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Table of Contents: Jun 23 2000; 275 (25)   [Index by Author] 
       Accelerated Publications
       DNA: Replication Repair and Recombination
       Genes: Structure and Regulation
       RNA: Structure Metabolism and Catalysis
       Protein Synthesis Post-Translation Modification and Degradation
       Genomics Proteomics and Bioinformatics
       Protein Structure and Folding
       Enzyme Catalysis and Regulation
       Metabolism and Bioenergetics
       Glycobiology and Extracellular Matrices
       Lipids and Lipoproteins
       Membrane Transport Structure Function and Biogenesis
       Mechanisms Of Signal Transduction
       Molecular Basis Of Cell and Developmental Biology
       Additions and Corrections
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Accelerated Publications:

David L. Huffman and Thomas V. O'Halloran
Energetics of Copper Trafficking between the Atx1 Metallochaperone and the Intracellular Copper Transporter, Ccc2
J. Biol. Chem. 2000 275: 18611-18614. [Abstract] [Full Text] [PDF]  

Chia-Hsin Yeh, Wen-Cheng Wang, Tsang-Tang Hsieh, and Tur-Fu Huang
Agkistin, a Snake Venom-derived Glycoprotein Ib Antagonist, Disrupts von Willebrand Factor-Endothelial Cell Interaction and Inhibits Angiogenesis
J. Biol. Chem. 2000 275: 18615-18618. [Abstract] [Full Text] [PDF]  

Margit Widmann and Philipp Christen
Comparison of Folding Rates of Homologous Prokaryotic and Eukaryotic Proteins
J. Biol. Chem. 2000 275: 18619-18622. [Abstract] [Full Text] [PDF]  


DNA: Replication Repair and Recombination:

Li Liu, Jin-yao Mo, Esther M. Rodriguez-Belmonte, and Marietta Y. W. T. Lee
Identification of a Fourth Subunit of Mammalian DNA Polymerase delta
J. Biol. Chem. 2000 275: 18739-18744. [Abstract] [Full Text] [PDF]  

Joon-Kyu Lee and Jerard Hurwitz
Isolation and Characterization of Various Complexes of the Minichromosome Maintenance Proteins of Schizosaccharomyces pombe
J. Biol. Chem. 2000 275: 18871-18878. [Abstract] [Full Text] [PDF]  

Margarita Sandigursky and William A. Franklin
Uracil-DNA Glycosylase in the Extreme Thermophile Archaeoglobus fulgidus
J. Biol. Chem. 2000 275: 19146-19149. [Abstract] [Full Text] [PDF]  


Genes: Structure and Regulation:

Jacques Pantel, Kalotina Machinis, Marie-Laure Sobrier, Philippe Duquesnoy, Michel Goossens, and Serge Amselem
Species-specific Alternative Splice Mimicry at the Growth Hormone Receptor Locus Revealed by the Lineage of Retroelements during Primate Evolution. A NOVEL MECHANISM ACCOUNTING FOR PROTEIN DIVERSITY BETWEEN AND WITHIN SPECIES
J. Biol. Chem. 2000 275: 18664-18669. [Abstract] [Full Text] [PDF]  

Kathrin Körner and Rolf Müller
In Vivo Structure of the Cell Cycle-regulated Human cdc25C Promoter
J. Biol. Chem. 2000 275: 18676-18681. [Abstract] [Full Text] [PDF]  

Hervé Ginisty, Guillaume Serin, Laurence Ghisolfi-Nieto, Benoit Roger, Virginie Libante, François Amalric, and Philippe Bouvet
Interaction of Nucleolin with an Evolutionarily Conserved Pre-ribosomal RNA Sequence Is Required for the Assembly of the Primary Processing Complex
J. Biol. Chem. 2000 275: 18845-18850. [Abstract] [Full Text] [PDF]  

Laurie A. Boyer, Colin Logie, Edgar Bonte, Peter B. Becker, Paul A. Wade, Alan P. Wolffe, Carl Wu, Anthony N. Imbalzano, and Craig L. Peterson
Functional Delineation of Three Groups of the ATP-dependent Family of Chromatin Remodeling Enzymes
J. Biol. Chem. 2000 275: 18864-18870. [Abstract] [Full Text] [PDF]  

Srinivas Mummidi, Mike Bamshad, Seema S. Ahuja, Enrique Gonzalez, Pablo M. Feuillet, Kazi Begum, M. Cristina Galvis, Vannessa Kostecki, Anthony J. Valente, Krishna K. Murthy, Luis Haro, Matthew J. Dolan, Jonathan S. Allan, and Sunil K. Ahuja
Evolution of Human and Non-human Primate CC Chemokine Receptor 5 Gene and mRNA. POTENTIAL ROLES FOR HAPLOTYPE AND mRNA DIVERSITY, DIFFERENTIAL HAPLOTYPE-SPECIFIC TRANSCRIPTIONAL ACTIVITY, AND ALTERED TRANSCRIPTION FACTOR BINDING TO POLYMORPHIC NUCLEOTIDES IN THE PATHOGENESIS OF HIV-1 AND SIMIAN IMMUNODEFICIENCY VIRUS
J. Biol. Chem. 2000 275: 18946-18961. [Abstract] [Full Text] [PDF] Supplemental Data  

Jörg Ziegler, Irene Stenzel, Bettina Hause, Helmut Maucher, Mats Hamberg, Rudi Grimm, Martin Ganal, and Claus Wasternack
Molecular Cloning of Allene Oxide Cyclase. THE ENZYME ESTABLISHING THE STEREOCHEMISTRY OF OCTADECANOIDS AND JASMONATES
J. Biol. Chem. 2000 275: 19132-19138. [Abstract] [Full Text] [PDF]  

James M. Dubbs, Terry H. Bird, Carl E. Bauer, and F. Robert Tabita
Interaction of CbbR and RegA* Transcription Regulators with the Rhodobacter sphaeroides cbbI Promoter-Operator Region
J. Biol. Chem. 2000 275: 19224-19230. [Abstract] [Full Text] [PDF]  

Diego Albani, Luisa Mariconti, Stefano Ricagno, Letizia Pitto, Cristina Moroni, Kristian Helin, and Rino Cella
DcE2F, a Functional Plant E2F-like Transcriptional Activator from Daucus carota
J. Biol. Chem. 2000 275: 19258-19267. [Abstract] [Full Text] [PDF]  

Christian Touriol, Myriam Roussigne, Marie-Claire Gensac, Hervé Prats, and Anne-Catherine Prats
Alternative Translation Initiation of Human Fibroblast Growth Factor 2 mRNA Controlled by Its 3'-Untranslated Region Involves a Poly(A) Switch and a Translational Enhancer
J. Biol. Chem. 2000 275: 19361-19367. [Abstract] [Full Text] [PDF]  

Elliott S. Klein, Jenny W. Wang, Berket Khalifa, Stacey A. Gavigan, and Roshantha A. S. Chandraratna
Recruitment of Nuclear Receptor Corepressor and Coactivator to the Retinoic Acid Receptor by Retinoid Ligands. INFLUENCE OF DNA-HETERODIMER INTERACTIONS
J. Biol. Chem. 2000 275: 19401-19408. [Abstract] [Full Text] [PDF]  

Wenwen Chien and Lin Pei
A Novel Binding Factor Facilitates Nuclear Translocation and Transcriptional Activation Function of the Pituitary Tumor-transforming Gene Product
J. Biol. Chem. 2000 275: 19422-19427. [Abstract] [Full Text] [PDF]  


RNA: Structure Metabolism and Catalysis:

Gaël Cristofari, Damien Ficheux, and Jean-Luc Darlix
The Gag-like Protein of the Yeast Ty1 Retrotransposon Contains a Nucleic Acid Chaperone Domain Analogous to Retroviral Nucleocapsid Proteins
J. Biol. Chem. 2000 275: 19210-19217. [Abstract] [Full Text] [PDF]  

Yukiko Ueda and Gautam Chaudhuri
Differential Expression of B1-containing Transcripts in Leishmania-exposed Macrophages
J. Biol. Chem. 2000 275: 19428-19432. [Abstract] [Full Text] [PDF]  


Protein Synthesis Post-Translation Modification and Degradation:

Emmanuel G. Reynaud, Marie Pierre Leibovitch, Lionel A. J. Tintignac, Karine Pelpel, Martine Guillier, and Serge A. Leibovitch
Stabilization of MyoD by Direct Binding to p57Kip2
J. Biol. Chem. 2000 275: 18767-18776. [Abstract] [Full Text] [PDF]  

Fausto Ulloa, Clara Francí, and Francisco X. Real
GalNAc-alpha -O-benzyl Inhibits Sialylation of de Novo Synthesized Apical but Not Basolateral Sialoglycoproteins and Blocks Lysosomal Enzyme Processing in a Post-trans-Golgi Network Compartment
J. Biol. Chem. 2000 275: 18785-18793. [Abstract] [Full Text] [PDF]  

Kefeng Qin, Dun-Sheng Yang, Ying Yang, M. Azhar Chishti, Ling-Jie Meng, Hans A. Kretzschmar, Christopher M. Yip, Paul E. Fraser, and David Westaway
Copper(II)-induced Conformational Changes and Protease Resistance in Recombinant and Cellular PrP. EFFECT OF PROTEIN AGE AND DEAMIDATION
J. Biol. Chem. 2000 275: 19121-19131. [Abstract] [Full Text] [PDF]  

Celia Quevedo, Alberto Alcázar, and Matilde Salinas
Two Different Signal Transduction Pathways Are Implicated in the Regulation of Initiation Factor 2B Activity in Insulin-like Growth Factor-1-stimulated Neuronal Cells
J. Biol. Chem. 2000 275: 19192-19197. [Abstract] [Full Text] [PDF]  

Anne Chomyn, José Antonio Enriquez, Vicente Micol, Patricio Fernandez-Silva, and Giuseppe Attardi
The Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Stroke-like Episode Syndrome-associated Human Mitochondrial tRNALeu(UUR) Mutation Causes Aminoacylation Deficiency and Concomitant Reduced Association of mRNA with Ribosomes
J. Biol. Chem. 2000 275: 19198-19209. [Abstract] [Full Text] [PDF]  


Genomics Proteomics and Bioinformatics:

Yanggu Shi, Stephen J. Ullrich, Jun Zhang, Kevin Connolly, Krzysztof J. Grzegorzewski, Melisa C. Barber, Wei Wang, Karen Wathen, Vermettya Hodge, Carrie L. Fisher, Henrik Olsen, Steve M. Ruben, Irina Knyazev, Yun Hee Cho, Viktor Kao, Kirsten A. Wilkinson, Jeffrey A. Carrell, and Reinhard Ebner
A Novel Cytokine Receptor-Ligand Pair. IDENTIFICATION, MOLECULAR CHARACTERIZATION, AND IN VIVO IMMUNOMODULATORY ACTIVITY
J. Biol. Chem. 2000 275: 19167-19176. [Abstract] [Full Text] [PDF]  


Protein Structure and Folding:

Vikram G. Panse, Pia Vogel, Wolfgang E. Trommer, and Raghavan Varadarajan
A Thermodynamic Coupling Mechanism for the Disaggregation of a Model Peptide Substrate by Chaperone SecB
J. Biol. Chem. 2000 275: 18698-18703. [Abstract] [Full Text] [PDF]  

Chenghua Liu, Robert R. Gilmont, Rainer Benndorf, and Michael J. Welsh
Identification and Characterization of a Novel Protein from Sertoli Cells, PASS1, That Associates with Mammalian Small Stress Protein hsp27
J. Biol. Chem. 2000 275: 18724-18731. [Abstract] [Full Text] [PDF]  

Stefanie Barbirz, Ursula Jakob, and Michael O. Glocker
Mass Spectrometry Unravels Disulfide Bond Formation as the Mechanism That Activates a Molecular Chaperone
J. Biol. Chem. 2000 275: 18759-18766. [Abstract] [Full Text] [PDF]  

Jun Hang, Haifeng Shi, Dongyang Li, Yinglei Liao, Dejun Lian, Yazhong Xiao, and Hong Xue
Ligand Binding and Structural Properties of Segments of GABAA Receptor alpha 1 Subunit Overexpressed in Escherichia coli
J. Biol. Chem. 2000 275: 18818-18823. [Abstract] [Full Text] [PDF]  

Karen L. Maxwell, Alan R. Davidson, Helios Murialdo, and Marvin Gold
Thermodynamic and Functional Characterization of Protein W from Bacteriophage lambda . THE THREE C-TERMINAL RESIDUES ARE CRITICAL FOR ACTIVITY
J. Biol. Chem. 2000 275: 18879-18886. [Abstract] [Full Text] [PDF]  

Umesh Desai, Richard Swanson, Susan C. Bock, Ingemar Björk, and Steven T. Olson
Role of Arginine 129 in Heparin Binding and Activation of Antithrombin
J. Biol. Chem. 2000 275: 18976-18984. [Abstract] [Full Text] [PDF]  

Gillian M. Hynes and Keith R. Willison
Individual Subunits of the Eukaryotic Cytosolic Chaperonin Mediate Interactions with Binding Sites Located on Subdomains of beta -Actin
J. Biol. Chem. 2000 275: 18985-18994. [Abstract] [Full Text] [PDF]  

Orla Cunningham, Aisling Dunne, Portia Sabido, David Lightner, and Timothy J. Mantle
Studies on the Specificity of the Tetrapyrrole Substrate for Human Biliverdin-IXalpha Reductase and Biliverdin-IXbeta Reductase. STRUCTURE-ACTIVITY RELATIONSHIPS DEFINE MODELS FOR BOTH ACTIVE SITES
J. Biol. Chem. 2000 275: 19009-19017. [Abstract] [Full Text] [PDF]  

Norelle L. Daly and David J. Craik
Acyclic Permutants of Naturally Occurring Cyclic Proteins. CHARACTERIZATION OF CYSTINE KNOT AND beta -SHEET FORMATION IN THE MACROCYCLIC POLYPEPTIDE KALATA B1
J. Biol. Chem. 2000 275: 19068-19075. [Abstract] [Full Text] [PDF]  

Miguel A. Cruz, Thomas G. Diacovo, Jonas Emsley, Robert Liddington, and Robert I. Handin
Mapping the Glycoprotein Ib-binding Site in the von Willebrand Factor A1 Domain
J. Biol. Chem. 2000 275: 19098-19105. [Abstract] [Full Text] [PDF]  

Ding-Kwo Chang, Shu-Fang Cheng, Vishwa Deo Trivedi, and Shyh-Haur Yang
The Amino-terminal Region of the Fusion Peptide of Influenza Virus Hemagglutinin HA2 Inserts into Sodium Dodecyl Sulfate Micelle with Residues 16-18 at the Aqueous Boundary at Acidic pH. OLIGOMERIZATION AND THE CONFORMATIONAL FLEXIBILITY
J. Biol. Chem. 2000 275: 19150-19158. [Abstract] [Full Text] [PDF] Supplemental Data  

Verena Girrbach, Thomas Zeller, Meike Priesmeier, and Sabine Strahl-Bolsinger
Structure-Function Analysis of the Dolichyl Phosphate-Mannose: Protein O-Mannosyltransferase ScPmt1p
J. Biol. Chem. 2000 275: 19288-19296. [Abstract] [Full Text] [PDF]  

Elzbieta Szczesna-Skorupa and Byron Kemper
Endoplasmic Reticulum Retention Determinants in the Transmembrane and Linker Domains of Cytochrome P450 2C1
J. Biol. Chem. 2000 275: 19409-19415. [Abstract] [Full Text] [PDF]  


Enzyme Catalysis and Regulation:

Stefano Marini, Giovanni Francesco Fasciglione, Giampiero de Sanctis, Silvana D'Alessio, Vincenzo Politi, and Massimo Coletta
Cleavage of Bovine Collagen I by Neutrophil Collagenase MMP-8. EFFECT OF pH ON THE CATALYTIC PROPERTIES AS COMPARED TO SYNTHETIC SUBSTRATES
J. Biol. Chem. 2000 275: 18657-18663. [Abstract] [Full Text] [PDF]  

Michael W. LaCount, Erli Zhang, Yung Pin Chen, Kaiping Han, Margaret M. Whitton, David E. Lincoln, Sarah A. Woodin, and Lukasz Lebioda
The Crystal Structure and Amino Acid Sequence of Dehaloperoxidase from Amphitrite ornata Indicate Common Ancestry with Globins
J. Biol. Chem. 2000 275: 18712-18716. [Abstract] [Full Text] [PDF]  

Jesus G. Valenzuela, Rosane Charlab, Thomas N. Mather, and José M. C. Ribeiro
Purification, Cloning, and Expression of a Novel Salivary Anticomplement Protein from the Tick, Ixodes scapularis
J. Biol. Chem. 2000 275: 18717-18723. [Abstract] [Full Text] [PDF]  

Chunghee Lee, Seung Ryul Kim, Joon-Ki Chung, Michael A. Frohman, Manfred W. Kilimann, and Sue Goo Rhee
Inhibition of Phospholipase D by Amphiphysins
J. Biol. Chem. 2000 275: 18751-18758. [Abstract] [Full Text] [PDF]  

Patrick J. Hillas, Federico Soto del Alba, Julen Oyarzabal, Angela Wilks, and Paul R. Ortiz de Montellano
The AhpC and AhpD Antioxidant Defense System of Mycobacterium tuberculosis
J. Biol. Chem. 2000 275: 18801-18809. [Abstract] [Full Text] [PDF]  

Chao Su, Margareta Sahlin, and Ernst H. Oliw
Kinetics of Manganese Lipoxygenase with a Catalytic Mononuclear Redox Center
J. Biol. Chem. 2000 275: 18830-18835. [Abstract] [Full Text] [PDF]  

Irmgard Ziegler, Thomas McDonaldo, Christian Hesslinger, Isabelle Pelletier, and Peter Boyle
Development of the Pteridine Pathway in the Zebrafish, Danio rerio
J. Biol. Chem. 2000 275: 18926-18932. [Abstract] [Full Text] [PDF]  

Jun Ishijima, Tadashi Nakai, Shin-ichi Kawaguchi, Ken Hirotsu, and Seiki Kuramitsu
Free Energy Requirement for Domain Movement of an Enzyme
J. Biol. Chem. 2000 275: 18939-18945. [Abstract] [Full Text] [PDF]  

Jennifer A. Cobb and Daniel M. Roberts
Structural Requirements for N-Trimethylation of Lysine 115 of Calmodulin
J. Biol. Chem. 2000 275: 18969-18975. [Abstract] [Full Text] [PDF]  

Akiko Hijikata-Okunomiya, Yoshikuni Tamao, Ryoji Kikumoto, and Shosuke Okamoto
Selective Inhibition of Trypsin by (2R,4R)-4-Phenyl-1-[Nalpha -(7- methoxy-2-naphthalenesulfonyl)-L-arginyl]-2-piperidinecarboxylic Acid
J. Biol. Chem. 2000 275: 18995-18999. [Abstract] [Full Text] [PDF]  

Annette Biederbick, Christian Kosan, Jürgen Kunz, and Hans-Peter Elsässer
First Apyrase Splice Variants Have Different Enzymatic Properties
J. Biol. Chem. 2000 275: 19018-19024. [Abstract] [Full Text] [PDF]  

Carole Creuzenet, Myriam Belanger, Warren W. Wakarchuk, and Joseph S. Lam
Expression, Purification, and Biochemical Characterization of WbpP, a New UDP-GlcNAc C4 Epimerase from Pseudomonas aeruginosa Serotype O6
J. Biol. Chem. 2000 275: 19060-19067. [Abstract] [Full Text] [PDF]  

Matthew P. Patricelli and Benjamin F. Cravatt
Clarifying the Catalytic Roles of Conserved Residues in the Amidase Signature Family
J. Biol. Chem. 2000 275: 19177-19184. [Abstract] [Full Text] [PDF]  

E. Lucile White, Larry J. Ross, Richard L. Davis, Sabrina Zywno-van Ginkel, Geetha Vasanthakumar, and David W. Borhani
The Two Toxoplasma gondii Hypoxanthine-Guanine Phosphoribosyltransferase Isozymes Form Heterotetramers
J. Biol. Chem. 2000 275: 19218-19223. [Abstract] [Full Text] [PDF]  

Dora Abena Armah and Kojo Mensa-Wilmot
Tetramerization of Glycosylphosphatidylinositol-specific Phospholipase C from Trypanosoma brucei
J. Biol. Chem. 2000 275: 19334-19342. [Abstract] [Full Text] [PDF]  


Metabolism and Bioenergetics:

Jingxiang Bai and Arthur I. Cederbaum
Overexpression of Catalase in the Mitochondrial or Cytosolic Compartment Increases Sensitivity of HepG2 Cells to Tumor Necrosis Factor-alpha -induced Apoptosis
J. Biol. Chem. 2000 275: 19241-19249. [Abstract] [Full Text] [PDF]  

Emia W. Oppenheim, Ilya M. Nasrallah, Maria G. Mastri, and Patrick J. Stover
Mimosine Is a Cell-specific Antagonist of Folate Metabolism
J. Biol. Chem. 2000 275: 19268-19274. [Abstract] [Full Text] [PDF]  


Glycobiology and Extracellular Matrices:

Oren Dwir, Geoffrey. S. Kansas, and Ronen Alon
An Activated L-selectin Mutant with Conserved Equilibrium Binding Properties but Enhanced Ligand Recognition under Shear Flow
J. Biol. Chem. 2000 275: 18682-18691. [Abstract] [Full Text] [PDF]  

Lennart S. Forsberg, U. Ramadas Bhat, and Russell W. Carlson
Structural Characterization of the O-antigenic Polysaccharide of the Lipopolysaccharide from Rhizobium etli Strain CE3. A UNIQUE O-ACETYLATED GLYCAN OF DISCRETE SIZE, CONTAINING 3-O-METHYL-6-DEOXY-L-TALOSE AND 2,3,4-TRI-O-METHYL-L-FUCOSE
J. Biol. Chem. 2000 275: 18851-18863. [Abstract] [Full Text] [PDF]  

Olga Klezovitch, Marilena Formato, Gian M. Cherchi, Karl H. Weisgraber, and Angelo M. Scanu
Structural Determinants in the C-terminal Domain of Apolipoprotein E Mediating Binding to the Protein Core of Human Aortic Biglycan
J. Biol. Chem. 2000 275: 18913-18918. [Abstract] [Full Text] [PDF]  

Lynn M. Thomson, Steven Bates, Soh Yamazaki, Mikio Arisawa, Yuko Aoki, and Neil A. R. Gow
Functional Characterization of the Candida albicans MNT1 Mannosyltransferase Expressed Heterologously in Pichia pastoris
J. Biol. Chem. 2000 275: 18933-18938. [Abstract] [Full Text] [PDF]  

Haruko Ogawa, Hisako Muramatsu, Takaaki Kobayashi, Kunio Morozumi, Itsuo Yokoyama, Nobuyuki Kurosawa, Akimasa Nakao, and Takashi Muramatsu
Molecular Cloning of Endo-beta -galactosidase C and Its Application in Removing alpha -Galactosyl Xenoantigen from Blood Vessels in the Pig Kidney
J. Biol. Chem. 2000 275: 19368-19374. [Abstract] [Full Text] [PDF]  


Lipids and Lipoproteins:

David L. Williams, Margarita de la Llera-Moya, Stephen T. Thuahnai, Sissel Lund-Katz, Margery A. Connelly, Salman Azhar, G. M. Anantharamaiah, and Michael C. Phillips
Binding and Cross-linking Studies Show That Scavenger Receptor BI Interacts with Multiple Sites in Apolipoprotein A-I and Identify the Class A Amphipathic alpha -Helix as a Recognition Motif
J. Biol. Chem. 2000 275: 18897-18904. [Abstract] [Full Text] [PDF]  


Membrane Transport Structure Function and Biogenesis:

Philippe Champeil, Thierry Menguy, Christophe Tribet, Jean-Luc Popot, and Marc le Maire
Interaction of Amphipols with Sarcoplasmic Reticulum Ca2+-ATPase
J. Biol. Chem. 2000 275: 18623-18637. [Abstract] [Full Text] [PDF]  

James C. Byrd and Richard G. MacDonald
Mechanisms for High Affinity Mannose 6-Phosphate Ligand Binding to the Insulin-like Growth Factor II/Mannose 6-Phosphate Receptor. NEGATIVE COOPERATIVITY AND RECEPTOR OLIGOMERIZATION
J. Biol. Chem. 2000 275: 18638-18646. [Abstract] [Full Text] [PDF]  

James C. Byrd, Jung H. Y. Park, Beverly S. Schaffer, Farideh Garmroudi, and Richard G. MacDonald
Dimerization of the Insulin-like Growth Factor II/Mannose 6-Phosphate Receptor
J. Biol. Chem. 2000 275: 18647-18656. [Abstract] [Full Text] [PDF]  

Tomomi Kimura-Someya, Shinobu Iwaki, Satoko Konishi, Norihisa Tamura, Yoshiyuki Kubo, and Akihito Yamaguchi
Cysteine-scanning Mutagenesis around Transmembrane Segments 1 and 11 and Their Flanking Loop Regions of Tn10-encoded Metal-Tetracycline/H+ Antiporter
J. Biol. Chem. 2000 275: 18692-18697. [Abstract] [Full Text] [PDF]  

Holger Barth, Dagmar Blöcker, Joachim Behlke, Wilma Bergsma-Schutter, Alain Brisson, Roland Benz, and Klaus Aktories
Cellular Uptake of Clostridium botulinum C2 Toxin Requires Oligomerization and Acidification
J. Biol. Chem. 2000 275: 18704-18711. [Abstract] [Full Text] [PDF]  

Maria Esther Martín, Josefina Hidalgo, Jose Luis Rosa, Pascal Crottet, and Angel Velasco
Effect of Protein Kinase A Activity on the Association of ADP-ribosylation Factor 1 to Golgi Membranes
J. Biol. Chem. 2000 275: 19050-19059. [Abstract] [Full Text] [PDF]  

Yi-Kang Hu and Jack H. Kaplan
Site-directed Chemical Labeling of Extracellular Loops in a Membrane Protein. THE TOPOLOGY OF THE Na,K-ATPase alpha -SUBUNIT
J. Biol. Chem. 2000 275: 19185-19191. [Abstract] [Full Text] [PDF]  


Mechanisms Of Signal Transduction:

John H. Connor, Deborah Frederick, Hsien-bin Huang, Jie Yang, Nicholas R. Helps, Patricia T. W. Cohen, Angus C. Nairn, Anna DePaoli-Roach, Kelly Tatchell, and Shirish Shenolikar
Cellular Mechanisms Regulating Protein Phosphatase-1. A KEY FUNCTIONAL INTERACTION BETWEEN INHIBITOR-2 AND THE TYPE 1 PROTEIN PHOSPHATASE CATALYTIC SUBUNIT
J. Biol. Chem. 2000 275: 18670-18675. [Abstract] [Full Text] [PDF]  

Nabil Djouder, Ulrike Prepens, Klaus Aktories, and Adolfo Cavalié
Inhibition of Calcium Release-activated Calcium Current by Rac/Cdc42-inactivating Clostridial Cytotoxins in RBL Cells
J. Biol. Chem. 2000 275: 18732-18738. [Abstract] [Full Text] [PDF]  

Hae-Young Sohn, Matthias Keller, Torsten Gloe, Henning Morawietz, Uwe Rueckschloss, and Ulrich Pohl
The Small G-protein Rac Mediates Depolarization-induced Superoxide Formation in Human Endothelial Cells
J. Biol. Chem. 2000 275: 18745-18750. [Abstract] [Full Text] [PDF]  

Susanne G. Straub, Bruce Kornreich, Robert E. Oswald, Edward F. Nemeth, and Geoffrey W. G. Sharp
The Calcimimetic R-467 Potentiates Insulin Secretion in Pancreatic beta  Cells by Activation of a Nonspecific Cation Channel
J. Biol. Chem. 2000 275: 18777-18784. [Abstract] [Full Text] [PDF]  

Olivier Coqueret and Hugues Gascan
Functional Interaction of STAT3 Transcription Factor with the Cell Cycle Inhibitor p21WAF1/CIP1/SDI1
J. Biol. Chem. 2000 275: 18794-18800. [Abstract] [Full Text] [PDF]  

Lara Terstegen, Petros Gatsios, Johannes G. Bode, Fred Schaper, Peter C. Heinrich, and Lutz Graeve
The Inhibition of Interleukin-6-dependent STAT Activation by Mitogen-activated Protein Kinases Depends on Tyrosine 759 in the Cytoplasmic Tail of Glycoprotein 130
J. Biol. Chem. 2000 275: 18810-18817. [Abstract] [Full Text] [PDF]  

Jan Jakubík, Esam E. El-Fakahany, and Stanislav Tucek
Evidence for a Tandem Two-site Model of Ligand Binding to Muscarinic Acetylcholine Receptors
J. Biol. Chem. 2000 275: 18836-18844. [Abstract] [Full Text] [PDF]  

Songwei Wu, Timothy M. Moore, George H. Brough, Sherry R. Whitt, Michael Chinkers, Ming Li, and Troy Stevens
Cyclic Nucleotide-gated Channels Mediate Membrane Depolarization following Activation of Store-operated Calcium Entry in Endothelial Cells
J. Biol. Chem. 2000 275: 18887-18896. [Abstract] [Full Text] [PDF]  

Serguei G. Popov, U. Murali Krishna, J. R. Falck, and Thomas M. Wilkie
Ca2+/Calmodulin Reverses Phosphatidylinositol 3,4,5-Trisphosphate-dependent Inhibition of Regulators of G Protein-signaling GTPase-activating Protein Activity
J. Biol. Chem. 2000 275: 18962-18968. [Abstract] [Full Text] [PDF]  

Meina Liang, Cornell Mallari, Mary Rosser, Howard P. Ng, Karen May, Sean Monahan, John G. Bauman, Imadul Islam, Ameen Ghannam, Brad Buckman, Ken Shaw, Guo-Ping Wei, Wei Xu, Zuchun Zhao, Elena Ho, Jun Shen, Huynh Oanh, Babu Subramanyam, Ron Vergona, Dennis Taub, Laura Dunning, Susan Harvey, R. Michael Snider, Joseph Hesselgesser, Michael M. Morrissey, H. Daniel Perez, and Richard Horuk
Identification and Characterization of a Potent, Selective, and Orally Active Antagonist of the CC Chemokine Receptor-1
J. Biol. Chem. 2000 275: 19000-19008. [Abstract] [Full Text] [PDF]  

Fubao Lin, Hsien-yu Wang, and Craig C. Malbon
Gravin-mediated Formation of Signaling Complexes in beta 2-Adrenergic Receptor Desensitization and Resensitization
J. Biol. Chem. 2000 275: 19025-19034. [Abstract] [Full Text] [PDF]  

Ya Fang Liu, Donna Dorow, and John Marshall
Activation of MLK2-mediated Signaling Cascades by Polyglutamine-expanded Huntingtin
J. Biol. Chem. 2000 275: 19035-19040. [Abstract] [Full Text] [PDF]  

Ulrika Lind, Paulette Greenidge, Mikael Gillner, Konrad F. Koehler, Anthony Wright, and Jan Carlstedt-Duke
Functional Probing of the Human Glucocorticoid Receptor Steroid-interacting Surface by Site-directed Mutagenesis. Gln-642 PLAYS AN IMPORTANT ROLE IN STEROID RECOGNITION AND BINDING
J. Biol. Chem. 2000 275: 19041-19049. [Abstract] [Full Text] [PDF]  

Jiuhong Yu, Thomas F. Deuel, and Hyeong-Reh Choi Kim
Platelet-derived Growth Factor (PDGF) Receptor-alpha Activates c-Jun NH2-terminal Kinase-1 and Antagonizes PDGF Receptor-beta -induced Phenotypic Transformation
J. Biol. Chem. 2000 275: 19076-19082. [Abstract] [Full Text] [PDF]  

Hyewon Phee, Anand Jacob, and K. Mark Coggeshall
Enzymatic Activity of the Src Homology 2 Domain-containing Inositol Phosphatase Is Regulated by a Plasma Membrane Location
J. Biol. Chem. 2000 275: 19090-19097. [Abstract] [Full Text] [PDF]  

Baoan Ji, Alan S. Kopin, and Craig D. Logsdon
Species Differences between Rat and Mouse CCKA Receptors Determine the Divergent Acinar Cell Response to the Cholecystokinin Analog JMV-180
J. Biol. Chem. 2000 275: 19115-19120. [Abstract] [Full Text] [PDF]  

Petra Maschberger, Markus Bauer, Jutta Baumann-Siemons, Konrad J. Zangl, Emil V. Negrescu, Armin J. Reininger, and Wolfgang Siess
Mildly Oxidized Low Density Lipoprotein Rapidly Stimulates via Activation of the Lysophosphatidic Acid Receptor Src Family and Syk Tyrosine Kinases and Ca2+ Influx in Human Platelets
J. Biol. Chem. 2000 275: 19159-19166. [Abstract] [Full Text] [PDF]  

Joan M. Taylor, Joshua D. Rovin, and J. Thomas Parsons
A Role for Focal Adhesion Kinase in Phenylephrine-induced Hypertrophy of Rat Ventricular Cardiomyocytes
J. Biol. Chem. 2000 275: 19250-19257. [Abstract] [Full Text] [PDF]  

Baihua Chen, Scott C. Borinstein, Jennifer Gillis, Virginia W. Sykes, and Oliver Bogler
The Glioma-associated Protein SETA Interacts with AIP1/Alix and ALG-2 and Modulates Apoptosis in Astrocytes
J. Biol. Chem. 2000 275: 19275-19281. [Abstract] [Full Text] [PDF]  

Virginie Lafont, Janny Liautard, Antoine Gross, Jean Pierre Liautard, and Jean Favero
Tumor Necrosis Factor-alpha Production Is Differently Regulated in gamma delta and alpha beta Human T Lymphocytes
J. Biol. Chem. 2000 275: 19282-19287. [Abstract] [Full Text] [PDF]  

Daniela Califano, Claudia Rizzo, Amelia D'Alessio, G. Luca Colucci-D'Amato, Gaetano Calì, Paola Cannada Bartoli, Giovanni Santelli, Giancarlo Vecchio, and Vittorio de Franciscis
Signaling through Ras Is Essential for ret Oncogene-induced Cell Differentiation in PC12 Cells
J. Biol. Chem. 2000 275: 19297-19305. [Abstract] [Full Text] [PDF]  

G. Luca Colucci-D'Amato, Amelia D'Alessio, Daniela Califano, Gaetano Calì, Claudia Rizzo, Lucio Nitsch, Giovanni Santelli, and Vittorio de Franciscis
Abrogation of Nerve Growth Factor-induced Terminal Differentiation by ret Oncogene Involves Perturbation of Nuclear Translocation of ERK
J. Biol. Chem. 2000 275: 19306-19314. [Abstract] [Full Text] [PDF]  

Janice C. Wolfman and Alan Wolfman
Endogenous c-N-Ras Provides a Steady-state Anti-apoptotic Signal
J. Biol. Chem. 2000 275: 19315-19323. [Abstract] [Full Text] [PDF]  

Hidenori Shiraha, Kiran Gupta, Kathryn Drabik, and Alan Wells
Aging Fibroblasts Present Reduced Epidermal Growth Factor (EGF) Responsiveness Due to Preferential Loss of EGF Receptors
J. Biol. Chem. 2000 275: 19343-19351. [Abstract] [Full Text] [PDF]  

Symeon Siniossoglou, Ed C. Hurt, and Hugh R. B. Pelham
Psr1p/Psr2p, Two Plasma Membrane Phosphatases with an Essential DXDX(T/V) Motif Required for Sodium Stress Response in Yeast
J. Biol. Chem. 2000 275: 19352-19360. [Abstract] [Full Text] [PDF]  

Diem H. D. Nguyen, Donna J. Webb, Andrew D. Catling, Qian Song, Anita Dhakephalkar, Michael J. Weber, Kodimangalam S. Ravichandran, and Steven L. Gonias
Urokinase-type Plasminogen Activator Stimulates the Ras/Extracellular Signal-regulated Kinase (ERK) Signaling Pathway and MCF-7 Cell Migration by a Mechanism That Requires Focal Adhesion Kinase, Src, and Shc. RAPID DISSOCIATION OF GRB2/SOS-SHC COMPLEX IS ASSOCIATED WITH THE TRANSIENT PHOSPHORYLATION OF ERK IN UROKINASE-TREATED CELLS
J. Biol. Chem. 2000 275: 19382-19388. [Abstract] [Full Text] [PDF]  

Toshiki Itoh, Hisamitsu Ishihara, Yoshikazu Shibasaki, Yoshitomo Oka, and Tadaomi Takenawa
Autophosphorylation of Type I Phosphatidylinositol Phosphate Kinase Regulates Its Lipid Kinase Activity
J. Biol. Chem. 2000 275: 19389-19394. [Abstract] [Full Text] [PDF]  

Catherine Communal, Wilson S. Colucci, and Krishna Singh
p38 Mitogen-activated Protein Kinase Pathway Protects Adult Rat Ventricular Myocytes against beta -Adrenergic Receptor-stimulated Apoptosis. EVIDENCE FOR Gi-DEPENDENT ACTIVATION
J. Biol. Chem. 2000 275: 19395-19400. [Abstract] [Full Text] [PDF]  

Prakash Prabhakar, Van Cheng, and Thomas Michel
A Chimeric Transmembrane Domain Directs Endothelial Nitric-oxide Synthase Palmitoylation and Targeting to Plasmalemmal Caveolae
J. Biol. Chem. 2000 275: 19416-19421. [Abstract] [Full Text] [PDF]  


Molecular Basis Of Cell and Developmental Biology:

Raymond V. Fucini, Araceli Navarrete, Catherine Vadakkan, Lynne Lacomis, Hediye Erdjument-Bromage, Paul Tempst, and Mark Stamnes
Activated ADP-ribosylation Factor Assembles Distinct Pools of Actin on Golgi Membranes
J. Biol. Chem. 2000 275: 18824-18829. [Abstract] [Full Text] [PDF]  

Pinfen Yang and Winfield S. Sale
Casein Kinase I Is Anchored on Axonemal Doublet Microtubules and Regulates Flagellar Dynein Phosphorylation and Activity
J. Biol. Chem. 2000 275: 18905-18912. [Abstract] [Full Text] [PDF]  

Christian Sohlenkamp, Karel E. E. de Rudder, Viola Röhrs, Isabel M. López-Lara, and Otto Geiger
Cloning and Characterization of the Gene for Phosphatidylcholine Synthase
J. Biol. Chem. 2000 275: 18919-18925. [Abstract] [Full Text] [PDF]  

Hiromi Hirata, Toshiyuki Ohtsuka, Yasumasa Bessho, and Ryoichiro Kageyama
Generation of Structurally and Functionally Distinct Factors from the Basic Helix-Loop-Helix Gene Hes3 by Alternative First Exons
J. Biol. Chem. 2000 275: 19083-19089. [Abstract] [Full Text] [PDF]  

Petra T. Schwartz, Beatriz Pérez-Villamil, Alicia Rivera, Rosario Moratalla, and Mario Vallejo
Pancreatic Homeodomain Transcription Factor IDX1/IPF1 Expressed in Developing Brain Regulates Somatostatin Gene Transcription in Embryonic Neural Cells
J. Biol. Chem. 2000 275: 19106-19114. [Abstract] [Full Text] [PDF]  

Diana Palmeri, Annemieke van Zante, Chiao-Chain Huang, Stefan Hemmerich, and Steven D. Rosen
Vascular Endothelial Junction-associated Molecule, a Novel Member of the Immunoglobulin Superfamily, Is Localized to Intercellular Boundaries of Endothelial Cells
J. Biol. Chem. 2000 275: 19139-19145. [Abstract] [Full Text] [PDF]  

Derrick T. Brazill, David R. Caprette, Heather A. Myler, R. Diane Hatton, Robin R. Ammann, David F. Lindsey, Debra A. Brock, and Richard H. Gomer
A Protein Containing a Serine-rich Domain with Vesicle Fusing Properties Mediates Cell Cycle-dependent Cytosolic pH Regulation
J. Biol. Chem. 2000 275: 19231-19240. [Abstract] [Full Text] [PDF]  

Richard C. Johnson, Peter Penzes, Betty A. Eipper, and Richard E. Mains
Isoforms of Kalirin, a Neuronal Dbl Family Member, Generated through Use of Different 5'- and 3'-Ends Along with an Internal Translational Initiation Site
J. Biol. Chem. 2000 275: 19324-19333. [Abstract] [Full Text] [PDF]  

Veronique A. J. Smits, Maartje A. van Peer, Marieke A. G. Essers, Rob Klompmaker, Gert Rijksen, and René H. Medema
Negative Growth Regulation of SK-N-MC Cells by bFGF Defines a Growth Factor-sensitive Point in G2
J. Biol. Chem. 2000 275: 19375-19381. [Abstract] [Full Text] [PDF]  


Additions and Corrections:

Surender Kharbanda, Satya Saxena, Kiyotsugu Yoshida, Pramod Pandey, Masao Kaneki, Qizhi Wang, Keding Cheng, Ying-Nan Chen, Angela Campbell, Thangrila Sudha, Zhi-Min Yuan, Jagat Narula, Ralph Weichselbaum, Carlo Nalin, and Donald Kufe
Translocation of SAPK/JNK to mitochondria and interaction with Bcl-xL in response to DNA damage.
J. Biol. Chem. 2000 275: 19433. [Full Text] [PDF]  

Rohini Muthuswami, Patrick A. Truman, Larry D. Mesner, and Joel W. Hockensmith
A eukaryotic SWI2/SNF2 domain, an exquisite detector of double-stranded to single-stranded DNA transition elements.
J. Biol. Chem. 2000 275: 19433. [Full Text] [PDF]  


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