Editorial:

JBC electronic submission required (Starting September 1, 2000)
J. Biol. Chem. 2000 275: 21781. [Full Text] [PDF]  

Minireviews:

John A. McDonald

Integrins Minireview Series
J. Biol. Chem. 2000 275: 21783. [Full Text] [PDF]  

Edward F. Plow, Thomas A. Haas, Li Zhang, Joseph Loftus, and Jeffrey W. Smith

Ligand Binding to Integrins
J. Biol. Chem. 2000 275: 21785-21788. [Full Text] [PDF]  

Accelerated Publications:

Toshio Watanabe, Naoya Ihara, Tomohito Itoh, Tatsuo Fujita, and Yoshikazu Sugimoto

Deletion Mutation in Drosophila ma-l Homologous, Putative Molybdopterin Cofactor Sulfurase Gene Is Associated with Bovine Xanthinuria Type II
J. Biol. Chem. 2000 275: 21789-21792. [Abstract] [Full Text] [PDF]  

Pradip K. Majumder, Pramod Pandey, Xiangao Sun, Keding Cheng, Rakesh Datta, Satya Saxena, Surender Kharbanda, and Donald Kufe

Mitochondrial Translocation of Protein Kinase C  in Phorbol Ester-induced Cytochrome c Release and Apoptosis
J. Biol. Chem. 2000 275: 21793-21796. [Abstract] [Full Text] [PDF]  

Rebecca C. Osthus, Hyunsuk Shim, Sunkyu Kim, Qing Li, Rahul Reddy, Mita Mukherjee, Yi Xu, Diane Wonsey, Linda A. Lee, and Chi V. Dang

Deregulation of Glucose Transporter 1 and Glycolytic Gene Expression by c-Myc
J. Biol. Chem. 2000 275: 21797-21800. [Abstract] [Full Text] [PDF]  

Douglas R. Keene, James D. San Antonio, Richard Mayne, David J. McQuillan, George Sarris, Samuel A. Santoro, and Renato V. Iozzo

Decorin Binds Near the C Terminus of Type I Collagen
J. Biol. Chem. 2000 275: 21801-21804. [Abstract] [Full Text] [PDF]  

Jon H. Miyake, Shui-Long Wang, and Roger A. Davis

Bile Acid Induction of Cytokine Expression by Macrophages Correlates with Repression of Hepatic Cholesterol 7-Hydroxylase
J. Biol. Chem. 2000 275: 21805-21808. [Abstract] [Full Text] [PDF]  

Melanie A. Stegman, Jefferson E. Vallance, Ganesh Elangovan, Janek Sosinski, Yan Cheng, and David J. Robbins

Identification of a Tetrameric Hedgehog Signaling Complex
J. Biol. Chem. 2000 275: 21809-21812. [Abstract] [Full Text] [PDF]  

Hieronim Jakubowski

Translational Incorporation of S-Nitrosohomocysteine into Protein
J. Biol. Chem. 2000 275: 21813-21816. [Abstract] [Full Text] [PDF]  

DNA: Replication Repair and Recombination:

Gena Tribble, Yong-Tae Ahn, Jehee Lee, Thomas Dandekar, and Makkuni Jayaram

DNA Recognition, Strand Selectivity, and Cleavage Mode during Integrase Family Site-specific Recombination
J. Biol. Chem. 2000 275: 22255-22267. [Abstract] [Full Text] [PDF]  

Jennifer Cruickshank, Kathy Shire, Alan R. Davidson, Aled M. Edwards, and Lori Frappier

Two Domains of the Epstein-Barr Virus Origin DNA-binding Protein, EBNA1, Orchestrate Sequence-specific DNA Binding
J. Biol. Chem. 2000 275: 22273-22277. [Abstract] [Full Text] [PDF]  

Philip J. Brooks, Dean S. Wise, David A. Berry, Joseph V. Kosmoski, Michael J. Smerdon, Robert L. Somers, Hugh Mackie, Alexander Y. Spoonde, Eric J. Ackerman, Katherine Coleman, Robert E. Tarone, and Jay H. Robbins

The Oxidative DNA Lesion 8,5'-(S)-Cyclo-2'-deoxyadenosine Is Repaired by the Nucleotide Excision Repair Pathway and Blocks Gene Expression in Mammalian Cells
J. Biol. Chem. 2000 275: 22355-22362. [Abstract] [Full Text] [PDF]  

Ildiko Unk, Lajos Haracska, Robert E. Johnson, Satya Prakash, and Louise Prakash

Apurinic Endonuclease Activity of Yeast Apn2 Protein
J. Biol. Chem. 2000 275: 22427-22434. [Abstract] [Full Text] [PDF]  

Kenkichi Masutomi, Shuichi Kaneko, Naoyuki Hayashi, Tatsuya Yamashita, Yukihiro Shirota, Kenichi Kobayashi, and Seishi Murakami

Telomerase Activity Reconstituted in Vitro with Purified Human Telomerase Reverse Transcriptase and Human Telomerase RNA Component
J. Biol. Chem. 2000 275: 22568-22573. [Abstract] [Full Text] [PDF]  

Genes: Structure and Regulation:

Suzanne Carreira, Baoguo Liu, and Colin R. Goding

The Gene Encoding the T-box Factor Tbx2 Is a Target for the Microphthalmia-associated Transcription Factor in Melanocytes
J. Biol. Chem. 2000 275: 21920-21927. [Abstract] [Full Text] [PDF]  

Maxim V. Sukhodolets and Ding Jun Jin

Interaction between RNA Polymerase and RapA, a Bacterial Homolog of the SWI/SNF Protein Family
J. Biol. Chem. 2000 275: 22090-22097. [Abstract] [Full Text] [PDF]  

Vincent J. Lannoy, Annie Rodolosse, Christophe E. Pierreux, Guy G. Rousseau, and Frédéric P. Lemaigre

Transcriptional Stimulation by Hepatocyte Nuclear Factor-6. TARGET-SPECIFIC RECRUITMENT OF EITHER CREB-BINDING PROTEIN (CBP) or p300/CBP-ASSOCIATED FACTOR (p/CAF)
J. Biol. Chem. 2000 275: 22098-22103. [Abstract] [Full Text] [PDF]  

Matthew Chaney, Melinda Pitt, and Martin Buck

Sequences within the DNA Cross-linking Patch of ⁵⁴ Involved in Promoter Recognition,  Isomerization, and Open Complex Formation
J. Biol. Chem. 2000 275: 22104-22113. [Abstract] [Full Text] [PDF]  

Colin D. Bingle, Ruth W. Craig, Brenka M. Swales, Vanessa Singleton, Ping Zhou, and Moira K. B. Whyte

Exon Skipping in Mcl-1 Results in a Bcl-2 Homology Domain 3 Only Gene Product That Promotes Cell Death
J. Biol. Chem. 2000 275: 22136-22146. [Abstract] [Full Text] [PDF]  

Chun Ren Lim, Yukio Kimata, Hidezumi Ohdate, Tetsuro Kokubo, Noriko Kikuchi, Tsuneyoshi Horigome, and Kenji Kohno

The Saccharomyces cerevisiae RuvB-like Protein, Tih2p, Is Required for Cell Cycle Progression and RNA Polymerase II-directed Transcription
J. Biol. Chem. 2000 275: 22409-22417. [Abstract] [Full Text] [PDF]  

Patricia Mora-Garcia and Kathleen M. Sakamoto

Granulocyte Colony-stimulating Factor Induces egr-1 Up-regulation through Interaction of Serum Response Element-binding Proteins
J. Biol. Chem. 2000 275: 22418-22426. [Abstract] [Full Text] [PDF]  

Tetsuya Mizutani, Kazuya Yamada, Takashi Minegishi, and Kaoru Miyamoto

Transcriptional Regulation of Rat Scavenger Receptor Class B Type I Gene
J. Biol. Chem. 2000 275: 22512-22519. [Abstract] [Full Text] [PDF]  

Protein Synthesis Post-Translation Modification and Degradation:

Eric Winstall, Martin Sadowski, Uwe Kühn, Elmar Wahle, and Alan B. Sachs

The Saccharomyces cerevisiae RNA-binding Protein Rbp29 Functions in Cytoplasmic mRNA Metabolism
J. Biol. Chem. 2000 275: 21817-21826. [Abstract] [Full Text] [PDF]  

Lia Supino-Rosin, Akihiko Yoshimura, Yossef Yarden, Zvulun Elazar, and Drorit Neumann

Intracellular Retention and Degradation of the Epidermal Growth Factor Receptor, Two Distinct Processes Mediated by Benzoquinone Ansamycins
J. Biol. Chem. 2000 275: 21850-21855. [Abstract] [Full Text] [PDF]  

Frederick S. Buckner, Kohei Yokoyama, Lisa Nguyen, Anita Grewal, Hediye Erdjument-Bromage, Paul Tempst, Corey L. Strickland, Li Xiao, Wesley C. Van Voorhis, and Michael H. Gelb

Cloning, Heterologous Expression, and Distinct Substrate Specificity of Protein Farnesyltransferase from Trypanosoma brucei
J. Biol. Chem. 2000 275: 21870-21876. [Abstract] [Full Text] [PDF]  

Julie Bastien, Sylvie Adam-Stitah, Thilo Riedl, Jean-Marc Egly, Pierre Chambon, and Cécile Rochette-Egly

TFIIH Interacts with the Retinoic Acid Receptor  and Phosphorylates Its AF-1-activating Domain through cdk7
J. Biol. Chem. 2000 275: 21896-21904. [Abstract] [Full Text] [PDF]  

Hiroshi Hosoda, Masayasu Kojima, Hisayuki Matsuo, and Kenji Kangawa

Purification and Characterization of Rat des-Gln¹⁴-Ghrelin, a Second Endogenous Ligand for the Growth Hormone Secretagogue Receptor
J. Biol. Chem. 2000 275: 21995-22000. [Abstract] [Full Text] [PDF]  

Heide L. Ford, Esther Landesman-Bollag, Caroline S. Dacwag, P. Todd Stukenberg, Arthur B. Pardee, and David C. Seldin

Cell Cycle-regulated Phosphorylation of the Human SIX1 Homeodomain Protein
J. Biol. Chem. 2000 275: 22245-22254. [Abstract] [Full Text] [PDF]  

Genomics Proteomics and Bioinformatics:

Wei Wang, Hortensia Soto, Elizabeth R. Oldham, Matthew E. Buchanan, Bernhard Homey, Daniel Catron, Nancy Jenkins, Neal G. Copeland, Debra J. Gilbert, Nhung Nguyen, John Abrams, David Kershenovich, Kathleen Smith, Terri McClanahan, Alain P. Vicari, and Albert Zlotnik

Identification of a Novel Chemokine (CCL28), which Binds CCR10 (GPR2)
J. Biol. Chem. 2000 275: 22313-22323. [Abstract] [Full Text] [PDF]  

Protein Structure and Folding:

Padmaja Yalamanchili, Chafen Lu, Claus Oxvig, and Timothy A. Springer

Folding and Function of I Domain-deleted Mac-1 and Lymphocyte Function-associated Antigen-1
J. Biol. Chem. 2000 275: 21877-21882. [Abstract] [Full Text] [PDF]  

L. V. Siva Kumar and Ch. Mohan Rao

Domain Swapping in Human A and B Crystallins Affects Oligomerization and Enhances Chaperone-like Activity
J. Biol. Chem. 2000 275: 22009-22013. [Abstract] [Full Text] [PDF]  

Andy Pascal, Ulrich Wacker, Klaus-Dieter Irrgang, Peter Horton, Gernot Renger, and Bruno Robert

Pigment Binding Site Properties of Two Photosystem II Antenna Proteins. A RESONANCE RAMAN INVESTIGATION
J. Biol. Chem. 2000 275: 22031-22036. [Abstract] [Full Text] [PDF]  

Qun Zang, Chafen Lu, Chichi Huang, Junichi Takagi, and Timothy A. Springer

The Top of the Inserted-like Domain of the Integrin Lymphocyte Function-associated Antigen-1  Subunit Contacts the  Subunit -Propeller Domain near -Sheet 3
J. Biol. Chem. 2000 275: 22202-22212. [Abstract] [Full Text] [PDF]  

Joshua A. Maurer, Donald E. Elmore, Henry A. Lester, and Dennis A. Dougherty

Comparing and Contrasting Escherichia coli and Mycobacterium tuberculosis Mechanosensitive Channels (MscL). NEW GAIN OF FUNCTION MUTATIONS IN THE LOOP REGION
J. Biol. Chem. 2000 275: 22238-22244. [Abstract] [Full Text] [PDF]  

Jiu-Li Song, R. Max Wynn, and David T. Chuang

Interactions of GroEL/GroES with a Heterodimeric Intermediate during ₂₂ Assembly of Mitochondrial Branched-chain -Ketoacid Dehydrogenase. cis CAPPING OF THE NATIVE-LIKE 86-kDa INTERMEDIATE BY GroES
J. Biol. Chem. 2000 275: 22305-22312. [Abstract] [Full Text] [PDF]  

Aileen E. Boyd, Alan B. Marnett, Lilly Wong, and Palmer Taylor

Probing the Active Center Gorge of Acetylcholinesterase by Fluorophores Linked to Substituted Cysteines
J. Biol. Chem. 2000 275: 22401-22408. [Abstract] [Full Text] [PDF]  

Armin Spura, Ryan U. Riel, Neal D. Freedman, Shantanu Agrawal, Christopher Seto, and Edward Hawrot

Biotinylation of Substituted Cysteines in the Nicotinic Acetylcholine Receptor Reveals Distinct Binding Modes for -Bungarotoxin and Erabutoxin a
J. Biol. Chem. 2000 275: 22452-22460. [Abstract] [Full Text] [PDF]  

Vicci L. Korman, Victoria Hatch, Kavara Y. Dixon, Roger Craig, William Lehman, and Larry S. Tobacman

An Actin Subdomain 2 Mutation That Impairs Thin Filament Regulation by Troponin and Tropomyosin
J. Biol. Chem. 2000 275: 22470-22478. [Abstract] [Full Text] [PDF]  

Thavamani Rajapandi, Lois E. Greene, and Evan Eisenberg

The Molecular Chaperones Hsp90 and Hsc70 Are Both Necessary and Sufficient to Activate Hormone Binding by Glucocorticoid Receptor
J. Biol. Chem. 2000 275: 22597-22604. [Abstract] [Full Text] [PDF]  

Enzyme Catalysis and Regulation:

Johan Bylund, Mats Hidestrand, Magnus Ingelman-Sundberg, and Ernst H. Oliw

Identification of CYP4F8 in Human Seminal Vesicles as a Prominent 19-Hydroxylase of Prostaglandin Endoperoxides
J. Biol. Chem. 2000 275: 21844-21849. [Abstract] [Full Text] [PDF]  

Matthias Boll, Diana Laempe, Wolfgang Eisenreich, Adelbert Bacher, Thomas Mittelberger, Jürgen Heinze, and Georg Fuchs

Nonaromatic Products from Anoxic Conversion of Benzoyl-CoA with Benzoyl-CoA Reductase and Cyclohexa-1,5-diene-1-carbonyl-CoA Hydratase
J. Biol. Chem. 2000 275: 21889-21895. [Abstract] [Full Text] [PDF]  

Linda J. Roman, R. Timothy Miller, Melissa A. de la Garza, Jung-Ja P. Kim, and Bettie Sue Siler Masters

The C Terminus of Mouse Macrophage Inducible Nitric-oxide Synthase Attenuates Electron Flow through the Flavin Domain
J. Biol. Chem. 2000 275: 21914-21919. [Abstract] [Full Text] [PDF]  

Ontario D. Lau, Aliya D. Courtney, Alex Vassilev, Lisa A. Marzilli, Robert J. Cotter, Yoshihiro Nakatani, and Philip A. Cole

p300/CBP-associated Factor Histone Acetyltransferase Processing of a Peptide Substrate. KINETIC ANALYSIS OF THE CATALYTIC MECHANISM
J. Biol. Chem. 2000 275: 21953-21959. [Abstract] [Full Text] [PDF]  

Jia Dai, Hongfa Zhu, Jianying Shi, and Gebre Woldegiorgis

Identification by Mutagenesis of Conserved Arginine and Tryptophan Residues in Rat Liver Carnitine Palmitoyltransferase I Important for Catalytic Activity
J. Biol. Chem. 2000 275: 22020-22024. [Abstract] [Full Text] [PDF]  

Kirk G. Tanner, Michael R. Langer, Youngjoo Kim, and John M. Denu

Kinetic Mechanism of the Histone Acetyltransferase GCN5 from Yeast
J. Biol. Chem. 2000 275: 22048-22055. [Abstract] [Full Text] [PDF]  

Gunter Schmidtke, Sabine Emch, Marcus Groettrup, and Hermann-Georg Holzhütter

Evidence for the Existence of a Non-catalytic Modifier Site of Peptide Hydrolysis by the 20 S Proteasome
J. Biol. Chem. 2000 275: 22056-22063. [Abstract] [Full Text] [PDF]  

Kathryn Elliott, Hugh Watkins, and Charles S. Redwood

Altered Regulatory Properties of Human Cardiac Troponin I Mutants That Cause Hypertrophic Cardiomyopathy
J. Biol. Chem. 2000 275: 22069-22074. [Abstract] [Full Text] [PDF]  

Marco Moracci, Beatrice Cobucci Ponzano, Antonio Trincone, Stefania Fusco, Mario De Rosa, John van der Oost, Christoph W. Sensen, Robert L. Charlebois, and Mose' Rossi

Identification and Molecular Characterization of the First -Xylosidase from an Archaeon
J. Biol. Chem. 2000 275: 22082-22089. [Abstract] [Full Text] [PDF]  

Sabine Wrenger, Jürgen Faust, Carmen Mrestani-Klaus, Annett Fengler, Angela Stöckel-Maschek, Susan Lorey, Thilo Kähne, Wolfgang Brandt, Klaus Neubert, Siegfried Ansorge, and Dirk Reinhold

Down-regulation of T Cell Activation following Inhibition of Dipeptidyl Peptidase IV/CD26 by the N-terminal Part of the Thromboxane A2 Receptor
J. Biol. Chem. 2000 275: 22180-22186. [Abstract] [Full Text] [PDF]  

Anna Radominska-Pandya, Guangping Chen, Piotr J. Czernik, Joanna M. Little, Victor M. Samokyszyn, Charleata A. Carter, and Graz·yna Nowak

Direct Interaction of All-trans-retinoic Acid with Protein Kinase C (PKC). IMPLICATIONS FOR PKC SIGNALING AND CANCER THERAPY
J. Biol. Chem. 2000 275: 22324-22330. [Abstract] [Full Text] [PDF]  

Metabolism and Bioenergetics:

Qing Chang, Kaihong Su, John R. Baker, Xiaoyong Yang, Andrew J. Paterson, and Jeffrey E. Kudlow

Phosphorylation of Human Glutamine:Fructose-6-phosphate Amidotransferase by cAMP-dependent Protein Kinase at Serine 205 Blocks the Enzyme Activity
J. Biol. Chem. 2000 275: 21981-21987. [Abstract] [Full Text] [PDF]  

Antti Nyyssölä, Janne Kerovuo, Pasi Kaukinen, Niklas von Weymarn, and Tapani Reinikainen

Extreme Halophiles Synthesize Betaine from Glycine by Methylation
J. Biol. Chem. 2000 275: 22196-22201. [Abstract] [Full Text] [PDF]  

Kenichi Watanabe, Hiroshi Fujii, Toshihiro Takahashi, Makoto Kodama, Yoshifusa Aizawa, Yoshimi Ohta, Teruo Ono, Go Hasegawa, Makoto Naito, Tamie Nakajima, Yuji Kamijo, Frank J. Gonzalez, and Toshifumi Aoyama

Constitutive Regulation of Cardiac Fatty Acid Metabolism through Peroxisome Proliferator-activated Receptor  Associated with Age-dependent Cardiac Toxicity
J. Biol. Chem. 2000 275: 22293-22299. [Abstract] [Full Text] [PDF]  

Polly A. Hansen, Bess Adkins Marshall, May Chen, John O. Holloszy, and Mike Mueckler

Transgenic Overexpression of Hexokinase II in Skeletal Muscle Does Not Increase Glucose Disposal in Wild-type or Glut1-overexpressing Mice
J. Biol. Chem. 2000 275: 22381-22386. [Abstract] [Full Text] [PDF]  

Glycobiology and Extracellular Matrices:

Richard L. Easton, Manish S. Patankar, Gary F. Clark, Howard R. Morris, and Anne Dell

Pregnancy-associated Changes in the Glycosylation of Tamm-Horsfall Glycoprotein. EXPRESSION OF SIALYL LEWIS^x SEQUENCES ON CORE 2 TYPE O-GLYCANS DERIVED FROM UROMODULIN
J. Biol. Chem. 2000 275: 21928-21938. [Abstract] [Full Text] [PDF]  

Takeo Tsuda, Yoshitaka Ikeda, and Naoyuki Taniguchi

The Asn-420-linked Sugar Chain in Human Epidermal Growth Factor Receptor Suppresses Ligand-independent Spontaneous Oligomerization. POSSIBLE ROLE OF A SPECIFIC SUGAR CHAIN IN CONTROLLABLE RECEPTOR ACTIVATION
J. Biol. Chem. 2000 275: 21988-21994. [Abstract] [Full Text] [PDF]  

Jiquan Q. Zhang, Gavin Nicoll, Claire Jones, and Paul R. Crocker

Siglec-9, a Novel Sialic Acid Binding Member of the Immunoglobulin Superfamily Expressed Broadly on Human Blood Leukocytes
J. Biol. Chem. 2000 275: 22121-22126. [Abstract] [Full Text] [PDF]  

Takashi Angata and Ajit Varki

Cloning, Characterization, and Phylogenetic Analysis of Siglec-9, a New Member of the CD33-related Group of Siglecs. EVIDENCE FOR CO-EVOLUTION WITH SIALIC ACID SYNTHESIS PATHWAYS
J. Biol. Chem. 2000 275: 22127-22135. [Abstract] [Full Text] [PDF]  

Deqin Li, Charles C. Clark, and Jeanne C. Myers

Basement Membrane Zone Type XV Collagen Is a Disulfide-bonded Chondroitin Sulfate Proteoglycan in Human Tissues and Cultured Cells
J. Biol. Chem. 2000 275: 22339-22347. [Abstract] [Full Text] [PDF]  

Tomomi Hirosaki, Hiroto Mizushima, Yoshiaki Tsubota, Kayano Moriyama, and Kaoru Miyazaki

Structural Requirement of Carboxyl-terminal Globular Domains of Laminin 3 Chain for Promotion of Rapid Cell Adhesion and Migration by Laminin-5
J. Biol. Chem. 2000 275: 22495-22502. [Abstract] [Full Text] [PDF]  

Membrane Transport Structure Function and Biogenesis:

Carol Austin, Ina Hinners, and Sharon A. Tooze

Direct and GTP-dependent Interaction of ADP-ribosylation Factor 1 with Clathrin Adaptor Protein AP-1 on Immature Secretory Granules
J. Biol. Chem. 2000 275: 21862-21869. [Abstract] [Full Text] [PDF]  

Ting Xu and Michael Forgac

Subunit D (Vma8p) of the Yeast Vacuolar H⁺-ATPase Plays a Role in Coupling of Proton Transport and ATP Hydrolysis
J. Biol. Chem. 2000 275: 22075-22081. [Abstract] [Full Text] [PDF]  

Stanislav Berjukow, Rainer Marksteiner, Franz Gapp, Martina J. Sinnegger, and Steffen Hering

Molecular Mechanism of Calcium Channel Block by Isradipine. ROLE OF A DRUG-INDUCED INACTIVATED CHANNEL CONFORMATION
J. Biol. Chem. 2000 275: 22114-22120. [Abstract] [Full Text] [PDF]  

Mitsuaki Tabuchi, Tamotsu Yoshimori, Kazuhito Yamaguchi, Tsutomu Yoshida, and Fumio Kishi

Human NRAMP2/DMT1, Which Mediates Iron Transport across Endosomal Membranes, Is Localized to Late Endosomes and Lysosomes in HEp-2 Cells
J. Biol. Chem. 2000 275: 22220-22228. [Abstract] [Full Text] [PDF]  

Katsuya Yamada, Masanori Nakata, Naoki Horimoto, Mikako Saito, Hideaki Matsuoka, and Nobuya Inagaki

Measurement of Glucose Uptake and Intracellular Calcium Concentration in Single, Living Pancreatic -Cells
J. Biol. Chem. 2000 275: 22278-22283. [Abstract] [Full Text] [PDF]  

Caroline T. Paine, Michael L. Paine, Wen Luo, Curtis T. Okamoto, S. Petter Lyngstadaas, and Malcolm L. Snead

A Tuftelin-interacting Protein (TIP39) Localizes to the Apical Secretory Pole of Mouse Ameloblasts
J. Biol. Chem. 2000 275: 22284-22292. [Abstract] [Full Text] [PDF]  

Feng Jiang, Michael T. Ryan, Michael Schlame, Ming Zhao, Zhiming Gu, Martin Klingenberg, Nikolaus Pfanner, and Miriam L. Greenberg

Absence of Cardiolipin in the crd1 Null Mutant Results in Decreased Mitochondrial Membrane Potential and Reduced Mitochondrial Function
J. Biol. Chem. 2000 275: 22387-22394. [Abstract] [Full Text] [PDF]  

Christian Lerche, Constanze R. Scherer, Guiscard Seebohm, Christian Derst, Aguan D. Wei, Andreas E. Busch, and Klaus Steinmeyer

Molecular Cloning and Functional Expression of KCNQ5, a Potassium Channel Subunit That May Contribute to Neuronal M-current Diversity
J. Biol. Chem. 2000 275: 22395-22400. [Abstract] [Full Text] [PDF]  

Damaraju Sambasivarao, Raymond J. Turner, Joanne L. Simala-Grant, Gillian Shaw, Jing Hu, and Joel H. Weiner

Multiple Roles for the Twin Arginine Leader Sequence of Dimethyl Sulfoxide Reductase of Escherichia coli
J. Biol. Chem. 2000 275: 22526-22531. [Abstract] [Full Text] [PDF]  

Dirk Hagemann, Meike Kuschel, Takehiko Kuramochi, Weizhong Zhu, Heping Cheng, and Rui-Ping Xiao

Frequency-encoding Thr¹⁷ Phospholamban Phosphorylation Is Independent of Ser¹⁶ Phosphorylation in Cardiac Myocytes
J. Biol. Chem. 2000 275: 22532-22536. [Abstract] [Full Text] [PDF]  

Mechanisms Of Signal Transduction:

Kristine A. Henningfeld, Sepand Rastegar, Guido Adler, and Walter Knöchel

Smad1 and Smad4 Are Components of the Bone Morphogenetic Protein-4 (BMP-4)-induced Transcription Complex of the Xvent-2B Promoter
J. Biol. Chem. 2000 275: 21827-21835. [Abstract] [Full Text] [PDF]  

Masaru Shimizu, John T. Potts, Jr., and Thomas J. Gardella

Minimization of Parathyroid Hormone. NOVEL AMINO-TERMINAL PARATHYROID HORMONE FRAGMENTS WITH ENHANCED POTENCY IN ACTIVATING THE TYPE-1 PARATHYROID HORMONE RECEPTOR
J. Biol. Chem. 2000 275: 21836-21843. [Abstract] [Full Text] [PDF]  

Ana L. Giannini, Maria d. M. Vivanco, and Robert M. Kypta

-Catenin Inhibits -Catenin Signaling by Preventing Formation of a -Catenin·T-cell Factor·DNA Complex
J. Biol. Chem. 2000 275: 21883-21888. [Abstract] [Full Text] [PDF]  

Michael Emerson, Angela R. Travis, Roslyn Bathgate, Tomas Stojanov, David I. Cook, Elizabeth Harding, David P. Lu, and Christopher O'Neill

Characterization and Functional Significance of Calcium Transients in the 2-Cell Mouse Embryo Induced by an Autocrine Growth Factor
J. Biol. Chem. 2000 275: 21905-21913. [Abstract] [Full Text] [PDF]  

Fan Meng, Qiang Wei, Mary T. Hoversten, Larry P. Taylor, and Huda Akil

Switching Agonist/Antagonist Properties of Opiate Alkaloids at the  Opioid Receptor Using Mutations Based on the Structure of the Orphanin FQ Receptor
J. Biol. Chem. 2000 275: 21939-21945. [Abstract] [Full Text] [PDF]  

Marie-France Carlier, Pierre Nioche, Isabelle Broutin-L'Hermite, Rajaa Boujemaa, Christophe Le Clainche, Coumaran Egile, Christiane Garbay, Arnaud Ducruix, Philippe Sansonetti, and Dominique Pantaloni

GRB2 Links Signaling to Actin Assembly by Enhancing Interaction of Neural Wiskott-Aldrich Syndrome Protein (N-WASp) with Actin-related Protein (ARP2/3) Complex
J. Biol. Chem. 2000 275: 21946-21952. [Abstract] [Full Text] [PDF]  

Yvonne Werbonat, Nina Kleutges, Karl H. Jakobs, and Chris J. van Koppen

Essential Role of Dynamin in Internalization of M₂ Muscarinic Acetylcholine and Angiotensin AT_1A Receptors
J. Biol. Chem. 2000 275: 21969-21974. [Abstract] [Full Text] [PDF]  

Heinz Baumann, Yanping Wang, Carl D. Richards, Craig A. Jones, Tom A. Black, and Kenneth W. Gross

Endotoxin-induced Renal Inflammatory Response. ONCOSTATIN M AS A MAJOR MEDIATOR OF SUPPRESSED RENIN EXPRESSION
J. Biol. Chem. 2000 275: 22014-22019. [Abstract] [Full Text] [PDF]  

Marguerite A. Cervin and George B. Spiegelman

A Role for Asp⁷⁵ in Domain Interactions in the Bacillus subtilis Response Regulator Spo0A
J. Biol. Chem. 2000 275: 22025-22030. [Abstract] [Full Text] [PDF]  

Tara L. Baker, Michelle A. Booden, and Janice E. Buss

S-Nitrosocysteine Increases Palmitate Turnover on Ha-Ras in NIH 3T3 Cells
J. Biol. Chem. 2000 275: 22037-22047. [Abstract] [Full Text] [PDF]  

Renate Hofer-Warbinek, Johannes A. Schmid, Christian Stehlik, Bernd R. Binder, Joachim Lipp, and Rainer de Martin

Activation of NF-B by XIAP, the X Chromosome-linked Inhibitor of Apoptosis, in Endothelial Cells Involves TAK1
J. Biol. Chem. 2000 275: 22064-22068. [Abstract] [Full Text] [PDF]  

Daniel J. Carucci, Adam A. Witney, David K. Muhia, David C. Warhurst, Pauline Schaap, Marcel Meima, Ji-Liang Li, Martin C. Taylor, John M. Kelly, and David A. Baker

Guanylyl Cyclase Activity Associated with Putative Bifunctional Integral Membrane Proteins in Plasmodium falciparum
J. Biol. Chem. 2000 275: 22147-22156. [Abstract] [Full Text] [PDF]  

Jason G. Williams, Jonelle K. Drugan, Gwan-Su Yi, Geoffrey J. Clark, Channing J. Der, and Sharon L. Campbell

Elucidation of Binding Determinants and Functional Consequences of Ras/Raf-Cysteine-rich Domain Interactions
J. Biol. Chem. 2000 275: 22172-22179. [Abstract] [Full Text] [PDF]  

Jian Wu, Shu-Ling Liu, Jian-Liang Zhu, Pamela A. Norton, Shunsuke Nojiri, Jan B. Hoek, and Mark A. Zern

Roles of Tissue Transglutaminase in Ethanol-induced Inhibition of Hepatocyte Proliferation and 1-Adrenergic Signal Transduction
J. Biol. Chem. 2000 275: 22213-22219. [Abstract] [Full Text] [PDF]  

Ying-Jie Wang, Roland B. Gregory, and Greg J. Barritt

Regulation of F-actin and Endoplasmic Reticulum Organization by the Trimeric G-protein G_i2 in Rat Hepatocytes. IMPLICATION FOR THE ACTIVATION OF STORE-OPERATED Ca²⁺ INFLOW
J. Biol. Chem. 2000 275: 22229-22237. [Abstract] [Full Text] [PDF]  

Jean-Philippe Gratton, Jason Fontana, Daniel S. O'Connor, Guillermo García-Cardeña, Timothy J. McCabe, and William C. Sessa

Reconstitution of an Endothelial Nitric-oxide Synthase (eNOS), hsp90, and Caveolin-1 Complex in Vitro. EVIDENCE THAT hsp90 FACILITATES CALMODULIN STIMULATED DISPLACEMENT OF eNOS FROM CAVEOLIN-1
J. Biol. Chem. 2000 275: 22268-22272. [Abstract] [Full Text] [PDF]  

Dietmar Abraham, Klaus Podar, Margit Pacher, Markus Kubicek, Natascha Welzel, Brian A. Hemmings, Stephen M. Dilworth, Harald Mischak, Walter Kolch, and Manuela Baccarini

Raf-1-associated Protein Phosphatase 2A as a Positive Regulator of Kinase Activation
J. Biol. Chem. 2000 275: 22300-22304. [Abstract] [Full Text] [PDF]  

Craig A. Aspinwall, Wei-Jun Qian, Michael G. Roper, Rohit N. Kulkarni, C. Ronald Kahn, and Robert T. Kennedy

Roles of Insulin Receptor Substrate-1, Phosphatidylinositol 3-Kinase, and Release of Intracellular Ca²⁺ Stores in Insulin-stimulated Insulin Secretion in -Cells
J. Biol. Chem. 2000 275: 22331-22338. [Abstract] [Full Text] [PDF]  

Isa M. Hussaini, Larry R. Karns, Griffith Vinton, Joan E. Carpenter, Gerard T. Redpath, Julianne J. Sando, and Scott R. VandenBerg

Phorbol 12-Myristate 13-Acetate Induces Protein Kinase C-specific Proliferative Response in Astrocytic Tumor Cells
J. Biol. Chem. 2000 275: 22348-22354. [Abstract] [Full Text] [PDF]  

Richard T. Premont, Audrey Claing, Nicolas Vitale, Stephen J. Perry, and Robert J. Lefkowitz

The GIT Family of ADP-ribosylation Factor GTPase-activating Proteins. FUNCTIONAL DIVERSITY OF GIT2 THROUGH ALTERNATIVE SPLICING
J. Biol. Chem. 2000 275: 22373-22380. [Abstract] [Full Text] [PDF]  

Shu Wakino, Ulrich Kintscher, Sarah Kim, Fen Yin, Willa A. Hsueh, and Ronald E. Law

Peroxisome Proliferator-activated Receptor  Ligands Inhibit Retinoblastoma Phosphorylation and G₁  S Transition in Vascular Smooth Muscle Cells
J. Biol. Chem. 2000 275: 22435-22441. [Abstract] [Full Text] [PDF]  

Ping Zhang, Yi-Zhe Wang, Elliott Kagan, and James C. Bonner

Peroxynitrite Targets the Epidermal Growth Factor Receptor, Raf-1, and MEK Independently to Activate MAPK
J. Biol. Chem. 2000 275: 22479-22486. [Abstract] [Full Text] [PDF]  

Kevin E. Fogarty, Jackie F. Kidd, Angelina Turner, Jeremy N. Skepper, Jeff Carmichael, and Peter Thorn

Microtubules Regulate Local Ca²⁺ Spiking in Secretory Epithelial Cells
J. Biol. Chem. 2000 275: 22487-22494. [Abstract] [Full Text] [PDF]  

Kambiz Amdjadi and Bartholomew M. Sefton

Ultraviolet Light-induced Stimulation of the JNK Mitogen-activated Protein Kinase in the Absence of Src Family Tyrosine Kinase Activation
J. Biol. Chem. 2000 275: 22520-22525. [Abstract] [Full Text] [PDF]  

Chrystelle Garat, Vicki Van Putten, Zaki A. Refaat, Christina Dessev, Sun-Young Han, and Raphael A. Nemenoff

Induction of Smooth Muscle -Actin in Vascular Smooth Muscle Cells by Arginine Vasopressin Is Mediated by c-Jun Amino-terminal Kinases and p38 Mitogen-activated Protein Kinase
J. Biol. Chem. 2000 275: 22537-22543. [Abstract] [Full Text] [PDF]  

Jesús Balsinde, María A. Balboa, and Edward A. Dennis

Identification of a Third Pathway for Arachidonic Acid Mobilization and Prostaglandin Production in Activated P388D₁ Macrophage-like Cells
J. Biol. Chem. 2000 275: 22544-22549. [Abstract] [Full Text] [PDF]  

Yi-Zhe Wang, Ping Zhang, Annette B. Rice, and James C. Bonner

Regulation of Interleukin-1-induced Platelet-derived Growth Factor Receptor- Expression in Rat Pulmonary Myofibroblasts by p38 Mitogen-activated Protein Kinase
J. Biol. Chem. 2000 275: 22550-22557. [Abstract] [Full Text] [PDF]  

Hong Zhang, Henry Hoff, and Christian Sell

Insulin-like Growth Factor I-mediated Degradation of Insulin Receptor Substrate-1 Is Inhibited by Epidermal Growth Factor in Prostate Epithelial Cells
J. Biol. Chem. 2000 275: 22558-22562. [Abstract] [Full Text] [PDF]  

Hong-Duk Youn, Christina M. Grozinger, and Jun O. Liu

Calcium Regulates Transcriptional Repression of Myocyte Enhancer Factor 2 by Histone Deacetylase 4
J. Biol. Chem. 2000 275: 22563-22567. [Abstract] [Full Text] [PDF]  

Robin M. Gibson, William P. Schiemann, Lisa B. Prichard, John M. Reno, Lowell H. Ericsson, and Neil M. Nathanson

Phosphorylation of Human gp130 at Ser-782 Adjacent to the Di-leucine Internalization Motif. EFFECTS ON EXPRESSION AND SIGNALING
J. Biol. Chem. 2000 275: 22574-22582. [Abstract] [Full Text] [PDF]  

Francine L. Roudabush, Kristen L. Pierce, Stuart Maudsley, Khuda Dad Khan, and Louis M. Luttrell

Transactivation of the EGF Receptor Mediates IGF-1-stimulated Shc Phosphorylation and ERK1/2 Activation in COS-7 Cells
J. Biol. Chem. 2000 275: 22583-22589. [Abstract] [Full Text] [PDF]  

Molecular Basis Of Cell and Developmental Biology:

Hidenao Toyoda, Akiko Kinoshita-Toyoda, Bethany Fox, and Scott B. Selleck

Structural Analysis of Glycosaminoglycans in Animals Bearing Mutations in sugarless, sulfateless, and tout-velu. DROSOPHILA HOMOLOGUES OF VERTEBRATE GENES ENCODING GLYCOSAMINOGLYCAN BIOSYNTHETIC ENZYMES
J. Biol. Chem. 2000 275: 21856-21861. [Abstract] [Full Text] [PDF]  

Manuel Collado, René H. Medema, Isabel García-Cao, Marlène L. N. Dubuisson, Marta Barradas, Janet Glassford, Carmen Rivas, Boudewijn M. T. Burgering, Manuel Serrano, and Eric W.-F. Lam

Inhibition of the Phosphoinositide 3-Kinase Pathway Induces a Senescence-like Arrest Mediated by p27^Kip1
J. Biol. Chem. 2000 275: 21960-21968. [Abstract] [Full Text] [PDF]  

Robin Leguy, Ronald Melki, Dominique Pantaloni, and Marie-France Carlier

Monomeric -Tubulin Nucleates Microtubules
J. Biol. Chem. 2000 275: 21975-21980. [Abstract] [Full Text] [PDF]  

Eduardo A. Garcia-Gras, Ping Chi, and E. Aubrey Thompson

Glucocorticoid-mediated Destabilization of Cyclin D3 mRNA Involves RNA-Protein Interactions in the 3'-Untranslated Region of the mRNA
J. Biol. Chem. 2000 275: 22001-22008. [Abstract] [Full Text] [PDF]  

Grace Jones, Davy Jones, Lei Zhou, Hermann Steller, and Yanxia Chu

Deterin, a New Inhibitor of Apoptosis from Drosophila melanogaster
J. Biol. Chem. 2000 275: 22157-22165. [Abstract] [Full Text] [PDF]  

Amy K. Walker, Raymond See, Ceri Batchelder, Thip Kophengnavong, J. Timothy Gronniger, Yang Shi, and T. Keith Blackwell

A Conserved Transcription Motif Suggesting Functional Parallels between Caenorhabditis elegans SKN-1 and Cap`n'Collar-related Basic Leucine Zipper Proteins
J. Biol. Chem. 2000 275: 22166-22171. [Abstract] [Full Text] [PDF]  

Katherine M. Brendza, Christopher A. Sontag, William M. Saxton, and Susan P. Gilbert

A Kinesin Mutation That Uncouples Motor Domains and Desensitizes the -Phosphate Sensor
J. Biol. Chem. 2000 275: 22187-22195. [Abstract] [Full Text] [PDF]  

Casper Caspersen, Peter Sten Pedersen, and Marek Treiman

The Sarco/Endoplasmic Reticulum Calcium-ATPase 2b Is an Endoplasmic Reticulum Stress-inducible Protein
J. Biol. Chem. 2000 275: 22363-22372. [Abstract] [Full Text] [PDF]  

Hitomi Sano, Hirofumi Chiba, Daisuke Iwaki, Hitoshi Sohma, Dennis R. Voelker, and Yoshio Kuroki

Surfactant Proteins A and D Bind CD14 by Different Mechanisms
J. Biol. Chem. 2000 275: 22442-22451. [Abstract] [Full Text] [PDF]  

Brett A. Wagner, Garry R. Buettner, Larry W. Oberley, Christine J. Darby, and C. Patrick Burns

Myeloperoxidase Is Involved in H₂O₂-induced Apoptosis of HL-60 Human Leukemia Cells
J. Biol. Chem. 2000 275: 22461-22469. [Abstract] [Full Text] [PDF]  

Beth Drees, Evelyne Friederich, Julie Fradelizi, Daniel Louvard, Mary C. Beckerle, and Roy M. Golsteyn

Characterization of the Interaction between Zyxin and Members of the Ena/Vasodilator-stimulated Phosphoprotein Family of Proteins
J. Biol. Chem. 2000 275: 22503-22511. [Abstract] [Full Text] [PDF]  

Tatsuo Kinashi, Koko Katagiri, Shin-ichi Watanabe, Bart Vanhaesebroeck, Julian Downward, and Kiyoshi Takatsu

Distinct Mechanisms of ₅₁ Integrin Activation by Ha-Ras and R-Ras
J. Biol. Chem. 2000 275: 22590-22596. [Abstract] [Full Text] [PDF]  

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