Minireviews:

Deborah A. Brown and Erwin London

Structure and Function of Sphingolipid- and Cholesterol-rich Membrane Rafts
J. Biol. Chem. 2000 275: 17221-17224. First Published on April 18, 2000; 10.1074/jbc.R000005200 [Full Text] [PDF]  

Accelerated Publications:

Kathleen M. Murphy, Uldis N. Streips, and Richard B. Lock

Bcl-2 Inhibits a Fas-induced Conformational Change in the Bax N Terminus and Bax Mitochondrial Translocation
J. Biol. Chem. 2000 275: 17225-17228. First Published on April 4, 2000; 10.1074/jbc.C900590199 [Abstract] [Full Text] [PDF]  

Namjin Chung, Gary Jenkins, Yusuf A. Hannun, Joseph Heitman, and Lina M. Obeid

Sphingolipids Signal Heat Stress-induced Ubiquitin-dependent Proteolysis
J. Biol. Chem. 2000 275: 17229-17232. First Published on April 10, 2000; 10.1074/jbc.C000229200 [Abstract] [Full Text] [PDF]  

Kazuhiro Kimura, Takahiro Tsuji, Yuka Takada, Toru Miki, and Shuh Narumiya

Accumulation of GTP-bound RhoA during Cytokinesis and a Critical Role of ECT2 in This Accumulation
J. Biol. Chem. 2000 275: 17233-17236. First Published on April 12, 2000; 10.1074/jbc.C000212200 [Abstract] [Full Text] [PDF]  

Xiangao Sun, Pradip Majumder, Hisashi Shioya, Frank Wu, Shailendra Kumar, Ralph Weichselbaum, Surender Kharbanda, and Donald Kufe

Activation of the Cytoplasmic c-Abl Tyrosine Kinase by Reactive Oxygen Species
J. Biol. Chem. 2000 275: 17237-17240. First Published on April 18, 2000; 10.1074/jbc.C000099200 [Abstract] [Full Text] [PDF]  

DNA: Replication Repair and Recombination:

Klaus Weisshart, Hella Förster, Elisabeth Kremmer, Bernhard Schlott, Frank Grosse, and Heinz-Peter Nasheuer

Protein-Protein Interactions of the Primase Subunits p58 and p48 with Simian Virus 40 T Antigen Are Required for Efficient Primer Synthesis in a Cell-free System
J. Biol. Chem. 2000 275: 17328-17337. First Published on March 22, 2000; 10.1074/jbc.M000717200 [Abstract] [Full Text] [PDF]  

Xiluo Chen, Shaojun Zuo, Zvi Kelman, Mike O'Donnell, Jerard Hurwitz, and Myron F. Goodman

Fidelity of Eucaryotic DNA Polymerase  Holoenzyme from Schizosaccharomyces pombe
J. Biol. Chem. 2000 275: 17677-17682. First Published on March 23, 2000; 10.1074/jbc.M910278199 [Abstract] [Full Text] [PDF]  

Nancy Matton, Josephine Simonetti, and Kandace Williams

Identification of Mismatch Repair Protein Complexes in HeLa Nuclear Extracts and Their Interaction with Heteroduplex DNA
J. Biol. Chem. 2000 275: 17808-17813. First Published on March 29, 2000; 10.1074/jbc.M909794199 [Abstract] [Full Text] [PDF]  

Genes: Structure and Regulation:

Sanjaya Singh, Christine M. Stellrecht, Hank K. Tang, and Grady F. Saunders

Modulation of PAX6 Homeodomain Function by the Paired Domain
J. Biol. Chem. 2000 275: 17306-17313. First Published on March 27, 2000; 10.1074/jbc.M000359200 [Abstract] [Full Text] [PDF]  

Catherine Galdemard, Hidehisa Yamagata, Olivier Brison, and Christian Lavialle

Regulation of FGF-3 Gene Expression in Tumorigenic and Non-tumorigenic Clones of a Human Colon Carcinoma Cell Line
J. Biol. Chem. 2000 275: 17364-17373. First Published on April 3, 2000; 10.1074/jbc.M909316199 [Abstract] [Full Text] [PDF]  

Davide Girotto, Carla Fabbro, Paola Braghetta, Paola Vitale, Dino Volpin, and Giorgio M. Bressan

Analysis of Transcription of the Col6a1 Gene in a Specific Set of Tissues Suggests a New Variant of Enhancer Region
J. Biol. Chem. 2000 275: 17381-17390. First Published on March 27, 2000; 10.1074/jbc.M000075200 [Abstract] [Full Text] [PDF]  

Joseph C. Reese, Zhengjian Zhang, and Harsha Kurpad

Identification of a Yeast Transcription Factor IID Subunit, TSG2/TAF48
J. Biol. Chem. 2000 275: 17391-17398. First Published on April 4, 2000; 10.1074/jbc.M001635200 [Abstract] [Full Text] [PDF]  

Takahisa Ueyama, Chongxue Zhu, Yunuen M. Valenzuela, Joseph G. Suzow, and Alexandre F. R. Stewart

Identification of the Functional Domain in the Transcription Factor RTEF-1 That Mediates ₁-Adrenergic Signaling in Hypertrophied Cardiac Myocytes
J. Biol. Chem. 2000 275: 17476-17480. First Published on April 6, 2000; 10.1074/jbc.M001970200 [Abstract] [Full Text] [PDF]  

Jianzhong Wei and Elizabeth C. Theil

Identification and Characterization of the Iron Regulatory Element in the Ferritin Gene of a Plant (Soybean)
J. Biol. Chem. 2000 275: 17488-17493. First Published on March 28, 2000; 10.1074/jbc.M910334199 [Abstract] [Full Text] [PDF]  

Kathleen H. Cox, Rajendra Rai, Mackenzie Distler, Jon R. Daugherty, Jonathan A. Coffman, and Terrance G. Cooper

Saccharomyces cerevisiae GATA Sequences Function as TATA Elements during Nitrogen Catabolite Repression and When Gln3p Is Excluded from the Nucleus by Overproduction of Ure2p
J. Biol. Chem. 2000 275: 17611-17618. First Published on March 19, 2000; 10.1074/jbc.M001648200 [Abstract] [Full Text] [PDF]  

Ian D'Souza and Gerard David Schellenberg

Determinants of 4-Repeat Tau Expression. COORDINATION BETWEEN ENHANCING AND INHIBITORY SPLICING SEQUENCES FOR EXON 10 INCLUSION
J. Biol. Chem. 2000 275: 17700-17709. First Published on March 29, 2000; 10.1074/jbc.M909470199 [Abstract] [Full Text] [PDF]  

Andrei Chabes and Lars Thelander

Controlled Protein Degradation Regulates Ribonucleotide Reductase Activity in Proliferating Mammalian Cells during the Normal Cell Cycle and in Response to DNA Damage and Replication Blocks
J. Biol. Chem. 2000 275: 17747-17753. First Published on March 23, 2000; 10.1074/jbc.M000799200 [Abstract] [Full Text] [PDF]  

Christy J. Fryer, H. Karimi Kinyamu, Inez Rogatsky, Michael J. Garabedian, and Trevor K. Archer

Selective Activation of the Glucocorticoid Receptor by Steroid Antagonists in Human Breast Cancer and Osteosarcoma Cells
J. Biol. Chem. 2000 275: 17771-17777. First Published on March 31, 2000; 10.1074/jbc.M908729199 [Abstract] [Full Text] [PDF]  

Antonio del Castillo-Olivares and Gregorio Gil

₁-Fetoprotein Transcription Factor Is Required for the Expression of Sterol 12-Hydroxylase, the Specific Enzyme for Cholic Acid Synthesis. POTENTIAL ROLE IN THE BILE ACID-MEDIATED REGULATION OF GENE TRANSCRIPTION
J. Biol. Chem. 2000 275: 17793-17799. First Published on March 30, 2000; 10.1074/jbc.M000996200 [Abstract] [Full Text] [PDF]  

David Yeagley, Jonathan Moll, Charles A. Vinson, and Patrick G. Quinn

Characterization of Elements Mediating Regulation of Phosphoenolpyruvate Carboxykinase Gene Transcription by Protein Kinase A and Insulin. IDENTIFICATION OF A DISTINCT COMPLEX FORMED IN CELLS THAT MEDIATE INSULIN INHIBITION
J. Biol. Chem. 2000 275: 17814-17820. First Published on March 28, 2000; 10.1074/jbc.M909842199 [Abstract] [Full Text] [PDF]  

RNA: Structure Metabolism and Catalysis:

Akiko Tabuchi, Ryuki Nakaoka, Kenji Amano, Masaru Yukimine, Tsugunobu Andoh, Yasushi Kuraishi, and Masaaki Tsuda

Differential Activation of Brain-derived Neurotrophic Factor Gene Promoters I and III by Ca²⁺ Signals Evoked via L-type Voltage-dependent and N-Methyl-D-aspartate Receptor Ca²⁺ Channels
J. Biol. Chem. 2000 275: 17269-17275. First Published on March 22, 2000; 10.1074/jbc.M909538199 [Abstract] [Full Text] [PDF]  

Chaoping Chen, Sitong Sheng, Zhifeng Shao, and Peixuan Guo

A Dimer as a Building Block in Assembling RNA. A HEXAMER THAT GEARS BACTERIAL VIRUS phi29 DNA-TRANSLOCATING MACHINERY
J. Biol. Chem. 2000 275: 17510-17516. First Published on March 13, 2000; 10.1074/jbc.M909662199 [Abstract] [Full Text] [PDF]  

Jong-Won Oh, Gwo-Tarng Sheu, and Michael M. C. Lai

Template Requirement and Initiation Site Selection by Hepatitis C Virus Polymerase on a Minimal Viral RNA Template
J. Biol. Chem. 2000 275: 17710-17717. First Published on April 3, 2000; 10.1074/jbc.M908781199 [Abstract] [Full Text] [PDF]  

Wi S. Lai, Ester Carballo, Judith M. Thorn, Elizabeth A. Kennington, and Perry J. Blackshear

Interactions of CCCH Zinc Finger Proteins with mRNA. BINDING OF TRISTETRAPROLIN-RELATED ZINC FINGER PROTEINS TO AU-RICH ELEMENTS AND DESTABILIZATION OF mRNA
J. Biol. Chem. 2000 275: 17827-17837. First Published on April 5, 2000; 10.1074/jbc.M001696200 [Abstract] [Full Text] [PDF]  

Protein Synthesis Post-Translation Modification and Degradation:

Marjan E. Askarian-Amiri, Herman J. Pel, Diane Guévremont, Kim K. McCaughan, Elizabeth S. Poole, Vicki G. Sumpter, and Warren P. Tate

Functional Characterization of Yeast Mitochondrial Release Factor 1
J. Biol. Chem. 2000 275: 17241-17248. First Published on March 22, 2000; 10.1074/jbc.M910448199 [Abstract] [Full Text] [PDF]  

Mikhail M. Pooggin, Thomas Hohn, and Johannes Fütterer

Role of a Short Open Reading Frame in Ribosome Shunt on the Cauliflower Mosaic Virus RNA Leader
J. Biol. Chem. 2000 275: 17288-17296. First Published on March 27, 2000; 10.1074/jbc.M001143200 [Abstract] [Full Text] [PDF]  

IngMarie Nilsson and Gunnar von Heijne

Glycosylation Efficiency of Asn-Xaa-Thr Sequons Depends Both on the Distance from the C Terminus and on the Presence of a Downstream Transmembrane Segment
J. Biol. Chem. 2000 275: 17338-17343. First Published on March 22, 2000; 10.1074/jbc.M002317200 [Abstract] [Full Text] [PDF]  

Andrew T. Bender, Damon R. Demady, and Yoichi Osawa

Ubiquitination of Neuronal Nitric-oxide Synthase in Vitro and in Vivo
J. Biol. Chem. 2000 275: 17407-17411. First Published on April 5, 2000; 10.1074/jbc.M000155200 [Abstract] [Full Text] [PDF]  

Hanh Le, Karen S. Browning, and Daniel R. Gallie

The Phosphorylation State of Poly(A)-binding Protein Specifies Its Binding to Poly(A) RNA and Its Interaction with Eukaryotic Initiation Factor (eIF) 4F, eIFiso4F, and eIF4B
J. Biol. Chem. 2000 275: 17452-17462. First Published on March 24, 2000; 10.1074/jbc.M001186200 [Abstract] [Full Text] [PDF]  

Martin O. Bergo, Gordon K. Leung, Patricia Ambroziak, James C. Otto, Patrick J. Casey, and Stephen G. Young

Targeted Inactivation of the Isoprenylcysteine Carboxyl Methyltransferase Gene Causes Mislocalization of K-Ras in Mammalian Cells
J. Biol. Chem. 2000 275: 17605-17610. First Published on March 19, 2000; 10.1074/jbc.C000079200 [Abstract] [Full Text] [PDF]  

Markus W. Ribbe, Evan H. Bursey, and Barbara K. Burgess

Identification of an Fe protein Residue (Glu¹⁴⁶) of Azotobacter vinelandii Nitrogenase That Is Specifically Involved in FeMo Cofactor Insertion
J. Biol. Chem. 2000 275: 17631-17638. First Published ; 10.1074/jbc.275.23.17631 [Abstract] [Full Text] [PDF]  

Xiping Bi and Dixie J. Goss

Wheat Germ Poly(A)-binding Protein Increases the ATPase and the RNA Helicase Activity of Translation Initiation Factors eIF4A, eIF4B, and eIF-iso4F
J. Biol. Chem. 2000 275: 17740-17746. First Published on March 15, 2000; 10.1074/jbc.M909464199 [Abstract] [Full Text] [PDF]  

Jae Ryoung Hwang, Daria E. Siekhaus, Robert S. Fuller, Paul H. Taghert, and Iris Lindberg

Interaction of Drosophila melanogaster Prohormone Convertase 2 and 7B2. INSECT CELL-SPECIFIC PROCESSING AND SECRETION
J. Biol. Chem. 2000 275: 17886-17893. First Published on April 3, 2000; 10.1074/jbc.M000032200 [Abstract] [Full Text] [PDF]  

Genomics Proteomics and Bioinformatics:

Francesc Posas, James R. Chambers, John A. Heyman, James P. Hoeffler, Eulalia de Nadal, and Joaquín Ariño

The Transcriptional Response of Yeast to Saline Stress
J. Biol. Chem. 2000 275: 17249-17255. First Published on March 9, 2000; 10.1074/jbc.M910016199 [Abstract] [Full Text] [PDF]  

Shawn M. Lawrence, Kathleen A. Huddleston, Lee R. Pitts, Nam Nguyen, Yuan C. Lee, Willie F. Vann, Timothy A. Coleman, and Michael J. Betenbaugh

Cloning and Expression of the Human N-Acetylneuraminic Acid Phosphate Synthase Gene with 2-Keto-3-deoxy-D-glycero- D-galacto-nononic Acid Biosynthetic Ability
J. Biol. Chem. 2000 275: 17869-17877. First Published on April 3, 2000; 10.1074/jbc.M000217200 [Abstract] [Full Text] [PDF]  

Protein Structure and Folding:

Roy E. Weber, Angela Fago, Adalberto L. Val, Anny Bang, Marie-Louise Van Hauwaert, Sylvia Dewilde, Franck Zal, and Luc Moens

Isohemoglobin Differentiation in the Bimodal-breathing Amazon Catfish Hoplosternum littorale
J. Biol. Chem. 2000 275: 17297-17305. First Published on March 27, 2000; 10.1074/jbc.M001209200 [Abstract] [Full Text] [PDF]  

Uwe Schlattner and Theo Wallimann

Octamers of Mitochondrial Creatine Kinase Isoenzymes Differ in Stability and Membrane Binding
J. Biol. Chem. 2000 275: 17314-17320. First Published on March 28, 2000; 10.1074/jbc.M001919200 [Abstract] [Full Text] [PDF]  

J. Nicholas Maiorano and W. Sean Davidson

The Orientation of Helix 4 in Apolipoprotein A-I-containing Reconstituted High Density Lipoproteins
J. Biol. Chem. 2000 275: 17374-17380. First Published on April 4, 2000; 10.1074/jbc.M000044200 [Abstract] [Full Text] [PDF]  

Bruno Collinet, Mireille Hervé, Frédéric Pecorari, Philippe Minard, Olivier Eder, and Michel Desmadril

Functionally Accepted Insertions of Proteins within Protein Domains
J. Biol. Chem. 2000 275: 17428-17433. First Published on March 27, 2000; 10.1074/jbc.M000666200 [Abstract] [Full Text] [PDF]  

Tony A. Klink and Ronald T. Raines

Conformational Stability Is a Determinant of Ribonuclease A Cytotoxicity
J. Biol. Chem. 2000 275: 17463-17467. First Published on March 27, 2000; 10.1074/jbc.M001132200 [Abstract] [Full Text] [PDF]  

Rico Laage, Jan Rohde, Bettina Brosig, and Dieter Langosch

A Conserved Membrane-spanning Amino Acid Motif Drives Homomeric and Supports Heteromeric Assembly of Presynaptic SNARE Proteins
J. Biol. Chem. 2000 275: 17481-17487. First Published on April 11, 2000; 10.1074/jbc.M910092199 [Abstract] [Full Text] [PDF]  

Grace C. Chu, Koki Katakura, Takeshi Tomita, Xuhong Zhang, Danyu Sun, Michihiko Sato, Masanao Sasahara, Takamasa Kayama, Masao Ikeda-Saito, and Tadashi Yoshida

Histidine 20, the Crucial Proximal Axial Heme Ligand of Bacterial Heme Oxygenase Hmu O from Corynebacterium diphtheriae
J. Biol. Chem. 2000 275: 17494-17500. First Published on April 5, 2000; 10.1074/jbc.M000830200 [Abstract] [Full Text] [PDF]  

Mark A. Hink, Remko A. Griep, Jan Willem Borst, Arie van Hoek, Michel H. M. Eppink, Arjen Schots, and Antonie J. W. G. Visser

Structural Dynamics of Green Fluorescent Protein Alone and Fused with a Single Chain Fv Protein
J. Biol. Chem. 2000 275: 17556-17560. First Published on March 15, 2000; 10.1074/jbc.M001348200 [Abstract] [Full Text] [PDF]  

Peer R. E. Mittl, Lucas Lüthy, Peter Hunziker, and Markus G. Grütter

The Cysteine-rich Protein A from Helicobacter pylori Is a -Lactamase
J. Biol. Chem. 2000 275: 17693-17699. First Published on March 27, 2000; 10.1074/jbc.M001869200 [Abstract] [Full Text] [PDF]  

Kelly A. Hogan, Oleg V. Gorkun, Karim C. Lounes, Andrew I. Coates, John W. Weisel, Roy R. Hantgan, and Susan T. Lord

Recombinant Fibrinogen Vlissingen/Frankfurt IV. THE DELETION OF RESIDUES 319 AND 320 FROM THE  CHAIN OF FIBRINOGEN ALTERS CALCIUM BINDING, FIBRIN POLYMERIZATION, CROSS-LINKING, AND PLATELET AGGREGATION
J. Biol. Chem. 2000 275: 17778-17785. First Published on March 30, 2000; 10.1074/jbc.M001618200 [Abstract] [Full Text] [PDF]  

Laura L. Kirkpatrick, Martin M. Matzuk, D'Nette C. Dodds, and Mark S. Perin

Biochemical Interactions of the Neuronal Pentraxins. NEURONAL PENTRAXIN (NP) RECEPTOR BINDS TO TAIPOXIN AND TAIPOXIN-ASSOCIATED CALCIUM-BINDING PROTEIN 49 VIA NP1 AND NP2
J. Biol. Chem. 2000 275: 17786-17792. First Published on March 28, 2000; 10.1074/jbc.M002254200 [Abstract] [Full Text] [PDF]  

Andrew J. Ramsey, Lance C. Russell, Sherry R. Whitt, and Michael Chinkers

Overlapping Sites of Tetratricopeptide Repeat Protein Binding and Chaperone Activity in Heat Shock Protein 90
J. Biol. Chem. 2000 275: 17857-17862. First Published on April 4, 2000; 10.1074/jbc.M001625200 [Abstract] [Full Text] [PDF]  

Enzyme Catalysis and Regulation:

Lidia Vasiljeva, Andres Merits, Petri Auvinen, and Leevi Kääriäinen

Identification of a Novel Function of the Alphavirus Capping Apparatus. RNA 5'-TRIPHOSPHATASE ACTIVITY OF Nsp2
J. Biol. Chem. 2000 275: 17281-17287. First Published on March 23, 2000; 10.1074/jbc.M910340199 [Abstract] [Full Text] [PDF]  

Husam M. Abu-Soud, Koji Ichimori, Anthony Presta, and Dennis J. Stuehr

Electron Transfer, Oxygen Binding, and Nitric Oxide Feedback Inhibition in Endothelial Nitric-oxide Synthase
J. Biol. Chem. 2000 275: 17349-17357. First Published on April 3, 2000; 10.1074/jbc.M000050200 [Abstract] [Full Text] [PDF]  

Annong Huang, Joseph A. Vita, Richard C. Venema, and John F. Keaney, Jr.

Ascorbic Acid Enhances Endothelial Nitric-oxide Synthase Activity by Increasing Intracellular Tetrahydrobiopterin
J. Biol. Chem. 2000 275: 17399-17406. First Published on April 3, 2000; 10.1074/jbc.M002248200 [Abstract] [Full Text] [PDF]  

Subrata Adak, Qian Wang, and Dennis J. Stuehr

Molecular Basis for Hyperactivity in Tryptophan 409 Mutants of Neuronal NO Synthase
J. Biol. Chem. 2000 275: 17434-17439. First Published on March 31, 2000; 10.1074/jbc.M000846200 [Abstract] [Full Text] [PDF]  

Brenda S. Nieslanik and William M. Atkins

The Catalytic Tyr-9 of Glutathione S-Transferase A1-1 Controls the Dynamics of the C terminus
J. Biol. Chem. 2000 275: 17447-17451. First Published on April 5, 2000; 10.1074/jbc.M002083200 [Abstract] [Full Text] [PDF]  

Wolfram Weckwerth, Koichi Miyamoto, Katsuhura Iinuma, Martin Krause, Mirko Glinski, Thomas Storm, Gerd Bonse, Horst Kleinkauf, and Rainer Zocher

Biosynthesis of PF1022A and Related Cyclooctadepsipeptides
J. Biol. Chem. 2000 275: 17909-17915. First Published on April 4, 2000; 10.1074/jbc.M001084200 [Abstract] [Full Text] [PDF]  

Metabolism and Bioenergetics:

Laurent Cournac, Kevin Redding, Jacques Ravenel, Dominique Rumeau, Eve-Marie Josse, Marcel Kuntz, and Gilles Peltier

Electron Flow between Photosystem II and Oxygen in Chloroplasts of Photosystem I-deficient Algae Is Mediated by a Quinol Oxidase Involved in Chlororespiration
J. Biol. Chem. 2000 275: 17256-17262. First Published on March 22, 2000; 10.1074/jbc.M908732199 [Abstract] [Full Text] [PDF]  

Jegatheesan Seharaseyon, Norihito Sasaki, Andreas Ohler, Toshiaki Sato, Heather Fraser, David C. Johns, Brian O'Rourke, and Eduardo Marbán

Evidence against Functional Heteromultimerization of the K_ATP Channel Subunits Kir6.1 and Kir6.2
J. Biol. Chem. 2000 275: 17561-17565. First Published ; 10.1074/jbc.275.23.17561 [Abstract] [Full Text] [PDF]  

Derek T. McLachlin, Angela M. Coveny, Sonya M. Clark, and Stanley D. Dunn

Site-directed Cross-linking of b to the , , and a Subunits of the Escherichia coli ATP Synthase
J. Biol. Chem. 2000 275: 17571-17577. First Published on March 24, 2000; 10.1074/jbc.M000375200 [Abstract] [Full Text] [PDF]  

Salvatore Scacco, Rosaria Vergari, Richard C. Scarpulla, Zuzana Technikova-Dobrova, Annamaria Sardanelli, Rossana Lambo, Vito Lorusso, and Sergio Papa

cAMP-dependent Phosphorylation of the Nuclear Encoded 18-kDa (IP) Subunit of Respiratory Complex I and Activation of the Complex in Serum-starved Mouse Fibroblast Cultures
J. Biol. Chem. 2000 275: 17578-17582. First Published on March 22, 2000; 10.1074/jbc.M001174200 [Abstract] [Full Text] [PDF]  

Jürgen Illerhaus, Lothar Altschmied, Jan Reichert, Elena Zak, Reinhold G. Herrmann, and Wolfgang Haehnel

Dynamic Interaction of Plastocyanin with the Cytochrome bf Complex
J. Biol. Chem. 2000 275: 17590-17595. First Published ; 10.1074/jbc.275.23.17590 [Abstract] [Full Text] [PDF]  

Glycobiology and Extracellular Matrices:

Anne Imberty, Catherine Gautier, Julien Lescar, Serge Pérez, Lode Wyns, and Remy Loris

An Unusual Carbohydrate Binding Site Revealed by the Structures of Two Maackia amurensis Lectins Complexed with Sialic Acid-containing Oligosaccharides
J. Biol. Chem. 2000 275: 17541-17548. First Published on March 15, 2000; 10.1074/jbc.M000560200 [Abstract] [Full Text] [PDF]  

Shari A. Price-Schiavi, Xiaoyun Zhu, Ronny Aquinin, and Kermit L. Carraway

Sialomucin Complex (Rat Muc4) Is Regulated by Transforming Growth Factor  in Mammary Gland by a Novel Post-translational Mechanism
J. Biol. Chem. 2000 275: 17800-17807. First Published ; 10.1074/jbc.275.23.17800 [Abstract] [Full Text] [PDF]  

Lipids and Lipoproteins:

Jose L. Soulages and Estela L. Arrese

Dynamics and Hydration of the -Helices of Apolipophorin III
J. Biol. Chem. 2000 275: 17501-17509. First Published on March 9, 2000; 10.1074/jbc.M909661199 [Abstract] [Full Text] [PDF]  

Diana M. Shih, Yu-Rong Xia, Xu-Ping Wang, Elizabeth Miller, Lawrence W. Castellani, Ganesamoorthy Subbanagounder, Hilde Cheroutre, Kym F. Faull, Judith A. Berliner, Joseph L. Witztum, and Aldons J. Lusis

Combined Serum Paraoxonase Knockout/Apolipoprotein E Knockout Mice Exhibit Increased Lipoprotein Oxidation and Atherosclerosis
J. Biol. Chem. 2000 275: 17527-17535. First Published on March 28, 2000; 10.1074/jbc.M910376199 [Abstract] [Full Text] [PDF]  

Michele Mietus-Snyder, Maya S. Gowri, and Robert E. Pitas

Class A Scavenger Receptor Up-regulation in Smooth Muscle Cells by Oxidized Low Density Lipoprotein. ENHANCEMENT BY CALCIUM FLUX AND CONCURRENT CYCLOOXYGENASE-2 UP-REGULATION
J. Biol. Chem. 2000 275: 17661-17670. First Published ; 10.1074/jbc.275.23.17661 [Abstract] [Full Text] [PDF]  

Membrane Transport Structure Function and Biogenesis:

Hyoweon Bang, Yangmi Kim, and Donghee Kim

TREK-2, a New Member of the Mechanosensitive Tandem-pore K⁺ Channel Family
J. Biol. Chem. 2000 275: 17412-17419. First Published on March 31, 2000; 10.1074/jbc.M000445200 [Abstract] [Full Text] [PDF]  

Yvonne Lange, Jin Ye, Mike Rigney, and Theodore Steck

Cholesterol Movement in Niemann-Pick Type C Cells and in Cells Treated with Amphiphiles
J. Biol. Chem. 2000 275: 17468-17475. First Published on April 4, 2000; 10.1074/jbc.M000875200 [Abstract] [Full Text] [PDF]  

Noboru Mitsuhashi, Takashi Miki, Hiroshi Senbongi, Norihide Yokoi, Hideki Yano, Masaru Miyazaki, Nobuyuki Nakajima, Toshihiko Iwanaga, Yuji Yokoyama, Takehiko Shibata, and Susumu Seino

MTABC3, a Novel Mitochondrial ATP-binding Cassette Protein Involved in Iron Homeostasis
J. Biol. Chem. 2000 275: 17536-17540. First Published ; 10.1074/jbc.275.23.17536 [Abstract] [Full Text] [PDF] Supplemental Data  

Akiko Eguchi, Toru Kondoh, Hirokazu Kosaka, Takashi Suzuki, Hiroshi Momota, Akinori Masago, Tetsuya Yoshida, Hideharu Taira, Akiko Ishii-Watabe, Jun Okabe, Jianhong Hu, Naoyuki Miura, Shigeharu Ueda, Yasuo Suzuki, Takao Taki, Takao Hayakawa, and Mahito Nakanishi

Identification and Characterization of Cell Lines with a Defect in a Post-adsorption Stage of Sendai Virus-mediated Membrane Fusion
J. Biol. Chem. 2000 275: 17549-17555. First Published on March 27, 2000; 10.1074/jbc.M910004199 [Abstract] [Full Text] [PDF]  

Vladimir I. Slepnev, Gian-Carlo Ochoa, Margaret H. Butler, and Pietro De Camilli

Tandem Arrangement of the Clathrin and AP-2 Binding Domains in Amphiphysin 1 and Disruption of Clathrin Coat Function by Amphiphysin Fragments Comprising These Sites
J. Biol. Chem. 2000 275: 17583-17589. First Published on March 15, 2000; 10.1074/jbc.M910430199 [Abstract] [Full Text] [PDF]  

Koh Nagata, Masahito Nishitani, Michinori Matsuo, Noriyuki Kioka, Teruo Amachi, and Kazumitsu Ueda

Nonequivalent Nucleotide Trapping in the Two Nucleotide Binding Folds of the Human Multidrug Resistance Protein MRP1
J. Biol. Chem. 2000 275: 17626-17630. First Published on March 29, 2000; 10.1074/jbc.M000792200 [Abstract] [Full Text] [PDF]  

Yvonne M. Kobayashi, Badr A. Alseikhan, and Larry R. Jones

Localization and Characterization of the Calsequestrin-binding Domain of Triadin 1. EVIDENCE FOR A CHARGED -STRAND IN MEDIATING THE PROTEIN-PROTEIN INTERACTION
J. Biol. Chem. 2000 275: 17639-17646. First Published on March 30, 2000; 10.1074/jbc.M002091200 [Abstract] [Full Text] [PDF]  

Xiao-Dong Gao and Neta Dean

Distinct Protein Domains of the Yeast Golgi GDP-mannose Transporter Mediate Oligomer Assembly and Export from the Endoplasmic Reticulum
J. Biol. Chem. 2000 275: 17718-17727. First Published on March 27, 2000; 10.1074/jbc.M909946199 [Abstract] [Full Text] [PDF]  

Olivier Maudoux, Henri Batoko, Claudia Oecking, Kris Gevaert, Joel Vandekerckhove, Marc Boutry, and Pierre Morsomme

A Plant Plasma Membrane H⁺-ATPase Expressed in Yeast Is Activated by Phosphorylation at Its Penultimate Residue and Binding of 14-3-3 Regulatory Proteins in the Absence of Fusicoccin
J. Biol. Chem. 2000 275: 17762-17770. First Published on March 23, 2000; 10.1074/jbc.M909690199 [Abstract] [Full Text] [PDF]  

Marko Suokas, Raili Myllylä, and Sakari Kellokumpu

A Single C-terminal Peptide Segment Mediates Both Membrane Association and Localization of Lysyl Hydroxylase in the Endoplasmic Reticulum
J. Biol. Chem. 2000 275: 17863-17868. First Published on March 29, 2000; 10.1074/jbc.M908025199 [Abstract] [Full Text] [PDF]  

Hironori Higashio, Yukio Kimata, Toshio Kiriyama, Aiko Hirata, and Kenji Kohno

Sfb2p, a Yeast Protein Related to Sec24p, Can Function as a Constituent of COPII Coats Required for Vesicle Budding from the Endoplasmic Reticulum
J. Biol. Chem. 2000 275: 17900-17908. First Published on April 3, 2000; 10.1074/jbc.M000751200 [Abstract] [Full Text] [PDF]  

Mechanisms Of Signal Transduction:

Ramesh K. Ganju, Stephanie A. Brubaker, Rebecca D. Chernock, Shalom Avraham, and Jerome E. Groopman

-Chemokine Receptor CCR5 Signals through SHP1, SHP2, and Syk
J. Biol. Chem. 2000 275: 17263-17268. First Published on March 23, 2000; 10.1074/jbc.M000689200 [Abstract] [Full Text] [PDF]  

H. Rosie Xing, Jose Lozano, and Richard Kolesnick

Epidermal Growth Factor Treatment Enhances the Kinase Activity of Kinase Suppressor of Ras
J. Biol. Chem. 2000 275: 17276-17280. First Published on April 10, 2000; 10.1074/jbc.C900989199 [Abstract] [Full Text] [PDF]  

Céline Galés, Aline Kowalski-Chauvel, Marie Noelle Dufour, Catherine Seva, Luis Moroder, Lucien Pradayrol, Nicole Vaysse, Daniel Fourmy, and Sandrine Silvente-Poirot

Mutation of Asn-391 within the Conserved NPXXY Motif of the Cholecystokinin B Receptor Abolishes G_q Protein Activation without Affecting Its Association with the Receptor
J. Biol. Chem. 2000 275: 17321-17327. First Published on March 27, 2000; 10.1074/jbc.M909801199 [Abstract] [Full Text] [PDF]  

Delphine Courilleau, Eric Chastre, Michèle Sabbah, Gérard Redeuilh, Azeddine Atfi, and Jan Mester

B-ind1, a Novel Mediator of Rac1 Signaling Cloned from Sodium Butyrate-treated Fibroblasts
J. Biol. Chem. 2000 275: 17344-17348. First Published on March 28, 2000; 10.1074/jbc.M000887200 [Abstract] [Full Text] [PDF]  

Jonathan C. Poe, Manabu Fujimoto, Paul J. Jansen, Ann S. Miller, and Thomas F. Tedder

CD22 Forms a Quaternary Complex with SHIP, Grb2, and Shc. A PATHWAY FOR REGULATION OF B LYMPHOCYTE ANTIGEN RECEPTOR-INDUCED CALCIUM FLUX
J. Biol. Chem. 2000 275: 17420-17427. First Published on March 31, 2000; 10.1074/jbc.M001892200 [Abstract] [Full Text] [PDF]  

Ming-jiang Xu, Runxiang Zhao, and Zhizhuang Joe Zhao

Identification and Characterization of Leukocyte-associated Ig-like Receptor-1 as a Major Anchor Protein of Tyrosine Phosphatase SHP-1 in Hematopoietic Cells
J. Biol. Chem. 2000 275: 17440-17446. First Published on April 10, 2000; 10.1074/jbc.M001313200 [Abstract] [Full Text] [PDF]  

Michael Schaefer, Timothy D. Plant, Alexander G. Obukhov, Thomas Hofmann, Thomas Gudermann, and Günter Schultz

Receptor-mediated Regulation of the Nonselective Cation Channels TRPC4 and TRPC5
J. Biol. Chem. 2000 275: 17517-17526. First Published ; 10.1074/jbc.275.23.17517 [Abstract] [Full Text] [PDF]  

Jun Mukai, Takahisa Hachiya, Shisako Shoji-Hoshino, Makoto T. Kimura, Daita Nadano, Petro Suvanto, Takaomi Hanaoka, Yin Li, Shinji Irie, Lloyd A. Greene, and Taka-Aki Sato

NADE, a p75NTR-associated Cell Death Executor, Is Involved in Signal Transduction Mediated by the Common Neurotrophin Receptor p75NTR
J. Biol. Chem. 2000 275: 17566-17570. First Published on April 11, 2000; 10.1074/jbc.C000140200 [Abstract] [Full Text] [PDF]  

Toril Bremnes, Joachim D. Paasche, Anja Mehlum, Cecilie Sandberg, Bjørn Bremnes, and Håvard Attramadal

Regulation and Intracellular Trafficking Pathways of the Endothelin Receptors
J. Biol. Chem. 2000 275: 17596-17604. First Published on March 30, 2000; 10.1074/jbc.M000142200 [Abstract] [Full Text] [PDF]  

Naoki Kimura, Ritsuko Matsuo, Hiroshi Shibuya, Kinichi Nakashima, and Tetsuya Taga

BMP2-induced Apoptosis Is Mediated by Activation of the TAK1-p38 Kinase Pathway That Is Negatively Regulated by Smad6
J. Biol. Chem. 2000 275: 17647-17652. First Published on March 23, 2000; 10.1074/jbc.M908622199 [Abstract] [Full Text] [PDF]  

Tomoichiro Asano, Akira Kanda, Hideki Katagiri, Masao Nawano, Takehide Ogihara, Kouichi Inukai, Motonobu Anai, Yasushi Fukushima, Yoshio Yazaki, Masatoshi Kikuchi, Roya Hooshmand-Rad, Carl-Henrik Heldin, Yoshitomo Oka, and Makoto Funaki

p110 Is Up-regulated during Differentiation of 3T3-L1 Cells and Contributes to the Highly Insulin-responsive Glucose Transport Activity
J. Biol. Chem. 2000 275: 17671-17676. First Published on March 16, 2000; 10.1074/jbc.M910391199 [Abstract] [Full Text] [PDF]  

Eyleen L. K. Goh, Tao Zhu, Shoshana Yakar, Derek LeRoith, and Peter E. Lobie

CrkII Participation in the Cellular Effects of Growth Hormone and Insulin-like Growth Factor-1. PHOSPHATIDYLINOSITOL-3 KINASE DEPENDENT AND INDEPENDENT EFFECTS
J. Biol. Chem. 2000 275: 17683-17692. First Published on March 23, 2000; 10.1074/jbc.M001972200 [Abstract] [Full Text] [PDF]  

Mausumee Guha, Wei Bai, Jerry L. Nadler, and Rama Natarajan

Molecular Mechanisms of Tumor Necrosis Factor  Gene Expression in Monocytic Cells via Hyperglycemia-induced Oxidant Stress-dependent and -independent Pathways
J. Biol. Chem. 2000 275: 17728-17739. First Published ; 10.1074/jbc.275.23.17728 [Abstract] [Full Text] [PDF]  

Jean-Bernard Créchet, Eric Jacquet, Alberto Bernardi, and Andrea Parmeggiani

Analysis of the Role of the Hypervariable Region of Yeast Ras2p and Its Farnesylation in the Interaction with Exchange Factors and Adenylyl Cyclase
J. Biol. Chem. 2000 275: 17754-17761. First Published on March 21, 2000; 10.1074/jbc.M000729200 [Abstract] [Full Text] [PDF]  

Anthony Makkinje, Deborah A. Quinn, Ang Chen, Carmen L. Cadilla, Thomas Force, Joseph V. Bonventre, and John M. Kyriakis

Gene 33/Mig-6, a Transcriptionally Inducible Adapter Protein That Binds GTP-Cdc42 and Activates SAPK/JNK. A POTENTIAL MARKER TRANSCRIPT FOR CHRONIC PATHOLOGIC CONDITIONS, SUCH AS DIABETIC NEPHROPATHY. POSSIBLE ROLE IN THE RESPONSE TO PERSISTENT STRESS
J. Biol. Chem. 2000 275: 17838-17847. First Published on April 3, 2000; 10.1074/jbc.M909735199 [Abstract] [Full Text] [PDF]  

Rui-Hong Chen, W. Vivianne Ding, and Frank McCormick

Wnt Signaling to -Catenin Involves Two Interactive Components. GLYCOGEN SYNTHASE KINASE-3 INHIBITION AND ACTIVATION OF PROTEIN KINASE C
J. Biol. Chem. 2000 275: 17894-17899. First Published on April 3, 2000; 10.1074/jbc.M905336199 [Abstract] [Full Text] [PDF]  

Molecular Basis Of Cell and Developmental Biology:

R. Bruce Montgomery, Junitta Guzman, Donald M. O'Rourke, and William L. Stahl

Expression of Oncogenic Epidermal Growth Factor Receptor Family Kinases Induces Paclitaxel Resistance and Alters -Tubulin Isotype Expression
J. Biol. Chem. 2000 275: 17358-17363. First Published on April 3, 2000; 10.1074/jbc.M000966200 [Abstract] [Full Text] [PDF]  

Franca Locatelli, Marcella Bracale, Flavio Magaraggia, Franco Faoro, Lucia A. Manzocchi, and Immacolata Coraggio

The Product of the Rice myb7 Unspliced mRNA Dimerizes with the Maize Leucine Zipper Opaque2 and Stimulates Its Activity in a Transient Expression Assay
J. Biol. Chem. 2000 275: 17619-17625. First Published on March 22, 2000; 10.1074/jbc.M000647200 [Abstract] [Full Text] [PDF]  

Yashomati M. Patel and M. Daniel Lane

Mitotic Clonal Expansion during Preadipocyte Differentiation: Calpain-mediated Turnover of p27
J. Biol. Chem. 2000 275: 17653-17660. First Published on April 3, 2000; 10.1074/jbc.M910445199 [Abstract] [Full Text] [PDF]  

Paula M. B. Pahl, Xiang-Dong Yan, Yvonne K. Hodges, Eli A. Rosenthal, Marcus A. Horwitz, and Lawrence D. Horwitz

An Exochelin of Mycobacterium tuberculosis Reversibly Arrests Growth of Human Vascular Smooth Muscle Cells in Vitro
J. Biol. Chem. 2000 275: 17821-17826. First Published on March 20, 2000; 10.1074/jbc.M909918199 [Abstract] [Full Text] [PDF]  

Ralph H. Kehlenbach and Larry Gerace

Phosphorylation of the Nuclear Transport Machinery Down-regulates Nuclear Protein Import in Vitro
J. Biol. Chem. 2000 275: 17848-17856. First Published on April 3, 2000; 10.1074/jbc.M001455200 [Abstract] [Full Text] [PDF]  

Ronald W. Holz, Michael D. Hlubek, Scott D. Sorensen, Stephen K. Fisher, Tamas Balla, Shoichiro Ozaki, Glenn D. Prestwich, Edward L. Stuenkel, and Mary A. Bittner

A Pleckstrin Homology Domain Specific for Phosphatidylinositol 4,5-Bisphosphate (PtdIns-4,5-P₂) and Fused to Green Fluorescent Protein Identifies Plasma Membrane PtdIns-4,5-P₂ as Being Important in Exocytosis
J. Biol. Chem. 2000 275: 17878-17885. First Published on March 28, 2000; 10.1074/jbc.M000925200 [Abstract] [Full Text] [PDF]  

Additions and Corrections:

Yohko U. Katagiri, Tetsuya Mori, Tomoko Taguchi, Tae Takeda, Nobutaka Kiyokawa, and Junichiro Fujimoto

Activation of Src family kinase Yes induced by Shiga toxin binding to globotriaosyl ceramide (Gb3/CD77) in low density, detergent-insoluble microdomains.
J. Biol. Chem. 2000 275: 17916. [Full Text] [PDF]  

Xiao-qing Gan, Ji-yong Wang, Qi-heng Yang, Zhong Li, Feng Liu, Gang Pei, and Lin Li

Interaction between the conserved region in the C-terminal domain of GRK2 and rhodopsin is necessary for GRK2 to catalyze receptor phosphorylation.
J. Biol. Chem. 2000 275: 17916. [Full Text] [PDF]  

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