Editorial:

HighWire Press Is 5 years old
J. Biol. Chem. 2000 275: 12361. [Full Text] [PDF]  

Accelerated Publications:

William T. Pu, Kevin Wickman, and David E. Clapham

ICln Is Essential for Cellular and Early Embryonic Viability
J. Biol. Chem. 2000 275: 12363-12366. [Abstract] [Full Text] [PDF]  

DNA: Replication Repair and Recombination:

Kevin G. Pinz and Daniel F. Bogenhagen

Characterization of a Catalytically Slow AP Lyase Activity in DNA Polymerase  and Other Family A DNA Polymerases
J. Biol. Chem. 2000 275: 12509-12514. [Abstract] [Full Text] [PDF]  

Barbara Corneo, Despina Moshous, Isabelle Callebaut, Régina de Chasseval, Alain Fischer, and Jean-Pierre de Villartay

Three-dimensional Clustering of Human RAG2 Gene Mutations in Severe Combined Immune Deficiency
J. Biol. Chem. 2000 275: 12672-12675. [Abstract] [Full Text] [PDF]  

Alexandra Vaisman and Stephen G. Chaney

The Efficiency and Fidelity of Translesion Synthesis past Cisplatin and Oxaliplatin GpG Adducts by Human DNA Polymerase
J. Biol. Chem. 2000 275: 13017-13025. [Abstract] [Full Text] [PDF]  

Genes: Structure and Regulation:

Laurie A. Stargell, Zarmik Moqtaderi, David R. Dorris, Ryan C. Ogg, and Kevin Struhl

TFIIA Has Activator-dependent and Core Promoter Functions in Vivo
J. Biol. Chem. 2000 275: 12374-12380. [Abstract] [Full Text] [PDF]  

David Solecki, Günter Bernhardt, Martin Lipp, and Eckard Wimmer

Identification of a Nuclear Respiratory Factor-1 Binding Site within the Core Promoter of the human polio virus receptor/CD155 Gene
J. Biol. Chem. 2000 275: 12453-12462. [Abstract] [Full Text] [PDF]  

Soo-Kyung Lee, Jung-Hyun Kim, Young Chul Lee, JaeHun Cheong, and Jae Woon Lee

Silencing Mediator of Retinoic Acid and Thyroid Hormone Receptors, as a Novel Transcriptional Corepressor Molecule of Activating Protein-1, Nuclear Factor-B, and Serum Response Factor
J. Biol. Chem. 2000 275: 12470-12474. [Abstract] [Full Text] [PDF]  

Jian-Ming Gu, Kenji Fukudome, and Charles T. Esmon

Characterization and Regulation of the 5'-Flanking Region of the Murine Endothelial Protein C Receptor Gene
J. Biol. Chem. 2000 275: 12481-12488. [Abstract] [Full Text] [PDF]  

Ryuichiro Sato, Akihiro Okamoto, Jun Inoue, Wataru Miyamoto, Yuko Sakai, Noriaki Emoto, Hitoshi Shimano, and Masatomo Maeda

Transcriptional Regulation of the ATP Citrate-lyase Gene by Sterol Regulatory Element-binding Proteins
J. Biol. Chem. 2000 275: 12497-12502. [Abstract] [Full Text] [PDF]  

Evi Soutoglou, George Papafotiou, Nitsa Katrakili, and Iannis Talianidis

Transcriptional Activation by Hepatocyte Nuclear Factor-1 Requires Synergism between Multiple Coactivator Proteins
J. Biol. Chem. 2000 275: 12515-12520. [Abstract] [Full Text] [PDF]  

Sukhinder K. Cheema and Luis B. Agellon

The Murine and Human Cholesterol 7-Hydroxylase Gene Promoters Are Differentially Responsive to Regulation by Fatty Acids Mediated via Peroxisome Proliferator-activated Receptor
J. Biol. Chem. 2000 275: 12530-12536. [Abstract] [Full Text] [PDF]  

Geneviève Martin, Hélène Poirier, Nathalie Hennuyer, Diane Crombie, Jean Charles Fruchart, Richard A. Heyman, Philippe Besnard, and Johan Auwerx

Induction of the Fatty Acid Transport Protein 1 and Acyl-CoA Synthase Genes by Dimer-selective Rexinoids Suggests That the Peroxisome Proliferator-activated Receptor-Retinoid X Receptor Heterodimer Is Their Molecular Target
J. Biol. Chem. 2000 275: 12612-12618. [Abstract] [Full Text] [PDF]  

Sanjit K. Roy, S. James Wachira, Xiao Weihua, Junbo Hu, and Dhananjaya V. Kalvakolanu

CCAAT/Enhancer-binding Protein- Regulates Interferon-induced Transcription through a Novel Element
J. Biol. Chem. 2000 275: 12626-12632. [Abstract] [Full Text] [PDF]  

Ying Liu, Haochuan Li, Kazuhiro Tanaka, Noriyuki Tsumaki, and Yoshihiko Yamada

Identification of an Enhancer Sequence within the First Intron Required for Cartilage-specific Transcription of the 2(XI) Collagen Gene
J. Biol. Chem. 2000 275: 12712-12718. [Abstract] [Full Text] [PDF]  

Dmitry Kulish, Jookyung Lee, Ivan Lomakin, Beata Nowicka, Asis Das, Seth Darst, Kristjan Normet, and Sergei Borukhov

The Functional Role of Basic Patch, a Structural Element of Escherichia coli Transcript Cleavage Factors GreA and GreB
J. Biol. Chem. 2000 275: 12789-12798. [Abstract] [Full Text] [PDF]  

Guido Boehmelt, Irene Fialka, Greg Brothers, Michael D. McGinley, Scott D. Patterson, Rong Mo, Chi Chung Hui, Stephen Chung, Lukas A. Huber, Tak W. Mak, and Norman N. Iscove

Cloning and Characterization of the Murine Glucosamine-6-phosphate Acetyltransferase EMeg32. DIFFERENTIAL EXPRESSION AND INTRACELLULAR MEMBRANE ASSOCIATION
J. Biol. Chem. 2000 275: 12821-12832. [Abstract] [Full Text] [PDF]  

Elzbieta Wieczorek, Zhili Lin, E. Brent Perkins, David J. Law, Juanita L. Merchant, and Zendra E. Zehner

The Zinc Finger Repressor, ZBP-89, Binds to the Silencer Element of the Human Vimentin Gene and Complexes with the Transcriptional Activator, Sp1
J. Biol. Chem. 2000 275: 12879-12888. [Abstract] [Full Text] [PDF]  

Jane Fellows, Hediye Erdjument-Bromage, Paul Tempst, and Jesper Q. Svejstrup

The Elp2 Subunit of Elongator and Elongating RNA Polymerase II Holoenzyme Is a WD40 Repeat Protein
J. Biol. Chem. 2000 275: 12896-12899. [Abstract] [Full Text] [PDF]  

Cristina Pérez-Sánchez, María Ana Gómez-Ferrería, Carmen Arias de la Fuente, Begoña Granadino, Gloria Velasco, Andrés Esteban-Gamboa, and Javier Rey-Campos

FHX, a Novel Fork Head Factor with a Dual DNA Binding Specificity
J. Biol. Chem. 2000 275: 12909-12916. [Abstract] [Full Text] [PDF]  

Stephen D. Bell and Stephen P. Jackson

The Role of Transcription Factor B in Transcription Initiation and Promoter Clearance in the Archaeon Sulfolobus acidocaldarius
J. Biol. Chem. 2000 275: 12934-12940. [Abstract] [Full Text] [PDF]  

Sabine Short, Di Tian, Marc L. Short, and Richard A. Jungmann

Structural Determinants for Post-transcriptional Stabilization of Lactate Dehydrogenase A mRNA by the Protein Kinase C Signal Pathway
J. Biol. Chem. 2000 275: 12963-12969. [Abstract] [Full Text] [PDF]  

Julio E. Herrera, R. Louis Schiltz, and Michael Bustin

The Accessibility of Histone H3 Tails in Chromatin Modulates Their Acetylation by P300/CBP-associated Factor
J. Biol. Chem. 2000 275: 12994-12999. [Abstract] [Full Text] [PDF]  

Michael J. Kelner, Richard D. Bagnell, Mark A. Montoya, Leita A. Estes, Lena Forsberg, and Ralf Morgenstern

Structural Organization of the Microsomal Glutathione S-Transferase Gene (MGST1) on Chromosome 12p13.1-13.2. IDENTIFICATION OF THE CORRECT PROMOTER REGION AND DEMONSTRATION OF TRANSCRIPTIONAL REGULATION IN RESPONSE TO OXIDATIVE STRESS
J. Biol. Chem. 2000 275: 13000-13006. [Abstract] [Full Text] [PDF]  

Ruth A. Keri, Daniel J. Bachmann, Alireza Behrooz, Brian D. Herr, Rebecca K. Ameduri, Christine C. Quirk, and John H. Nilson

An NF-Y Binding Site Is Important for Basal, but Not Gonadotropin-releasing Hormone-stimulated, Expression of the Luteinizing Hormone  Subunit Gene
J. Biol. Chem. 2000 275: 13082-13088. [Abstract] [Full Text] [PDF]  

RNA: Structure Metabolism and Catalysis:

Winfried Hausner, Udo Lange, and Meike Musfeldt

Transcription Factor S, a Cleavage Induction Factor of the Archaeal RNA Polymerase
J. Biol. Chem. 2000 275: 12393-12399. [Abstract] [Full Text] [PDF]  

Julie M. Tebo, Shyamasree Datta, Raj Kishore, Mikhail Kolosov, Jennifer A. Major, Yoshihiro Ohmori, and Thomas A. Hamilton

Interleukin-1-mediated Stabilization of Mouse KC mRNA Depends on Sequences in both 5'- and 3'-Untranslated Regions
J. Biol. Chem. 2000 275: 12987-12993. [Abstract] [Full Text] [PDF]  

Protein Synthesis Post-Translation Modification and Degradation:

Florian A. Salomons, Jan A. K. W. Kiel, Klaas Nico Faber, Marten Veenhuis, and Ida J. van der Klei

Overproduction of Pex5p Stimulates Import of Alcohol Oxidase and Dihydroxyacetone Synthase in a Hansenula polymorpha pex14 Null Mutant
J. Biol. Chem. 2000 275: 12603-12611. [Abstract] [Full Text] [PDF]  

Bruno Méhul, Dominique Bernard, Lucie Simonetti, Marie Alix Bernard, and Rainer Schmidt

Identification and Cloning of a New Calmodulin-like Protein from Human Epidermis
J. Biol. Chem. 2000 275: 12841-12847. [Abstract] [Full Text] [PDF]  

Jakob H. Waterborg

Steady-state Levels of Histone Acetylation in Saccharomyces cerevisiae
J. Biol. Chem. 2000 275: 13007-13011. [Abstract] [Full Text] [PDF]  

Ursula G. Danilczyk, Myrna F. Cohen-Doyle, and David B. Williams

Functional Relationship between Calreticulin, Calnexin, and the Endoplasmic Reticulum Luminal Domain of Calnexin
J. Biol. Chem. 2000 275: 13089-13097. [Abstract] [Full Text] [PDF]  

Hui-Jye Chen, Ching-Long Hwong, Cheng-Hsu Wang, and Jaulang Hwang

Degradation of DNA Topoisomerase I by a Novel Trypsin-like Serine Protease in Proliferating Human T Lymphocytes
J. Biol. Chem. 2000 275: 13109-13117. [Abstract] [Full Text] [PDF]  

Genomics Proteomics and Bioinformatics:

Jianxin Mai, Russell L. Finley, Jr., David M. Waisman, and Bonnie F. Sloane

Human Procathepsin B Interacts with the Annexin II Tetramer on the Surface of Tumor Cells
J. Biol. Chem. 2000 275: 12806-12812. [Abstract] [Full Text] [PDF]  

Protein Structure and Folding:

Yo-hei Watanabe, Ken Motohashi, Hideki Taguchi, and Masasuke Yoshida

Heat-inactivated Proteins Managed by DnaKJ-GrpE-ClpB Chaperones Are Released as a Chaperonin-recognizable Non-native Form
J. Biol. Chem. 2000 275: 12388-12392. [Abstract] [Full Text] [PDF]  

Kazuhiko Adachi, Yi Zhao, Takamasa Yamaguchi, and Saul Surrey

Assembly of - with -Globin Chains to Form Human Fetal Hemoglobin in Vitro and in Vivo
J. Biol. Chem. 2000 275: 12424-12429. [Abstract] [Full Text] [PDF]  

Kenji Inaba, Koichiro Ishimori, Kiyohiro Imai, and Isao Morishima

Substitution of the Heme Binding Module in Hemoglobin - and -Subunits. IMPLICATION FOR DIFFERENT REGULATION MECHANISMS OF THE HEME PROXIMAL STRUCTURE BETWEEN HEMOGLOBIN AND MYOGLOBIN
J. Biol. Chem. 2000 275: 12438-12445. [Abstract] [Full Text] [PDF]  

B. K. Muralidhara and Masaaki Hirose

Anion-mediated Iron Release from Transferrins. THE KINETIC AND MECHANISTIC MODEL FOR N-LOBE OF OVOTRANSFERRIN
J. Biol. Chem. 2000 275: 12463-12469. [Abstract] [Full Text] [PDF]  

Deirdre A. Sullivan and Jonathan B. Cohen

Mapping the Agonist Binding Site of the Nicotinic Acetylcholine Receptor. ORIENTATION REQUIREMENTS FOR ACTIVATION BY COVALENT AGONIST
J. Biol. Chem. 2000 275: 12651-12660. [Abstract] [Full Text] [PDF]  

Nina Bren and Steven M. Sine

Hydrophobic Pairwise Interactions Stabilize -Conotoxin MI in the Muscle Acetylcholine Receptor Binding Site
J. Biol. Chem. 2000 275: 12692-12700. [Abstract] [Full Text] [PDF]  

Raghu Kalluri and Dominic Cosgrove

Assembly of Type IV Collagen. INSIGHTS FROM 3(IV) COLLAGEN-DEFICIENT MICE
J. Biol. Chem. 2000 275: 12719-12724. [Abstract] [Full Text] [PDF]  

Sona Vasudevan, James R. Roberts, Richard A. McClintock, Judith A. Dent, Reha Celikel, Jerry Ware, Kottayil I. Varughese, and Zaverio M. Ruggeri

Modeling and Functional Analysis of the Interaction between von Willebrand Factor A1 Domain and Glycoprotein Ib
J. Biol. Chem. 2000 275: 12763-12768. [Abstract] [Full Text] [PDF]  

Caroline Jegerschöld, A. William Rutherford, Tony A. Mattioli, Massimo Crimi, and Roberto Bassi

Calcium Binding to the Photosystem II Subunit CP29
J. Biol. Chem. 2000 275: 12781-12788. [Abstract] [Full Text] [PDF]  

Yoshiyuki Nishimiya, Kouhei Tsumoto, Mitsunori Shiroishi, Katsuhide Yutani, and Izumi Kumagai

Thermodynamic Consequences of Grafting Enhanced Affinity toward the Mutated Antigen onto an Antibody. THE CASE OF ANTI-LYSOZYME ANTIBODY, HyHEL-10
J. Biol. Chem. 2000 275: 12813-12820. [Abstract] [Full Text] [PDF]  

Enzyme Catalysis and Regulation:

Aimin Liu and Astrid Gräslund

Electron Paramagnetic Resonance Evidence for a Novel Interconversion of [3Fe-4S]⁺ and [4Fe-4S]⁺ Clusters with Endogenous Iron and Sulfide in Anaerobic Ribonucleotide Reductase Activase in Vitro
J. Biol. Chem. 2000 275: 12367-12373. [Abstract] [Full Text] [PDF] Supplemental Figures  

Deborah A. Hogan, Sheila R. Smith, Eric A. Saari, John McCracken, and Robert P. Hausinger

Site-directed Mutagenesis of 2,4-Dichlorophenoxyacetic Acid/-Ketoglutarate Dioxygenase. IDENTIFICATION OF RESIDUES INVOLVED IN METALLOCENTER FORMATION AND SUBSTRATE BINDING
J. Biol. Chem. 2000 275: 12400-12409. [Abstract] [Full Text] [PDF]  

Pauline F. Marx, Tilman M. Hackeng, Philip E. Dawson, John H. Griffin, Joost C. M. Meijers, and Bonno N. Bouma

Inactivation of Active Thrombin-activable Fibrinolysis Inhibitor Takes Place by a Process That Involves Conformational Instability Rather Than Proteolytic Cleavage
J. Biol. Chem. 2000 275: 12410-12415. [Abstract] [Full Text] [PDF]  

Nathalie Y. R. Imbeault, Justin B. Powlowski, Christopher L. Colbert, Jeffrey T. Bolin, and Lindsay D. Eltis

Steady-state Kinetic Characterization and Crystallization of a Polychlorinated Biphenyl-transforming Dioxygenase
J. Biol. Chem. 2000 275: 12430-12437. [Abstract] [Full Text] [PDF]  

Mei-Huei Jang, Nigel S. Scrutton, and Russ Hille

Formation of W₃A₁ Electron-transferring Flavoprotein (ETF) Hydroquinone in the Trimethylamine Dehydrogenase·ETF Protein Complex
J. Biol. Chem. 2000 275: 12546-12552. [Abstract] [Full Text] [PDF]  

Anne M. Gardner, Lori A. Martin, Paul R. Gardner, Yi Dou, and John S. Olson

Steady-state and Transient Kinetics of Escherichia coli Nitric-oxide Dioxygenase (Flavohemoglobin). THE B10 TYROSINE HYDROXYL IS ESSENTIAL FOR DIOXYGEN BINDING AND CATALYSIS
J. Biol. Chem. 2000 275: 12581-12589. [Abstract] [Full Text] [PDF]  

Robert G. Keefe, Gladys F. Maley, Ruth L. Saxl, and Frank Maley

A T4-phage Deoxycytidylate Deaminase Mutant That No Longer Requires Deoxycytidine 5'-Triphosphate for Activation
J. Biol. Chem. 2000 275: 12598-12602. [Abstract] [Full Text] [PDF]  

Yuji Ikari, Kazuo Fujikawa, Karen O. Yee, and Stephen M. Schwartz

₁-Proteinase Inhibitor, ₁-Antichymotrypsin, or ₂-Macroglobulin Is Required for Vascular Smooth Muscle Cell Spreading in Three-dimensional Fibrin Gel
J. Biol. Chem. 2000 275: 12799-12805. [Abstract] [Full Text] [PDF]  

Michael B. Boffa, Robert Bell, Willem K. Stevens, and Michael E. Nesheim

Roles of Thermal Instability and Proteolytic Cleavage in Regulation of Activated Thrombin-activable Fibrinolysis Inhibitor
J. Biol. Chem. 2000 275: 12868-12878. [Abstract] [Full Text] [PDF]  

Michael J. Corey, Robert J. Kinders, Cristina M. Poduje, Connie L. Bruce, Halli Rowley, Lisha G. Brown, G. Michael Hass, and Robert L. Vessella

Mechanistic Studies of the Effects of Anti-factor H Antibodies on Complement-mediated Lysis
J. Biol. Chem. 2000 275: 12917-12925. [Abstract] [Full Text] [PDF]  

Hideki Yokoyama, Naomi Mukae, Hideki Sakahira, Katsuya Okawa, Akihiro Iwamatsu, and Shigekazu Nagata

A Novel Activation Mechanism of Caspase-activated DNase from Drosophila melanogaster
J. Biol. Chem. 2000 275: 12978-12986. [Abstract] [Full Text] [PDF]  

Lotte Bjergbaek, Paul Kingma, Inga Sig Nielsen, Yong Wang, Ole Westergaard, Neil Osheroff, and Anni H. Andersen

Communication between the ATPase and Cleavage/Religation Domains of Human Topoisomerase II
J. Biol. Chem. 2000 275: 13041-13048. [Abstract] [Full Text] [PDF]  

Colleen D. Kelleher and James J. Champoux

RNA Degradation and Primer Selection by Moloney Murine Leukemia Virus Reverse Transcriptase Contribute to the Accuracy of Plus Strand Initiation
J. Biol. Chem. 2000 275: 13061-13070. [Abstract] [Full Text] [PDF]  

Syed S. Ahmad, Joseph M. Scandura, and Peter N. Walsh

Structural and Functional Characterization of Platelet Receptor-mediated Factor VIII Binding
J. Biol. Chem. 2000 275: 13071-13081. [Abstract] [Full Text] [PDF]  

Pei-Feng Chen and Kenneth K. Wu

Characterization of the Roles of the 594-645 Region in Human Endothelial Nitric-oxide Synthase in Regulating Calmodulin Binding and Electron Transfer
J. Biol. Chem. 2000 275: 13155-13163. [Abstract] [Full Text] [PDF]  

Metabolism and Bioenergetics:

Tanya Jonassen and Catherine F. Clarke

Isolation and Functional Expression of Human COQ3, a Gene Encoding a Methyltransferase Required for Ubiquinone Biosynthesis
J. Biol. Chem. 2000 275: 12381-12387. [Abstract] [Full Text] [PDF]  

Jacob M. Jones, James C. Morrell, and Stephen J. Gould

Identification and Characterization of HAOX1, HAOX2, and HAOX3, Three Human Peroxisomal 2-Hydroxy Acid Oxidases
J. Biol. Chem. 2000 275: 12590-12597. [Abstract] [Full Text] [PDF]  

Dirk Bald, Hiroyuki Noji, Michael T. Stumpp, Masasuke Yoshida, and Toru Hisabori

ATPase Activity of a Highly Stable ₃₃ Subcomplex of Thermophilic F₁ Can Be Regulated by the Introduced Regulatory Region of  Subunit of Chloroplast F₁
J. Biol. Chem. 2000 275: 12757-12762. [Abstract] [Full Text] [PDF]  

Christian Vélot and Paul A. Srere

Reversible Transdominant Inhibition of a Metabolic Pathway. IN VIVO EVIDENCE OF INTERACTION BETWEEN TWO SEQUENTIAL TRICARBOXYLIC ACID CYCLE ENZYMES IN YEAST
J. Biol. Chem. 2000 275: 12926-12933. [Abstract] [Full Text] [PDF]  

John J. McGuire, Cynthia A. Russell, and Malgorzata Balinska

Human Cytosolic and Mitochondrial Folylpolyglutamate Synthetase Are Electrophoretically Distinct. EXPRESSION IN ANTIFOLATE-SENSITIVE AND -RESISTANT HUMAN CELL LINES
J. Biol. Chem. 2000 275: 13012-13016. [Abstract] [Full Text] [PDF]  

Ronald P. Herzig, Salvatore Scacco, and Richard C. Scarpulla

Sequential Serum-dependent Activation of CREB and NRF-1 Leads to Enhanced Mitochondrial Respiration through the Induction of Cytochrome c
J. Biol. Chem. 2000 275: 13134-13141. [Abstract] [Full Text] [PDF]  

Glycobiology and Extracellular Matrices:

Leonie Beljaars, Grietje Molema, Detlef Schuppan, Albert Geerts, Pieter J. De Bleser, Betty Weert, Dirk K. F. Meijer, and Klaas Poelstra

Successful Targeting to Rat Hepatic Stellate Cells Using Albumin Modified with Cyclic Peptides That Recognize the Collagen Type VI Receptor
J. Biol. Chem. 2000 275: 12743-12751. [Abstract] [Full Text] [PDF]  

Rinat Eshel, Alexandra Zanin, Orit Sagi-Assif, Tzipi Meshel, Nechama I. Smorodinsky, Oren Dwir, Ronen Alon, Ruud Brakenhoff, Guus van Dongen, and Isaac P. Witz

The GPI-linked Ly-6 Antigen E48 Regulates Expression Levels of the FX Enzyme and of E-selectin Ligands on Head and Neck Squamous Carcinoma Cells
J. Biol. Chem. 2000 275: 12833-12840. [Abstract] [Full Text] [PDF]  

Lipids and Lipoproteins:

Kenneth G. Milne and Michael A. J. Ferguson

Cloning, Expression, and Characterization of the acyl-CoA-binding Protein in African Trypanosomes
J. Biol. Chem. 2000 275: 12503-12508. [Abstract] [Full Text] [PDF]  

Andrey Frolov, Anca Petrescu, Barbara P. Atshaves, Peter T. C. So, Enrico Gratton, Ginette Serrero, and Friedhelm Schroeder

High Density Lipoprotein-mediated Cholesterol Uptake and Targeting to Lipid Droplets in Intact L-cell Fibroblasts. A SINGLE- AND MULTIPHOTON FLUORESCENCE APPROACH
J. Biol. Chem. 2000 275: 12769-12780. [Abstract] [Full Text] [PDF]  

Membrane Transport Structure Function and Biogenesis:

Amanda L. Horstman and Meta J. Kuehn

Enterotoxigenic Escherichia coli Secretes Active Heat-labile Enterotoxin via Outer Membrane Vesicles
J. Biol. Chem. 2000 275: 12489-12496. [Abstract] [Full Text] [PDF]  

Maria-Isabel Fortea, Fernando Soler, and Francisco Fernandez-Belda

Insight into the Uncoupling Mechanism of Sarcoplasmic Reticulum ATPase Using the Phosphorylating Substrate UTP
J. Biol. Chem. 2000 275: 12521-12529. [Abstract] [Full Text] [PDF]  

Vazhaikkurichi M. Rajendran, Pitchai Sangan, John Geibel, and Henry J. Binder

Ouabain-sensitive H,K-ATPase Functions as Na,K-ATPase in Apical Membranes of Rat Distal Colon
J. Biol. Chem. 2000 275: 13035-13040. [Abstract] [Full Text] [PDF]  

Mian Gao, Heng-Ran Cui, Douglas W. Loe, Caroline E. Grant, Kurt C. Almquist, Susan P. C. Cole, and Roger G. Deeley

Comparison of the Functional Characteristics of the Nucleotide Binding Domains of Multidrug Resistance Protein 1
J. Biol. Chem. 2000 275: 13098-13108. [Abstract] [Full Text] [PDF]  

Mechanisms Of Signal Transduction:

Inbal Hazan-Halevy, Rony Seger, and Rachel Levy

The Requirement of Both Extracellular Regulated Kinase and p38 Mitogen-activated Protein Kinase for Stimulation of Cytosolic Phospholipase A₂ Activity by Either FcRIIA or FcRIIIB in Human Neutrophils. A POSSIBLE ROLE FOR Pyk2 BUT NOT FOR THE Grb2-Sos-Shc COMPLEX
J. Biol. Chem. 2000 275: 12416-12423. [Abstract] [Full Text] [PDF]  

Christophe Blanchetot and Jeroen den Hertog

Multiple Interactions between Receptor Protein-tyrosine Phosphatase (RPTP)  and Membrane-distal Protein-tyrosine Phosphatase Domains of Various RPTPs
J. Biol. Chem. 2000 275: 12446-12452. [Abstract] [Full Text] [PDF]  

Dennis A. Ricupero, Jose R. Romero, David C. Rishikof, and Ronald H. Goldstein

Des-Arg¹⁰-kallidin Engagement of the B1 Receptor Stimulates Type I Collagen Synthesis via Stabilization of Connective Tissue Growth Factor mRNA
J. Biol. Chem. 2000 275: 12475-12480. [Abstract] [Full Text] [PDF]  

Moritz Bünemann, Thomas Meyer, Lutz Pott, and Marlene Hosey

Novel Inhibition of G-activated Potassium Currents Induced by M₂ Muscarinic Receptors via a Pertussis Toxin-insensitive Pathway
J. Biol. Chem. 2000 275: 12537-12545. [Abstract] [Full Text] [PDF]  

Seung Hyun Yoo, Seung Ho So, Hee Seok Kweon, Jin Soo Lee, Moon Kyung Kang, and Choon Ju Jeon

Coupling of the Inositol 1,4,5-Trisphosphate Receptor and Chromogranins A and B in Secretory Granules
J. Biol. Chem. 2000 275: 12553-12559. [Abstract] [Full Text] [PDF]  

Serge Y. Fuchs, Inger Tappin, and Ze'ev Ronai

Stability of the ATF2 Transcription Factor Is Regulated by Phosphorylation and Dephosphorylation
J. Biol. Chem. 2000 275: 12560-12564. [Abstract] [Full Text] [PDF]  

Claire A. Molloy, Felicity E. B. May, and Bruce R. Westley

Insulin Receptor Substrate-1 Expression Is Regulated by Estrogen in the MCF-7 Human Breast Cancer Cell Line
J. Biol. Chem. 2000 275: 12565-12571. [Abstract] [Full Text] [PDF]  

Stephen J. Keely, Sean O. Calandrella, and Kim E. Barrett

Carbachol-stimulated Transactivation of Epidermal Growth Factor Receptor and Mitogen-activated Protein Kinase in T₈₄ Cells Is Mediated by Intracellular Ca²⁺, PYK-2, and p60^src
J. Biol. Chem. 2000 275: 12619-12625. [Abstract] [Full Text] [PDF]  

Luciano Cominacini, Anna Fratta Pasini, Ulisse Garbin, Anna Davoli, Maria L. Tosetti, Mario Campagnola, Anna Rigoni, Antonio M. Pastorino, Vincenzo Lo Cascio, and Tatsuya Sawamura

Oxidized Low Density Lipoprotein (ox-LDL) Binding to ox-LDL Receptor-1 in Endothelial Cells Induces the Activation of NF-B through an Increased Production of Intracellular Reactive Oxygen Species
J. Biol. Chem. 2000 275: 12633-12638. [Abstract] [Full Text] [PDF]  

Ivo M. B. Francischetti, José M. C. Ribeiro, Donald Champagne, and John Andersen

Purification, Cloning, Expression, and Mechanism of Action of a Novel Platelet Aggregation Inhibitor from the Salivary Gland of the Blood-sucking Bug, Rhodnius prolixus
J. Biol. Chem. 2000 275: 12639-12650. [Abstract] [Full Text] [PDF]  

Leon Su and Michael David

Distinct Mechanisms of STAT Phosphorylation via the Interferon-/ Receptor. SELECTIVE INHIBITION OF STAT3 AND STAT5 BY PICEATANNOL
J. Biol. Chem. 2000 275: 12661-12666. [Abstract] [Full Text] [PDF]  

Naoki Mochizuki, Yusuke Ohba, Shin Kobayashi, Naomi Otsuka, Ann M. Graybiel, Shinya Tanaka, and Michiyuki Matsuda

Crk Activation of JNK via C3G and R-Ras
J. Biol. Chem. 2000 275: 12667-12671. [Abstract] [Full Text] [PDF]  

Victoria Moreno-Manzano, Yoshihisa Ishikawa, Javier Lucio-Cazana, and Masanori Kitamura

Selective Involvement of Superoxide Anion, but Not Downstream Compounds Hydrogen Peroxide and Peroxynitrite, in Tumor Necrosis Factor--induced Apoptosis of Rat Mesangial Cells
J. Biol. Chem. 2000 275: 12684-12691. [Abstract] [Full Text] [PDF]  

Michael Kühl, Laird C. Sheldahl, Craig C. Malbon, and Randall T. Moon

Ca²⁺/Calmodulin-dependent Protein Kinase II Is Stimulated by Wnt and Frizzled Homologs and Promotes Ventral Cell Fates in Xenopus
J. Biol. Chem. 2000 275: 12701-12711. [Abstract] [Full Text] [PDF]  

Robert T. Glover, Maria Angiolieri, Steven Kelly, Daniel T. Monaghan, Jean Y. J. Wang, Thomas E. Smithgall, and Amy L. Buller

Interaction of the N-Methyl-D-Aspartic Acid Receptor NR2D Subunit with the c-Abl Tyrosine Kinase
J. Biol. Chem. 2000 275: 12725-12729. [Abstract] [Full Text] [PDF]  

James J. Caffrey, Stephen T. Safrany, Xiaonian Yang, and Stephen B. Shears

Discovery of Molecular and Catalytic Diversity among Human Diphosphoinositol-Polyphosphate Phosphohydrolases. AN EXPANDING NUDT FAMILY
J. Biol. Chem. 2000 275: 12730-12736. [Abstract] [Full Text] [PDF]  

Jochen Schmitz, Manuela Weissenbach, Serge Haan, Peter C. Heinrich, and Fred Schaper

SOCS3 Exerts Its Inhibitory Function on Interleukin-6 Signal Transduction through the SHP2 Recruitment Site of gp130
J. Biol. Chem. 2000 275: 12848-12856. [Abstract] [Full Text] [PDF]  

Tara L. Sander, Amy L. Haas, Michael J. Peterson, and Jennifer F. Morris

Identification of a Novel SCAN Box-related Protein That Interacts with MZF1B. THE LEUCINE-RICH SCAN BOX MEDIATES HETERO- AND HOMOPROTEIN ASSOCIATIONS
J. Biol. Chem. 2000 275: 12857-12867. [Abstract] [Full Text] [PDF]  

Naoki Nakashima, Prem M. Sharma, Takeshi Imamura, Robert Bookstein, and Jerrold M. Olefsky

The Tumor Suppressor PTEN Negatively Regulates Insulin Signaling in 3T3-L1 Adipocytes
J. Biol. Chem. 2000 275: 12889-12895. [Abstract] [Full Text] [PDF]  

Stuart J. Mundell and Jeffrey L. Benovic

Selective Regulation of Endogenous G Protein-coupled Receptors by Arrestins in HEK293 Cells
J. Biol. Chem. 2000 275: 12900-12908. [Abstract] [Full Text] [PDF]  

Corine Bertolotto, Jean-Ehrland Ricci, Frédéric Luciano, Bernard Mari, Jean-Claude Chambard, and Patrick Auberger

Cleavage of the Serum Response Factor during Death Receptor-induced Apoptosis Results in an Inhibition of the c-FOS Promoter Transcriptional Activity
J. Biol. Chem. 2000 275: 12941-12947. [Abstract] [Full Text] [PDF]  

Sarah M. Short, José L. Boyer, and R. L. Juliano

Integrins Regulate the Linkage between Upstream and Downstream Events in G Protein-coupled Receptor Signaling to Mitogen-activated Protein Kinase
J. Biol. Chem. 2000 275: 12970-12977. [Abstract] [Full Text] [PDF]  

Chandan K. Sen, Savita Khanna, Sashwati Roy, and Lester Packer

Molecular Basis of Vitamin E Action. TOCOTRIENOL POTENTLY INHIBITS GLUTAMATE-INDUCED pp60^c-Src KINASE ACTIVATION AND DEATH OF HT4 NEURONAL CELLS
J. Biol. Chem. 2000 275: 13049-13055. [Abstract] [Full Text] [PDF]  

Susumu Tomita, Takashi Fujita, Yutaka Kirino, and Toshiharu Suzuki

PDZ Domain-dependent Suppression of NF-B/p65-induced A42 Production by a Neuron-specific X11-like Protein
J. Biol. Chem. 2000 275: 13056-13060. [Abstract] [Full Text] [PDF]  

Charito S. Buensuceso and Timothy E. O'Toole

The Association of CRKII with C3G Can be Regulated by Integrins and Defines a Novel Means to Regulate the Mitogen-activated Protein Kinases
J. Biol. Chem. 2000 275: 13118-13125. [Abstract] [Full Text] [PDF]  

James Herrington, Maria Diakonova, Liangyou Rui, David R. Gunter, and Christin Carter-Su

SH2-B Is Required for Growth Hormone-induced Actin Reorganization
J. Biol. Chem. 2000 275: 13126-13133. [Abstract] [Full Text] [PDF]  

Molecular Basis Of Cell and Developmental Biology:

Yoh Dobashi, Mitsuhiko Shoji, Masatoshi Kitagawa, Takashi Noguchi, and Toru Kameya

Simultaneous Suppression of cdc2 and cdk2 Activities Induces Neuronal Differentiation of PC12 Cells
J. Biol. Chem. 2000 275: 12572-12580. [Abstract] [Full Text] [PDF]  

Qiang Ma, Anthony J. Renzelli, Kimberly T. Baldwin, and James M. Antonini

Superinduction of CYP1A1 Gene Expression. REGULATION OF 2,3,7,8-TETRACHLORODIBENZO-p-DIOXIN-INDUCED DEGRADATION OF Ah RECEPTOR BY CYCLOHEXIMIDE
J. Biol. Chem. 2000 275: 12676-12683. [Abstract] [Full Text] [PDF]  

Richard W. E. Clarkson, Joanna L. Heeley, Rachel Chapman, Fabienne Aillet, Ronald T. Hay, Andrew Wyllie, and Christine J. Watson

NF-B Inhibits Apoptosis in Murine Mammary Epithelia
J. Biol. Chem. 2000 275: 12737-12742. [Abstract] [Full Text] [PDF]  

Rafael Fernández-Chacón, Mircea Achiriloaie, Roger Janz, Joseph P. Albanesi, and Thomas C. Südhof

SCAMP1 Function in Endocytosis
J. Biol. Chem. 2000 275: 12752-12756. [Abstract] [Full Text] [PDF]  

Frank Beier, Allison C. Taylor, and Phyllis LuValle

Activating Transcription Factor 2 Is Necessary for Maximal Activity and Serum Induction of the Cyclin A Promoter in Chondrocytes
J. Biol. Chem. 2000 275: 12948-12953. [Abstract] [Full Text] [PDF]  

Guillaume Mitta, Franck Vandenbulcke, Florence Hubert, Michel Salzet, and Philippe Roch

Involvement of Mytilins in Mussel Antimicrobial Defense
J. Biol. Chem. 2000 275: 12954-12962. [Abstract] [Full Text] [PDF]  

Jianrong Li, Sufang Yang, and Timothy R. Billiar

Cyclic Nucleotides Suppress Tumor Necrosis Factor -Mediated Apoptosis by Inhibiting Caspase Activation and Cytochrome c Release in Primary Hepatocytes via a Mechanism Independent of Akt Activation
J. Biol. Chem. 2000 275: 13026-13034. [Abstract] [Full Text] [PDF]  

Xiuwen Tang, C. Peter Downes, Anthony D. Whetton, and P. Jane Owen-Lynch

Role of Phosphatidylinositol 3-Kinase and Specific Protein Kinase B Isoforms in the Suppression of Apoptosis Mediated by the Abelson Protein-tyrosine Kinase
J. Biol. Chem. 2000 275: 13142-13148. [Abstract] [Full Text] [PDF]  

Diying Yao, Jules J. E. Doré, Jr., and Edward B. Leof

FKBP12 Is a Negative Regulator of Transforming Growth Factor- Receptor Internalization
J. Biol. Chem. 2000 275: 13149-13154. [Abstract] [Full Text] [PDF]  

Additions and Corrections:

Angels Almenar-Queralt, Andria Lee, Catharine A. Conley, Lluis de Ribas de Pouplana, and Velia M. Fowler

Identification of a novel tropomodulin isoform, skeletal tropomodulin, that caps actin filament pointed ends in fast skeletal muscle.
J. Biol. Chem. 2000 275: 13164. [Full Text] [PDF]  

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