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Table of Contents: Aug 25 2000; 275 (34)   [Index by Author] 
       Editorial
       Accelerated Publications
       DNA: Replication Repair and Recombination
       Genes: Structure and Regulation
       RNA: Structure Metabolism and Catalysis
       Protein Synthesis Post-Translation Modification and Degradation
       Genomics Proteomics and Bioinformatics
       Protein Structure and Folding
       Enzyme Catalysis and Regulation
       Metabolism and Bioenergetics
       Glycobiology and Extracellular Matrices
       Lipids and Lipoproteins
       Membrane Transport Structure Function and Biogenesis
       Mechanisms Of Signal Transduction
       Molecular Basis Of Cell and Developmental Biology
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Editorial:

JBC electronic submission required (starting September 1, 2000)
J. Biol. Chem. 2000 275: 25877. First Published ; 10.1074/jbc.275.34.25877 [Full Text] [PDF]  


Accelerated Publications:

Konstantin A. Lukyanov, Arkady F. Fradkov, Nadya G. Gurskaya, Mikhail V. Matz, Yulii A. Labas, Aleksandr P. Savitsky, Mikhail L. Markelov, Andrey G. Zaraisky, Xiaoning Zhao, Yu Fang, Wenyan Tan, and Sergey A. Lukyanov
Natural Animal Coloration Can Be Determined by a Nonfluorescent Green Fluorescent Protein Homolog
J. Biol. Chem. 2000 275: 25879-25882. First Published on June 13, 2000; 10.1074/jbc.C000338200 [Abstract] [Full Text] [PDF]  


DNA: Replication Repair and Recombination:

Nancy Klemperer, Dan Zhang, Maija Skangalis, and Mike O'Donnell
Cross-utilization of the beta  Sliding Clamp by Replicative Polymerases of Evolutionary Divergent Organisms
J. Biol. Chem. 2000 275: 26136-26143. First Published on June 12, 2000; 10.1074/jbc.M002566200 [Abstract] [Full Text] [PDF]  

Pearl Chang and Kenneth J. Marians
Identification of a Region of Escherichia coli DnaB Required for Functional Interaction with DnaG at the Replication Fork
J. Biol. Chem. 2000 275: 26187-26195. First Published on May 31, 2000; 10.1074/jbc.M001800200 [Abstract] [Full Text] [PDF]  

Ling Chen, Kelly Trujillo, Patrick Sung, and Alan E. Tomkinson
Interactions of the DNA Ligase IV-XRCC4 Complex with DNA Ends and the DNA-dependent Protein Kinase
J. Biol. Chem. 2000 275: 26196-26205. First Published on June 14, 2000; 10.1074/jbc.M000491200 [Abstract] [Full Text] [PDF]  

Kozo Tanaka, Tomoki Hiramoto, Toshikatsu Fukuda, and Kiyoshi Miyagawa
A Novel Human Rad54 Homologue, Rad54B, Associates with Rad51
J. Biol. Chem. 2000 275: 26316-26321. First Published on June 12, 2000; 10.1074/jbc.M910306199 [Abstract] [Full Text] [PDF]  

Matthew A. Burtelow, Scott H. Kaufmann, and Larry M. Karnitz
Retention of the Human Rad9 Checkpoint Complex in Extraction-resistant Nuclear Complexes after DNA Damage
J. Biol. Chem. 2000 275: 26343-26348. First Published on June 13, 2000; 10.1074/jbc.M001244200 [Abstract] [Full Text] [PDF]  

Ana M. Abril, Margarita Salas, and José M. Hermoso
Identification of Residues within Two Regions Involved in Self-association of Viral Histone-like Protein p6 from Phage Ø29
J. Biol. Chem. 2000 275: 26404-26410. First Published on May 26, 2000; 10.1074/jbc.M002739200 [Abstract] [Full Text] [PDF]  

Angela K. Eggleston and Stephen C. West
Cleavage of Holliday Junctions by the Escherichia coli RuvABC Complex
J. Biol. Chem. 2000 275: 26467-26476. First Published on June 12, 2000; 10.1074/jbc.M001496200 [Abstract] [Full Text] [PDF]  

Isao Kuraoka, William R. Kobertz, Rafael R. Ariza, Maureen Biggerstaff, John M. Essigmann, and Richard D. Wood
Repair of an Interstrand DNA Cross-link Initiated by ERCC1-XPF Repair/Recombination Nuclease
J. Biol. Chem. 2000 275: 26632-26636. First Published on July 5, 2000; 10.1074/jbc.C000337200 [Abstract] [Full Text] [PDF]  


Genes: Structure and Regulation:

Fernando Rodriguez-Pascual, Michael Hausding, Irmgard Ihrig-Biedert, Henry Furneaux, Andrew P. Levy, Ulrich Förstermann, and Hartmut Kleinert
Complex Contribution of the 3'-Untranslated Region to the Expressional Regulation of the Human Inducible Nitric-oxide Synthase Gene. INVOLVEMENT OF THE RNA-BINDING PROTEIN HuR
J. Biol. Chem. 2000 275: 26040-26049. First Published on June 19, 2000; 10.1074/jbc.M910460199 [Abstract] [Full Text] [PDF]  

Christina Lyngsø, Guillaine Bouteiller, Christian K. Damgaard, Dorthe Ryom, Sylvia Sanchez-Muñoz, Peder L. Nørby, Bjarne J. Bonven, and Poul Jørgensen
Interaction between the Transcription Factor SPBP and the Positive Cofactor RNF4. AN INTERPLAY BETWEEN PROTEIN BINDING ZINC FINGERS
J. Biol. Chem. 2000 275: 26144-26149. First Published on June 9, 2000; 10.1074/jbc.M003405200 [Abstract] [Full Text] [PDF]  

Carola H. Biederer, Stefan J. Ries, Markus Moser, Monica Florio, Mark A. Israel, Frank McCormick, and Reinhard Buettner
The Basic Helix-Loop-Helix Transcription Factors Myogenin and Id2 Mediate Specific Induction of Caveolin-3 Gene Expression during Embryonic Development
J. Biol. Chem. 2000 275: 26245-26251. First Published on June 1, 2000; 10.1074/jbc.M001430200 [Abstract] [Full Text] [PDF]  

Venugopalan Cheriyath and Ananda L. Roy
Alternatively Spliced Isoforms of TFII-I. COMPLEX FORMATION, NUCLEAR TRANSLOCATION, AND DIFFERENTIAL GENE REGULATION
J. Biol. Chem. 2000 275: 26300-26308. First Published on June 14, 2000; 10.1074/jbc.M002980200 [Abstract] [Full Text] [PDF]  

Irina Tcherepanova, Lokesh Bhattacharyya, Charles S. Rubin, and Jonathan H. Freedman
Aspartic Proteases from the Nematode Caenorhabditis elegans. STRUCTURAL ORGANIZATION AND DEVELOPMENTAL AND CELL-SPECIFIC EXPRESSION OF asp-1
J. Biol. Chem. 2000 275: 26359-26369. First Published on June 14, 2000; 10.1074/jbc.M000956200 [Abstract] [Full Text] [PDF]  

Zea Borok, Xian Li, Valentino F. J. Fernandes, Beiyun Zhou, David K. Ann, and Edward D. Crandall
Differential Regulation of Rat Aquaporin-5 Promoter/Enhancer Activities in Lung and Salivary Epithelial Cells
J. Biol. Chem. 2000 275: 26507-26514. First Published on June 9, 2000; 10.1074/jbc.M910007199 [Abstract] [Full Text] [PDF]  

Nickolai A. Tchurikov, Ludmila G. Chistyakova, Genadii B. Zavilgelsky, Iliya V. Manukhov, Boris K. Chernov, and Yulia B. Golova
Gene-specific Silencing by Expression of Parallel Complementary RNA in Escherichia coli
J. Biol. Chem. 2000 275: 26523-26529. First Published on June 9, 2000; 10.1074/jbc.M002833200 [Abstract] [Full Text] [PDF]  

Venu Raman, Akihiro Tamori, Mustafa Vali, Karen Zeller, Dorian Korz, and Saraswati Sukumar
HOXA5 Regulates Expression of the Progesterone Receptor
J. Biol. Chem. 2000 275: 26551-26555. First Published on June 29, 2000; 10.1074/jbc.C000324200 [Abstract] [Full Text] [PDF]  

Mark Baer and Peter F. Johnson
Generation of Truncated C/EBPbeta Isoforms by in Vitro Proteolysis
J. Biol. Chem. 2000 275: 26582-26590. First Published on June 15, 2000; 10.1074/jbc.M004268200 [Abstract] [Full Text] [PDF]  

Robyn D. Moir, Karen V. Puglia, and Ian M. Willis
Interactions between the Tetratricopeptide Repeat-containing Transcription Factor TFIIIC131 and Its Ligand, TFIIIB70. EVIDENCE FOR A CONFORMATIONAL CHANGE IN THE COMPLEX
J. Biol. Chem. 2000 275: 26591-26598. First Published on June 19, 2000; 10.1074/jbc.M003991200 [Abstract] [Full Text] [PDF]  

Travis J. Antes, Sheryl A. Goodart, Cathy Huynh, Meghan Sullivan, Stephen G. Young, and Beatriz Levy-Wilson
Identification and Characterization of a 315-Base Pair Enhancer, Located More than 55 Kilobases 5' of the Apolipoprotein B Gene, That Confers Expression in the Intestine
J. Biol. Chem. 2000 275: 26637-26648. First Published on June 19, 2000; 10.1074/jbc.M003025200 [Abstract] [Full Text] [PDF]  

Travis J. Antes, Jean Chen, Allen D. Cooper, and Beatriz Levy-Wilson
The Nuclear Matrix Protein CDP Represses Hepatic Transcription of the Human Cholesterol-7alpha Hydroxylase Gene
J. Biol. Chem. 2000 275: 26649-26660. First Published on June 26, 2000; 10.1074/jbc.M002852200 [Abstract] [Full Text] [PDF]  


RNA: Structure Metabolism and Catalysis:

Alicia Solórzano, Nieves Rodríguez-Cousiño, Rosa Esteban, and Tsutomu Fujimura
Persistent Yeast Single-stranded RNA Viruses Exist in Vivo as Genomic RNA·RNA Polymerase Complexes in 1:1 Stoichiometry
J. Biol. Chem. 2000 275: 26428-26435. First Published on May 31, 2000; 10.1074/jbc.M002281200 [Abstract] [Full Text] [PDF]  

Gilles Pagès, Edurne Berra, Julie Milanini, Andrew P. Levy, and Jacques Pouysségur
Stress-activated Protein Kinases (JNK and p38/HOG) Are Essential for Vascular Endothelial Growth Factor mRNA Stability
J. Biol. Chem. 2000 275: 26484-26491. First Published on June 9, 2000; 10.1074/jbc.M002104200 [Abstract] [Full Text] [PDF]  


Protein Synthesis Post-Translation Modification and Degradation:

Uyen T. Phan, Balasubramanian Arunachalam, and Peter Cresswell
Gamma-Interferon-inducible Lysosomal Thiol Reductase (GILT). MATURATION, ACTIVITY, AND MECHANISM OF ACTION
J. Biol. Chem. 2000 275: 25907-25914. First Published on June 13, 2000; 10.1074/jbc.M003459200 [Abstract] [Full Text] [PDF]  

Joseph Nika, Weimin Yang, Graham D. Pavitt, Alan G. Hinnebusch, and Ernest M. Hannig
Purification and Kinetic Analysis of eIF2B from Saccharomyces cerevisiae
J. Biol. Chem. 2000 275: 26011-26017. First Published on June 13, 2000; 10.1074/jbc.M003718200 [Abstract] [Full Text] [PDF]  

Yong Mao, Shyamal D. Desai, and Leroy F. Liu
SUMO-1 Conjugation to Human DNA Topoisomerase II Isozymes
J. Biol. Chem. 2000 275: 26066-26073. First Published on June 20, 2000; 10.1074/jbc.M001831200 [Abstract] [Full Text] [PDF]  

Larry Takemoto and Daniel Boyle
Specific Glutamine and Asparagine Residues of gamma -S Crystallin Are Resistant to in Vivo Deamidation
J. Biol. Chem. 2000 275: 26109-26112. First Published on June 7, 2000; 10.1074/jbc.M002809200 [Abstract] [Full Text] [PDF]  

Zhiping Wang, Ruth Juttermann, and Paul D. Soloway
TIMP-2 Is Required for Efficient Activation of proMMP-2 in Vivo
J. Biol. Chem. 2000 275: 26411-26415. First Published on May 25, 2000; 10.1074/jbc.M001270200 [Abstract] [Full Text] [PDF]  

John J. Caterina, Susan Yamada, Nancy C. M. Caterina, Glenn Longenecker, Kenn Holmbäck, Joanne Shi, Audra E. Yermovsky, Jeffrey A. Engler, and Henning Birkedal-Hansen
Inactivating Mutation of the Mouse Tissue Inhibitor of Metalloproteinases-2(Timp-2) Gene Alters ProMMP-2 Activation
J. Biol. Chem. 2000 275: 26416-26422. First Published on May 25, 2000; 10.1074/jbc.M001271200 [Abstract] [Full Text] [PDF]  

Ruifen Bi, Yongqi Rong, Anne Bernard, Michel Khrestchatisky, and Michel Baudry
Src-mediated Tyrosine Phosphorylation of NR2 Subunits of N-Methyl-D-Aspartate Receptors Protects from Calpain-mediated Truncation of Their C-terminal Domains
J. Biol. Chem. 2000 275: 26477-26483. First Published on June 8, 2000; 10.1074/jbc.M003763200 [Abstract] [Full Text] [PDF]  


Genomics Proteomics and Bioinformatics:

Nabil A. Elshourbagy, Robert S. Ames, Laura R. Fitzgerald, James J. Foley, Jon K. Chambers, Philip G. Szekeres, Nicholas A. Evans, Dulcie B. Schmidt, Peter T. Buckley, George M. Dytko, Paul R. Murdock, Graeme Milligan, D. Alex Groarke, Kong B. Tan, Usman Shabon, Parvathi Nuthulaganti, Da Yuan Wang, Shelagh Wilson, Derk J. Bergsma, and Henry M. Sarau
Receptor for the Pain Modulatory Neuropeptides FF and AF Is an Orphan G Protein-coupled Receptor
J. Biol. Chem. 2000 275: 25965-25971. First Published on June 12, 2000; 10.1074/jbc.M004515200 [Abstract] [Full Text] [PDF]  


Protein Structure and Folding:

George V. Avvakumov, Yves A. Muller, and Geoffrey L. Hammond
Steroid-binding Specificity of Human Sex Hormone-binding Globulin Is Influenced by Occupancy of a Zinc-binding Site
J. Biol. Chem. 2000 275: 25920-25925. First Published on June 19, 2000; 10.1074/jbc.M004484200 [Abstract] [Full Text] [PDF]  

Patricia Hermand, Martine Huet, Isabelle Callebaut, Pierre Gane, Eveliina Ihanus, Carl G. Gahmberg, Jean-Pierre Cartron, and Pascal Bailly
Binding Sites of Leukocyte beta 2 Integrins (LFA-1, Mac-1) on the Human ICAM-4/LW Blood Group Protein
J. Biol. Chem. 2000 275: 26002-26010. First Published on June 8, 2000; 10.1074/jbc.M002823200 [Abstract] [Full Text] [PDF]  

Maoqing Dong, Yan W. Asmann, Mengwei Zang, Delia I. Pinon, and Laurence J. Miller
Identification of Two Pairs of Spatially Approximated Residues within the Carboxyl Terminus of Secretin and Its Receptor
J. Biol. Chem. 2000 275: 26032-26039. First Published on June 19, 2000; 10.1074/jbc.M000612200 [Abstract] [Full Text] [PDF]  

Martin W. Bader, Tong Xie, Chang-An Yu, and James C. A. Bardwell
Disulfide Bonds Are Generated by Quinone Reduction
J. Biol. Chem. 2000 275: 26082-26088. First Published on June 14, 2000; 10.1074/jbc.M003850200 [Abstract] [Full Text] [PDF]  

J. Fernando Díaz, Rik Strobe, Yves Engelborghs, André A. Souto, and José M. Andreu
Molecular Recognition of Taxol by Microtubules. KINETICS AND THERMODYNAMICS OF BINDING OF FLUORESCENT TAXOL DERIVATIVES TO AN EXPOSED SITE
J. Biol. Chem. 2000 275: 26265-26276. First Published on May 18, 2000; 10.1074/jbc.M003120200 [Abstract] [Full Text] [PDF]  

Westley John Friesen and Gideon Dreyfuss
Specific Sequences of the Sm and Sm-like (Lsm) Proteins Mediate Their Interaction with the Spinal Muscular Atrophy Disease Gene Product (SMN)
J. Biol. Chem. 2000 275: 26370-26375. First Published on June 12, 2000; 10.1074/jbc.M003299200 [Abstract] [Full Text] [PDF]  

Hui Chen, Michelle Deere, Jacqueline T. Hecht, and Jack Lawler
Cartilage Oligomeric Matrix Protein Is a Calcium-binding Protein, and a Mutation in Its Type 3 Repeats Causes Conformational Changes
J. Biol. Chem. 2000 275: 26538-26544. First Published on June 13, 2000; 10.1074/jbc.M909780199 [Abstract] [Full Text] [PDF]  


Enzyme Catalysis and Regulation:

Q. Khai Huynh, Hymavathi Boddupalli, Sharon A. Rouw, Carol M. Koboldt, Troii Hall, Cindy Sommers, Scott D. Hauser, Jennifer L. Pierce, Rodney G. Combs, Beverly A. Reitz, Judy A. Diaz-Collier, Robin A. Weinberg, Becky L. Hood, Bryan F. Kilpatrick, and Catherine S. Tripp
Characterization of the Recombinant IKK1/IKK2 Heterodimer. MECHANISMS REGULATING KINASE ACTIVITY
J. Biol. Chem. 2000 275: 25883-25891. First Published on May 22, 2000; 10.1074/jbc.M000296200 [Abstract] [Full Text] [PDF]  

Lam H. Nguyen, Jan P. Erzberger, Jeffrey Root, and David M. Wilson, III
The Human Homolog of Escherichia coli Orn Degrades Small Single-stranded RNA and DNA Oligomers
J. Biol. Chem. 2000 275: 25900-25906. First Published on June 12, 2000; 10.1074/jbc.M002672200 [Abstract] [Full Text] [PDF]  

Andrew T. Bender, Mikiya Nakatsuka, and Yoichi Osawa
Heme Insertion, Assembly, and Activation of Apo-neuronal Nitric-oxide Synthase in Vitro
J. Biol. Chem. 2000 275: 26018-26023. First Published on June 14, 2000; 10.1074/jbc.M003316200 [Abstract] [Full Text] [PDF]  

Ikuko Sagami, Yuko Sato, Simon Daff, and Toru Shimizu
Aromatic Residues and Neighboring Arg414 in the (6R)-5,6,7,8-Tetrahydro-L-Biopterin Binding Site of Full-length Neuronal Nitric-oxide Synthase Are Crucial in Catalysis and Heme Reduction with NADPH
J. Biol. Chem. 2000 275: 26150-26157. First Published on June 8, 2000; 10.1074/jbc.M000534200 [Abstract] [Full Text] [PDF]  

Xinyi Huang and Frank M. Raushel
Restricted Passage of Reaction Intermediates through the Ammonia Tunnel of Carbamoyl Phosphate Synthetase
J. Biol. Chem. 2000 275: 26233-26240. First Published on June 13, 2000; 10.1074/jbc.M004521200 [Abstract] [Full Text] [PDF]  

Carolyn M. Ott, Bryan D. Smith, Archie R. Portis, Jr., and Robert J. Spreitzer
Activase Region on Chloroplast Ribulose-1,5-bisphosphate Carboxylase/Oxygenase. NONCONSERVATIVE SUBSTITUTION IN THE LARGE SUBUNIT ALTERS SPECIES SPECIFICITY OF PROTEIN INTERACTION
J. Biol. Chem. 2000 275: 26241-26244. First Published on June 16, 2000; 10.1074/jbc.M004580200 [Abstract] [Full Text] [PDF]  

Toshihiko Takeuchi, Jennifer L. Harris, Wei Huang, Kelly W. Yan, Shaun R. Coughlin, and Charles S. Craik
Cellular Localization of Membrane-type Serine Protease 1 and Identification of Protease-activated Receptor-2 and Single-chain Urokinase-type Plasminogen Activator as Substrates
J. Biol. Chem. 2000 275: 26333-26342. First Published on May 30, 2000; 10.1074/jbc.M002941200 [Abstract] [Full Text] [PDF]  

Carol A. Chrestensen, David W. Starke, and John J. Mieyal
Acute Cadmium Exposure Inactivates Thioltransferase (Glutaredoxin), Inhibits Intracellular Reduction of Protein-glutathionyl-mixed Disulfides, and Initiates Apoptosis
J. Biol. Chem. 2000 275: 26556-26565. First Published on June 14, 2000; 10.1074/jbc.M004097200 [Abstract] [Full Text] [PDF]  

Rongbao Zhao, Steven Titus, Feng Gao, Richard G. Moran, and I. David Goldman
Molecular Analysis of Murine Leukemia Cell Lines Resistant to 5,10-Dideazatetrahydrofolate Identifies Several Amino Acids Critical to the Function of Folylpolyglutamate Synthetase
J. Biol. Chem. 2000 275: 26599-26606. First Published on June 15, 2000; 10.1074/jbc.M002580200 [Abstract] [Full Text] [PDF]  

Xiang-Ping Huang, Naofumi Kagami, Hideshi Inoue, Masaki Kojima, Takao Kimura, Osamu Makabe, Koichi Suzuki, and Kenji Takahashi
Identification of a Glutamic Acid and an Aspartic Acid Residue Essential for Catalytic Activity of Aspergillopepsin II, a Non-pepsin Type Acid Proteinase
J. Biol. Chem. 2000 275: 26607-26614. First Published on June 14, 2000; 10.1074/jbc.M910243199 [Abstract] [Full Text] [PDF]  


Metabolism and Bioenergetics:

Nandita Jha, Octavian Jurma, Giovanna Lalli, Yi Liu, Edward Harvey Pettus, John Timothy Greenamyre, Rui-Ming Liu, Henry Jay Forman, and Julie Kay Andersen
Glutathione Depletion in PC12 Results in Selective Inhibition of Mitochondrial Complex I Activity. IMPLICATIONS FOR PARKINSON'S DISEASE
J. Biol. Chem. 2000 275: 26096-26101. First Published on June 8, 2000; 10.1074/jbc.M000120200 [Abstract] [Full Text] [PDF]  

Romina Paola Barbagallo, Cécile Breyton, and Giovanni Finazzi
Kinetic Effects of the Electrochemical Proton Gradient on Plastoquinone Reduction at the Qi Site of the Cytochrome b6f Complex
J. Biol. Chem. 2000 275: 26121-26127. First Published on June 23, 2000; 10.1074/jbc.M002299200 [Abstract] [Full Text] [PDF]  


Glycobiology and Extracellular Matrices:

Maria Ringvall, Johan Ledin, Katarina Holmborn, Toin van Kuppevelt, Fredrik Ellin, Inger Eriksson, Anne-Mari Olofsson, Lena Kjellén, and Erik Forsberg
Defective Heparan Sulfate Biosynthesis and Neonatal Lethality in Mice Lacking N-Deacetylase/N-Sulfotransferase-1
J. Biol. Chem. 2000 275: 25926-25930. First Published on June 13, 2000; 10.1074/jbc.C000359200 [Abstract] [Full Text] [PDF]  

Yutaka Kariya, Mamoru Kyogashima, Kiyoshi Suzuki, Takako Isomura, Takashi Sakamoto, Katsuyuki Horie, Masayuki Ishihara, Ryo Takano, Kaeko Kamei, and Saburo Hara
Preparation of Completely 6-O-Desulfated Heparin and Its Ability to Enhance Activity of Basic Fibroblast Growth Factor
J. Biol. Chem. 2000 275: 25949-25958. First Published on June 2, 2000; 10.1074/jbc.M004140200 [Abstract] [Full Text] [PDF]  

W. Thomas Forsee, Robert T. Cartee, and Janet Yother
Biosynthesis of Type 3 Capsular Polysaccharide in Streptococcus pneumoniae. ENZYMATIC CHAIN RELEASE BY AN ABORTIVE TRANSLOCATION PROCESS
J. Biol. Chem. 2000 275: 25972-25978. First Published on June 14, 2000; 10.1074/jbc.M002613200 [Abstract] [Full Text] [PDF]  


Lipids and Lipoproteins:

Lennart Asp, Catharina Claesson, Jan Borén, and Sven-Olof Olofsson
ADP-ribosylation Factor 1 and Its Activation of Phospholipase D Are Important for the Assembly of Very Low Density Lipoproteins
J. Biol. Chem. 2000 275: 26285-26292. First Published on June 7, 2000; 10.1074/jbc.M003520200 [Abstract] [Full Text] [PDF]  

Vladimir R. Babaev, Mayur B. Patel, Clay F. Semenkovich, Sergio Fazio, and MacRae F. Linton
Macrophage Lipoprotein Lipase Promotes Foam Cell Formation and Atherosclerosis in Low Density Lipoprotein Receptor-deficient Mice
J. Biol. Chem. 2000 275: 26293-26299. First Published on June 16, 2000; 10.1074/jbc.M002423200 [Abstract] [Full Text] [PDF]  

Amber Luong, Voe C. Hannah, Michael S. Brown, and Joseph L. Goldstein
Molecular Characterization of Human Acetyl-CoA Synthetase, an Enzyme Regulated by Sterol Regulatory Element-binding Proteins
J. Biol. Chem. 2000 275: 26458-26466. First Published on June 7, 2000; 10.1074/jbc.M004160200 [Abstract] [Full Text] [PDF]  


Membrane Transport Structure Function and Biogenesis:

Mark F. Vickers, Sylvia Y. M. Yao, Stephen A. Baldwin, James D. Young, and Carol E. Cass
Nucleoside Transporter Proteins of Saccharomyces cerevisiae. DEMONSTRATION OF A TRANSPORTER (FUI1) WITH HIGH URIDINE SELECTIVITY IN PLASMA MEMBRANES AND A TRANSPORTER (FUN26) WITH BROAD NUCLEOSIDE SELECTIVITY IN INTRACELLULAR MEMBRANES
J. Biol. Chem. 2000 275: 25931-25938. First Published on May 25, 2000; 10.1074/jbc.M000239200 [Abstract] [Full Text] [PDF]  

Zhiyi Xie, Eric Turk, and Ernest M. Wright
Characterization of the Vibrio parahaemolyticus Na+/Glucose Cotransporter. A BACTERIAL MEMBER OF THE SODIUM/GLUCOSE TRANSPORTER (SGLT) FAMILY
J. Biol. Chem. 2000 275: 25959-25964. First Published on June 13, 2000; 10.1074/jbc.M002687200 [Abstract] [Full Text] [PDF]  

Katja Köhler, Ian C. Forster, Georg Lambert, Jürg Biber, and Heini Murer
The Functional Unit of the Renal Type IIa Na+/Pi Cotransporter Is a Monomer
J. Biol. Chem. 2000 275: 26113-26120. First Published on June 19, 2000; 10.1074/jbc.M003564200 [Abstract] [Full Text] [PDF]  

Fubito Nakatsu, Machie Sakuma, Yo Matsuo, Hisashi Arase, Sho Yamasaki, Nobuhiro Nakamura, Takashi Saito, and Hiroshi Ohno
A Di-leucine Signal in the Ubiquitin Moiety. POSSIBLE INVOLVEMENT IN UBIQUITINATION-MEDIATED ENDOCYTOSIS
J. Biol. Chem. 2000 275: 26213-26219. First Published on May 18, 2000; 10.1074/jbc.M907720199 [Abstract] [Full Text] [PDF]  

Camillo Peracchia, Anna Sotkis, Xiao G. Wang, Lillian L. Peracchia, and Anthony Persechini
Calmodulin Directly Gates Gap Junction Channels
J. Biol. Chem. 2000 275: 26220-26224. First Published on June 13, 2000; 10.1074/jbc.M004007200 [Abstract] [Full Text] [PDF]  


Mechanisms Of Signal Transduction:

Olga Zolle, Alison M. Lawrie, and Alec W. M. Simpson
Activation of the Particulate and Not the Soluble Guanylate Cyclase Leads to the Inhibition of Ca2+ Extrusion through Localized Elevation of cGMP
J. Biol. Chem. 2000 275: 25892-25899. First Published on June 12, 2000; 10.1074/jbc.M000786200 [Abstract] [Full Text] [PDF]  

Claus Wittpoth, Klaus Scholich, Jennifer D. Bilyeu, and Tarun B. Patel
Adenylyl Cyclase Regulates Signal Onset via the Inhibitory GTP-binding Protein, Gi
J. Biol. Chem. 2000 275: 25915-25919. First Published on June 13, 2000; 10.1074/jbc.M001687200 [Abstract] [Full Text] [PDF]  

Shougang Zhuang, John T. Demirs, and Irene E. Kochevar
p38 Mitogen-activated Protein Kinase Mediates Bid Cleavage, Mitochondrial Dysfunction, and Caspase-3 Activation during Apoptosis Induced by Singlet Oxygen but Not by Hydrogen Peroxide
J. Biol. Chem. 2000 275: 25939-25948. First Published on June 2, 2000; 10.1074/jbc.M001185200 [Abstract] [Full Text] [PDF]  

Sunhong Kim, Youngsun Jung, Dohoon Kim, Hyongjong Koh, and Jongkyeong Chung
Extracellular Zinc Activates p70 S6 Kinase through the Phosphatidylinositol 3-Kinase Signaling Pathway
J. Biol. Chem. 2000 275: 25979-25984. First Published on June 12, 2000; 10.1074/jbc.M001975200 [Abstract] [Full Text] [PDF]  

Ian Sabroe, Michael J. Peck, Berend Jan Van Keulen, Annelies Jorritsma, Graham Simmons, Paul R. Clapham, Timothy J. Williams, and James E. Pease
A Small Molecule Antagonist of Chemokine Receptors CCR1 and CCR3. POTENT INHIBITION OF EOSINOPHIL FUNCTION AND CCR3-MEDIATED HIV-1 ENTRY
J. Biol. Chem. 2000 275: 25985-25992. First Published on June 14, 2000; 10.1074/jbc.M908864199 [Abstract] [Full Text] [PDF]  

Kejin Zhu, Balazs Debreceni, Rong Li, and Yi Zheng
Identification of Rho GTPase-dependent Sites in the Dbl Homology Domain of Oncogenic Dbl That Are Required for Transformation
J. Biol. Chem. 2000 275: 25993-26001. First Published on June 14, 2000; 10.1074/jbc.M003780200 [Abstract] [Full Text] [PDF]  

Andrew Hsing, Douglas V. Faller, and Cyrus Vaziri
DNA-damaging Aryl Hydrocarbons Induce Mdm2 Expression via p53-independent Post-transcriptional Mechanisms
J. Biol. Chem. 2000 275: 26024-26031. First Published on June 15, 2000; 10.1074/jbc.M002455200 [Abstract] [Full Text] [PDF]  

Harmeet Malhi, Adil N. Irani, Pankaj Rajvanshi, Sylvia O. Suadicani, David C. Spray, Thomas V. McDonald, and Sanjeev Gupta
KATP Channels Regulate Mitogenically Induced Proliferation in Primary Rat Hepatocytes and Human Liver Cell Lines. IMPLICATIONS FOR LIVER GROWTH CONTROL AND POTENTIAL THERAPEUTIC TARGETING
J. Biol. Chem. 2000 275: 26050-26057. First Published on June 20, 2000; 10.1074/jbc.M001576200 [Abstract] [Full Text] [PDF]  

Da-Pei Li, Sumudra Periyasamy, Thomas J. Jones, and Edwin R. Sánchez
Heat and Chemical Shock Potentiation of Glucocorticoid Receptor Transactivation Requires Heat Shock Factor (HSF) Activity. MODULATION OF HSF BY VANADATE AND WORTMANNIN
J. Biol. Chem. 2000 275: 26058-26065. First Published on June 20, 2000; 10.1074/jbc.M004502200 [Abstract] [Full Text] [PDF]  

Jun Liu and David L. Brautigan
Glycogen Synthase Association with the Striated Muscle Glycogen-targeting Subunit of Protein Phosphatase-1. SYNTHASE ACTIVATION INVOLVES SCAFFOLDING REGULATED BY beta -ADRENERGIC SIGNALING
J. Biol. Chem. 2000 275: 26074-26081. First Published on June 15, 2000; 10.1074/jbc.M003843200 [Abstract] [Full Text] [PDF]  

Susan R. George, Theresa Fan, Zhidong Xie, Roderick Tse, Vincent Tam, George Varghese, and Brian F. O'Dowd
Oligomerization of µ- and delta -Opioid Receptors. GENERATION OF NOVEL FUNCTIONAL PROPERTIES
J. Biol. Chem. 2000 275: 26128-26135. First Published on June 6, 2000; 10.1074/jbc.M000345200 [Abstract] [Full Text] [PDF]  

Elena S. Trepakova, Peter Csutora, Dacia L. Hunton, Richard B. Marchase, Richard A. Cohen, and Victoria M. Bolotina
Calcium Influx Factor Directly Activates Store-operated Cation Channels in Vascular Smooth Muscle Cells
J. Biol. Chem. 2000 275: 26158-26163. First Published on June 12, 2000; 10.1074/jbc.M004666200 [Abstract] [Full Text] [PDF]  

Jing Bao, Iris Alroy, Hadassa Waterman, Eyal D. Schejter, Chaya Brodie, Jean Gruenberg, and Yosef Yarden
Threonine Phosphorylation Diverts Internalized Epidermal Growth Factor Receptors from a Degradative Pathway to the Recycling Endosome
J. Biol. Chem. 2000 275: 26178-26186. First Published on May 17, 2000; 10.1074/jbc.M002367200 [Abstract] [Full Text] [PDF]  

Rita Vaiskunaite, Vyacheslav Adarichev, Heinz Furthmayr, Tohru Kozasa, Andrei Gudkov, and Tatyana A. Voyno-Yasenetskaya
Conformational Activation of Radixin by G13 Protein alpha  Subunit
J. Biol. Chem. 2000 275: 26206-26212. First Published on May 17, 2000; 10.1074/jbc.M001863200 [Abstract] [Full Text] [PDF]  

Barbara Belisle and Arie Abo
N-Formyl Peptide Receptor Ligation Induces Rac-dependent Actin Reorganization through Gbeta gamma Subunits and Class Ia Phosphoinositide 3-Kinases
J. Biol. Chem. 2000 275: 26225-26232. First Published on June 7, 2000; 10.1074/jbc.M002743200 [Abstract] [Full Text] [PDF]  

Emily Vereker, Veronica Campbell, Elizabeth Roche, Edel McEntee, and Marina A. Lynch
Lipopolysaccharide Inhibits Long Term Potentiation in the Rat Dentate Gyrus by Activating Caspase-1
J. Biol. Chem. 2000 275: 26252-26258. First Published on June 15, 2000; 10.1074/jbc.M002226200 [Abstract] [Full Text] [PDF]  

Mette M. Rosenkilde, Thomas N. Kledal, Peter J. Holst, and Thue W. Schwartz
Selective Elimination of High Constitutive Activity or Chemokine Binding in the Human Herpesvirus 8 Encoded Seven Transmembrane Oncogene ORF74
J. Biol. Chem. 2000 275: 26309-26315. First Published on June 6, 2000; 10.1074/jbc.M003800200 [Abstract] [Full Text] [PDF]  

Dianne L. DeCamp, Teresa M. Thompson, Frederic J. de Sauvage, and Michael R. Lerner
Smoothened Activates Galpha i-mediated Signaling in Frog Melanophores
J. Biol. Chem. 2000 275: 26322-26327. First Published on June 1, 2000; 10.1074/jbc.M004055200 [Abstract] [Full Text] [PDF]  

Teresita Bellido, Michael Huening, Mihali Raval-Pandya, Stavros C. Manolagas, and Sylvia Christakos
Calbindin-D28k Is Expressed in Osteoblastic Cells and Suppresses Their Apoptosis by Inhibiting Caspase-3 Activity
J. Biol. Chem. 2000 275: 26328-26332. First Published on June 1, 2000; 10.1074/jbc.M003600200 [Abstract] [Full Text] [PDF]  

Laurent Guillemot, Arlette Levy, Zhizhuang Joe Zhao, Gilbert Béréziat, and Bernard Rothhut
The Protein-tyrosine Phosphatase SHP-2 Is Required during Angiotensin II-mediated Activation of Cyclin D1 Promoter in CHO-AT1A Cells
J. Biol. Chem. 2000 275: 26349-26358. First Published on June 7, 2000; 10.1074/jbc.M001614200 [Abstract] [Full Text] [PDF]  

Heike Keilhack, Ulf Hellman, Jolanda van Hengel, Frans van Roy, Jasminka Godovac-Zimmermann, and Frank-D. Böhmer
The Protein-tyrosine Phosphatase SHP-1 Binds to and Dephosphorylates p120 Catenin
J. Biol. Chem. 2000 275: 26376-26384. First Published on June 1, 2000; 10.1074/jbc.M001315200 [Abstract] [Full Text] [PDF]  

Ko Kotani, Wataru Ogawa, Mitsuru Hashiramoto, Tetsuo Onishi, Shigeo Ohno, and Masato Kasuga
Inhibition of Insulin-induced Glucose Uptake by Atypical Protein Kinase C Isotype-specific Interacting Protein in 3T3-L1 Adipocytes
J. Biol. Chem. 2000 275: 26390-26395. First Published on June 26, 2000; 10.1074/jbc.M002537200 [Abstract] [Full Text] [PDF]  

Rosa Gasa, Per B. Jensen, Hal K. Berman, Matthew J. Brady, Anna A. DePaoli-Roach, and Christopher B. Newgard
Distinctive Regulatory and Metabolic Properties of Glycogen-targeting Subunits of Protein Phosphatase-1 (PTG, GL, GM/RGl) Expressed in Hepatocytes
J. Biol. Chem. 2000 275: 26396-26403. First Published on June 21, 2000; 10.1074/jbc.M002427200 [Abstract] [Full Text] [PDF]  

Susana López-Ongil, Veronica Senchak, Marta Saura, Carlos Zaragoza, Michael Ames, Barbara Ballermann, Manuel Rodríguez-Puyol, Diego Rodríguez-Puyol, and Charles J. Lowenstein
Superoxide Regulation of Endothelin-converting Enzyme
J. Biol. Chem. 2000 275: 26423-26427. First Published on May 31, 2000; 10.1074/jbc.M000767200 [Abstract] [Full Text] [PDF]  

Imanol Arozarena, David S. Aaronson, David Matallanas, Victoria Sanz, Nuria Ajenjo, Stephan P. Tenbaum, Hidemi Teramoto, Tadashi Ighishi, Juan C. Zabala, J. Silvio Gutkind, and Piero Crespo
The Rho Family GTPase Cdc42 Regulates the Activation of Ras/MAP Kinase by the Exchange Factor Ras-GRF
J. Biol. Chem. 2000 275: 26441-26448. First Published on June 5, 2000; 10.1074/jbc.M002992200 [Abstract] [Full Text] [PDF]  

Shiho Ohmori, Norio Sakai, Yasuhito Shirai, Hideyuki Yamamoto, Eishichi Miyamoto, Nobuyoshi Shimizu, and Naoaki Saito
Importance of Protein Kinase C Targeting for the Phosphorylation of Its Substrate, Myristoylated Alanine-rich C-kinase Substrate
J. Biol. Chem. 2000 275: 26449-26457. First Published on June 5, 2000; 10.1074/jbc.M003588200 [Abstract] [Full Text] [PDF]  

Peter Dube, Anthony DeCostanzo, and James B. Konopka
Interaction between Transmembrane Domains Five and Six of the alpha -Factor Receptor
J. Biol. Chem. 2000 275: 26492-26499. First Published on June 8, 2000; 10.1074/jbc.M002767200 [Abstract] [Full Text] [PDF]  

S. Jaharul Haque, Phyllis C. Harbor, and Bryan R. G. Williams
Identification of Critical Residues Required for Suppressor of Cytokine Signaling-specific Regulation of Interleukin-4 Signaling
J. Biol. Chem. 2000 275: 26500-26506. First Published on June 8, 2000; 10.1074/jbc.M003727200 [Abstract] [Full Text] [PDF]  

Alexey N. Pronin, Andrew J. Morris, Andrei Surguchov, and Jeffrey L. Benovic
Synucleins Are a Novel Class of Substrates for G Protein-coupled Receptor Kinases
J. Biol. Chem. 2000 275: 26515-26522. First Published on June 13, 2000; 10.1074/jbc.M003542200 [Abstract] [Full Text] [PDF]  

Kent A. Fagan, Karen E. Smith, and Dermot M. F. Cooper
Regulation of the Ca2+-inhibitable Adenylyl Cyclase Type VI by Capacitative Ca2+ Entry Requires Localization in Cholesterol-rich Domains
J. Biol. Chem. 2000 275: 26530-26537. First Published on June 7, 2000; 10.1074/jbc.M001369200 [Abstract] [Full Text] [PDF]  

Ignazio Castagliuolo, Leyla Valenick, Jennifer Liu, and Charalabos Pothoulakis
Epidermal Growth Factor Receptor Transactivation Mediates Substance P-induced Mitogenic Responses in U-373 MG Cells
J. Biol. Chem. 2000 275: 26545-26550. First Published on June 8, 2000; 10.1074/jbc.M003990200 [Abstract] [Full Text] [PDF]  

David K. Wooten, Xiaoling Xie, David Bartos, Ruth A. Busche, Gregory D. Longmore, and Stephanie S. Watowich
Cytokine Signaling through Stat3 Activates Integrins, Promotes Adhesion, and Induces Growth Arrest in the Myeloid Cell Line 32D
J. Biol. Chem. 2000 275: 26566-26575. First Published on June 16, 2000; 10.1074/jbc.M003495200 [Abstract] [Full Text] [PDF]  

Takiko Hatai, Atsushi Matsuzawa, Seiji Inoshita, Yoshiyuki Mochida, Takayuki Kuroda, Kazuhiro Sakamaki, Keisuke Kuida, Shin Yonehara, Hidenori Ichijo, and Kohsuke Takeda
Execution of Apoptosis Signal-regulating Kinase 1 (ASK1)-induced Apoptosis by the Mitochondria-dependent Caspase Activation
J. Biol. Chem. 2000 275: 26576-26581. First Published on June 9, 2000; 10.1074/jbc.M003412200 [Abstract] [Full Text] [PDF]  

Hanguan Liu, Daniel Palmer, Sandra L. Jimmo, Douglas G. Tilley, Heather A. Dunkerley, Stephen C. Pang, and Donald H. Maurice
Expression of Phosphodiesterase 4D (PDE4D) Is Regulated by Both the Cyclic AMP-dependent Protein Kinase and Mitogen-activated Protein Kinase Signaling Pathways. A POTENTIAL MECHANISM ALLOWING FOR THE COORDINATED REGULATION OF PDE4D ACTIVITY AND EXPRESSION IN CELLS
J. Biol. Chem. 2000 275: 26615-26624. First Published on June 12, 2000; 10.1074/jbc.M001634200 [Abstract] [Full Text] [PDF]  

Oleg Tikhomirov and Graham Carpenter
Geldanamycin Induces ErbB-2 Degradation by Proteolytic Fragmentation
J. Biol. Chem. 2000 275: 26625-26631. First Published on June 20, 2000; 10.1074/jbc.M003114200 [Abstract] [Full Text] [PDF]  


Molecular Basis Of Cell and Developmental Biology:

Ozgur Ogut and Jian-Ping Jin
Cooperative Interaction between Developmentally Regulated Troponin T and Tropomyosin Isoforms in the Absence of F-actin
J. Biol. Chem. 2000 275: 26089-26095. First Published on June 7, 2000; 10.1074/jbc.M910360199 [Abstract] [Full Text] [PDF]  

Louis Ragolia, Qian Zuo, and Najma Begum
Inhibition of Myogenesis by Depletion of the Glycogen-associated Regulatory Subunit of Protein Phosphatase-1 in Rat Skeletal Muscle Cells
J. Biol. Chem. 2000 275: 26102-26108. First Published on June 13, 2000; 10.1074/jbc.M001955200 [Abstract] [Full Text] [PDF]  

Pedro M. Matias, Peter Donner, Ricardo Coelho, Monica Thomaz, Cristina Peixoto, Sofia Macedo, Norbert Otto, Simone Joschko, Peter Scholz, Anja Wegg, Siegfried Bäsler, Martina Schäfer, Ursula Egner, and Maria Arménia Carrondo
Structural Evidence for Ligand Specificity in the Binding Domain of the Human Androgen Receptor. IMPLICATIONS FOR PATHOGENIC GENE MUTATIONS
J. Biol. Chem. 2000 275: 26164-26171. First Published on June 5, 2000; 10.1074/jbc.M004571200 [Abstract] [Full Text] [PDF]  

Carolina Abramovich, Wei-Feng Shen, Nicolas Pineault, Suzan Imren, Ben Montpetit, Corey Largman, and R. Keith Humphries
Functional Cloning and Characterization of a Novel Nonhomeodomain Protein That Inhibits the Binding of PBX1-HOX Complexes to DNA
J. Biol. Chem. 2000 275: 26172-26177. First Published on May 23, 2000; 10.1074/jbc.M001323200 [Abstract] [Full Text] [PDF]  

Sean P. Kessler, Theresa M. Rowe, Janette B. Gomos, Patricia M. Kessler, and Ganes C. Sen
Physiological Non-equivalence of the Two Isoforms of Angiotensin-converting Enzyme
J. Biol. Chem. 2000 275: 26259-26264. First Published on May 30, 2000; 10.1074/jbc.M004006200 [Abstract] [Full Text] [PDF]  

M. Paul Murphy, Sacha N. Uljon, Paul E. Fraser, Abdul Fauq, Hilary A. Lookingbill, Kirk A. Findlay, Tawnya E. Smith, Patrick A. Lewis, D. Chris McLendon, Rong Wang, and Todd E. Golde
Presenilin 1 Regulates Pharmacologically Distinct gamma -Secretase Activities. IMPLICATIONS FOR THE ROLE OF PRESENILIN IN gamma -SECRETASE CLEAVAGE
J. Biol. Chem. 2000 275: 26277-26284. First Published on May 17, 2000; 10.1074/jbc.M002812200 [Abstract] [Full Text] [PDF]  

Raymond R. Schleef and Trinette L. Chuang
Protease Inhibitor 10 Inhibits Tumor Necrosis Factor alpha -induced Cell Death. EVIDENCE FOR THE FORMATION OF INTRACELLULAR HIGH Mr PROTEASE INHIBITOR 10-CONTAINING COMPLEXES
J. Biol. Chem. 2000 275: 26385-26389. First Published on June 27, 2000; 10.1074/jbc.C000389200 [Abstract] [Full Text] [PDF]  

Lourdes Herreros, José Luis Rodríguez-Fernández, Michael C. Brown, José L. Alonso-Lebrero, Carlos Cabañas, Francisco Sánchez-Madrid, Natividad Longo, Christopher E. Turner, and Paloma Sánchez-Mateos
Paxillin Localizes to the Lymphocyte Microtubule Organizing Center and Associates with the Microtubule Cytoskeleton
J. Biol. Chem. 2000 275: 26436-26440. First Published on June 5, 2000; 10.1074/jbc.M003970200 [Abstract] [Full Text] [PDF]  


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