Expression and Activation Play a Critical Role in Cardiomyocyte Apoptosis
J. Biol. Chem. 2000 275: 10002-10008. [Abstract] [Full Text] [PDF]

Franklin G. Harwood, Shailaja Kasibhatla, Istvan Petak, Reka Vernes, Douglas R. Green, and Janet A. Houghton: Regulation of FasL by NF- $kappa$ B and AP-1 in Fas-dependent Thymineless Death of Human Colon Carcinoma Cells
J. Biol. Chem. 2000 275: 10023-10029. [Abstract] [Full Text] [PDF]

Jing Xue, Xin Wang, Chandra S. Malladi, Makoto Kinoshita, Peter J. Milburn, Imre Lengyel, John A. P. Rostas, and Phillip J. Robinson: Phosphorylation of a New Brain-specific Septin, G-septin, by cGMP-dependent Protein Kinase
J. Biol. Chem. 2000 275: 10047-10056. [Abstract] [Full Text] [PDF]

Cristina M. Rondinone, Eugénia Carvalho, Tova Rahn, Vincent C. Manganiello, Eva Degerman, and Ulf P. Smith: Phosphorylation of PDE3B by Phosphatidylinositol 3-Kinase Associated with the Insulin Receptor
J. Biol. Chem. 2000 275: 10093-10098. [Abstract] [Full Text] [PDF]

Karon Abe, Kent L. Rossman, Betty Liu, Kimberly D. Ritola, Derek Chiang, Sharon L. Campbell, Keith Burridge, and Channing J. Der: Vav2 Is an Activator of Cdc42, Rac1, and RhoA
J. Biol. Chem. 2000 275: 10141-10149. [Abstract] [Full Text] [PDF]

Paschal A. Oude Weernink, Peter Schulte, Yuanjian Guo, Julia Wetzel, Mutsuki Amano, Kozo Kaibuchi, Sven Haverland, Matthias Voß, Martina Schmidt, Georg W. Mayr, and Karl H. Jakobs: Stimulation of Phosphatidylinositol-4-phosphate 5-Kinase by Rho-Kinase
J. Biol. Chem. 2000 275: 10168-10174. [Abstract] [Full Text] [PDF]

Tracy A. Shahan, William G. Sorenson, Janet Simpson, Nicholas A. Kefalides, and Daniel M. Lewis: Tyrosine Kinase Activation in Response to Fungal Spores Is Primarily Dependent on Endogenous Reactive Oxygen Production in Macrophages
J. Biol. Chem. 2000 275: 10175-10181. [Abstract] [Full Text] [PDF]

Éric Boué-Grabot, Vincent Archambault, and Philippe Séguéla: A Protein Kinase C Site Highly Conserved in P2X Subunits Controls the Desensitization Kinetics of P2X₂ ATP-gated Channels
J. Biol. Chem. 2000 275: 10190-10195. [Abstract] [Full Text] [PDF]

Iwan Beuvink, Daniel Hess, Horst Flotow, Jan Hofsteenge, Bernd Groner, and Nancy E. Hynes: Stat5a Serine Phosphorylation. SERINE 779 IS CONSTITUTIVELY PHOSPHORYLATED IN THE MAMMARY GLAND, AND SERINE 725 PHOSPHORYLATION INFLUENCES PROLACTIN-STIMULATED IN VITRO DNA BINDING ACTIVITY
J. Biol. Chem. 2000 275: 10247-10255. [Abstract] [Full Text] [PDF]

Guofeng You, Kogo Kuze, Ronald A. Kohanski, Kurt Amsler, and Scott Henderson: Regulation of mOAT-mediated Organic Anion Transport by Okadaic Acid and Protein Kinase C in LLC-PK₁ Cells
J. Biol. Chem. 2000 275: 10278-10284. [Abstract] [Full Text] [PDF]

Robert H. Weiss, Adriane Joo, and Collette Randour: p21^Waf1/Cip1 Is an Assembly Factor Required for Platelet-derived Growth Factor-induced Vascular Smooth Muscle Cell Proliferation
J. Biol. Chem. 2000 275: 10285-10290. [Abstract] [Full Text] [PDF]

Dorina Avram, Andrew Fields, Karen Pretty On Top, Daniel J. Nevrivy, Jane E. Ishmael, and Mark Leid: Isolation of a Novel Family of C₂H₂ Zinc Finger Proteins Implicated in Transcriptional Repression Mediated by Chicken Ovalbumin Upstream Promoter Transcription Factor (COUP-TF) Orphan Nuclear Receptors
J. Biol. Chem. 2000 275: 10315-10322. [Abstract] [Full Text] [PDF]

Jack C. Reidling, Michael A. Miller, and Robert E. Steele: Sweet Tooth, a Novel Receptor Protein-tyrosine Kinase with C-type Lectin-like Extracellular Domains
J. Biol. Chem. 2000 275: 10323-10330. [Abstract] [Full Text] [PDF]

Bin-Bing S. Zhou, Priya Chaturvedi, Kevin Spring, Shaun P. Scott, Roy A. Johanson, Rubin Mishra, Michael R. Mattern, James D. Winkler, and Kum Kum Khanna: Caffeine Abolishes the Mammalian G₂/M DNA Damage Checkpoint by Inhibiting Ataxia-Telangiectasia-mutated Kinase Activity
J. Biol. Chem. 2000 275: 10342-10348. [Abstract] [Full Text] [PDF]

Matthew B. Beard, Aileen E. Olsen, Randy E. Jones, Suat Erdogan, Miles D. Houslay, and Graeme B. Bolger: UCR1 and UCR2 Domains Unique to the cAMP-specific Phosphodiesterase Family Form a Discrete Module via Electrostatic Interactions
J. Biol. Chem. 2000 275: 10349-10358. [Abstract] [Full Text] [PDF]

Mark T. Bedford, Dilara Sarbassova, Jian Xu, Philip Leder, and Michael B. Yaffe: A Novel Pro-Arg Motif Recognized by WW Domains
J. Biol. Chem. 2000 275: 10359-10369. [Abstract] [Full Text] [PDF]

Christopher V. Carman, Larry S. Barak, Chongguang Chen, Lee-Yuan Liu-Chen, James J. Onorato, Scott P. Kennedy, Marc G. Caron, and Jeffrey L. Benovic: Mutational Analysis of G $beta$ $gamma$ and Phospholipid Interaction with G Protein-coupled Receptor Kinase 2
J. Biol. Chem. 2000 275: 10443-10452. [Abstract] [Full Text] [PDF]

Anne-Odile Hueber, Martin Zörnig, Anne-Marie Bernard, Magali Chautan, and Gerard Evan: A Dominant Negative Fas-associated Death Domain Protein Mutant Inhibits Proliferation and Leads to Impaired Calcium Mobilization in Both T-cells and Fibroblasts
J. Biol. Chem. 2000 275: 10453-10462. [Abstract] [Full Text] [PDF]

Svetlana Tarabykina, Anne Læssøe Møller, Isabelle Durussel, Jos Cox, and Martin W. Berchtold: Two Forms of the Apoptosis-linked Protein ALG-2 with Different Ca²⁺ Affinities and Target Recognition
J. Biol. Chem. 2000 275: 10514-10518. [Abstract] [Full Text] [PDF]

Joseph Lewis, Anne Devin, Abigail Miller, Yong Lin, Yolanda Rodriguez, Len Neckers, and Zheng-gang Liu: Disruption of Hsp90 Function Results in Degradation of the Death Domain Kinase, Receptor-interacting Protein (RIP), and Blockage of Tumor Necrosis Factor-induced Nuclear Factor- $kappa$ B Activation
J. Biol. Chem. 2000 275: 10519-10526. [Abstract] [Full Text] [PDF]

Yun Soo Bae, Jee-Young Sung, Ohn-Soon Kim, Yeun Ju Kim, Kyu Chung Hur, Andrius Kazlauskas, and Sue Goo Rhee: Platelet-derived Growth Factor-induced H₂O₂ Production Requires the Activation of Phosphatidylinositol 3-Kinase
J. Biol. Chem. 2000 275: 10527-10531. [Abstract] [Full Text] [PDF]

Jonathon N. Winnay, Jens C. Brüning, Deborah J. Burks, and C. Ronald Kahn: Gab-1-mediated IGF-1 Signaling in IRS-1-deficient 3T3 Fibroblasts
J. Biol. Chem. 2000 275: 10545-10550. [Abstract] [Full Text] [PDF]

Masanobu Funamoto, Yasushi Fujio, Keita Kunisada, Shinji Negoro, Eiroh Tone, Tomoaki Osugi, Hisao Hirota, Masahiro Izumi, Kazuyuki Yoshizaki, Kenneth Walsh, Tadamitsu Kishimoto, and Keiko Yamauchi-Takihara: Signal Transducer and Activator of Transcription 3 Is Required for Glycoprotein 130-mediated Induction of Vascular Endothelial Growth Factor in Cardiac Myocytes
J. Biol. Chem. 2000 275: 10561-10566. [Abstract] [Full Text] [PDF]

Daniela Gambaletta, Alessandra Marchetti, Laura Benedetti, Arthur M. Mercurio, Ada Sacchi, and Rita Falcioni: Cooperative Signaling between $alpha$ ₆ $beta$ ₄ Integrin and ErbB-2 Receptor Is Required to Promote Phosphatidylinositol 3-Kinase-dependent Invasion
J. Biol. Chem. 2000 275: 10604-10610. [Abstract] [Full Text] [PDF]

Simon Rousseau, François Houle, Helen Kotanides, Larry Witte, Johannes Waltenberger, Jacques Landry, and Jacques Huot: Vascular Endothelial Growth Factor (VEGF)-driven Actin-based Motility Is Mediated by VEGFR2 and Requires Concerted Activation of Stress-activated Protein Kinase 2 (SAPK2/p38) and Geldanamycin-sensitive Phosphorylation of Focal Adhesion Kinase
J. Biol. Chem. 2000 275: 10661-10672. [Abstract] [Full Text] [PDF]

Erica M. Dutil and Alexandra C. Newton: Dual Role of Pseudosubstrate in the Coordinated Regulation of Protein Kinase C by Phosphorylation and Diacylglycerol
J. Biol. Chem. 2000 275: 10697-10701. [Abstract] [Full Text] [PDF]

Molecular Basis Of Cell and Developmental Biology:

Bradford Talcott and Mary Shannon Moore: The Nuclear Import of RCC1 Requires a Specific Nuclear Localization Sequence Receptor, Karyopherin $alpha$ 3/Qip
J. Biol. Chem. 2000 275: 10099-10104. [Abstract] [Full Text] [PDF]

Shigeru Kanda, Edwina C. Lerner, Satoshi Tsuda, Takefumi Shono, Hiroshi Kanetake, and Thomas E. Smithgall: The Nonreceptor Protein-tyrosine Kinase c-Fes Is Involved in Fibroblast Growth Factor-2-induced Chemotaxis of Murine Brain Capillary Endothelial Cells
J. Biol. Chem. 2000 275: 10105-10111. [Abstract] [Full Text] [PDF]

Theresa Li-Yun Chang, Xianbu Peng, and Xin-Yuan Fu: Interleukin-4 Mediates Cell Growth Inhibition through Activation of Stat1
J. Biol. Chem. 2000 275: 10212-10217. [Abstract] [Full Text] [PDF]

Irina Agarkova, Daniel Auerbach, Elisabeth Ehler, and Jean-Claude Perriard: A Novel Marker for Vertebrate Embryonic Heart, the EH-myomesin Isoform
J. Biol. Chem. 2000 275: 10256-10264. [Abstract] [Full Text] [PDF]

Keiko Satoh-Horikawa, Hiroyuki Nakanishi, Kenichi Takahashi, Masako Miyahara, Miyuki Nishimura, Kouichi Tachibana, Akira Mizoguchi, and Yoshimi Takai: Nectin-3, a New Member of Immunoglobulin-like Cell Adhesion Molecules That Shows Homophilic and Heterophilic Cell-Cell Adhesion Activities
J. Biol. Chem. 2000 275: 10291-10299. [Abstract] [Full Text] [PDF]

Shinji Tanaka, Takashi Uehara, and Yasuyuki Nomura: Up-regulation of Protein-disulfide Isomerase in Response to Hypoxia/Brain Ischemia and Its Protective Effect against Apoptotic Cell Death
J. Biol. Chem. 2000 275: 10388-10393. [Abstract] [Full Text] [PDF]

Stefanie Gehring, Sabine Rottmann, Annette R. Menkel, Jürgen Mertsching, Anja Krippner-Heidenreich, and Bernhard Lüscher: Inhibition of Proliferation and Apoptosis by the Transcriptional Repressor Mad1. REPRESSION OF Fas-INDUCED CASPASE-8 ACTIVATION
J. Biol. Chem. 2000 275: 10413-10420. [Abstract] [Full Text] [PDF]

Yoshitaka Nagai, Timothy Tucker, Hongzu Ren, Daniel J. Kenan, Barry S. Henderson, Jack D. Keene, Warren J. Strittmatter, and James R. Burke: Inhibition of Polyglutamine Protein Aggregation and Cell Death by Novel Peptides Identified by Phage Display Screening
J. Biol. Chem. 2000 275: 10437-10442. [Abstract] [Full Text] [PDF]

Keisuke Nakajima, Atsushi Takahashi, and Yoshio Yaoita: Structure, Expression, and Function of the Xenopus laevis Caspase Family
J. Biol. Chem. 2000 275: 10484-10491. [Abstract] [Full Text] [PDF]

Additions and Corrections:

IngMarie Nilsson, Susanne Witt, Hans Kiefer, Ismael Mingarro, and Gunnar von Heijne: Distant downstream sequence determinants can control N-tail translocation during protein insertion into the endoplasmic reticulum membrane.
J. Biol. Chem. 2000 275: 10716. [Full Text] [PDF]